Philippe Gabriel Steg

Summary

Country: France

Publications

  1. pmc RUBY-1: a randomized, double-blind, placebo-controlled trial of the safety and tolerability of the novel oral factor Xa inhibitor darexaban (YM150) following acute coronary syndrome
    Ph Gabriel Steg
    INSERM U 698, Paris, France
    Eur Heart J 32:2541-54. 2011
  2. ncbi request reprint DECOPI (DEsobstruction COronaire en Post-Infarctus): a randomized multi-centre trial of occluded artery angioplasty after acute myocardial infarction
    Philippe Gabriel Steg
    Department of Cardiology, Hopital Bichat, 46 rue Henri Huchard, 75877 Paris Cedex 18, France
    Eur Heart J 25:2187-94. 2004
  3. ncbi request reprint Predischarge C-reactive protein and 1-year outcome after acute coronary syndromes
    Philippe Gabriel Steg
    Department of Cardiology, Hopital Bichat, Paris, France
    Am J Med 119:684-92. 2006
  4. ncbi request reprint Patterns of use and potential impact of early beta-blocker therapy in non-ST-elevation myocardial infarction with and without heart failure: the Global Registry of Acute Coronary Events
    Michael Emery
    The University of Michigan Cardiovascular Center, Ann Arbor, MI 48109 0477, USA
    Am Heart J 152:1015-21. 2006
  5. ncbi request reprint Autopsy prevalence of coronary atherosclerosis in patients with fatal stroke
    Fernando Gongora-Rivera
    Department of Neuropathology Raymond Escourolle, La Salpetriere Hospital, France
    Stroke 38:1203-10. 2007
  6. pmc Clinical characteristics, management, and control of permanent vs. nonpermanent atrial fibrillation: insights from the RealiseAF survey
    Jan Murin
    Department of Internal Medicine and Cardiology, Comenius University, Bratislava, Slovakia
    PLoS ONE 9:e86443. 2014
  7. ncbi request reprint Effect of cangrelor on periprocedural outcomes in percutaneous coronary interventions: a pooled analysis of patient-level data
    Philippe Gabriel Steg
    Universite Paris Diderot, Sorbonne Paris Cité, Paris, France Département Hospitalo Universitaire FIRE, Hopital Bichat, AP HP, INSERM U 698, Paris, France Electronic address
    Lancet 382:1981-92. 2013
  8. doi request reprint Design and methods of European Ambulance Acute Coronary Syndrome Angiography Trial (EUROMAX): an international randomized open-label ambulance trial of bivalirudin versus standard-of-care anticoagulation in patients with acute ST-segment-elevation myocard
    Philippe Gabriel Steg
    Universite Paris Diderot, Sorbonne Paris Cité, Paris, France INSERM U 698, Paris, France Département Hospitalo Universitaire FIRE, Hopital Bichat, Assistance Publique Hopitaux de Paris, Paris, France Electronic address
    Am Heart J 166:960-967.e6. 2013
  9. ncbi request reprint Stent thrombosis with ticagrelor versus clopidogrel in patients with acute coronary syndromes: an analysis from the prospective, randomized PLATO trial
    P Gabriel Steg
    INSERM unité 698, Hopital Bichat, 46 rue Henri Huchard, Paris, France
    Circulation 128:1055-65. 2013
  10. doi request reprint Anticoagulation with otamixaban and ischemic events in non-ST-segment elevation acute coronary syndromes: the TAO randomized clinical trial
    Philippe Gabriel Steg
    Universite Paris Diderot, Sorbonne Paris Cité, Paris, France
    JAMA 310:1145-55. 2013

Detail Information

Publications104 found, 100 shown here

  1. pmc RUBY-1: a randomized, double-blind, placebo-controlled trial of the safety and tolerability of the novel oral factor Xa inhibitor darexaban (YM150) following acute coronary syndrome
    Ph Gabriel Steg
    INSERM U 698, Paris, France
    Eur Heart J 32:2541-54. 2011
    ..To establish the safety, tolerability and most promising regimen of darexaban (YM150), a novel, oral, direct factor Xa inhibitor, for prevention of ischaemic events in acute coronary syndrome (ACS)...
  2. ncbi request reprint DECOPI (DEsobstruction COronaire en Post-Infarctus): a randomized multi-centre trial of occluded artery angioplasty after acute myocardial infarction
    Philippe Gabriel Steg
    Department of Cardiology, Hopital Bichat, 46 rue Henri Huchard, 75877 Paris Cedex 18, France
    Eur Heart J 25:2187-94. 2004
    ..To determine whether late recanalization of an occluded infarct artery after acute myocardial infarction is beneficial...
  3. ncbi request reprint Predischarge C-reactive protein and 1-year outcome after acute coronary syndromes
    Philippe Gabriel Steg
    Department of Cardiology, Hopital Bichat, Paris, France
    Am J Med 119:684-92. 2006
    ..To investigate the relationship between high-sensitivity C-reactive protein and cardiovascular events following acute coronary syndrome...
  4. ncbi request reprint Patterns of use and potential impact of early beta-blocker therapy in non-ST-elevation myocardial infarction with and without heart failure: the Global Registry of Acute Coronary Events
    Michael Emery
    The University of Michigan Cardiovascular Center, Ann Arbor, MI 48109 0477, USA
    Am Heart J 152:1015-21. 2006
    ..Early beta-blocker (BB) therapy improves outcomes in ST-segment elevation myocardial infarction; however, limited data are available on its early use and its impact in non-ST-segment elevation myocardial infarction (NSTEMI)...
  5. ncbi request reprint Autopsy prevalence of coronary atherosclerosis in patients with fatal stroke
    Fernando Gongora-Rivera
    Department of Neuropathology Raymond Escourolle, La Salpetriere Hospital, France
    Stroke 38:1203-10. 2007
    ..The objective of the study was to establish the prevalence of coronary atherosclerosis and MI after fatal stroke...
  6. pmc Clinical characteristics, management, and control of permanent vs. nonpermanent atrial fibrillation: insights from the RealiseAF survey
    Jan Murin
    Department of Internal Medicine and Cardiology, Comenius University, Bratislava, Slovakia
    PLoS ONE 9:e86443. 2014
    ....
  7. ncbi request reprint Effect of cangrelor on periprocedural outcomes in percutaneous coronary interventions: a pooled analysis of patient-level data
    Philippe Gabriel Steg
    Universite Paris Diderot, Sorbonne Paris Cité, Paris, France Département Hospitalo Universitaire FIRE, Hopital Bichat, AP HP, INSERM U 698, Paris, France Electronic address
    Lancet 382:1981-92. 2013
    ..We did a pooled analysis of data from three trials that assessed the effectiveness of cangrelor against either clopidogrel or placebo in PCI...
