Tabassome Simon

Summary

Country: France

Publications

  1. ncbi Clinical events as a function of proton pump inhibitor use, clopidogrel use, and cytochrome P450 2C19 genotype in a large nationwide cohort of acute myocardial infarction: results from the French Registry of Acute ST-Elevation and Non-ST-Elevation Myocard
    Tabassome Simon
    Department of Pharmacology, Clinical Research Unit, APHP, St Antoine Hospital, UMPC Paris 06 University, 27 rue Chaligny, Paris, France
    Circulation 123:474-82. 2011
  2. ncbi Circulating levels of interleukin-17 and cardiovascular outcomes in patients with acute myocardial infarction
    Tabassome Simon
    Department of Clinical Pharmacology, URC EST, Assistance Publique Hopitaux de Paris APHP, Hôpital St Antoine Paris, University of Pierre et Marie Curie, 27 rue Chaligny, 75012 Paris, France
    Eur Heart J 34:570-7. 2013
  3. ncbi Genetic determinants of response to clopidogrel and cardiovascular events
    Tabassome Simon
    Assistance Publique Hopitaux de Paris, Hopital Saint Antoine, and Universite Pierre et Marie Curie, Paris 06, France
    N Engl J Med 360:363-75. 2009
  4. ncbi Effect of paraoxonase-1 polymorphism on clinical outcomes in patients treated with clopidogrel after an acute myocardial infarction
    T Simon
    Assistance Publique Hopitaux de Paris APHP, Hopital St Antoine, URC EST, Paris, France
    Clin Pharmacol Ther 90:561-7. 2011
  5. ncbi [Impact of genetic polymorphisms in the clinical response of oral inhibitors of the platelet P2Y12 adenosine diphosphate (ADP) receptor]
    T Simon
    Service de Pharmacologie, Universite Pierre et Marie Curie Paris 6, Assistance Publique Hopitaux de Paris, France
    Ann Cardiol Angeiol (Paris) 59:S42-6. 2010
  6. ncbi Association of changes in clinical characteristics and management with improvement in survival among patients with ST-elevation myocardial infarction
    Etienne Puymirat
    Assistance Publique Hopitaux de Paris AP HP, Hopital Europeen Georges Pompidou, Department of Cardiology, Universite Paris Descartes, and INSERM U 970, Paris, France
    JAMA 308:998-1006. 2012
  7. ncbi Use of invasive strategy in non-ST-segment elevation myocardial infarction is a major determinant of improved long-term survival: FAST-MI (French Registry of Acute Coronary Syndrome)
    Etienne Puymirat
    Division of Coronary Artery Disease and Intensive Cardiac Care, European Hospital of Georges Pompidou, Assistance Publique des Hopitaux de Paris AP HP, University Paris Descartes, Paris, France
    JACC Cardiovasc Interv 5:893-902. 2012
  8. ncbi Comparison of efficacy and safety of a standard versus a loading dose of clopidogrel for acute myocardial infarction in patients ≥ 75 years of age (from the FAST-MI registry)
    Etienne Puymirat
    Division of Coronary Artery Disease and Intensive Cardiac Care, Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, Paris, France
    Am J Cardiol 108:755-9. 2011
  9. ncbi Improved outcome of cardiogenic shock at the acute stage of myocardial infarction: a report from the USIK 1995, USIC 2000, and FAST-MI French nationwide registries
    Nadia Aissaoui
    Division of Coronary Artery Disease and Intensive Cardiac Care, Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, Paris, France
    Eur Heart J 33:2535-43. 2012
  10. ncbi Excess primary intestinal lymphoproliferative disorders in patients with inflammatory bowel disease
    Harry Sokol
    Department of Gastroenterology, AP HP, Hôpital Saint Antoine and UPMC University of Paris, Paris, France
    Inflamm Bowel Dis 18:2063-71. 2012

