Illa Tea

Summary

Country: France

Publications

  1. doi request reprint Simultaneous determination of natural-abundance δ15N values and quantities of individual amino acids in proteins from milk of lactating women and from infant hair using gas chromatography/isotope ratio mass spectrometry
    Illa Tea
    Elucidation of Biosynthesis by Isotopic Spectrometry Group, CEISAM, LUNAM Université, University of Nantes CNRS UMR6230, 2 rue de la Houssiniere, BP 92208, F 44322 Nantes, France
    Rapid Commun Mass Spectrom 27:1345-53. 2013
  2. pmc 1H-NMR-based metabolic profiling of maternal and umbilical cord blood indicates altered materno-foetal nutrient exchange in preterm infants
    Illa Tea
    Elucidation of Biosynthesis by Isotopic Spectrometry Group, Unit for Interdisciplinary Chemistry, Synthesis Analysis Modelling CEISAM, University of Nantes CNRS UMR 6230, Nantes, France
    PLoS ONE 7:e29947. 2012
  3. doi request reprint Determination of the natural abundance δ15N of taurine by gas chromatography-isotope ratio measurement mass spectrometry
    Illa Tea
    Elucidation of Biosynthesis by Isotopic Spectrometry Group, Unit for Interdisciplinary Chemistry Synthesis Analysis Modelling CEISAM, University of Nantes CNRS UMR6230, 2 rue de la Houssiniere, BP 92208, F 44322 Nantes, France
    Rapid Commun Mass Spectrom 24:3380-6. 2010
  4. doi request reprint In situ NMR spectroelectrochemistry for the structure elucidation of unstable intermediate metabolites
    Ugo Bussy
    CNRS, Chimie et Interdisciplinarite Synthese, Analyse et Modélisation CEISAM, UMR 6230, LUNAM Université de Nantes, 2 rue de la Houssiniere, BP 92208, 44322, Nantes Cedex 3, France
    Anal Bioanal Chem 405:5817-24. 2013
  5. ncbi request reprint Determination of the concentration of nitrogenous bio-organic compounds using an isotope ratio mass spectrometer operating in continuous flow mode
    Illa Tea
    Elucidation of Biosynthesis by Isotopic Spectrometry Group, Unit for Interdisciplinary Chemistry Synthesis Analysis Modelling CEISAM, University of Nantes CNRS UMR6230, Nantes, France
    Anal Bioanal Chem 401:1263-71. 2011
  6. pmc Cord blood glutathione depletion in preterm infants: correlation with maternal cysteine depletion
    Alice Kuster
    UMR Physiologie des Adaptations Nutritionnelles, INRA, Universite de Nantes, Nantes, France
    PLoS ONE 6:e27626. 2011
  7. doi request reprint Acebutolol and alprenolol metabolism predictions: comparative study of electrochemical and cytochrome P450-catalyzed reactions using liquid chromatography coupled to high-resolution mass spectrometry
    Ugo Bussy
    LUNAM Université de Nantes, CNRS, Chimie et Interdisciplinarite Synthese, Analyse et Modélisation CEISAM, UMR 6230, 2 rue de la Houssiniere, BP 92208, 44322, Nantes Cedex 3, France
    Anal Bioanal Chem 405:6077-85. 2013
  8. doi request reprint New practical tools for the implementation and use of ultrafast 2D NMR experiments
    Meerakhan Pathan
    CNRS, Chimie et Interdisciplinarite Synthese, Analyse, Modelisation CEISAM, UMR 6230, Faculte des Sciences, Universite de Nantes, BP 92208, 2 rue de la Houssiniere, F 44322 Nantes Cedex 03, France
    Magn Reson Chem 51:168-75. 2013
  9. doi request reprint Maternal and cord blood LC-HRMS metabolomics reveal alterations in energy and polyamine metabolism, and oxidative stress in very-low birth weight infants
    Marie Cécile Alexandre-Gouabau
    UMR Physiologie des Adaptations Nutritionnelles, INRA, IMAD, CRNH, Nantes, France
    J Proteome Res 12:2764-78. 2013
  10. doi request reprint Human baby hair amino acid natural abundance 15N-isotope values are not related to the 15N-isotope values of amino acids in mother's breast milk protein
    Katarzyna M Romek
    Elucidation of Biosynthesis by Isotopic Spectrometry Group, CEISAM, University of Nantes CNRS UMR6230, 2 rue de la Houssiniere, BP 92208, 44322, Nantes, France
    Amino Acids 45:1365-72. 2013