  8. doi request reprint Design and methods of European Ambulance Acute Coronary Syndrome Angiography Trial (EUROMAX): an international randomized open-label ambulance trial of bivalirudin versus standard-of-care anticoagulation in patients with acute ST-segment-elevation myocard
    Philippe Gabriel Steg
    Universite Paris Diderot, Sorbonne Paris Cité, Paris, France INSERM U 698, Paris, France Département Hospitalo Universitaire FIRE, Hopital Bichat, Assistance Publique Hopitaux de Paris, Paris, France Electronic address
    Am Heart J 166:960-967.e6. 2013
    ..In this prehospital setting, bivalirudin has not been compared with standard-of-care anticoagulation. In addition, it has not been tested in conjunction with the newer P2Y12 inhibitors prasugrel or ticagrelor...
  9. ncbi request reprint Stent thrombosis with ticagrelor versus clopidogrel in patients with acute coronary syndromes: an analysis from the prospective, randomized PLATO trial
    P Gabriel Steg
    INSERM unité 698, Hopital Bichat, 46 rue Henri Huchard, Paris, France
    Circulation 128:1055-65. 2013
    ..We aimed to describe the effects of ticagrelor versus clopidogrel on stent thrombosis in the Platelet Inhibition and Patient Outcomes (PLATO) trial...
  10. doi request reprint Anticoagulation with otamixaban and ischemic events in non-ST-segment elevation acute coronary syndromes: the TAO randomized clinical trial
    Philippe Gabriel Steg
    Universite Paris Diderot, Sorbonne Paris Cité, Paris, France
    JAMA 310:1145-55. 2013
    ..The optimal anticoagulant for patients with non-ST-segment elevation acute coronary syndromes (NSTE-ACS) managed with an invasive strategy remains controversial...
  11. doi request reprint A history of stroke/transient ischemic attack indicates high risks of cardiovascular event and hemorrhagic stroke in patients with coronary artery disease
    Gregory Ducrocq
    INSERM U 698 and Cardiology, Hopital Bichat, 46 rue Henri Huchard, 75877 Paris Cedex 18, France
    Circulation 127:730-8. 2013
    ..We aimed to further characterize the risk of ischemic and bleeding events associated with a history of stroke/TIA in patients with coronary artery disease...
  12. doi request reprint Design and rationale of the treatment of acute coronary syndromes with otamixaban trial: a double-blind triple-dummy 2-stage randomized trial comparing otamixaban to unfractionated heparin and eptifibatide in non-ST-segment elevation acute coronary syndro
    Philippe Gabriel Steg
    AP HP, Hopital Bichat, Paris, France
    Am Heart J 164:817-24.e13. 2012
    ....
  13. doi request reprint Symptoms, functional status and quality of life in patients with controlled and uncontrolled atrial fibrillation: data from the RealiseAF cross-sectional international registry
    P Gabriel Steg
    INSERM U, Paris, France
    Heart 98:195-201. 2012
    ..Rate control and rhythm control are accepted management strategies for atrial fibrillation (AF)...
  14. pmc Reporting of harm in randomized controlled trials evaluating stents for percutaneous coronary intervention
    Morgane Ethgen
    INSERM, U738, Paris, F 75018 France
    Trials 10:29. 2009
    ..The aim of this study was to assess the reporting of harm in randomized controlled trials evaluating stents for percutaneous coronary intervention...
  15. pmc Improving the management of non-ST elevation acute coronary syndromes: systematic evaluation of a quality improvement programme European QUality Improvement Programme for Acute Coronary Syndrome: the EQUIP-ACS project protocol and design
    Marcus D Flather
    Clinical Trials and Evaluation Unit, Royal Brompton Hospital, Sydney Street, SW7 6NP, UK
    Trials 11:5. 2010
    ....
  16. pmc Excess risk attributable to traditional cardiovascular risk factors in clinical practice settings across Europe - The EURIKA Study
    Eliseo Guallar
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    BMC Public Health 11:704. 2011
    ..The objective of this study was to estimate the excess risk attributable, firstly, to the presence of CVD risk factors and, secondly, to the lack of control of these risk factors in primary prevention care across Europe...
  17. pmc Rationale and methods of the European Study on Cardiovascular Risk Prevention and Management in Daily Practice (EURIKA)
    Fernando Rodriguez-Artalejo
    Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autonoma de Madrid, CIBER of Epidemiology and Public Health, Madrid 28029, Spain
    BMC Public Health 10:382. 2010
    ..It will also assess physicians' knowledge and attitudes about CVD prevention as well as the barriers impeding effective risk factor management in clinical practice...
  18. ncbi request reprint One-year cardiovascular event rates in outpatients with atherothrombosis
    Ph Gabriel Steg
    Departement de Cardiologie, Hopital Bichat Claude Bernard, Paris, France
    JAMA 297:1197-206. 2007
    ....
  19. doi request reprint Fondaparinux with UnfracTionated heparin dUring Revascularization in Acute coronary syndromes (FUTURA/OASIS 8): a randomized trial of intravenous unfractionated heparin during percutaneous coronary intervention in patients with non-ST-segment elevation ac
    Philippe Gabriel Steg
    INSERM U 698, Recherche Clinique en Athérothrombose, Universite Paris 7, Denis Diderot, Hopital Bichat, Assistance Publique Hopitaux de Paris, Paris, France
    Am Heart J 160:1029-34, 1034.e1. 2010
    ..There is uncertainty regarding the optimal adjunctive unfractionated heparin (UFH) regimen for percutaneous coronary intervention (PCI) in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS) treated with fondaparinux...
  20. doi request reprint Bleeding in acute coronary syndromes and percutaneous coronary interventions: position paper by the Working Group on Thrombosis of the European Society of Cardiology
    Philippe Gabriel Steg
    INSERM U 698, Université Paris Diderot and Centre Hospitalier Bichat, Assistance Publique Hopitaux de Paris, 46 rue Henri Huchard, 75018 Paris, France
    Eur Heart J 32:1854-64. 2011
    ..Finally, the research implications of bleeding (measuring and reporting bleeding in trials, the importance of bleeding as an outcome measure, and bleeding as a subject for future research) are also discussed...
