Laurent Sulpice

Summary

Country: France

Publications

  1. doi request reprint Epithelial cell adhesion molecule is a prognosis marker for intrahepatic cholangiocarcinoma
    Laurent Sulpice
    Liver Metabolisms and Cancer, INSERM UMR991, Rennes, France Université de Rennes 1, Rennes, France Service de Chirurgie Hépatobiliaire et Digestive, CHU Rennes, Rennes, France Electronic address
    J Surg Res 192:117-23. 2014
  2. doi request reprint Biliary cirrhosis and sepsis are two risk factors of failure after surgical repair of major bile duct injury post-laparoscopic cholecystectomy
    L Sulpice
    Service de chirurgie hépatobiliaire et digestive, Hopital Pontchaillou, Centre Hospitalier Universitaire, Universite de Rennes 1, Rennes, France
    Langenbecks Arch Surg 399:601-8. 2014
  3. ncbi request reprint Pancreatic head cancer in patients with chronic pancreatitis
    Aude Merdrignac
    Service de chirurgie hépatobiliaire et digestive, Hopital Pontchaillou, Centre Hospitalier Universitaire, Universite de Rennes 1, Rennes, France INSERM UMR991, Foie, Métabolismes et Cancer, Universite de Rennes 1, Rennes, France
    Hepatobiliary Pancreat Dis Int 13:192-7. 2014
  4. doi request reprint Advanced age remains an achilles heel for liver resections
    Laurent Sulpice
    Service de chirurgie hépatobiliaire et digestive, Hopital Pontchaillou, Centre Hospitalier Universitaire de Rennes, Universite de Rennes 1, Rennes, France
    World J Surg 38:918-26. 2014
  5. doi request reprint Does an aberrant right hepatic artery really influence the short- and long-term results of a pancreaticoduodenectomy for malignant disease? A matched case-controlled study
    Laurent Sulpice
    Service de chirurgie hépatobiliaire et digestive, Hopital Pontchaillou, Centre Hospitalier Universitaire, Universite de Rennes 1, Rennes, France INSERM, UMR991, Foie, Métabolismes et Cancer, Universite de Rennes 1, Rennes, France Electronic address
    J Surg Res 185:620-5. 2013
  6. doi request reprint Intrahepatic cholangiocarcinoma: impact of genetic hemochromatosis on outcome and overall survival after surgical resection
    Laurent Sulpice
    Service de chirurgie hépatobiliaire et digestive, Hopital Pontchaillou, Centre Hospitalier Universitaire, Universite de Rennes 1, Rennes, France
    J Surg Res 180:56-61. 2013
  7. doi request reprint Conservative surgical management of Boerhaave's syndrome: experience of two tertiary referral centers
    L Sulpice
    Service de chirurgie hépatobiliaire et digestive, CHU Rennes, Universite de Rennes 1, France
    Int J Surg 11:64-7. 2013
  8. pmc Dendritic cells are defective in breast cancer patients: a potential role for polyamine in this immunodeficiency
    Alban Gervais
    Groupe de Recherche en Therapeutique AntiCancereuse, UPRES 2261, Faculté de médecine de Rennes, Rennes, France
    Breast Cancer Res 7:R326-35. 2005
  9. doi request reprint Molecular profiling of stroma identifies osteopontin as an independent predictor of poor prognosis in intrahepatic cholangiocarcinoma
    Laurent Sulpice
    INSERM, UMR991, Liver Metabolisms and Cancer, Rennes, France Université de Rennes 1, Rennes, France CHU Rennes, Service de chirurgie hépatobiliaire et digestive, Rennes, France
    Hepatology 58:1992-2000. 2013
  10. doi request reprint Impact of age over 75 years on outcomes after pancreaticoduodenectomy
    Laurent Sulpice
    Service de chirurgie hépatobiliaire et digestive, Hopital Pontchaillou, Centre Hospitalier Universitaire, Universite de Rennes 1, Rennes, France
    J Surg Res 178:181-7. 2012

