Jean Claude Stoclet

Summary

Country: France

Publications

  1. ncbi request reprint Vascular protection by dietary polyphenols
    Jean Claude Stoclet
    Pharmacologie et Physico chimie des Interactions Cellulaires et Moléculaires, UMR CNRS 7034, Faculte de Pharmacie, Universite Louis Pasteur de Strasbourg, B P 60024, 74 route du Rhin, F 67401 Illkirch, France
    Eur J Pharmacol 500:299-313. 2004
  2. ncbi request reprint S-nitrosating nitric oxide donors induce long-lasting inhibition of contraction in isolated arteries
    Jacicarlos L Alencar
    Universite Louis Pasteur, Faculte de Pharmacie, Pharmacologie and Physico Chimie, Unité Mixte Recherche Centre National de la Recherche Scientifique, Illkirch, France
    J Pharmacol Exp Ther 307:152-9. 2003
  3. ncbi request reprint Inhibition of arterial contraction by dinitrosyl-iron complexes: critical role of the thiol ligand in determining rate of nitric oxide (NO) release and formation of releasable NO stores by S-nitrosation
    Jacicarlos L Alencar
    Faculte de Pharmacie, Pharmacologie and Physico Chimie, UMR CNRS 7034, Universite Louis Pasteur, 67401 Illkirch, France
    Biochem Pharmacol 66:2365-74. 2003
  4. ncbi request reprint Red wine polyphenolic compounds inhibit vascular endothelial growth factor expression in vascular smooth muscle cells by preventing the activation of the p38 mitogen-activated protein kinase pathway
    Min Ho Oak
    Pharmacologie et Physico chimie des Interactions Cellulaires et Moléculaires, UMR CNRS 7034, Universite Louis Pasteur de Strasbourg, Illkirch, France
    Arterioscler Thromb Vasc Biol 23:1001-7. 2003
  5. ncbi request reprint Role of S-nitrosation of cysteine residues in long-lasting inhibitory effect of nitric oxide on arterial tone
    Jacicarlos L Alencar
    Faculte de Pharmacie, Pharmacologie and Physico Chimie, Universite Louis Pasteur, Centre National de la Recherche Scientifique Unité Mixte Recherche 7034, 67401 Illkirch, France
    Mol Pharmacol 63:1148-58. 2003
  6. ncbi request reprint Heterogeneity of endothelium-dependent vasorelaxation in conductance and resistance arteries from Lyon normotensive and hypertensive rats
    Maria Regina Freitas
    Laboratoire de Pharmacologie et Physico Chimie des Interactions Cellulaires et Moléculaires, Universite Louis Pasteur de Strasbourg, Faculte de Pharmacie, Illkirch, France
    J Hypertens 21:1505-12. 2003
  7. ncbi request reprint Role of the adventitia in the cyclic GMP-mediated relaxant effect of N-hydroxy-L-arginine in rat aorta
    Petra Beranova
    Pharmacologie et Physico Chimie, UMR CNRS 7034, Universite Louis Pasteur de Strasbourg, France
    J Vasc Res 42:331-6. 2005
  8. ncbi request reprint Red wine polyphenols cause endothelium-dependent EDHF-mediated relaxations in porcine coronary arteries via a redox-sensitive mechanism
    Mamadou Ndiaye
    Pharmacologie et Physico chimie des Interactions Cellulaires et Moléculaires, UMR CNRS 7034, Faculte de Pharmacie, Universite Louis Pasteur de Strasbourg, Strasbourg, France
    Biochem Biophys Res Commun 310:371-7. 2003
  9. ncbi request reprint Nitric oxide transport and storage in the cardiovascular system
    Bernard Muller
    Universite Louis Pasteur, CNRS UMR 7034, Faculte de Pharmacie, BP 24, 67401 Illkirch Cedex, France
    Ann N Y Acad Sci 962:131-9. 2002
  10. ncbi request reprint [Human blood vessels created with tissue engineering]
    Jean Claude Stoclet
    Laboratoire de pharmacologie et physicochimie des interactions cellulaires et moléculaires, UMR CNRS 7034, Faculte de Pharmacie, BP 24, 74, route du Rhin, 67401 Illkirch, France
    Med Sci (Paris) 20:675-8. 2004