Collaborators

Detail Information

Publications18

  1. doi request reprint Simultaneous determination of natural-abundance δ15N values and quantities of individual amino acids in proteins from milk of lactating women and from infant hair using gas chromatography/isotope ratio mass spectrometry
    Illa Tea
    Elucidation of Biosynthesis by Isotopic Spectrometry Group, CEISAM, LUNAM Université, University of Nantes CNRS UMR6230, 2 rue de la Houssiniere, BP 92208, F 44322 Nantes, France
    Rapid Commun Mass Spectrom 27:1345-53. 2013
    ..This report shows how this can be achieved in a single chromatographic run for protein amino acids using an isotope ratio mass spectrometer...
  2. pmc 1H-NMR-based metabolic profiling of maternal and umbilical cord blood indicates altered materno-foetal nutrient exchange in preterm infants
    Illa Tea
    Elucidation of Biosynthesis by Isotopic Spectrometry Group, Unit for Interdisciplinary Chemistry, Synthesis Analysis Modelling CEISAM, University of Nantes CNRS UMR 6230, Nantes, France
    PLoS ONE 7:e29947. 2012
    ..We have used (1)H nuclear magnetic resonance (NMR) spectroscopy to probe the metabolic adaptations associated with premature birth...
  3. doi request reprint Determination of the natural abundance δ15N of taurine by gas chromatography-isotope ratio measurement mass spectrometry
    Illa Tea
    Elucidation of Biosynthesis by Isotopic Spectrometry Group, Unit for Interdisciplinary Chemistry Synthesis Analysis Modelling CEISAM, University of Nantes CNRS UMR6230, 2 rue de la Houssiniere, BP 92208, F 44322 Nantes, France
    Rapid Commun Mass Spectrom 24:3380-6. 2010
    ..The optimized method enables the determination of the natural abundance δ(15)N values of taurine over the concentration range 1.5-7.84 µmol.mL(-1) in samples of biological origin...
  4. doi request reprint In situ NMR spectroelectrochemistry for the structure elucidation of unstable intermediate metabolites
    Ugo Bussy
    CNRS, Chimie et Interdisciplinarite Synthese, Analyse et Modélisation CEISAM, UMR 6230, LUNAM Université de Nantes, 2 rue de la Houssiniere, BP 92208, 44322, Nantes Cedex 3, France
    Anal Bioanal Chem 405:5817-24. 2013
    ..We demonstrated that in situ NMR spectroelectrochemistry constitutes a fast way for monitoring unstable quinone imines and elucidating their chemical structures. ..
  5. ncbi request reprint Determination of the concentration of nitrogenous bio-organic compounds using an isotope ratio mass spectrometer operating in continuous flow mode
    Illa Tea
    Elucidation of Biosynthesis by Isotopic Spectrometry Group, Unit for Interdisciplinary Chemistry Synthesis Analysis Modelling CEISAM, University of Nantes CNRS UMR6230, Nantes, France
    Anal Bioanal Chem 401:1263-71. 2011
    ..In addition, it is demonstrated that over a definable range, the δ(15)N (‰) value is independent of the quantity of analyte introduced, confirming the validity of this method...
  6. pmc Cord blood glutathione depletion in preterm infants: correlation with maternal cysteine depletion
    Alice Kuster
    UMR Physiologie des Adaptations Nutritionnelles, INRA, Universite de Nantes, Nantes, France
    PLoS ONE 6:e27626. 2011
    ..Depletion of blood glutathione (GSH), a key antioxidant, is known to occur in preterm infants...
  7. doi request reprint Acebutolol and alprenolol metabolism predictions: comparative study of electrochemical and cytochrome P450-catalyzed reactions using liquid chromatography coupled to high-resolution mass spectrometry
    Ugo Bussy
    LUNAM Université de Nantes, CNRS, Chimie et Interdisciplinarite Synthese, Analyse et Modélisation CEISAM, UMR 6230, 2 rue de la Houssiniere, BP 92208, 44322, Nantes Cedex 3, France
    Anal Bioanal Chem 405:6077-85. 2013
    ..The present study highlights the potential and limitation of coupling of electrochemistry-liquid chromatography-high-resolution mass spectrometry for the study of phase I and phase II reactions of acebutolol and alprenolol. ..
  8. doi request reprint New practical tools for the implementation and use of ultrafast 2D NMR experiments
    Meerakhan Pathan
    CNRS, Chimie et Interdisciplinarite Synthese, Analyse, Modelisation CEISAM, UMR 6230, Faculte des Sciences, Universite de Nantes, BP 92208, 2 rue de la Houssiniere, F 44322 Nantes Cedex 03, France
    Magn Reson Chem 51:168-75. 2013
    ..We believe that this tool will eliminate much of the technical difficulties related to UF 2D NMR and will make the technique accessible to a wider audience of organic and analytical chemists...
  9. doi request reprint Maternal and cord blood LC-HRMS metabolomics reveal alterations in energy and polyamine metabolism, and oxidative stress in very-low birth weight infants
    Marie Cécile Alexandre-Gouabau
    UMR Physiologie des Adaptations Nutritionnelles, INRA, IMAD, CRNH, Nantes, France
    J Proteome Res 12:2764-78. 2013
    ..Our metabolomics study allowed the identification of alterations in fetal energy, antioxidant defense, and polyamines and purines flux as a signature of premature birth...
