Research Topics
| Luc ThibervilleSummaryCountry: France Publications
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Detail Information
Publications
In vivo imaging of the bronchial wall microstructure using fibered confocal fluorescence microscopyLuc Thiberville
Clinique Pneumologique, Hôpital Charles Nicolle CHU de Rouen, 1 rue de Germont, 76031 Rouen Cedex, France
Am J Respir Crit Care Med 175:22-31. 2007..Fibered confocal fluorescence microscopy (FCFM) is a new technique that produces microscopic imaging of a living tissue through a 1-mm fiberoptic probe that can be introduced into the working channel of the bronchoscope...
[New diagnostic tools in lung cancers]Luc Thiberville
CHU de Rouen, Clinique Pneumologique, Hopital Charles Nicolle, 76031 Rouen Cedex
Rev Prat 59:925-31. 2009..In the near future, these techniques should reduce the need for invasive surgical procedures during lung cancer staging...
Confocal fluorescence endomicroscopy of the human airwaysLuc Thiberville
Rouen University Hospital, CHU de Rouen, 1 rue de Germont, 76031 Rouen Cedex, France
Proc Am Thorac Soc 6:444-9. 2009..This article reviews the capabilities and possible limitations of confocal microendoscopy for in vivo proximal and distal lung explorations...
Human in vivo fluorescence microimaging of the alveolar ducts and sacs during bronchoscopyL Thiberville
Clinique Pneumologique, Hopital Charles Nicolle, CHU de Rouen, Rouen Cedex, France
Eur Respir J 33:974-85. 2009..Fibred confocal fluorescence microscopy enables accurate exploration of the peripheral lung in vivo in both smokers and nonsmokers...
[Diagnosis of lung cancer. Fluorescence bronchoscopy]L Thiberville
Clinique Pneumologique, Hopital Charles Nicolle, Centre Hospitalier et Universitaire de Rouen, 1, rue de Germont, 76031 Rouen Cedex
Rev Mal Respir 23:16S17-16S22. 2006..This paper reviews the principal applications and results of the use of autofluorescence endoscopy in high risk individuals, as well as innovative endoscopic approaches using the fluorescence properties of the respiratory tract...
[Fluorescence endoscopy of the respiratory tract]L Thiberville
Clinique Pneumologique, Hopital Charles Nicolle, Centre Hospitalier et Universitaire de Rouen, Rouen Cedex, France
Rev Mal Respir 24:6S22-7. 2007..This paper reviews the principal applications and results of the use of autofluorescence endoscopy in high risk individuals as well as innovative endoscopic approaches using the fluorescent properties of the respiratory tract...
Bronchoscopic advances: on the way to the cellsLuc Thiberville
Clinique Pneumologique, Rouen University Hospital, and QuantIF LITIS EA 4108, Faculte de Medecine Pharmacie, Rouen University, Rouen, France
Respiration 79:441-9. 2010..Whereas promising pioneer work has recently been published, careful assessment is required before these methods find a place in the evaluation strategy of early lung cancer and other lung diseases...
Molecular predictive factors for progression of high-grade preinvasive bronchial lesionsMathieu Salaun
Clinique Pneumologique, Hôpital Charles Nicolle CHU de Rouen, 1 rue de Germont, 76031 Rouen Cedex, France
Am J Respir Crit Care Med 177:880-6. 2008..Many molecular alterations are present in preinvasive lesions, but none has been assessed to predict the evolution of the lesions...
Occupational and nonoccupational factors associated with high grade bronchial pre-invasive lesionsC Paris
Dept of Occupational Diseases, Rouen University Hospital, Rouen, France
Eur Respir J 21:332-41. 2003....
A model of spontaneous lung metastases visualised in fresh host tissue by green fluorescent protein expressionS Paris
INSERM U295, Faculte de Medecine, Rouen, France
Clin Exp Metastasis 17:817-22. 1999..The H460M(GFP) cell line allowed to follow the seeding and development of spontaneous lung metastases and may be considered a simple and powerful tool to study each step of the metastasis to screen new anticancer drugs...
