Tabassome Simon

Summary

Country: France

Publications

  1. ncbi request reprint [Efficacy and tolerance of propafenone after correction of atrial fibrillation: PEPS pharmaco-epidemiologic study]
    T Simon
    Service de Pharmacologie, CHU Saint Antoine, 27, rue de Chaligny, 75012 Paris
    Arch Mal Coeur Vaiss 95:567-72. 2002
  2. ncbi request reprint Combined glutathione-S-transferase M1 and T1 genetic polymorphism and tacrine hepatotoxicity
    T Simon
    Pharmacology Department, INSERM SC4, Saint Antoine University, Paris, France
    Clin Pharmacol Ther 67:432-7. 2000
  3. ncbi request reprint Impact of age and gender on in-hospital and late mortality after acute myocardial infarction: increased early risk in younger women: results from the French nation-wide USIC registries
    Tabassome Simon
    Department of Pharmacology, Saint Antoine, Pierre et Marie Curie University, 27 rue Chaligny, 75012 AP HP, and Department of Cardiology, Hopital Europeen Georges Pompidou, Paris, France
    Eur Heart J 27:1282-8. 2006
  4. ncbi request reprint [Controversies on the arterial risk of hormone substitution treatment]
    Tabassome Simon
    Departement de Pharmacologie, Universite Paris VI, Faculte de Medecine Saint Antoine, AP HP, Paris, France
    Therapie 59:63-70. 2004
  5. ncbi request reprint Rationale, design and methods of the CASHMERE study
    Tabassome Simon
    Department of Pharmacology, Paris VI University, Saint Antoine University Hospital AP HP, Paris, France
    Fundam Clin Pharmacol 18:131-8. 2004
  6. ncbi request reprint Bisoprolol dose-response relationship in patients with congestive heart failure: a subgroup analysis in the cardiac insufficiency bisoprolol study(CIBIS II)
    T Simon
    Department of Pharmacology, Saint Antoine University Hospital AP HP, 27, rue Chaligny, 75012, Paris, France
    Eur Heart J 24:552-9. 2003
  7. ncbi request reprint Influence of tamoxifen on carotid intima-media thickness in postmenopausal women
    T Simon
    Department of Pharmacology, St Antoine University Hospital, Paris, France
    Circulation 106:2925-9. 2002
  8. pmc Variability of cytochrome P450 1A2 activity over time in young and elderly healthy volunteers
    T Simon
    Department of Pharmacology, Saint Antoine Paris VI University Hospital, Paris, France
    Br J Clin Pharmacol 52:601-4. 2001
  9. ncbi request reprint Sex differences in the prognosis of congestive heart failure: results from the Cardiac Insufficiency Bisoprolol Study (CIBIS II)
    T Simon
    Department of Pharmacology, INSERM SC4, Paris VI University, Saint Antoine University Hospital, rue Chaligny, Paris, France
    Circulation 103:375-80. 2001
  10. ncbi request reprint [Flecainide controlled-release for prevention of atrial fibrillation relapse]
    T Simon
    Service de Pharmacologie, AP HP, Faculte de Medecine Pierre et Marie Curie, site Saint Antoine, Universite Paris 6, 27, rue Chaligny, 75012 Paris
    Arch Mal Coeur Vaiss 99:109-16. 2006

Detail Information

Publications44

  1. ncbi request reprint [Efficacy and tolerance of propafenone after correction of atrial fibrillation: PEPS pharmaco-epidemiologic study]
    T Simon
    Service de Pharmacologie, CHU Saint Antoine, 27, rue de Chaligny, 75012 Paris
    Arch Mal Coeur Vaiss 95:567-72. 2002
    ..The efficacy of the treatment for the maintenance of sinus rhythm is in accordance with previously published results...
  2. ncbi request reprint Combined glutathione-S-transferase M1 and T1 genetic polymorphism and tacrine hepatotoxicity
    T Simon
    Pharmacology Department, INSERM SC4, Saint Antoine University, Paris, France
    Clin Pharmacol Ther 67:432-7. 2000
    ..Glutathione conjugation of tacrine reactive metabolites depends in part on the activity of glutathione-S-transferases (GST), of which two isozymes (GST M1 and GST T1) are polymorphically expressed...