  21. doi request reprint Atherothrombosis and the role of antiplatelet therapy
    Ph G Steg
    INSERM U 698, Universite Paris Diderot, Assistance Publique Hopitaux de Paris, Paris, France
    J Thromb Haemost 9:325-32. 2011
    ....
  22. ncbi request reprint Impact of in-hospital revascularization on survival in patients with non-ST-elevation acute coronary syndrome and congestive heart failure
    Philippe Gabriel Steg
    INSERM U 698, Recherche Clinique en Athérothrombose, Universite Paris VII, Centre Hospitalier Bichat Claude Bernard, 46 rue Henri Huchard, 75877 Paris, Cedex 18, France
    Circulation 118:1163-71. 2008
    ..The aims of this study were to describe the use of revascularization in non-ST-elevation acute coronary syndrome and CHF and to analyze its impact on survival...
  23. ncbi request reprint Ticagrelor versus clopidogrel in patients with ST-elevation acute coronary syndromes intended for reperfusion with primary percutaneous coronary intervention: A Platelet Inhibition and Patient Outcomes (PLATO) trial subgroup analysis
    Philippe Gabriel Steg
    INSERM U, Paris, France
    Circulation 122:2131-41. 2010
    ....
  24. doi request reprint Mortality following placement of drug-eluting and bare-metal stents for ST-segment elevation acute myocardial infarction in the Global Registry of Acute Coronary Events
    Ph Gabriel Steg
    INSERM U 698 Recherche Clinique en Athérothrombose, université Paris VII Denis Diderot, Assistance Publique Hopitaux de Paris, Centre Hospitalier Bichat Claude Bernard, 46 rue Henri Huchard, 75877 Paris Cedex 18, France
    Eur Heart J 30:321-9. 2009
    ..To assess mortality after drug-eluting stent (DES) or bare-metal stent (BMS) for ST-segment elevation myocardial infarction (STEMI)...
  25. ncbi request reprint A randomised trial of three counselling strategies for lifestyle changes in patients with hypercholesterolemia treated with ezetimibe on top of statin therapy (TWICE)
    Philippe Gabriel Steg
    INSERM U 698, université Paris VII Denis Diderot, Hopital Bichat Claude Bernard, AP HP, 46, rue Henri Huchard 75018 Paris, France
    Arch Cardiovasc Dis 101:723-35. 2008
    ..To compare the impact of three patient counselling strategies for lifestyle changes and to assess the safety and efficacy of ezetimibe on top of statin therapy in hypercholesterolemic high risk patients...
  26. doi request reprint Coronary artery disease and risk of major vascular events after cerebral infarction
    Pierre Amarenco
    INSERM U 698, Paris, France
    Stroke 44:1505-11. 2013
    ..The impact of asymptomatic coronary artery disease on the risk of major vascular events in patients with cerebral infarction is unknown...
  27. doi request reprint Clinical outcomes according to permanent discontinuation of clopidogrel or placebo in the CHARISMA trial
    Jean Philippe Collet
    Inserm unit 937, Institut de Cardiologie, Hopital Pitie Salpetriere, Assistance Publique Hopitaux de Paris, bureau 236, 47, Boulevard de l Hopital, 75013 Paris, France
    Arch Cardiovasc Dis 102:485-96. 2009
    ..Late discontinuation of clopidogrel after an acute coronary syndrome or stent placement may be associated with a clinical rebound effect...
  28. ncbi request reprint Microparticle-linked tissue factor activity and increased thrombin activity play a potential role in fibrinolysis failure in ST-segment elevation myocardial infarction
    Marie Genevieve Huisse
    Department of Haematology, AP HP, Hopital Bichat, Paris, France
    Thromb Haemost 101:734-40. 2009
    ..83 [14.83-40.43] mug/ml) than in controls (35.83 [27.9-43.94] mug/ml), p = 0.045. In conclusion, fibrinolysis failure in AMI is characterised by a higher procoagulant state associated with TF-MP and a lower plasmin generation...
  29. doi request reprint Universal reperfusion therapy can be implemented: lessons from 20 years of management of patients admitted within 6 hours of symptom onset with ST-segment elevation acute myocardial infarction
    Jean Michel Juliard
    Centre Hospitalier Bichat Claude Bernard, AP HP, 46, 75018 Paris, France
    Arch Cardiovasc Dis 102:259-67. 2009
    ..To describe longitudinal trends in patients' characteristics, management and hospital outcomes over 20 years of therapy for ST-segment elevation myocardial infarction (STEMI)...
  30. doi request reprint Overlap of diseases underlying ischemic stroke: the ASCOD phenotyping
    Gaia Sirimarco
    Paris Diderot University, Sorbonne Paris Cité, Paris, France
    Stroke 44:2427-33. 2013
    ..We used ASCOD to investigate the overlap of underlying vascular diseases and their prognostic implication...
  31. ncbi request reprint Five-year survival in patients with ST-segment-elevation myocardial infarction according to modalities of reperfusion therapy: the French Registry on Acute ST-Elevation and Non-ST-Elevation Myocardial Infarction (FAST-MI) 2005 Cohort
    Nicolas Danchin
    Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, Paris, France N D, E P INSERM U 970, Paris, France N D, E P Université Paris Descartes, Paris, France N D, E P Assistance Publique Hôpitaux de Paris, Hopital Bichat, Paris, France P G S INSERM U 698, Paris, France P G S Université Paris Diderot, Paris, France P G S Centre Hospitalier Régional Universitaire de Lille, Lille, France P G Hôpital Jean Minjoz, Besancon, France F S Université de Franche Comté, Besancon, France F S Centre Hospitalier d Annecy, Annecy, France L B Hôpital du Bocage, Dijon, France Y C Université de Bourgogne, Dijon, France Y C Clinique Pasteur, Toulouse, France J Fajadet Centre Hospitalier Régional de Metz Thionville, Metz, France K K Hôpital du Haut Levêque, Pessac, France P C Université Bordeaux Segalen, Bordeaux, France P C Hôpital Rangueil, Toulouse, Department of Embryology and Teratology
    Circulation 129:1629-36. 2014
    ..Although primary percutaneous coronary intervention (pPCI) is the preferred reperfusion method for ST-segment-elevation myocardial infarction, it remains difficult to implement in many areas, and fibrinolytic therapy is still widely used...
  32. doi request reprint Prevalence of coronary atherosclerosis in patients with cerebral infarction
    Pierre Amarenco
    INSERM U 698 and Paris Diderot University, Paris, France
    Stroke 42:22-9. 2011
    ....