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Vascular protection by dietary polyphenols
    Jean Claude Stoclet
    Pharmacologie et Physico chimie des Interactions Cellulaires et Moléculaires, UMR CNRS 7034, Faculte de Pharmacie, Universite Louis Pasteur de Strasbourg, B P 60024, 74 route du Rhin, F 67401 Illkirch, France
    Eur J Pharmacol 500:299-313. 2004
    ....
  2. ncbi request reprint S-nitrosating nitric oxide donors induce long-lasting inhibition of contraction in isolated arteries
    Jacicarlos L Alencar
    Universite Louis Pasteur, Faculte de Pharmacie, Pharmacologie and Physico Chimie, Unité Mixte Recherche Centre National de la Recherche Scientifique, Illkirch, France
    J Pharmacol Exp Ther 307:152-9. 2003
    ..These differential effects of NO donors may be important for orientating their therapeutic indications...
  3. ncbi request reprint Inhibition of arterial contraction by dinitrosyl-iron complexes: critical role of the thiol ligand in determining rate of nitric oxide (NO) release and formation of releasable NO stores by S-nitrosation
    Jacicarlos L Alencar
    Faculte de Pharmacie, Pharmacologie and Physico Chimie, UMR CNRS 7034, Universite Louis Pasteur, 67401 Illkirch, France
    Biochem Pharmacol 66:2365-74. 2003
    ..Thus, the nature of the thiol ligand plays a critical role in determining the mechanisms and duration of the effect of LMW-DNIC in arteries...
  4. ncbi request reprint Red wine polyphenolic compounds inhibit vascular endothelial growth factor expression in vascular smooth muscle cells by preventing the activation of the p38 mitogen-activated protein kinase pathway
    Min Ho Oak
    Pharmacologie et Physico chimie des Interactions Cellulaires et Moléculaires, UMR CNRS 7034, Universite Louis Pasteur de Strasbourg, Illkirch, France
    Arterioscler Thromb Vasc Biol 23:1001-7. 2003
    ..This study examines whether red wine polyphenolic compounds (RWPCs) affect vascular endothelial growth factor (VEGF) expression, a major angiogenic and proatherosclerotic factor in vascular smooth muscle cells (VSMCs)...
  5. ncbi request reprint Role of S-nitrosation of cysteine residues in long-lasting inhibitory effect of nitric oxide on arterial tone
    Jacicarlos L Alencar
    Faculte de Pharmacie, Pharmacologie and Physico Chimie, Universite Louis Pasteur, Centre National de la Recherche Scientifique Unité Mixte Recherche 7034, 67401 Illkirch, France
    Mol Pharmacol 63:1148-58. 2003
    ..They suggest that S-nitrosation of tissue thiols is a mechanism of formation of local NO stores from which biologically active NO can subsequently be released...
  6. ncbi request reprint Heterogeneity of endothelium-dependent vasorelaxation in conductance and resistance arteries from Lyon normotensive and hypertensive rats
    Maria Regina Freitas
    Laboratoire de Pharmacologie et Physico Chimie des Interactions Cellulaires et Moléculaires, Universite Louis Pasteur de Strasbourg, Faculte de Pharmacie, Illkirch, France
    J Hypertens 21:1505-12. 2003
    ..Differences in endothelial function between the two strains were evaluated...
  7. ncbi request reprint Role of the adventitia in the cyclic GMP-mediated relaxant effect of N-hydroxy-L-arginine in rat aorta
    Petra Beranova
    Pharmacologie et Physico Chimie, UMR CNRS 7034, Universite Louis Pasteur de Strasbourg, France
    J Vasc Res 42:331-6. 2005
    ..They suggest that NO or an NO-related compound formed from L-NOHA in the adventitia may produce paracrine effects...
  8. ncbi request reprint Red wine polyphenols cause endothelium-dependent EDHF-mediated relaxations in porcine coronary arteries via a redox-sensitive mechanism
    Mamadou Ndiaye
    Pharmacologie et Physico chimie des Interactions Cellulaires et Moléculaires, UMR CNRS 7034, Faculte de Pharmacie, Universite Louis Pasteur de Strasbourg, Strasbourg, France
    Biochem Biophys Res Commun 310:371-7. 2003