  3. ncbi request reprint Impact of age and gender on in-hospital and late mortality after acute myocardial infarction: increased early risk in younger women: results from the French nation-wide USIC registries
    Tabassome Simon
    Department of Pharmacology, Saint Antoine, Pierre et Marie Curie University, 27 rue Chaligny, 75012 AP HP, and Department of Cardiology, Hopital Europeen Georges Pompidou, Paris, France
    Eur Heart J 27:1282-8. 2006
    ..To determine whether sex differences of in-hospital and after-discharge mortality differ according to the age...
  4. ncbi request reprint [Controversies on the arterial risk of hormone substitution treatment]
    Tabassome Simon
    Departement de Pharmacologie, Universite Paris VI, Faculte de Medecine Saint Antoine, AP HP, Paris, France
    Therapie 59:63-70. 2004
  5. ncbi request reprint Rationale, design and methods of the CASHMERE study
    Tabassome Simon
    Department of Pharmacology, Paris VI University, Saint Antoine University Hospital AP HP, Paris, France
    Fundam Clin Pharmacol 18:131-8. 2004
    ..The results are expected for 2007...
  6. ncbi request reprint Bisoprolol dose-response relationship in patients with congestive heart failure: a subgroup analysis in the cardiac insufficiency bisoprolol study(CIBIS II)
    T Simon
    Department of Pharmacology, Saint Antoine University Hospital AP HP, 27, rue Chaligny, 75012, Paris, France
    Eur Heart J 24:552-9. 2003
    ..Whether all patients with congestive heart failure (CHF) need to reach the target dose of beta-blocker to obtain a benefit in terms of survival remains uncertain...
  7. ncbi request reprint Influence of tamoxifen on carotid intima-media thickness in postmenopausal women
    T Simon
    Department of Pharmacology, St Antoine University Hospital, Paris, France
    Circulation 106:2925-9. 2002
    ..The goal of this study was to determine the influence of tamoxifen on IMT-CCA in menopausal women...
  8. pmc Variability of cytochrome P450 1A2 activity over time in young and elderly healthy volunteers
    T Simon
    Department of Pharmacology, Saint Antoine Paris VI University Hospital, Paris, France
    Br J Clin Pharmacol 52:601-4. 2001
    ..To assess the age-associated changes over time of plasma paraxanthine/caffeine (PAX/CAF) ratios used as a probe for CYP1A2 activity...
  9. ncbi request reprint Sex differences in the prognosis of congestive heart failure: results from the Cardiac Insufficiency Bisoprolol Study (CIBIS II)
    T Simon
    Department of Pharmacology, INSERM SC4, Paris VI University, Saint Antoine University Hospital, rue Chaligny, Paris, France
    Circulation 103:375-80. 2001
    ..We examined whether survival was different in men (n=2132) and women (n=515) enrolled in CIBIS II...
  10. ncbi request reprint [Flecainide controlled-release for prevention of atrial fibrillation relapse]
    T Simon
    Service de Pharmacologie, AP HP, Faculte de Medecine Pierre et Marie Curie, site Saint Antoine, Universite Paris 6, 27, rue Chaligny, 75012 Paris
    Arch Mal Coeur Vaiss 99:109-16. 2006
    ..A new controlled-release (LP) formulation of flecainide was recently introduced. The objectives of this observational study were to evaluate the benefit/risk ratio of LI or LP flecainide treatment for prevention of AF relapse...
  11. ncbi request reprint Five-year survival in patients with ST-segment-elevation myocardial infarction according to modalities of reperfusion therapy: the French Registry on Acute ST-Elevation and Non-ST-Elevation Myocardial Infarction (FAST-MI) 2005 Cohort
    Nicolas Danchin
    Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, Paris, France N D, E P INSERM U 970, Paris, France N D, E P Université Paris Descartes, Paris, France N D, E P Assistance Publique Hôpitaux de Paris, Hopital Bichat, Paris, France P G S INSERM U 698, Paris, France P G S Université Paris Diderot, Paris, France P G S Centre Hospitalier Régional Universitaire de Lille, Lille, France P G Hôpital Jean Minjoz, Besancon, France F S Université de Franche Comté, Besancon, France F S Centre Hospitalier d Annecy, Annecy, France L B Hôpital du Bocage, Dijon, France Y C Université de Bourgogne, Dijon, France Y C Clinique Pasteur, Toulouse, France J Fajadet Centre Hospitalier Régional de Metz Thionville, Metz, France K K Hôpital du Haut Levêque, Pessac, France P C Université Bordeaux Segalen, Bordeaux, France P C Hôpital Rangueil, Toulouse, Department of Embryology and Teratology
    Circulation 129:1629-36. 2014
    ..Although primary percutaneous coronary intervention (pPCI) is the preferred reperfusion method for ST-segment-elevation myocardial infarction, it remains difficult to implement in many areas, and fibrinolytic therapy is still widely used...