  33. doi request reprint Carotid atherosclerosis and risk of subsequent coronary event in outpatients with atherothrombosis
    Gaia Sirimarco
    Department of Neurology and Stroke Center, AP HP, Bichat Claude Bernard Hospital, University of Paris Diderot, Sorbonne Paris Cité, Paris, France
    Stroke 44:373-9. 2013
    ..We examined the association among carotid atherosclerosis, history of atherothrombotic events, and risk of coronary events...
  34. ncbi request reprint Prevalence of embolic signals in acute coronary syndromes
    Elena Meseguer
    INSERM U 698 and Paris Diderot University, Bichat Hospital, Assistance Publique Hopitaux de Paris, Paris, France
    Stroke 41:261-6. 2010
    ..The purpose of this study was to assess the prevalence of embolic signals (ES) in acute coronary syndromes (ACS) and their association with stroke...
  35. doi request reprint Comparison of hospital mortality during ST-segment elevation myocardial infarction in the era of reperfusion therapy in women versus men and in older versus younger patients
    Jean Michel Juliard
    AP HP, Cardiology Department, Hopital Bichat, Universite Paris Diderot, Sorbonne Paris Cité, INSERM U 698, Paris, France
    Am J Cardiol 111:1708-13. 2013
    ....
  36. ncbi request reprint [Clinical characteristics, management and prognostic evolution of patients admitted within six hours of symptom onset with st-segment elevation acute myocardial infarction complicated by cardiogenic shock : twenty year monocentric study]
    Sami Marouene
    CHU Bichat Claude Bernard, Paris, France
    Tunis Med 90:715-9. 2012
    ..Cardiogenic shock is one of the most serious complications of the acute myocardial infarction. Advances in interventional cardiology and early reperfusion strategy improved its management...
  37. ncbi request reprint Impact of time to treatment on mortality after prehospital fibrinolysis or primary angioplasty: data from the CAPTIM randomized clinical trial
    Philippe Gabriel Steg
    Service de cardiologie, Hopital Bichat, 46 rue Henri Huchard, 75877 Paris Cedex 18, France
    Circulation 108:2851-6. 2003
    ....
  38. ncbi request reprint A transient ischaemic attack clinic with round-the-clock access (SOS-TIA): feasibility and effects
    Philippa C Lavallee
    Department of Neurology and Stroke Centre, Bichat Claude Bernard University Hospital, Denis Diderot University and Medical School Paris VII, Assistance Publique Hopitaux de Paris, Paris, France
    Lancet Neurol 6:953-60. 2007
    ..We evaluated the effects of rapid assessment of patients with TIA on clinical decision making, length of hospital stay, and subsequent stroke rates...
  39. doi request reprint Acute coronary angiographic findings in survivors of out-of-hospital cardiac arrest
    Zacharias Alexandros Anyfantakis
    Institut National de la Sante et de la Recherche Medicale, Universite Paris, Groupe Hospitalier Bichat Claude Bernard, Paris, France
    Am Heart J 157:312-8. 2009
    ..The objective of this study was to assess the prevalence of coronary lesions on emergency angiography in survivors of OHCA...
  40. ncbi request reprint Determinants and prognostic impact of heart failure complicating acute coronary syndromes: observations from the Global Registry of Acute Coronary Events (GRACE)
    Philippe Gabriel Steg
    Centre Hospitalier Universitaire Bichat Beaujon, Assistance Publique Hopitaux de Paris, France
    Circulation 109:494-9. 2004
    ..Few data are available on the impact of heart failure (HF) across all types of acute coronary syndromes (ACS)...
  41. ncbi request reprint Renin-angiotensin system antagonists and clinical outcomes in stable coronary artery disease without heart failure
    Emmanuel Sorbets
    Département Hospitalo Universitaire FIRE, Universite Paris Diderot, Sorbonne Paris Cité, Paris, France Inserm U 1148, Paris, France Hôpital Bichat, AP HP, Paris, France Hôpital Avicenne, AP HP, Bobigny, France Université Paris XIII, Bobigny, France
    Eur Heart J 35:1760-8. 2014
    ....
  42. ncbi request reprint Aortic arch atheroma in transient ischemic attack patients
    Celine Guidoux
    Department of Neurology and Stroke Centre, Bichat University Hospital, INSERM U 698 and Paris Diderot University, Paris, France Electronic address
    Atherosclerosis 231:124-8. 2013
    ..Aortic arch atheroma (AAA) is associated with vascular risk factors and with stroke risk. Its prevalence and prognosis remain to be defined in patients with transient ischemic attack (TIA)...
  43. ncbi request reprint External validity of clinical trials in acute myocardial infarction
    Philippe Gabriel Steg
    Department of Cardiology, Hopital Bichat, Paris, France
    Arch Intern Med 167:68-73. 2007
    ....
  44. ncbi request reprint Long-term clinical outcomes after rescue angioplasty are not different from those of successful thrombolysis for acute myocardial infarction
    Philippe Gabriel Steg
    Department of Cardiology, Hopital Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, 46 rue Henri Huchard, 75877 Paris Cedex 18, France
    Eur Heart J 26:1831-7. 2005
    ..This study aimed to compare long-term outcomes after successful thrombolysis vs. systematic attempted rescue PTCA...
  45. doi request reprint Association of changes in clinical characteristics and management with improvement in survival among patients with ST-elevation myocardial infarction
    Etienne Puymirat
    Assistance Publique Hopitaux de Paris AP HP, Hopital Europeen Georges Pompidou, Department of Cardiology, Universite Paris Descartes, and INSERM U 970, Paris, France
    JAMA 308:998-1006. 2012
    ..The contemporary decline in mortality reported in patients with ST-segment elevation myocardial infarction (STEMI) has been attributed mainly to improved use of reperfusion therapy...
  46. ncbi request reprint Influenza vaccination and cardiovascular risk in patients with recent TIA and stroke
    Philippa C Lavallee
    From INSERM U 698 and Paris Diderot University P C L, J L, P G S, P A, Sorbonne Paris Cité Department of Neurology and Stroke Centre P C L, J L, P A and Department of Cardiology P G S, AP HP, Bichat University Hospital, Paris, France NHLI Imperial College K M F, ICMS, Royal Brompton Hospital, London, UK Unidad de Tratamiento de Ataque Cerebrovascular P L, Clínica Alemana de Santiago Universidad del Desarrollo, Santiago, Chile Neurologische Klinik und Poliklinik H M, Universitat Bern, Inselspital, Switzerland
    Neurology 82:1905-13. 2014
    ..To determine whether current influenza vaccination is associated with reduced risk of major vascular events in patients with recent ischemic stroke or TIA of mainly atherothrombotic origin...