Smoking status, occupational asbestos exposure and bronchial location of lung cancerChristophe Paris
Occupational Diseases Department, Rouen University Hospital, 1 rue de Germont, 76031 Rouen, Cedex, France
Lung Cancer 40:17-24. 2003....
[Confocal endomicroscopy of the lung: from the bronchus to the alveolus]M Salaun
Clinique Pneumologique, CHU Charles Nicolle, 1, rue de Germont, 76000 Rouen, France
Rev Mal Respir 27:579-88. 2010....
[Low grade pulmonary sarcoma preceding the discovery of a uterine primary]E Staub
Clinique Pneumologique, , CHU de Rouen
Rev Mal Respir 20:437-41. 2003..In both cases their finding justifies the search for a uterine primary by immunohistochemical examination for oestrogen and progesterone receptors as well as pelvic ultrasound or even magnetic resonance imaging...
[Standards, Options and Recommendations for the management of non-small cell lung carcinoma patients]Alain Depierre
Bull Cancer 90:151-66. 2003..This is a short version of the SOR guideline covering diagnosis, treatment and follow-up and includes the algorithms for the management of patients with non-small cell lung cancer...
Intense paraneoplastic neutrophilic leukemoid reaction related to a G-CSF-secreting lung sarcomaFabrice Jardin
Department of Haematology and EMI 9906, IFRMP 23, Centre Henri Becquerel, Rouen, France
Am J Hematol 80:243-5. 2005..Adjunction of the patient's serum to CD34+ cell cultures induced a 12.3-fold increase in CD15+ cells, demonstrating the serum's capacity to induce myeloid differentiation...
Preoperative chemotherapy followed by surgery compared with primary surgery in resectable stage I (except T1N0), II, and IIIa non-small-cell lung cancerAlain Depierre
Chest Disease Department, J Minjoz University Hospital, 25030 Besancon Cedex, France
J Clin Oncol 20:247-53. 2002..To evaluate whether preoperative chemotherapy (PCT) could improve survival in resectable stage I (except T1N0), II, and IIIA non-small-cell lung cancer (NSCLC)...
Inhibition of tumor growth and metastatic spreading by overexpression of inter-alpha-trypsin inhibitor family chainsSébastien Paris
INSERM EMI 9906, IFRMP, Faculte de Medecine Pharmacie, Rouen, France
Int J Cancer 97:615-20. 2002..In vitro, ITI-L expression significantly decreased chemotaxis and ITI-HI and ITI-H3 expression increased cell attachment. These results argue for the antitumoral or antimetastatic properties of ITI-L, -HI and -H3 chains...
Aberrant methylation of the CDKN2a/p16INK4a gene promoter region in preinvasive bronchial lesions: a prospective study in high-risk patients without invasive cancerAude Lamy
INSERM EMI 9906, IFRMP, Faculte de Medecine Pharmacie, Rouen, France
Int J Cancer 100:189-93. 2002....
Re: Sex-related differences in bronchial epithelial changes associated with tobacco smokingChristophe Paris
J Natl Cancer Inst 95:242-3; author reply 243-4. 2003
[Lung tumors, primary and secondary]Luc Thiberville
Clinique Pneumologique, , 76031 Rouen
Rev Prat 54:2065-77; quiz 2077. 2004
Phase III study of adjuvant vaccination with Bec2/bacille Calmette-Guerin in responding patients with limited-disease small-cell lung cancer (European Organisation for Research and Treatment of Cancer 08971-08971B; Silva Study)Giuseppe Giaccone
Division of Medical Oncology, Vrije Universiteit Medical Center, 1117 De Boelelaan, Amsterdam, The Netherlands
J Clin Oncol 23:6854-64. 2005..We assessed whether Bec2/bacille Calmette-Guerin (BCG) vaccination prolongs survival in patients with limited-disease small-cell lung cancer (SCLC) after a major response to chemotherapy and chest radiation...