    ..These findings demonstrate that RWPCs cause EDHF-mediated relaxations of coronary arteries, which are critically dependent on a redox-sensitive mechanism involving a flavin-dependent enzyme...
  9. ncbi request reprint Nitric oxide transport and storage in the cardiovascular system
    Bernard Muller
    Universite Louis Pasteur, CNRS UMR 7034, Faculte de Pharmacie, BP 24, 67401 Illkirch Cedex, France
    Ann N Y Acad Sci 962:131-9. 2002
    ..Thus, NO transport and storage mechanisms may be implicated in a variety of NO effects. The mechanisms of their formation and of NO release and their physiologic and pathophysiologic relevance deserve further investigations...
  10. ncbi request reprint [Human blood vessels created with tissue engineering]
    Jean Claude Stoclet
    Laboratoire de pharmacologie et physicochimie des interactions cellulaires et moléculaires, UMR CNRS 7034, Faculte de Pharmacie, BP 24, 74, route du Rhin, 67401 Illkirch, France
    Med Sci (Paris) 20:675-8. 2004
    ..These models may help to circumvent the limitations in the obtention and use of native human blood vessels for experimental purpose...
  11. ncbi request reprint Formation of releasable NO stores by S-nitrosoglutathione in arteries exhibiting tolerance to glyceryl-trinitrate
    Mamadou Sarr
    Pharmacologie and Physico Chimie, UMR CNRS 7034, Illkirch, France
    Eur J Pharmacol 513:119-23. 2005
    ..Formation of releasable NO stores is of potential interest to restore the protective effect of NO in organic nitrate-tolerant blood vessels...
  12. ncbi request reprint Nomega-hydroxy-L-arginine homologues and hydroxylamine as nitric oxide-dependent vasorelaxant agents
    Petra Beranova
    Pharmacology and Physico Chemistry, Centre National de la Recherche Scientifique and University Louis Pasteur of Strasbourg, Unité Mixte de Recherche 7034, Illkirch, France
    Eur J Pharmacol 516:260-7. 2005
    ....
  13. ncbi request reprint Involvement of NO in the endothelium-independent relaxing effects of N(omega)-hydroxy-L-arginine and other compounds bearing a C=NOH function in the rat aorta
    Petr Vetrovsky
    Pharmacology and Physico Chemistry, Centre National de la Recherche Scientifique Unité Mixte Recherche 7034 and University Louis Pasteur, Strasbourg, France
    J Pharmacol Exp Ther 303:823-30. 2002
    ..On one hand, L-NOHA and amidoximes may be useful tools for characterizing this pathway in blood vessels and, on the other, may offer a novel approach for treating vascular diseases with impaired endothelial NO activity...
  14. ncbi request reprint Targeted and persistent effects of NO mediated by S-nitrosation of tissue thiols in arteries with endothelial dysfunction
    Mamadou Sarr
    Pharmacologie and Physico Chimie, UMR CNRS 7175 LC1, BP 60024, F 67401 Illkirch
    Nitric Oxide 17:1-9. 2007
    ..Thus, formation of releasable NO stores by S-nitrosating agents allows targeted vasculoprotective effects of NO at sites of endothelial dysfunction...
  15. ncbi request reprint Relaxant effect of oxime derivatives in isolated rat aorta: role of nitric oxide (NO) formation in smooth muscle
    Karel Chalupsky
    UMR IRD U152, Faculte des sciences pharmaceutiques, Universite Paul Sabatier, 31062 Toulouse, France
    Biochem Pharmacol 67:1203-14. 2004
    ..Pathways of NO formation are likely distinct from NO synthases and from those responsible for GTN biotransformation. Oxime derivatives could be useful for NO delivery in arteries in which endothelial NO synthase activity is impaired...
  16. ncbi request reprint Cyclooxygenase-2 and inducible nitric oxide synthase in omental arteries harvested from patients with severe liver diseases: immuno-localization and influence on vascular tone
    Antonia Tabernero
    Laboratoire de pharmacologie et physicochimie des interactions cellulaires et moléculaires, CNRS UMR 7034, Illkirch, France
    Intensive Care Med 29:262-70. 2003
    ....