Detail Information

Publications28

  1. ncbi Clinical events as a function of proton pump inhibitor use, clopidogrel use, and cytochrome P450 2C19 genotype in a large nationwide cohort of acute myocardial infarction: results from the French Registry of Acute ST-Elevation and Non-ST-Elevation Myocard
    Tabassome Simon
    Department of Pharmacology, Clinical Research Unit, APHP, St Antoine Hospital, UMPC Paris 06 University, 27 rue Chaligny, Paris, France
    Circulation 123:474-82. 2011
    ..This analysis compares treatment outcomes for patients in the French Registry of Acute ST-Elevation and Non-ST-Elevation Myocardial Infarction (FAST-MI) who did or did not receive clopidogrel and/or PPIs...
  2. ncbi Circulating levels of interleukin-17 and cardiovascular outcomes in patients with acute myocardial infarction
    Tabassome Simon
    Department of Clinical Pharmacology, URC EST, Assistance Publique Hopitaux de Paris APHP, Hôpital St Antoine Paris, University of Pierre et Marie Curie, 27 rue Chaligny, 75012 Paris, France
    Eur Heart J 34:570-7. 2013
    ..We investigated the relationship between serum levels of IL-17 and the risk of cardiovascular events in patients with acute myocardial infarction...
  3. ncbi Genetic determinants of response to clopidogrel and cardiovascular events
    Tabassome Simon
    Assistance Publique Hopitaux de Paris, Hopital Saint Antoine, and Universite Pierre et Marie Curie, Paris 06, France
    N Engl J Med 360:363-75. 2009
    ..The effect of these determinants on clinical outcomes after an acute myocardial infarction is unknown...
  4. ncbi Effect of paraoxonase-1 polymorphism on clinical outcomes in patients treated with clopidogrel after an acute myocardial infarction
    T Simon
    Assistance Publique Hopitaux de Paris APHP, Hopital St Antoine, URC EST, Paris, France
    Clin Pharmacol Ther 90:561-7. 2011
    ..87, 95% CI 2.52-18.72 and adjusted HR 3.06, 95% CI 1.47-6.41). Unlike CYP2C19 polymorphism, PON1 (Q192R) polymorphism is not a major pharmacogenetic contributor of clinical response to clopidogrel in AMI patients...
  5. ncbi [Impact of genetic polymorphisms in the clinical response of oral inhibitors of the platelet P2Y12 adenosine diphosphate (ADP) receptor]
    T Simon
    Service de Pharmacologie, Universite Pierre et Marie Curie Paris 6, Assistance Publique Hopitaux de Paris, France
    Ann Cardiol Angeiol (Paris) 59:S42-6. 2010
    ..This article reviews the role of genetic polymorphisms in the clinical impact of oral inhibitors of the platelet P2Y12 adenosine diphosphate (ADP) receptor...
  6. ncbi Association of changes in clinical characteristics and management with improvement in survival among patients with ST-elevation myocardial infarction
    Etienne Puymirat
    Assistance Publique Hopitaux de Paris AP HP, Hopital Europeen Georges Pompidou, Department of Cardiology, Universite Paris Descartes, and INSERM U 970, Paris, France
    JAMA 308:998-1006. 2012
    ..The contemporary decline in mortality reported in patients with ST-segment elevation myocardial infarction (STEMI) has been attributed mainly to improved use of reperfusion therapy...
  7. ncbi Use of invasive strategy in non-ST-segment elevation myocardial infarction is a major determinant of improved long-term survival: FAST-MI (French Registry of Acute Coronary Syndrome)
    Etienne Puymirat
    Division of Coronary Artery Disease and Intensive Cardiac Care, European Hospital of Georges Pompidou, Assistance Publique des Hopitaux de Paris AP HP, University Paris Descartes, Paris, France
    JACC Cardiovasc Interv 5:893-902. 2012
    ....
  8. ncbi Comparison of efficacy and safety of a standard versus a loading dose of clopidogrel for acute myocardial infarction in patients ≥ 75 years of age (from the FAST-MI registry)
    Etienne Puymirat
    Division of Coronary Artery Disease and Intensive Cardiac Care, Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, Paris, France
    Am J Cardiol 108:755-9. 2011
    ..Large-scale randomized trials are still needed to identify the optimal LD of clopidogrel for elderly patients admitted for AMI...
  9. ncbi Improved outcome of cardiogenic shock at the acute stage of myocardial infarction: a report from the USIK 1995, USIC 2000, and FAST-MI French nationwide registries
    Nadia Aissaoui
    Division of Coronary Artery Disease and Intensive Cardiac Care, Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, Paris, France
    Eur Heart J 33:2535-43. 2012