  47. ncbi request reprint Ischemia-modified albumin in acute stroke
    Halim Abboud
    Department of Neurology and Stroke Center, Bichat University Hospital, Denis Diderot University and Medical School, Paris, France
    Cerebrovasc Dis 23:216-20. 2007
    ..Ischemia-modified albumin (IMA)is a new biological marker of ischemia. Previous studies have found increased serum IMA levels after myocardial ischemia, but no study has investigated the possibility that stroke modifies IMA blood levels...
  48. doi request reprint Clinical events as a function of proton pump inhibitor use, clopidogrel use, and cytochrome P450 2C19 genotype in a large nationwide cohort of acute myocardial infarction: results from the French Registry of Acute ST-Elevation and Non-ST-Elevation Myocard
    Tabassome Simon
    Department of Pharmacology, Clinical Research Unit, APHP, St Antoine Hospital, UMPC Paris 06 University, 27 rue Chaligny, Paris, France
    Circulation 123:474-82. 2011
    ..This analysis compares treatment outcomes for patients in the French Registry of Acute ST-Elevation and Non-ST-Elevation Myocardial Infarction (FAST-MI) who did or did not receive clopidogrel and/or PPIs...
  49. doi request reprint Does lay media ranking of hospitals reflect lower mortality in treating acute myocardial infarction?
    Karine Chevreul
    AP HP, URC Eco and UPEC EA 4393, Paris, France
    Arch Cardiovasc Dis 105:489-98. 2012
    ..Ranking of hospitals by lay media has attracted widespread attention but may not accurately reflect quality. Acute myocardial infarction (AMI) mortality is a straightforward measure of clinical outcome frequently used by ranking algorithms...
  50. doi request reprint Screening for abdominal aortic aneurysm in coronary care unit patients with acute myocardial infarction using portable transthoracic echocardiography
    Caroline Cueff
    Cardiology Department, AP HP, Bichat Hospital, 46 rue Henri Huchard, 75018 Paris, France
    Eur Heart J Cardiovasc Imaging 13:574-8. 2012
    ..We aimed to evaluate the feasibility of AAA screening at bedside using a portable cardiac ultrasound (US) echo machine and to determine the prevalence of AAA in population with AMI...
  51. ncbi request reprint Gender differences in hospital mortality and use of percutaneous coronary intervention in acute myocardial infarction: microsimulation analysis of the 1999 nationwide French hospitals database
    Carine Milcent
    PSE Paris Jourdan Sciences Economiques L Ecole des Hautes Etudes en Sciences Sociales, Centre National de la Recherche Scientifique, Paris, France
    Circulation 115:833-9. 2007
    ..This difference has been ascribed to their older age, more frequent comorbidities, and less frequent use of revascularization. The aim of this study is to assess these factors in relation to excess mortality in women...
  52. pmc Risk score to predict serious bleeding in stable outpatients with or at risk of atherothrombosis
    Gregory Ducrocq
    INSERM U 698 Recherche Clinique en Athérothrombose, Department of Cardiology, Centre Hospitalier Universitaire Bichat Claude Bernard, 46 rue Henri Huchard, Paris Cedex, France
    Eur Heart J 31:1257-65. 2010
    ..To develop a risk score to quantify bleeding risk in outpatients with or at risk of atherothrombosis...
  53. pmc Delphi-consensus weights for ischemic and bleeding events to be included in a composite outcome for RCTs in thrombosis prevention
    Agnes Dechartres
    UMR S 738, INSERM, Paris, France
    PLoS ONE 6:e18461. 2011
    ..To weight ischemic and bleeding events according to their severity to be used in a composite outcome in RCTs in the field of thrombosis prevention...
  54. ncbi request reprint Rapid desensitization procedure for patients with aspirin hypersensitivity undergoing coronary stenting
    Stephane Silberman
    Department of Cardiology, Hopital Bichat, Paris, France
    Am J Cardiol 95:509-10. 2005
    ..No late allergic reactions or adverse cardiac events were seen after a mean follow-up of 14 months. A rapid challenge-desensitization procedure may allow introduction of aspirin at therapeutic doses within a few hours...
  55. ncbi request reprint Baseline characteristics, management practices, and in-hospital outcomes of patients hospitalized with acute coronary syndromes in the Global Registry of Acute Coronary Events (GRACE)
    Philippe Gabriel Steg
    Hopital Bichat, Paris, France
    Am J Cardiol 90:358-63. 2002
    ..0001), and recurrent angina with ST-segment changes occurred before discharge in 10%, 10%, and 9% of patients, respectively (p = 0.2644). GRACE provides a detailed and comprehensive global description of the spectrum of patients with ACS...
  56. ncbi request reprint Demographics, socio-economic characteristics, and risk factor prevalence in patients with non-cardioembolic ischaemic stroke in low- and middle-income countries: the OPTIC registry
    Halim Abboud
    Hotel Dieu de France, Saint Joseph University, Beirut, Lebanon Department of Neurology and Stroke Center, Bichat University Hospital, Paris, France
    Int J Stroke 8:4-13. 2013
    ..We sought to describe the characteristics and management of patients with an ischaemic stroke and recent transient ischaemic attack or minor ischaemic strokes in low- or middle-income countries...
  57. doi request reprint Stroke and outcomes in patients with acute type A aortic dissection
    Eduardo Bossone
    Department of Cardiology, University of Salerno, Salerno, Italy E B Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI D C C, E K R, D G M, K A E Abbott Northwestern Hospital, Minneapolis Heart Institute, Minneapolis, MN K M H Department of Cardiovascular Medicine, University of Tokyo, Tokyo, Japan T S Department of Interventional Cardiology, San Salvatore Hospital, Pesaro, Italy R F Department of Cardiac Sciences, University of Calgary, Calgary, Canada S H Department of Cardiothoracic Surgery, University of Vienna, Vienna, Austria M P E Division of Medical Genetics, University of Pennsylvania, Philadelphia, PA R E P Department of Cardiology, Hopital Bichat, Paris, France P G S Division of Cardiovascular Surgery, Mayo Clinic, Rochester, MN K G Servei de Cardiologia, Hospital General Universitari Vall d Hebron, Barcelona, Spain A E Thoracic Aortic Center, Massachusetts General Hospital, Boston, MA E M I and Department of Internal Medicine, University of Rostock, Rostock, Germany C A N
    Circulation 128:S175-9. 2013
    ..Stroke is a highly dreaded complication of type A acute aortic dissection (TAAAD). However, little data exist on its incidence and association with prognosis...