  12. doi request reprint [Acute myocardial infarction in the elderly. The FAST-MI registry]
    Etienne Puymirat
    Hopital Europeen Georges Pompidou, Assistance Publique Hopitaux de Paris, Universite Paris Descartes, 75015 Paris, France
    Presse Med 42:1432-41. 2013
    ..In-hospital mortality increases with age, particularly after 85 years, but has decreased compared with previous French surveys. ..
  13. doi request reprint Comparison of bleeding complications and one-year survival of low molecular weight heparin versus unfractioned heparin for acute myocardial infarction in elderly patients. The FAST-MI registry
    Etienne Puymirat
    Division of Coronary Artery Disease and Intensive Cardiac Care, Hopital Europeen Georges Pompidou, Assistance Publique des Hopitaux de Paris, Universite Paris Descartes, Paris, France
    Int J Cardiol 166:106-10. 2013
    ..There are limited data on the safety and efficacy of low molecular weight heparin (LMWH) in elderly patients with acute myocardial infarction (AMI)...
  14. doi request reprint Association of menopause and hormone replacement therapy with large artery remodeling
    Anne Gompel
    Universite Paris Descartes, Assistance Publique Hopitaux de Paris, Hotel Dieu, Paris, France
    Fertil Steril 96:1445-50. 2011
    ..To evaluate the remodeling of large arteries according to age at menopause, duration of menopause, and use of hormone therapy (HT)...
  15. doi request reprint Use of invasive strategy in non-ST-segment elevation myocardial infarction is a major determinant of improved long-term survival: FAST-MI (French Registry of Acute Coronary Syndrome)
    Etienne Puymirat
    Division of Coronary Artery Disease and Intensive Cardiac Care, European Hospital of Georges Pompidou, Assistance Publique des Hopitaux de Paris AP HP, University Paris Descartes, Paris, France
    JACC Cardiovasc Interv 5:893-902. 2012
    ....
  16. doi request reprint Association of changes in clinical characteristics and management with improvement in survival among patients with ST-elevation myocardial infarction
    Etienne Puymirat
    Assistance Publique Hopitaux de Paris AP HP, Hopital Europeen Georges Pompidou, Department of Cardiology, Universite Paris Descartes, and INSERM U 970, Paris, France
    JAMA 308:998-1006. 2012
    ..The contemporary decline in mortality reported in patients with ST-segment elevation myocardial infarction (STEMI) has been attributed mainly to improved use of reperfusion therapy...
  17. doi request reprint Comparison of efficacy and safety of a standard versus a loading dose of clopidogrel for acute myocardial infarction in patients ≥ 75 years of age (from the FAST-MI registry)
    Etienne Puymirat
    Division of Coronary Artery Disease and Intensive Cardiac Care, Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, Paris, France
    Am J Cardiol 108:755-9. 2011
    ..Large-scale randomized trials are still needed to identify the optimal LD of clopidogrel for elderly patients admitted for AMI...
  18. ncbi request reprint Circulating levels of interleukin-17 and cardiovascular outcomes in patients with acute myocardial infarction
    Tabassome Simon
    Department of Clinical Pharmacology, URC EST, Assistance Publique Hopitaux de Paris APHP, Hôpital St Antoine Paris, University of Pierre et Marie Curie, 27 rue Chaligny, 75012 Paris, France
    Eur Heart J 34:570-7. 2013
    ..We investigated the relationship between serum levels of IL-17 and the risk of cardiovascular events in patients with acute myocardial infarction...
