- Time to pregnancy and semen parameters: a cross-sectional study among fertile couples from four European citiesR Slama
INSERM U292, Research in Public Health, 82 rue du General Leclerc, 94276 Le Kremlin Bicetre Cedex, France
Hum Reprod 17:503-15. 2002..In fertile populations, little is known about the association between semen parameters and time to pregnancy (TTP)...
- [Breakthroughs in the study of the influence of environmental factors on male reproductive health]R Slama
INSERM, IFR 69, Unité 569 Epidémiologie, Démographie et Sciences Sociales, 82, rue du General Leclerc, 94276 Le Kremlin Bicetre
Rev Epidemiol Sante Publique 54:167-74. 2006..The concepts on endocrine disruption and testicular dysgenesis syndrome make a link between these two questions...
- Controlling for continuous confounding factors: non- and semiparametric approachesR Slama
INSERM U 569 Epidémiologie, Démographie et Sciences Sociales, IFR69, 82, rue du General Leclerc, 94276 Le Kremlin Bicetre
Rev Epidemiol Sante Publique 53:2S65-80. 2005..These models can be used in exploratory analyses to describe dose-effect relations between the confounder and the health event, and thus help to define a relevant coding for the confounder...
- Influence of paternal age on the risk of spontaneous abortionRemy Slama
U569 Epidemiology, Demography, and Social Sciences, IFR69, National Institute for Health and Medical Research INSERM, F 94276 Le Kremlin Bicetre, France
Am J Epidemiol 161:816-23. 2005..25). In conclusion, the risk of spontaneous abortion increased with increasing paternal age, with a suggestion that the association is stronger for first trimester losses...
- Feasibility of the current-duration approach to studying human fecundityRemy Slama
INSERM, National Institute of Health and Medical Research, U569, IFR 69, Le Kremlin Bicetre, France
Epidemiology 17:440-9. 2006..The current-duration design appears feasible with approximately 5 times as many women eligible for study as for an incident cohort design...
- Epidemiology of male reproductive function: a field searching for toolsR Slama
Unité 569 Epidémiologie, Démographie et Sciences Sociales, INSERM, et INED, IFR69, 82, rue du General Leclerc, 94276 Le Kremlin Bicetre Cedex
Rev Epidemiol Sante Publique 52:221-42. 2004..Neither its causes nor its consequences on fecundity, the ability of the couples to produce a live child, are clearly known. This lack of knowledge may partly be due to methodological difficulties specific to reproductive epidemiology...
- How would a decline in sperm concentration over time influence the probability of pregnancy?Remy Slama
Unité 569 Epidémiologie, Démographie et Sciences Sociales, INSERM and INED the French National Institute for Demographic Studies, IFR69, 82 rue du General Leclerc, 94276 Le Kremlin Bicetre Cedex, France
Epidemiology 15:458-65. 2004..In practice, the amplitude of this expected effect is not well known and the statistical power of time-to-pregnancy studies to detect it has not been explored...
- Does male age affect the risk of spontaneous abortion? An approach using semiparametric regressionRemy Slama
U569 Epidémiologie, Démographie et Sciences Sociales, IFR69, INSERM French Institute for Health and Medical Research and INED French Institute for Demographic Studies, Le Kremlin Bicetre, France
Am J Epidemiol 157:815-24. 2003..61, 95% confidence interval: 0.35, 1.07). Thus, increasing male age could increase the risk of spontaneous abortion when the female partner is less than 30 years of age...
- Traffic-related atmospheric pollutants levels during pregnancy and offspring's term birth weight: a study relying on a land-use regression exposure modelRemy Slama
GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
Environ Health Perspect 115:1283-92. 2007..Some studies have suggested that particulate matter (PM) levels during pregnancy may be associated with birth weight. Road traffic is a major source of fine PM (PM with aero-dynamic diameter < 2.5 microm; PM(2.5))...
- Pregnancy exposure to atmospheric pollutants and placental weight: an approach relying on a dispersion modelAnnisa Rahmalia
INSERM, Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, U823, 38042 Grenoble, France
Environ Int 48:47-55. 2012..The possible underlying biological mechanisms have little been studied in humans, but animal studies suggest an impact of atmospheric pollutants on placental function...
- Maternal exposure to air pollution before and during pregnancy related to changes in newborn's cord blood lymphocyte subpopulations. The EDEN study cohortNour Baïz
INSERM, Institut National de la Sante et de la Recherche Medicale, Epidemiology of Allergic and Respiratory EPAR Department, UMR S707, Paris, France
BMC Pregnancy Childbirth 11:87. 2011..Our aim was to investigate the impacts of maternal exposure to air pollution before and during pregnancy on newborn's immune system...