    ..The historical evolution of incidence and outcome of cardiogenic shock (CS) in acute myocardial infarction (AMI) patients is debated. This study compared outcomes in AMI patients from 1995 to 2005, according to the presence of CS...
  10. ncbi Excess primary intestinal lymphoproliferative disorders in patients with inflammatory bowel disease
    Harry Sokol
    Department of Gastroenterology, AP HP, Hôpital Saint Antoine and UPMC University of Paris, Paris, France
    Inflamm Bowel Dis 18:2063-71. 2012
    ..We assessed this risk in the CESAME French nationwide prospective observational cohort...
  11. ncbi Association of menopause and hormone replacement therapy with large artery remodeling
    Anne Gompel
    Universite Paris Descartes, Assistance Publique Hopitaux de Paris, Hotel Dieu, Paris, France
    Fertil Steril 96:1445-50. 2011
    ..To evaluate the remodeling of large arteries according to age at menopause, duration of menopause, and use of hormone therapy (HT)...
  12. ncbi Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study
    Laurent Beaugerie
    Department of Gastroenterology, Assistance Publique Hopitaux de Paris AP HP, Hopital Saint Antoine, Universite Pierre et Marie Curie Paris VI, Paris, France
    Lancet 374:1617-25. 2009
    ..Reports of an increased risk of lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease are controversial. We assessed this risk in a prospective observational cohort study...
  13. ncbi Impact of age and gender on in-hospital and late mortality after acute myocardial infarction: increased early risk in younger women: results from the French nation-wide USIC registries
    Tabassome Simon
    Department of Pharmacology, Saint Antoine, Pierre et Marie Curie University, 27 rue Chaligny, 75012 AP HP, and Department of Cardiology, Hopital Europeen Georges Pompidou, Paris, France
    Eur Heart J 27:1282-8. 2006
    ..To determine whether sex differences of in-hospital and after-discharge mortality differ according to the age...
  14. ncbi Comparison of thrombolysis followed by broad use of percutaneous coronary intervention with primary percutaneous coronary intervention for ST-segment-elevation acute myocardial infarction: data from the french registry on acute ST-elevation myocardial inf
    Nicolas Danchin
    Division of Coronary Artery Disease and Intensive Cardiac Care, Hopital Europeen Georges Pompidou, Assistance Publique des Hôpitaux de Paris and Faculté René Descartes, Universite Paris 5, 20 rue Leblanc, 75015 Paris, France
    Circulation 118:268-76. 2008
    ....
  15. ncbi Non-interventional research and usual care: definition, regulatory aspects, difficulties and recommendations
    Francois Lemaire
    Medical Intensive Care, Henri Mondor Hospital, Creteil, France
    Therapie 63:103-6, 97-101. 2008
    ....
  16. ncbi Combined inhibition of CCL2, CX3CR1, and CCR5 abrogates Ly6C(hi) and Ly6C(lo) monocytosis and almost abolishes atherosclerosis in hypercholesterolemic mice
    Christophe Combadiere
    Institut National de la Sante et de la Recherche Medicale, Unit 543, Universite Pierre et Marie Curie, Paris 6, Paris, France
    Circulation 117:1649-57. 2008
    ..Evidence that particular chemokine pathways may cooperate to promote monocyte accumulation into inflamed tissues, particularly atherosclerotic arteries, is still lacking...
  17. ncbi Variability of intensive care admission decisions for the very elderly
    Ariane Boumendil
    Unité de Recherche en Épidémiologie Systèmes d Information et Modélisation U707, Institut National de la Sante et de la Recherche Medicale, Paris, France
    PLoS ONE 7:e34387. 2012
    ..Influence of intensive care admission on patients' outcome remains unclear. TRIAL REGISTRATION: ClinicalTrials.gov NCT00912600...
  18. ncbi [Genetic polymorphism of beta-adrenergic receptors and mortality in ischemic heart disease]
    Patrice Jaillon
    Service de Pharmacologie, Hôpital Saint Antoine AP HP et Faculté de Médecine Pierre et Marie Curie, Universite Paris VI, Paris, France
    Therapie 62:1-7. 2007
    ..These data suggest that B2AR genetic polymorphism should be systematically studied in clinical trials in myocardial ischemia, with or without congestive heart failure...
  19. ncbi Occupational status moderates the association between current perceived stress and high blood pressure: evidence from the IPC cohort study
    Emmanuel Wiernik
    Unité de Psychologie et Psychiatrie de liaison et d urgence, Hopital Europeen Georges Pompidou, Paris, France