  19. doi request reprint Improved outcome of cardiogenic shock at the acute stage of myocardial infarction: a report from the USIK 1995, USIC 2000, and FAST-MI French nationwide registries
    Nadia Aissaoui
    Division of Coronary Artery Disease and Intensive Cardiac Care, Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, Paris, France
    Eur Heart J 33:2535-43. 2012
    ..The historical evolution of incidence and outcome of cardiogenic shock (CS) in acute myocardial infarction (AMI) patients is debated. This study compared outcomes in AMI patients from 1995 to 2005, according to the presence of CS...
  20. doi request reprint Sleep quality and nocturnal hypoxaemia and hypercapnia in children and young adults with cystic fibrosis
    Brigitte Fauroux
    AP HP, Pediatric Pulmonary Department, Hopital Armand Trousseau, Universite Pierre et Marie Curie Paris 6, INSERM U 955, 28 avenue du Docteur Arnold Netter, Paris, France
    Arch Dis Child 97:960-6. 2012
    ..The aim of the study was to evaluate sleep quality and nocturnal gas exchange in patients with cystic fibrosis (CF) and to assess if sleep quality and daytime lung function could predict nocturnal hypoxaemia or hypercapnia...
  21. doi request reprint Clinical events as a function of proton pump inhibitor use, clopidogrel use, and cytochrome P450 2C19 genotype in a large nationwide cohort of acute myocardial infarction: results from the French Registry of Acute ST-Elevation and Non-ST-Elevation Myocard
    Tabassome Simon
    Department of Pharmacology, Clinical Research Unit, APHP, St Antoine Hospital, UMPC Paris 06 University, 27 rue Chaligny, Paris, France
    Circulation 123:474-82. 2011
    ..This analysis compares treatment outcomes for patients in the French Registry of Acute ST-Elevation and Non-ST-Elevation Myocardial Infarction (FAST-MI) who did or did not receive clopidogrel and/or PPIs...
  22. doi request reprint Risk of colorectal high-grade dysplasia and cancer in a prospective observational cohort of patients with inflammatory bowel disease
    Laurent Beaugerie
    Department of Gastroenterology, AP HP, Hôpital Saint Antoine F 75012 and UPMC Univ Paris 06 F 75005, Paris, France
    Gastroenterology 145:166-175.e8. 2013
    ..We analyzed data on CRC development among patients with IBD enrolled in the observational cohort Cancers et Surrisque Associé aux Maladies Inflammatoires Intestinales En France (CESAME)...
  23. doi request reprint Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study
    Laurent Beaugerie
    Department of Gastroenterology, Assistance Publique Hopitaux de Paris AP HP, Hopital Saint Antoine, Universite Pierre et Marie Curie Paris VI, Paris, France
    Lancet 374:1617-25. 2009
    ..Reports of an increased risk of lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease are controversial. We assessed this risk in a prospective observational cohort study...
  24. ncbi request reprint Influence of pravastatin on carotid artery structure and function in dyslipidemic HIV-infected patients receiving antiretroviral therapy
    Franck Boccara
    Department of Pharmacology, Universite Paris Descartes, Faculte de Medecine, INSERM 652, Hopital Europeen Georges Pompidou, Paris, France
    AIDS 20:2395-8. 2006
    ..Age and body mass index were independent determinants of IMT of the CCA. Mean arterial pressure, age, duration of HIV infection and protease inhibitor exposure determined aortic stiffness...
  25. doi request reprint Excess primary intestinal lymphoproliferative disorders in patients with inflammatory bowel disease
    Harry Sokol
    Department of Gastroenterology, AP HP, Hôpital Saint Antoine and UPMC University of Paris, Paris, France
    Inflamm Bowel Dis 18:2063-71. 2012
    ..We assessed this risk in the CESAME French nationwide prospective observational cohort...
  26. ncbi request reprint [Genetic polymorphism of beta-adrenergic receptors and mortality in ischemic heart disease]
    Patrice Jaillon
    Service de Pharmacologie, Hôpital Saint Antoine AP HP et Faculté de Médecine Pierre et Marie Curie, Universite Paris VI, Paris, France
    Therapie 62:1-7. 2007
    ..These data suggest that B2AR genetic polymorphism should be systematically studied in clinical trials in myocardial ischemia, with or without congestive heart failure...