- When do involuntarily infertile couples choose to seek medical help?Caroline Moreau
INSERM, Institut National de la Sante et de la Recherche Medicale, Unit 822, Epidemiology, Demography, and Social Sciences, Le Kremlin Bicetre, France
Fertil Steril 93:737-44. 2010..To estimate the probability of medical consultation for infertility during the course of a pregnancy attempt and to study its determinants...
- Male gonadal dose of ionizing radiation delivered during X-ray examinations and monthly probability of pregnancy: a population-based retrospective studySandra Sinno-Tellier
INSERM, National Institute of Health and Medical Research, Unité U569 Epidémiologie, Démographie et Sciences Sociales, IFR69, Le Kremlin Bicetre, France
BMC Public Health 6:55. 2006..We aimed to characterize the influence of male gonadal dose of ionizing radiation delivered during radiodiagnostic on the monthly probability of pregnancy...
- Maternal personal exposure to airborne benzene and intrauterine growthRemy Slama
INSERM, Institut National de la Sante et de la Recherche Medicale, University J Fourier Grenoble, Avenir Team Environmental Epidemiology Applied to Fecundity and Reproduction, U823, Institut Albert Bonniot, Grenoble, France
Environ Health Perspect 117:1313-21. 2009..Studies relying on outdoor pollutants measures have reported associations between air pollutants and birth weight...
- Short-term impact of ambient air pollution and air temperature on blood pressure among pregnant womenRegina Hampel
Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology II, Neuherberg, Germany
Epidemiology 22:671-9. 2011..Short-term air pollution effects on BP have not been investigated in pregnant women, who may constitute a vulnerable population...
- Correcting for the influence of sampling conditions on biomarkers of exposure to phenols and phthalates: a 2-step standardization method based on regression residualsMarion Mortamais
Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, INSERM, Institut Albert Bonniot U823, Grenoble, France
Environ Health 11:29. 2012....
- Maternal blood lead levels and the risk of pregnancy-induced hypertension: the EDEN cohort studyChadi Yazbeck
INSERM, U780, IFR69, Villejuif, France
Environ Health Perspect 117:1526-30. 2009..Prior studies revealed associations of environmental lead exposure with risks of hypertension and elevated blood pressure...
- Fine particles, a major threat to childrenJoachim Heinrich
GSF National Research Centre for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
Int J Hyg Environ Health 210:617-22. 2007..Here, we restrict the review on the impact of fine particle exposure on children's health to the following outcomes: infant death, lung function, respiratory symptoms and reproductive outcomes...
- Meeting report: atmospheric pollution and human reproductionRemy Slama
Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Institute of Epidemiology, Neuherberg, Germany
Environ Health Perspect 116:791-8. 2008..There is a growing body of epidemiologic literature reporting associations between atmospheric pollutants and reproductive outcomes, particularly birth weight and gestational duration...
- [Ionizing radiation and health: data and objectives]A Spira
INSERM U 292, Service de Sante Publique, Hopital de Bicetre, 82, rue du General Leclerc, 94276 Le Kremlin Bicetre Cedex, France
Rev Epidemiol Sante Publique 50:3-11. 2002..An extension of the cancer registries to the entire country would be a significant progress in terms of research and surveillance. This must be discussed in terms of potential utility in other domains of public health...
- Selection bias in semen studies due to self-selection of volunteersA Muller
INSERM National Institute For Health and Medical Research U569 IFR69, 94276 Le Kremlin Bicetre Cedex, France
Hum Reprod 19:2838-44. 2004..Reports of a secular decrease in semen quality remain controversial, particularly due to the possibility of selection bias. We aimed to describe the potential bias due to self-selection of volunteers in semen studies involving fecund men...
- Geographic variations in probability of pregnancy in four cities of FranceA Muller
INSERM National Institute For Health and Medical Research U569, IFR 69, 82, rue Général Leclerc, 94276 Le Kremlin Bicetre Cedex, France
Rev Epidemiol Sante Publique 54:55-60. 2006..Our aim was to describe geographic variations in fecundability, the monthly probability of pregnancy, between four cities of France...
- Maternal exposure to nitrogen dioxide during pregnancy and offspring birth weight: comparison of two exposure modelsJohanna Lepeule
INSERM, Avenir Team Environmental Epidemiology Applied to Fecundity and Reproduction, Institut Albert Bonniot, Grenoble, France
Environ Health Perspect 118:1483-9. 2010..Studies of the effects of air pollutants on birth weight often assess exposure with networks of permanent air quality monitoring stations (AQMSs), which have a poor spatial resolution...
- Reproductive life events in the population living in the vicinity of a nuclear waste reprocessing plantR Slama
INSERM, Institut National de la Sante et de la Recherche Medicale, Unité 822 Epidémiologie, Démographie et Sciences Sociales, IFR69 Le Kremlin Bicêtre, France
J Epidemiol Community Health 62:513-21. 2008..A comparative study was conducted on reproductive life events in the general population living near the nuclear waste reprocessing plant in Beaumont-Hague, France and a reference area in Brittany...