Collaborators

  • Karim Boudjema
  • Michel Rayar
  • Jean François Bretagne
  • Jean Luc Raoul
  • Bruno Turlin
  • B Meunier
  • Sylvain Manfredi
  • S Garnier
  • Philippe Compagnon
  • Eveline Boucher
  • Damien Bergeat
  • Etienne Garin
  • Julien Edeline
  • Tanguy Rohou
  • Giovanni Battista Levi Sandri
  • Aude Merdrignac
  • Habiba Mesbah
  • Bernard Faber
  • Antoine Guillaud
  • Marc Pracht
  • Sabrina Layec
  • Alban Gervais
  • Bruno Clement
  • Nicolas Icard
  • Sophie Laffont
  • Aude Merdignac
  • Yan Rolland
  • Mathias Breton
  • Laurence Lenoir
  • Ayman Zamreek
  • Elise Bosquet
  • Emmanuel Quehen
  • Sulpice Laurent
  • Claire Pery
  • Boris Campillo
  • Anne Lourdais
  • Odile Audrain
  • Guillaume Le Roux
  • Pierre Nicolas D'Halluin
  • Mael Pagenault
  • Jean Jacques Patard
  • Jean Leveque
  • Veronique Catros-Quemener
  • Francoise Bouet-Toussaint
  • Thierry Lesimple
  • Noelle Genetet
  • Florence Burtin