  27. doi request reprint Combined inhibition of CCL2, CX3CR1, and CCR5 abrogates Ly6C(hi) and Ly6C(lo) monocytosis and almost abolishes atherosclerosis in hypercholesterolemic mice
    Christophe Combadiere
    Institut National de la Sante et de la Recherche Medicale, Unit 543, Universite Pierre et Marie Curie, Paris 6, Paris, France
    Circulation 117:1649-57. 2008
    ..Evidence that particular chemokine pathways may cooperate to promote monocyte accumulation into inflamed tissues, particularly atherosclerotic arteries, is still lacking...
  28. doi request reprint Comparison of thrombolysis followed by broad use of percutaneous coronary intervention with primary percutaneous coronary intervention for ST-segment-elevation acute myocardial infarction: data from the french registry on acute ST-elevation myocardial inf
    Nicolas Danchin
    Division of Coronary Artery Disease and Intensive Cardiac Care, Hopital Europeen Georges Pompidou, Assistance Publique des Hôpitaux de Paris and Faculté René Descartes, Universite Paris 5, 20 rue Leblanc, 75015 Paris, France
    Circulation 118:268-76. 2008
    ....
  29. doi request reprint Impact of age and gender interaction on circulating endothelial progenitor cells in healthy subjects
    Alexandra Rousseau
    Clinical Research Unit URC EST and Department of Pharmacology, AP HP, Saint Antoine Hospital, Universite Pierre et Marie Curie Paris 6, Paris, France
    Fertil Steril 93:843-6. 2010
    ..To assess the level of circulating endothelial progenitor cells (CEPC) in cycling women compared with men and menopausal women...
  30. pmc B lymphocytes trigger monocyte mobilization and impair heart function after acute myocardial infarction
    Yasmine Zouggari
    1 Institut National de la Santé et de la Recherche Médicale INSERM, Unit 970, Paris Cardiovascular Research Center, Paris, France 2 Université Paris Descartes, Paris, France 3
    Nat Med 19:1273-80. 2013
    ..This work identifies a crucial interaction between mature B lymphocytes and monocytes after acute myocardial ischemia and identifies new therapeutic targets for acute myocardial infarction. ..
  31. pmc A multicentric randomized controlled trial on the impact of lengthening the interval between neoadjuvant radiochemotherapy and surgery on complete pathological response in rectal cancer (GRECCAR-6 trial): rationale and design
    Jeremie H Lefevre
    Assistance Publique Hopitaux de Paris AP HP, Department of Digestive Surgery, Hopital Saint Antoine, 184, rue du Fbg Saint Antoine, 75012 Paris, France
    BMC Cancer 13:417. 2013
    ..The aim of the present study is to evaluate in 264 patients the rate of pathological complete response rate of rectal cancer after RCT by lengthening the time between RCT and surgery...
  32. doi request reprint Occupational status moderates the association between current perceived stress and high blood pressure: evidence from the IPC cohort study
    Emmanuel Wiernik
    Unité de Psychologie et Psychiatrie de liaison et d urgence, Hopital Europeen Georges Pompidou, Paris, France
    Hypertension 61:571-7. 2013
    ..The association between current perceived stress and BP depends on occupational status. This interaction may account for previous conflicting results and warrants further studies to explore its underlying mechanisms...
  33. pmc Variability of intensive care admission decisions for the very elderly
    Ariane Boumendil
    Unité de Recherche en Épidémiologie Systèmes d Information et Modélisation U707, Institut National de la Sante et de la Recherche Medicale, Paris, France
    PLoS ONE 7:e34387. 2012
    ..In France, the likelihood that a very elderly person will be admitted to an ICU varies widely from one hospital to another. Influence of intensive care admission on patients' outcome remains unclear...
  34. ncbi request reprint Selection of intensive care unit admission criteria for patients aged 80 years and over and compliance of emergency and intensive care unit physicians with the selected criteria: An observational, multicenter, prospective study
    Maite Garrouste-Orgeas
    Saint Joseph Hospital Network, Medical Chirurgical ICU, Paris, France
    Crit Care Med 37:2919-28. 2009
    ..To describe intensive care unit referral decisions by emergency room physicians in patients aged > or =80 yrs...