  10. doi request reprint Human baby hair amino acid natural abundance 15N-isotope values are not related to the 15N-isotope values of amino acids in mother's breast milk protein
    Katarzyna M Romek
    Elucidation of Biosynthesis by Isotopic Spectrometry Group, CEISAM, University of Nantes CNRS UMR6230, 2 rue de la Houssiniere, BP 92208, 44322, Nantes, France
    Amino Acids 45:1365-72. 2013
    ..Rather, it would appear that each pool-mother and infant-turns over independently, and that fractionation in infant N-metabolism even in the first month of life dominates over the nutrient N-content. ..
  11. ncbi request reprint Understanding the degradation of electrochemically-generated reactive drug metabolites by quantitative NMR
    Ugo Bussy
    LUNAM Université de Nantes, CNRS, Chimie et Interdisciplinarite Synthese, Analyse et Modélisation CEISAM, UMR 6230, 2 rue de la Houssiniere, BP 92208, F 44322 Nantes Cedex 3, France Electronic address
    Talanta 116:554-8. 2013
    ..The combination of electrochemistry with quantitative NMR is thus presented as a relevant method for elucidating the degradation of reactive metabolites and may be considered a valuable complementary tool to EC-MS. ..
  12. doi request reprint Determination of the natural abundance delta15N of nortropane alkaloids by gas chromatography-isotope ratio mass spectrometry of their ethylcarbamate esters
    Katarzyna Kosieradzka
    Elucidation of Biosynthesis by Isotopic Spectrometry Group, Unit for Interdisciplinary Chemistry Synthesis Analysis Modelling CEISAM, University of Nantes CNRS UMR6230, 2, Rue de la Houssiniere, 44322 Nantes, France
    Anal Bioanal Chem 396:1405-14. 2010
    ..The precision and reproducibility are shown sufficient to allow the evolution of the delta(15)N values to be followed during the fermentation...
  13. ncbi request reprint Determination of 13C isotopic enrichment of glutathione and glycine by gas chromatography/combustion/isotope ratio mass spectrometry after formation of the N- or N,S-ethoxycarbonyl methyl ester derivatives
    Illa Tea
    Laboratoire d Analyse Isotopique et Electrochimique des Métabolismes LAIEM, UMR CNRS 6006, Universite de Nantes, 2 rue de la Houssiniere, BP 92208, F 44322 Nantes Cedex, France
    Rapid Commun Mass Spectrom 21:3245-52. 2007
    ..This approach provides a good tool for studying the turnover of GSH in vitro in infants, allowing both the use of minimal amounts of tracer and negligible perturbation of endogenous precursor pools...
  14. ncbi request reprint Reference and normalization methods: essential tools for the intercomparison of NMR spectra
    Patrick Giraudeau
    EBSI team, Chimie et Interdisciplinarite Synthese, Analyse, Modelisation CEISAM, Universite de Nantes, CNRS, UMR 6230, LUNAM Université, B P 92208, 2 rue de la Houssiniere, F 44322 Nantes Cedex 03, France
    J Pharm Biomed Anal 93:3-16. 2014
    ..After defining the main concepts, the principle, the analytical performance and the main recent applications of each method are described, and a critical discussion is finally provided. ..
  15. doi request reprint Fast determination of absolute metabolite concentrations by spatially encoded 2D NMR: application to breast cancer cell extracts
    Adrien Le Guennec
    Universite de Nantes, CNRS, CEISAM UMR 6230, B P 92208, 2 rue de la Houssiniere, F 44322 Nantes Cedex 03, France
    Anal Chem 84:10831-7. 2012
    ..M3S COSY spectra of such extracts are recorded in 20 min and give access to the absolute concentration of 14 major metabolites, showing significant differences between cell lines...
  16. doi request reprint Phytochemicals isolated from leaves of Chromolaena odorata: impact on viability and clonogenicity of cancer cell lines
    Prevost Bi Koffi Kouamé
    Elucidation of Biosynthesis by Isotopic Spectrometry Group, CEISAM, University of Nantes CNRS UMR6230, Nantes, France
    Phytother Res 27:835-40. 2013
    ....
  17. doi request reprint Voltammetry coupled to mass spectrometry in the presence of isotope 18O labeled water for the prediction of oxidative transformation pathways of activated aromatic ethers: acebutolol
    Ugo Bussy
    LUNAM Université de Nantes, CNRS, Chimie et Interdisciplinarite Synthese, Analyse et Modélisation CEISAM, UMR 6230, Nantes, France
    Anal Chim Acta 762:39-46. 2013
    ..The electrochemical oxidation mechanism was then elucidated showing an O-dealkoxylation reaction. In addition, density functional theory (DFT) calculations fully support the experimental conclusions...
  18. ncbi request reprint A test to identify cyanide origin by isotope ratio mass spectrometry for forensic investigation
    Illa Tea
    University of Nantes, Interdisciplinary Chemistry Synthesis, Analysis, Modelling CEISAM, UMR 6230, CNRS, 2 rue de la Houssinère, BP 92208, 44322 Nantes, France
    Forensic Sci Int 217:168-73. 2012
    ..In some matrices, the (13)C analysis was interfered by co-precipitates. With carefully elaborated working protocol, determining the isotope ratio of N and C in cyanide by EA-IRMS is a promising method for forensic investigations...