  58. ncbi request reprint Prevalence and determinants of subdiaphragmatic visceral infarction in patients with fatal stroke
    Halim Abboud
    Assistance Publique Hopitaux de Paris, Paris, France
    Stroke 38:1442-6. 2007
    ..We therefore investigated the prevalence of SDVI in subjects who died from stroke. We also evaluated the yield of SDVI diagnosis for stroke subtyping...
  59. doi request reprint In vitro and in vivo evidence for the role of elastase shedding of CD163 in human atherothrombosis
    Juan Antonio Moreno
    INSERM U, Paris, France
    Eur Heart J 33:252-63. 2012
    ..We analysed the relationship between CD163 solubilization and elastase in vitro, in macrophage culture, ex vivo in human atherosclerotic plaque samples, and in vivo, in plasma of patients with coronary artery disease...
  60. doi request reprint Comparison of clinical presentations and outcomes between patients with TGFBR2 and FBN1 mutations in Marfan syndrome and related disorders
    David Attias
    Centre de référence pour le syndrome de Marfan et apparentés, Hopital Bichat, Paris, France
    Circulation 120:2541-9. 2009
    ..TGFBR2 mutations were recognized recently among patients with a Marfan-like phenotype. The associated clinical and prognostic spectra remain unclear...
  61. ncbi request reprint Immediate vs delayed intervention for acute coronary syndromes: a randomized clinical trial
    Gilles Montalescot
    Institut de Cardiologie, Bureau 2 236, Centre Hospitalier Universitaire Pitie Salpetriere, 47 Boulevard de l Hopital, 75013 Paris, France
    JAMA 302:947-54. 2009
    ..International guidelines recommend an early invasive strategy for patients with high-risk acute coronary syndromes without ST-segment elevation, but the optimal timing of intervention is uncertain...
  62. doi request reprint Comparison of thrombolysis followed by broad use of percutaneous coronary intervention with primary percutaneous coronary intervention for ST-segment-elevation acute myocardial infarction: data from the french registry on acute ST-elevation myocardial inf
    Nicolas Danchin
    Division of Coronary Artery Disease and Intensive Cardiac Care, Hopital Europeen Georges Pompidou, Assistance Publique des Hôpitaux de Paris and Faculté René Descartes, Universite Paris 5, 20 rue Leblanc, 75015 Paris, France
    Circulation 118:268-76. 2008
    ....
  63. doi request reprint Effects of adherence to guidelines for the control of major cardiovascular risk factors on outcomes in the REduction of Atherothrombosis for Continued Health (REACH) Registry Europe
    Patrice P Cacoub
    AP HP Service de Médecine Interne, Groupe Hospitalier La Pitié Salpêtrière, 47 83, Boulevard de l Hopital, 75013 Paris, France
    Heart 97:660-7. 2011
    ..To examine the impact of cardiovascular risk factor control on 3-year cardiovascular event rates in patients with stable symptomatic atherothrombotic disease in Europe...
  64. doi request reprint Stroke is a coronary heart disease risk equivalent: implications for future clinical trials in secondary stroke prevention
    Pierre Amarenco
    INSERM U 698 and Denis Diderot University Paris VII, France
    Eur Heart J 29:1605-7. 2008
  65. doi request reprint Impact of anticoagulation levels on outcomes in patients undergoing elective percutaneous coronary intervention: insights from the STEEPLE trial
    Gilles Montalescot
    Institut de Cardiologie AP HP and INSERM Unit no 856, Centre Hospitalier Universitaire Pitie Salpetriere, Paris, France
    Eur Heart J 29:462-71. 2008
    ..To determine the relationship between anticoagulation levels during percutaneous coronary intervention, and ischaemic events and bleeding...
  66. ncbi request reprint Enhanced shear-induced platelet aggregation in patients who experience subacute stent thrombosis: a case-control study
    Nadine Ajzenberg
    Hématologie et Immunologie, Hopital Bichat, Paris, France
    J Am Coll Cardiol 45:1753-6. 2005
    ..The goal of this study was to identify differences in shear-induced platelet aggregation (SIPA) between patients who did or did not experience subacute stent thrombosis (SAT)...
  67. ncbi request reprint A randomized comparison of high clopidogrel loading doses in patients with non-ST-segment elevation acute coronary syndromes: the ALBION (Assessment of the Best Loading Dose of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis) t
    Gilles Montalescot
    Institut de Cardiologie Pitié Salpêtriére University Hospital, Assistence Publique Hôpiteux de Paris APHP, Paris, France
    J Am Coll Cardiol 48:931-8. 2006
    ..We sought to compare the antiplatelet effects of three clopidogrel loading doses (LDs)...
  68. doi request reprint Enoxaparin versus unfractionated heparin in elective percutaneous coronary intervention 1-year results from the STEEPLE (SafeTy and efficacy of enoxaparin in percutaneous coronary intervention patients, an international randomized evaluation) trial
    Gilles Montalescot
    Institut du Coeur, Centre Hospitalier Universitaire Pitie Salpetriere, Paris, France
    JACC Cardiovasc Interv 2:1083-91. 2009
    ..Our purpose was to evaluate long-term mortality and identify factors associated with 1-year mortality in patients who underwent elective percutaneous coronary intervention (PCI)...
  69. pmc Unprotected left main revascularization in patients with acute coronary syndromes
    Gilles Montalescot
    Institut de Cardiologie, Bureau 2 236, Centre Hospitalier Universitaire Pitie Salpetriere, 47 Blvd de l Hopital, 75013 Paris, France
    Eur Heart J 30:2308-17. 2009
    ....
  70. ncbi request reprint B-type natriuretic peptide and echocardiographic determination of ejection fraction in the diagnosis of congestive heart failure in patients with acute dyspnea
    Philippe Gabriel Steg
    Cardiology, Hopital Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, 46 rue Henri Huchard, 75877 Paris Cedex 18, France
    Chest 128:21-9. 2005
    ..Echocardiography and B-type natriuretic peptide (BNP) are diagnostic tests for congestive heart failure (CHF), but an emergency diagnosis can be difficult...
  71. doi request reprint Myocardial infarction after blunt chest trauma: usefulness of cardiac ECG-gated CT and MRI for positive and aetiologic diagnosis
    Gregory Malbranque
    Department of Cardiology, University Hospital Bichat APHP, 46 rue Henri Huchard, Paris, France
    Emerg Radiol 18:271-4. 2011
    ..In these two cases, cardiac CT and MRI were useful to noninvasively explore these lesions...