Detail Information

Publications20

  1. doi request reprint Epithelial cell adhesion molecule is a prognosis marker for intrahepatic cholangiocarcinoma
    Laurent Sulpice
    Liver Metabolisms and Cancer, INSERM UMR991, Rennes, France Université de Rennes 1, Rennes, France Service de Chirurgie Hépatobiliaire et Digestive, CHU Rennes, Rennes, France Electronic address
    J Surg Res 192:117-23. 2014
    ..The most upregulated genes included epithelial cell adhesion molecule (EpCAM), a biomarker of cancer stem cells (CSC). We hypothesized that CSC biomarkers could predict recurrence of resected ICC...
  2. doi request reprint Biliary cirrhosis and sepsis are two risk factors of failure after surgical repair of major bile duct injury post-laparoscopic cholecystectomy
    L Sulpice
    Service de chirurgie hépatobiliaire et digestive, Hopital Pontchaillou, Centre Hospitalier Universitaire, Universite de Rennes 1, Rennes, France
    Langenbecks Arch Surg 399:601-8. 2014
    ..3 to 0.6 % and is associated with a significant mortality rate. The aim of this study was to retrospectively analyze the factors likely to influence the long-term results of surgical repair for MBDI occurring after LC...
  3. ncbi request reprint Pancreatic head cancer in patients with chronic pancreatitis
    Aude Merdrignac
    Service de chirurgie hépatobiliaire et digestive, Hopital Pontchaillou, Centre Hospitalier Universitaire, Universite de Rennes 1, Rennes, France INSERM UMR991, Foie, Métabolismes et Cancer, Universite de Rennes 1, Rennes, France
    Hepatobiliary Pancreat Dis Int 13:192-7. 2014
    ..The aim of this study was to evaluate the relevance between this indication of PD and the definitive pathological results...
  4. doi request reprint Advanced age remains an achilles heel for liver resections
    Laurent Sulpice
    Service de chirurgie hépatobiliaire et digestive, Hopital Pontchaillou, Centre Hospitalier Universitaire de Rennes, Universite de Rennes 1, Rennes, France
    World J Surg 38:918-26. 2014
    ..This basic question is especially true for liver resection (LR). The aim of this study was to evaluate the operative risks of LR in the elderly...
  5. doi request reprint Does an aberrant right hepatic artery really influence the short- and long-term results of a pancreaticoduodenectomy for malignant disease? A matched case-controlled study
    Laurent Sulpice
    Service de chirurgie hépatobiliaire et digestive, Hopital Pontchaillou, Centre Hospitalier Universitaire, Universite de Rennes 1, Rennes, France INSERM, UMR991, Foie, Métabolismes et Cancer, Universite de Rennes 1, Rennes, France Electronic address
    J Surg Res 185:620-5. 2013
    ..The risk associated with ARHA during pancreaticoduodenectomy (PD) continues to be debated. The aim of this study was to compare the clinical outcomes and survival after PD with ARHA against a matched cohort of patients without ARHA...
  6. doi request reprint Intrahepatic cholangiocarcinoma: impact of genetic hemochromatosis on outcome and overall survival after surgical resection
    Laurent Sulpice
    Service de chirurgie hépatobiliaire et digestive, Hopital Pontchaillou, Centre Hospitalier Universitaire, Universite de Rennes 1, Rennes, France
    J Surg Res 180:56-61. 2013
    ..The influence of genetic hemochromatosis (GH) on outcomes following surgical resections for intrahepatic cholangiocarcinoma (ICC) has not been evaluated...
  7. doi request reprint Conservative surgical management of Boerhaave's syndrome: experience of two tertiary referral centers
    L Sulpice
    Service de chirurgie hépatobiliaire et digestive, CHU Rennes, Universite de Rennes 1, France
    Int J Surg 11:64-7. 2013
    ..But diagnosis can be difficult, delaying appropriate management. The purpose of the present study was to evaluate outcome of conservative surgery for primary or T-tube repair performed in two tertiary referral centers...
  8. pmc Dendritic cells are defective in breast cancer patients: a potential role for polyamine in this immunodeficiency
    Alban Gervais
    Groupe de Recherche en Therapeutique AntiCancereuse, UPRES 2261, Faculté de médecine de Rennes, Rennes, France
    Breast Cancer Res 7:R326-35. 2005
    ....
  9. doi request reprint Molecular profiling of stroma identifies osteopontin as an independent predictor of poor prognosis in intrahepatic cholangiocarcinoma
    Laurent Sulpice
    INSERM, UMR991, Liver Metabolisms and Cancer, Rennes, France Université de Rennes 1, Rennes, France CHU Rennes, Service de chirurgie hépatobiliaire et digestive, Rennes, France
    Hepatology 58:1992-2000. 2013
    ..More important, multivariate analysis demonstrated that the stromal expression of osteopontin was an independent prognostic marker for overall and disease-free survival...
  10. doi request reprint Impact of age over 75 years on outcomes after pancreaticoduodenectomy
    Laurent Sulpice
    Service de chirurgie hépatobiliaire et digestive, Hopital Pontchaillou, Centre Hospitalier Universitaire, Universite de Rennes 1, Rennes, France
    J Surg Res 178:181-7. 2012