  35. doi request reprint Impact of early statin therapy on development of atrial fibrillation at the acute stage of myocardial infarction: data from the FAST-MI register
    Nicolas Danchin
    Cardiology Department, Hoˆpital Europe en Georges Pompidou and Universite Paris Descartes, Paris, France
    Heart 96:1809-14. 2010
    ..The aim of this study was to determine correlations between early statin therapy and atrial fibrillation in acute myocardial infarction...
  36. doi request reprint Comparison of routine and on-demand prescription of chest radiographs in mechanically ventilated adults: a multicentre, cluster-randomised, two-period crossover study
    Gilles Hejblum
    U707, Institut National de la Sante et de la Recherche Medicale, Paris, France
    Lancet 374:1687-93. 2009
    ..By comparison between routine and on-demand strategies, we aimed to establish which strategy was more efficient and effective for optimum patient care...
  37. ncbi request reprint Renin-angiotensin system antagonists and clinical outcomes in stable coronary artery disease without heart failure
    Emmanuel Sorbets
    Département Hospitalo Universitaire FIRE, Universite Paris Diderot, Sorbonne Paris Cité, Paris, France Inserm U 1148, Paris, France Hôpital Bichat, AP HP, Paris, France Hôpital Avicenne, AP HP, Bobigny, France Université Paris XIII, Bobigny, France
    Eur Heart J 35:1760-8. 2014
    ....
  38. pmc Pulmonary acceleration time to optimize the timing of lung transplant in cystic fibrosis
    Thibaud Damy
    Department of Cardiology, AP HP, Henri Mondor Hospital, Creteil, France
    Pulm Circ 2:75-83. 2012
    ..001) but not in patients with sPAP>35 mmHg. By multivariate analysis, FEV(1)and nocturnal desaturation were the main determinants of reduced PAT. A PAT<101 ms reduction is a promising tool for timing of lung transplantation in CF...
  39. ncbi request reprint Lactadherin deficiency leads to apoptotic cell accumulation and accelerated atherosclerosis in mice
    Hafid Ait-Oufella
    Institut National de la Sante et de la Recherche Medicale, Unit 689, Centre de Recherché Cardiovasculaire Lariboisière, 41 Bd de la Chapelle, 75010, Paris, France
    Circulation 115:2168-77. 2007
    ..Atherosclerosis is an immunoinflammatory disease; however, the key factors responsible for the maintenance of immune regulation in a proinflammatory milieu are poorly understood...
  40. ncbi request reprint Circulating secretory phospholipase A2 activity and risk of incident coronary events in healthy men and women: the EPIC-Norfolk study
    Ziad Mallat
    INSERM U689, Centre de Recherché Cardiovasculaire Lariboisière, Paris, France
    Arterioscler Thromb Vasc Biol 27:1177-83. 2007
    ..To assess the association between secretory phospholipase A2 (sPLA2) activity, which encompasses several types of sPLA2, and cardiovascular disease (CAD) in healthy individuals...
  41. ncbi request reprint [Management of cardiovascular risk in the peri-menopausal woman--a consensus statement of European cardiologists and gynaecologists]
    Peter Collins
    NHLI, Imperial College London, Royal Brompton Hospital, London, Wielka Brytania
    Kardiol Pol 65:1331-46; discussion 1347-49. 2007
  42. ncbi request reprint Estrogen plus progestin and risk of venous thrombosis
    Pierre Yves Scarabin
    JAMA 293:1322; author reply 1322-3. 2005
  43. ncbi request reprint Non-interventional research and usual care: definition, regulatory aspects, difficulties and recommendations
    Francois Lemaire
    Medical Intensive Care, Henri Mondor Hospital, Creteil, France
    Therapie 63:103-6, 97-101. 2008
    ....
  44. ncbi request reprint Management of cardiovascular risk in the peri-menopausal woman: a consensus statement of European cardiologists and gynaecologists
    Peter Collins
    NHLI, Imperial College London, Royal Brompton Hospital, Dovehouse Street, London SW3 6LY, UK
    Eur Heart J 28:2028-40. 2007
    ....