  72. ncbi request reprint Prognostic significance of renal insufficiency in patients presenting with acute coronary syndrome (the Prospective Multicenter SYCOMORE study)
    Raphaelle Dumaine
    Pitie Salpetriere Hospital, Paris, France
    Am J Cardiol 94:1543-7. 2004
    ..One third of patients with ACS presented with renal insufficiency. After adjustment for potential confounders, decreasing renal function was independently associated with in-hospital death, bleeding, and contrast-induced nephropathy...
  73. pmc Quality of reporting internal and external validity data from randomized controlled trials evaluating stents for percutaneous coronary intervention
    Morgane Ethgen
    Institut National de la Santé et la Recherche Médiale, INSERM U738, Paris, France
    BMC Med Res Methodol 9:24. 2009
    ..The objective of our study was to evaluate the quality of reporting internal and external validity data in published reports of RCTs assessing the stents for percutaneous coronary interventions...
  74. ncbi request reprint Age and lack of beta-blocker therapy are associated with increased long-term mortality after primary coronary angioplasty for acute myocardial infarction
    Jean Michel Juliard
    Division of Cardiology, Hopital Bichat, AP HP, 46 rue Henri Huchard, 75877 Cedex 18, Paris, France
    Int J Cardiol 88:63-8. 2003
    ..Few studies have examined the long-term outcome of primary PTCA for acute myocardial infarction, especially in thrombolysis-eligible patients...
  75. ncbi request reprint Circulating secretory phospholipase A2 activity predicts recurrent events in patients with severe acute coronary syndromes
    Ziad Mallat
    Institut National de la Santé et la Recherche Médicale, INSERM U541, Institut Fédératif de Recherche IRF Circulation, Paris, France
    J Am Coll Cardiol 46:1249-57. 2005
    ..The purpose of this study was to determine the prognostic value of circulating secretory phospholipase A2 (sPLA2) activity in patients with acute coronary syndromes (ACS)...
  76. pmc Impact of collateral flow to the occluded infarct-related artery on clinical outcomes in patients with recent myocardial infarction: a report from the randomized occluded artery trial
    Ph Gabriel Steg
    INSERM U 698 and Département de Cardiologie, Centre Hospitalier Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, Paris Cedex 18, France
    Circulation 121:2724-30. 2010
    ..Collateral flow to the infarct artery territory after acute myocardial infarction may be associated with improved clinical outcomes and may also impact the benefit of subsequent recanalization of an occluded infarct-related artery...
  77. ncbi request reprint Relation of mortality of primary angioplasty during acute myocardial infarction to door-to-Thrombolysis In Myocardial Infarction (TIMI) time
    Jean Michel Juliard
    Cardiology Department, Hopital Bichat, AP HP, 46 rue Henri Huchard, 75877 Paris Cedex 18, France
    Am J Cardiol 91:1401-5. 2003
    ..After linear logistic regression, only age (odds ratio [OR] 1.79 per 10 years), female gender (OR 3.56), and door-to-TIMI 3 time (OR 1.27 per 15 minutes) were independently correlated with in-hospital mortality...
  78. doi request reprint Renal function, atherothrombosis extent, and outcomes in high-risk patients
    Raphaelle L Dumaine
    Pitie Salpetriere University Hospital, Paris, France
    Am Heart J 158:141-148.e1. 2009
    ..Although prior data showed an association between chronic kidney disease (CKD) and atherothrombotic events, little is known about the risk profile and specific outcomes of atherothrombotic outpatients with CKD...
  79. ncbi request reprint Does comorbidity account for the excess mortality in patients with major bleeding in acute myocardial infarction?
    Frederick A Spencer
    Department of Medicine, McMaster University, Faculty of Health Sciences, 1200 Main St W, Hamilton, Canada, L8N 3Z5
    Circulation 116:2793-801. 2007
    ..Because these data are not generalizable to all patients with acute myocardial infarction, we sought to better understand the scope of this problem in a "real-world" setting...
  80. ncbi request reprint Implications of diabetes in patients with acute coronary syndromes. The Global Registry of Acute Coronary Events
    Kristen Franklin
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester 01655, USA
    Arch Intern Med 164:1457-63. 2004
    ..There are limited data describing the presenting characteristics, management, and outcomes of diabetic and nondiabetic patients with an acute coronary syndrome (ACS)...
  81. ncbi request reprint Impact of prehospital thrombolysis for acute myocardial infarction on 1-year outcome: results from the French Nationwide USIC 2000 Registry
    Nicolas Danchin
    Service de cardiologie, Hopital Europeen Georges Pompidou, 20 rue Leblanc, 75015 Paris, France
    Circulation 110:1909-15. 2004
    ..Limited data are available on the impact of prehospital thrombolysis (PHT) in the "real-world" setting...
  82. ncbi request reprint Extent of, and factors associated with, delay to hospital presentation in patients with acute coronary disease (the GRACE registry)
    Robert J Goldberg
    University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Am J Cardiol 89:791-6. 2002
    ....
  83. ncbi request reprint Patterns of use of heparins in ACS. Correlates and hospital outcomes: the Global Registry of Acute Coronary Events (GRACE)
    Werner Klein
    Medizinische Universitätsklinik Graz, Klinische Abteilung für Kardiologie, Auenbruggerplatz 5, Graz, Styria 8036, Austria
    Thromb Haemost 90:519-27. 2003
    ..We can conclude that UFH tends to be used more frequently than LMWH, but hospital outcomes appeared to be better with LMWH after adjusting for covariables...
  84. ncbi request reprint Resting heart rate in cardiovascular disease
    Kim Fox
    Royal Brompton Hospital, Sydney Street, London SW3 6NP, England
    J Am Coll Cardiol 50:823-30. 2007
    ..These findings suggest that the potential role of HR and its modulation should be considered in future cardiovascular guidance documents...
  85. ncbi request reprint Decline in rates of death and heart failure in acute coronary syndromes, 1999-2006
    Keith A A Fox
    Cardiovascular Research, Division of Medical and Radiological Sciences, The University of Edinburgh, Edinburgh, Scotland
    JAMA 297:1892-900. 2007
    ....
  86. ncbi request reprint Is primary angioplasty more effective than prehospital fibrinolysis in diabetics with acute myocardial infarction? Data from the CAPTIM randomized clinical trial
    Eric Bonnefoy
    Service de cardiologie, Hopital Cardio Vasculaire et Pneumologique Louis Pradel, BP Lyon Montchat, 69394 Lyon Cedex 03, France
    Eur Heart J 26:1712-8. 2005
    ..It found a similar incidence of the primary endpoint of death, recurrent MI, or stroke at 30 days with both strategies. We report here the outcome in the diabetic subgroup...