    Hypertension 61:571-7. 2013
    ..The association between current perceived stress and BP depends on occupational status. This interaction may account for previous conflicting results and warrants further studies to explore its underlying mechanisms...
  20. ncbi Effect of two oral doses of 17beta-estradiol associated with dydrogesterone on thrombin generation in healthy menopausal women: a randomized double-blind placebo-controlled study
    Alexandra Rousseau
    Department of Clinical Pharmacology, APHP, Saint Antoine Hospital, Paris University, France
    Fundam Clin Pharmacol 24:239-45. 2010
    ..The two doses of 17beta-estradiol induced in a similar degree an acceleration of the initiation and propagation phase of tissue factor triggered thrombin generation and a significant increase of FVII coagulant activity...
  21. ncbi Comparison of routine and on-demand prescription of chest radiographs in mechanically ventilated adults: a multicentre, cluster-randomised, two-period crossover study
    Gilles Hejblum
    U707, Institut National de la Sante et de la Recherche Medicale, Paris, France
    Lancet 374:1687-93. 2009
    ..By comparison between routine and on-demand strategies, we aimed to establish which strategy was more efficient and effective for optimum patient care...
  22. ncbi Selection of intensive care unit admission criteria for patients aged 80 years and over and compliance of emergency and intensive care unit physicians with the selected criteria: An observational, multicenter, prospective study
    Maite Garrouste-Orgeas
    Saint Joseph Hospital Network, Medical Chirurgical ICU, Paris, France
    Crit Care Med 37:2919-28. 2009
    ..To describe intensive care unit referral decisions by emergency room physicians in patients aged > or =80 yrs...
  23. ncbi Sleep quality and nocturnal hypoxaemia and hypercapnia in children and young adults with cystic fibrosis
    Brigitte Fauroux
    AP HP, Pediatric Pulmonary Department, Hopital Armand Trousseau, Universite Pierre et Marie Curie Paris 6, INSERM U 955, 28 avenue du Docteur Arnold Netter, Paris, France
    Arch Dis Child 97:960-6. 2012
    ..The aim of the study was to evaluate sleep quality and nocturnal gas exchange in patients with cystic fibrosis (CF) and to assess if sleep quality and daytime lung function could predict nocturnal hypoxaemia or hypercapnia...
  24. ncbi Impact of early statin therapy on development of atrial fibrillation at the acute stage of myocardial infarction: data from the FAST-MI register
    Nicolas Danchin
    Cardiology Department, Hoˆpital Europe en Georges Pompidou and Universite Paris Descartes, Paris, France
    Heart 96:1809-14. 2010
    ..The aim of this study was to determine correlations between early statin therapy and atrial fibrillation in acute myocardial infarction...
  25. ncbi Impact of age and gender interaction on circulating endothelial progenitor cells in healthy subjects
    Alexandra Rousseau
    Clinical Research Unit URC EST and Department of Pharmacology, AP HP, Saint Antoine Hospital, Universite Pierre et Marie Curie Paris 6, Paris, France
    Fertil Steril 93:843-6. 2010
    ..To assess the level of circulating endothelial progenitor cells (CEPC) in cycling women compared with men and menopausal women...
  26. ncbi Circulating secretory phospholipase A2 activity and risk of incident coronary events in healthy men and women: the EPIC-Norfolk study
    Ziad Mallat
    INSERM U689, Centre de Recherché Cardiovasculaire Lariboisière, Paris, France
    Arterioscler Thromb Vasc Biol 27:1177-83. 2007
    ..To assess the association between secretory phospholipase A2 (sPLA2) activity, which encompasses several types of sPLA2, and cardiovascular disease (CAD) in healthy individuals...
  27. ncbi Influence of pravastatin on carotid artery structure and function in dyslipidemic HIV-infected patients receiving antiretroviral therapy
    Franck Boccara
    Department of Pharmacology, , , INSERM 652, , Paris, France
    AIDS 20:2395-8. 2006
    ..Age and body mass index were independent determinants of IMT of the CCA. Mean arterial pressure, age, duration of HIV infection and protease inhibitor exposure determined aortic stiffness...
  28. ncbi Rationale, design and methods of the CASHMERE study
    Tabassome Simon
    Department of Pharmacology, Paris VI University, Saint Antoine University Hospital AP HP, Paris, France
    Fundam Clin Pharmacol 18:131-8. 2004
    ..The results are expected for 2007...