    ..The aim of our study was to assess the incidence of death and postoperative complications following PD and identify the risk factors in patients >75 y...
  11. pmc Incidence and predictive factors of clinically relevant bile leakage in the modern era of liver resections
    Antoine Guillaud
    Service de chirurgie hépatobiliaire et digestive, Universite de Rennes, Rennes, France
    HPB (Oxford) 15:224-9. 2013
    ..To evaluate the incidence, the impact on survival and the predictive factors of bile leakage (BL) in a recent large monocentric series of liver resections performed in a referral tertiary care centre...
  12. doi request reprint Extended liver resections for intrahepatic cholangiocarcinoma: Friend or foe?
    Damien Bergeat
    Service de chirurgie hépatobiliaire et digestive, Hopital Pontchaillou, Centre Hospitalier Université de Rennes 1, Rennes, France INSERM, UMR991, Foie, Métabolisme et Cancer, Universite de Rennes 1, Rennes, France
    Surgery 157:656-65. 2015
    ..The aims of the present study were to evaluate the morbidity and oncologic outcomes of ELR compared with other liver resections (LR) for ICC...
  13. doi request reprint Enteral nutrition reduces delayed gastric emptying after standard pancreaticoduodenectomy with child reconstruction
    Michel Rayar
    Service de chirurgie hépatobiliaire et digestive, Hopital Pontchaillou, Centre Hospitalier Universitaire, Universite de Rennes 1, Rennes, France
    J Gastrointest Surg 16:1004-11. 2012
    ..Our retrospective study aimed to evaluate the influence of enteral nutrition (EN) on DGE incidence after standard PD with antrectomy and Child reconstruction...
  14. doi request reprint Chemotherapy for inoperable advanced or metastatic cholangiocarcinoma: retrospective analysis of 78 cases in a single center over four years
    Marc Pracht
    Medical Oncology Unit, Comprehensive Cancer Center Eugène Marquis, Rennes, France
    Chemotherapy 58:134-41. 2012
    ..According to phase II and III trials, regimens combining 5-fluorouracil (5FU) or gemcitabine with a platinum salt have provided an overall response rate of 12-50% with a median overall survival of 5-16 months...
  15. doi request reprint A simple system to predict perihilar cholangiocarcinoma resectability
    Karim Boudjema
    Service de chirurgie hépatobiliaire et digestive, Centre Hospitalier Universitaire de Rennes, Universite de Rennes 1, Rennes, France
    J Gastrointest Surg 17:1247-56. 2013
    ..When the LLC is invaded, vascular invasion is frequent and radical resection might often be impossible without complex vascular reconstruction...
  16. doi request reprint Extrahepatic portal vein aneurysm
    Giovanni Battista Levi Sandri
    Service de chirurgie hépatobiliaire et digestive, Centre Hospitalier Universitaire de Rennes, Universite de Rennes 1, Rennes, France
    Ann Vasc Surg 28:1319.e5-7. 2014
    ..Early complication was treated with a radiologic approach. Six months after surgery, patient had no more symptoms. PVA management remains a surgical challenge for surgeon, for timing and type of treatment. ..
  17. doi request reprint An update on liver surgery for cholangiocarcinoma
    Karim Boudjema
    Service de chirurgie hépatobiliaire et digestive, Centre Hospitalier Universitaire de Rennes, Universite de Rennes 1, Rennes Cedex, France
    Updates Surg 66:93-100. 2014
    ..We discussed the site at which to perform hepatic optimization prior to surgery, and whether liver transplantation might affect cholangiocarcinoma treatment. ..
  18. doi request reprint Colorectal cancer with synchronous liver metastases: does global management at the same centre improve results?
    Bernard Faber
    Service de chirurgie hépatobiliaire et digestive, Hopital Pontchaillou, Centre Hospitalier Universitaire de Rennes, Universite de Rennes 1, 2, rue Henri Le Guilloux, 35033 Rennes Cedex 9, France
    Clin Res Hepatol Gastroenterol 37:56-63. 2013
    ..Synchronous liver metastases (SLM) occur in 20% of colorectal cancers (CRC). Resection of SLM and CLC can be undertaken at different centres (separate management, SM) or at the same centre (global management, GM)...
  19. doi request reprint Personalized Dosimetry with Intensification Using 90Y-Loaded Glass Microsphere Radioembolization Induces Prolonged Overall Survival in Hepatocellular Carcinoma Patients with Portal Vein Thrombosis
    Etienne Garin
    Department of Nuclear Medicine, Cancer Institute Eugène Marquis, Rennes, France University of Rennes 1, Rennes, France U 991, Liver Metabolism and Cancer, INSERM, Rennes, France
    J Nucl Med 56:339-46. 2015
    ....
  20. doi request reprint Removal of transanastomotic pancreatic stent tubes after pancreaticoduodenectomy: a new role for double-balloon enteroscopy
    Sabrina Layec
    Service des Maladies de l Appareil digestif, Centre Hospitalo Universitaire, Rennes, France
    Gastrointest Endosc 72:449-51. 2010
    ..The recent development of the double-balloon enteroscopy (DBE) system creates an opportunity to reach the biliary tract and the pancreatic duct in postsurgical conditions...