  87. ncbi request reprint [Acute coronary syndromes: a change of paradigm]
    Philippe Gabriel Steg
    Med Sci (Paris) 20:132-3. 2004
  88. ncbi request reprint Revascularization before noncardiac surgery: is there an impact of drug-eluting stent thrombosis?
    Philippe Gabriel Steg
    J Am Coll Cardiol 50:1398; author reply 1399. 2007
  89. ncbi request reprint The diagnostic and prognostic impact of the redefinition of acute myocardial infarction: lessons from the Global Registry of Acute Coronary Events (GRACE)
    Shaun G Goodman
    Canadian Heart Research Centre, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Am Heart J 151:654-60. 2006
    ..The impact and prognostic value of the redefinition of myocardial infarction (MI) with more sensitive markers have not been evaluated prospectively in a large, less selected population with acute coronary syndrome (ACS)...
  90. ncbi request reprint [Acute coronary syndrome with ST-segment elevation]
    Olivier Varenne
    Services de cardiologie I Hôpital Cochin 75679 Paris
    Rev Prat 53:611-8. 2003
    ..New fibrinolytics and optimisation of antithrombotic regimen in association with coronary stents have dramatically reduced in-hospital mortality...
  91. ncbi request reprint WEST: new data on the integration of early thrombolysis and mechanical intervention in the early management of STEMI
    Philippe Gabriel Steg
    Eur Heart J 27:1511-2. 2006
  92. ncbi request reprint Increasing use of single and combination medical therapy in patients hospitalized for acute myocardial infarction in the 21st century: a multinational perspective
    Robert J Goldberg
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, 55 Lake Ave, Worcester, MA 01655, USA
    Arch Intern Med 167:1766-73. 2007
    ..Current practice guidelines recommend the routine use of several effective cardiac medications in hospital survivors of acute myocardial infarction (AMI)...
  93. ncbi request reprint Impact of prior peripheral arterial disease and stroke on outcomes of acute coronary syndromes and effect of evidence-based therapies (from the Global Registry of Acute Coronary Events)
    Debabrata Mukherjee
    Gill Heart Institute and the University of Kentucky, Lexington, Kentucky, USA
    Am J Cardiol 100:1-6. 2007
    ..In conclusion, outcomes after ACS are worse in patients with PAD or stroke, with the highest risk in patients with the 2 conditions and the use of evidence-based therapies are associated with improved outcomes in all ACS subgroups...
  94. ncbi request reprint Adherence to evidence-based therapies after discharge for acute coronary syndromes: an ongoing prospective, observational study
    Kim A Eagle
    University of Michigan Cardiovascular Center, Ann Arbor, Michigan, USA
    Am J Med 117:73-81. 2004
    ..To determine the rates of patient adherence to key evidence-based therapies at 6 months after hospital discharge for an acute coronary syndrome...
  95. ncbi request reprint Combined Abciximab REteplase Stent Study in acute myocardial infarction (CARESS in AMI)
    Carlo Di Mario
    Royal Brompton Hospital, London, United Kingdom
    Am Heart J 148:378-85. 2004
    ..If a mechanical recanalization is likely to be performed in an emergency, it is probably desirable that the patient receives abciximab, the glycoprotein IIb/IIIa antagonist with the strongest evidence of benefit for angioplasty in AMI...
  96. ncbi request reprint Randomized, blinded trial comparing fondaparinux with unfractionated heparin in patients undergoing contemporary percutaneous coronary intervention: Arixtra Study in Percutaneous Coronary Intervention: a Randomized Evaluation (ASPIRE) Pilot Trial
    Shamir R Mehta
    McMaster University and the Population Health Research Institute, Hamilton Health Sciences, General Division, 237 Barton St E, Hamilton, Ontario, Canada L6K 1B8
    Circulation 111:1390-7. 2005
    ..We performed a randomized trial to determine the safety and feasibility of fondaparinux in the percutaneous coronary intervention (PCI) setting...
  97. ncbi request reprint Prevalence and impact of metabolic syndrome on hospital outcomes in acute myocardial infarction
    Marianne Zeller
    Laboratory of Cardiovascular and Experimental Physiopathology and Pharmacology, Faculty of Medicine, University of Burgundy, Dijon, France
    Arch Intern Med 165:1192-8. 2005
    ....
  98. ncbi request reprint Rationale and design of a randomized, double-blind, placebo-controlled trial of ivabradine in patients with stable coronary artery disease and left ventricular systolic dysfunction: the morBidity-mortality EvAlUaTion of the I(f) inhibitor ivabradine in pa
    Kim Fox
    Royal Brompton Hospital, Sydney Street, London, UK
    Am Heart J 152:860-6. 2006
    ..Because patients with coronary artery disease and left ventricular dysfunction are at high risk of cardiac events and death, we hypothesized that they could derive particular benefit from a specific HR-lowering agent such as ivabradine...
  99. ncbi request reprint Trends in acute reperfusion therapy for ST-segment elevation myocardial infarction from 1999 to 2006: we are getting better but we have got a long way to go
    Kim A Eagle
    University of Michigan Cardiovascular Center, Ann Arbor, MI 48109 0477, USA
    Eur Heart J 29:609-17. 2008
    ..Many patients who are eligible for acute reperfusion therapy receive it after substantial delays or not at all. We wanted to determine whether over the years more patients are receiving reperfusion therapy...
  100. ncbi request reprint Use of proven therapies in non-ST-elevation acute coronary syndromes according to evidence-based risk stratification
    Gustavo B F Oliveira
    Dante Pazzanese Institute of Cardiology, Sao Paulo, Brazil
    Am Heart J 153:493-9. 2007
    ..Our objective was to evaluate the relationship between risk stratification and therapeutic decision making in patients with non-ST-segment elevation acute coronary syndromes...
  101. doi request reprint Immediate angioplasty versus standard therapy with rescue angioplasty after thrombolysis in the Combined Abciximab REteplase Stent Study in Acute Myocardial Infarction (CARESS-in-AMI): an open, prospective, randomised, multicentre trial
    Carlo Di Mario
    Royal Brompton Hospital and Imperial College, London UK
    Lancet 371:559-68. 2008
    ..To assess the best management, we randomised patients with STEMI treated by thrombolysis and abciximab at a non-interventional hospital to immediate transfer for PCI, or to standard medical therapy with transfer for rescue angioplasty...