Stephanie Thebault

Summary

Country: France

Publications

  1. ncbi request reprint Differential role of transient receptor potential channels in Ca2+ entry and proliferation of prostate cancer epithelial cells
    Stephanie Thebault
    Laboratoire de Physiologie Cellulaire, Institut National de la Sante et de la Recherche Medicale, Centre National de la Recherche Scientifique, Universite des Sciences et Technologies de Lille, Villeneuve d Ascq, France
    Cancer Res 66:2038-47. 2006
  2. ncbi request reprint Two types of store-operated Ca2+ channels with different activation modes and molecular origin in LNCaP human prostate cancer epithelial cells
    Fabien Vanden Abeele
    Laboratoire de Physiologie Cellulaire, INSERM EMI 0228, Universite des Sciences et Technologies de Lille, Bat SN3, 59655 Villeneuve d Ascq, France
    J Biol Chem 279:30326-37. 2004
  3. pmc Prostate cell differentiation status determines transient receptor potential melastatin member 8 channel subcellular localization and function
    Gabriel Bidaux
    INSERM U800, Equipe Labellisée par la Ligue Nationale Contre le Cancer, Villeneuve d Ascq, France
    J Clin Invest 117:1647-57. 2007
  4. pmc Cytoskeleton reorganization as an alternative mechanism of store-operated calcium entry control in neuroendocrine-differentiated cells
    Karine Vanoverberghe
    INSERM, U 1003, Equipe Labellisée par la Ligue Nationale Contre le Cancer, Villeneuve d Ascq, France
    PLoS ONE 7:e45615. 2012
  5. ncbi request reprint Novel role of cold/menthol-sensitive transient receptor potential melastatine family member 8 (TRPM8) in the activation of store-operated channels in LNCaP human prostate cancer epithelial cells
    Stephanie Thebault
    Laboratoire de Physiologie Cellulaire, INSERM EMI 0228, USTL SN3, 59655 Villeneuve d Ascq, France
    J Biol Chem 280:39423-35. 2005
  6. pmc Alpha1-adrenergic receptors activate Ca(2+)-permeable cationic channels in prostate cancer epithelial cells
    Stephanie Thebault
    Laboratoire de Physiologie Cellulaire, Institut National de la Santé et de la Recherche Médicale INSERM EMI 0228, Villeneuve d Ascq, France
    J Clin Invest 111:1691-701. 2003
  7. ncbi request reprint Prospects for prostate cancer imaging and therapy using high-affinity TRPM8 activators
    Benjamin Beck
    INSERM, U800, Equipe Labellisee par la Ligue Contre le Cancer, Villeneuve d Ascq F 59650, France
    Cell Calcium 41:285-94. 2007
  8. ncbi request reprint Ca2+-independent phospholipase A2-dependent gating of TRPM8 by lysophospholipids
    Fabien Vanden Abeele
    INSERM U800, Equipe Labellisee par la Ligue Contre le Cancer, Villeneuve d Ascq F 59650, France and Universite Lille 1, Villeneuve d Ascq F 59650, France
    J Biol Chem 281:40174-82. 2006

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Differential role of transient receptor potential channels in Ca2+ entry and proliferation of prostate cancer epithelial cells
    Stephanie Thebault
    Laboratoire de Physiologie Cellulaire, Institut National de la Sante et de la Recherche Medicale, Centre National de la Recherche Scientifique, Universite des Sciences et Technologies de Lille, Villeneuve d Ascq, France
    Cancer Res 66:2038-47. 2006
    ..Our findings show that alpha1-AR signaling requires the coupled activation of TRPC6 channels and NFAT to promote proliferation of hPCE cells and thereby suggest TRPC6 as a novel potential therapeutic target...
  2. ncbi request reprint Two types of store-operated Ca2+ channels with different activation modes and molecular origin in LNCaP human prostate cancer epithelial cells
    Fabien Vanden Abeele
    Laboratoire de Physiologie Cellulaire, INSERM EMI 0228, Universite des Sciences et Technologies de Lille, Bat SN3, 59655 Villeneuve d Ascq, France
    J Biol Chem 279:30326-37. 2004
    ..These results provide new insight into the nature of SOCs and their representation in the single cell type as well as permit reconciliation of current SOC activation hypotheses...
  3. pmc Prostate cell differentiation status determines transient receptor potential melastatin member 8 channel subcellular localization and function
    Gabriel Bidaux
    INSERM U800, Equipe Labellisée par la Ligue Nationale Contre le Cancer, Villeneuve d Ascq, France
    J Clin Invest 117:1647-57. 2007
    ....
  4. pmc Cytoskeleton reorganization as an alternative mechanism of store-operated calcium entry control in neuroendocrine-differentiated cells
    Karine Vanoverberghe
    INSERM, U 1003, Equipe Labellisée par la Ligue Nationale Contre le Cancer, Villeneuve d Ascq, France
    PLoS ONE 7:e45615. 2012
    ..Our data suggest that targeting cytoskeleton-induced pathways of malignant cells together with SOCE-involved channels may prove a useful strategy in the treatment of advanced prostate cancer...
  5. ncbi request reprint Novel role of cold/menthol-sensitive transient receptor potential melastatine family member 8 (TRPM8) in the activation of store-operated channels in LNCaP human prostate cancer epithelial cells
    Stephanie Thebault
    Laboratoire de Physiologie Cellulaire, INSERM EMI 0228, USTL SN3, 59655 Villeneuve d Ascq, France
    J Biol Chem 280:39423-35. 2005
    ....
  6. pmc Alpha1-adrenergic receptors activate Ca(2+)-permeable cationic channels in prostate cancer epithelial cells
    Stephanie Thebault
    Laboratoire de Physiologie Cellulaire, Institut National de la Santé et de la Recherche Médicale INSERM EMI 0228, Villeneuve d Ascq, France
    J Clin Invest 111:1691-701. 2003
    ..Collectively, our results suggest that alpha1-ARs play a role in promoting hPCE cell proliferation via TRP channels...
  7. ncbi request reprint Prospects for prostate cancer imaging and therapy using high-affinity TRPM8 activators
    Benjamin Beck
    INSERM, U800, Equipe Labellisee par la Ligue Contre le Cancer, Villeneuve d Ascq F 59650, France
    Cell Calcium 41:285-94. 2007
    ..The high affinity of this new TRPM8 ligand and the possibility of incorporating a radiohalogen could thus be useful for diagnosis, monitoring and, perhaps, even therapy of prostate cancer...
  8. ncbi request reprint Ca2+-independent phospholipase A2-dependent gating of TRPM8 by lysophospholipids
    Fabien Vanden Abeele
    INSERM U800, Equipe Labellisee par la Ligue Contre le Cancer, Villeneuve d Ascq F 59650, France and Universite Lille 1, Villeneuve d Ascq F 59650, France
    J Biol Chem 281:40174-82. 2006
    ..This mechanism employs chemical rather than physical (temperature change) signaling and thus may be the main regulator of TRPM8 activation in organs not exposed to any essential temperature variations, as in the prostate gland...