- T cell autoreactivity to proinsulin epitopes in diabetic patients and healthy subjectsG Semana
Center of Neurologic Diseases, Brigham and Women s Hospital, Laboratory of Molecular Immunology, Boston, MA, USA
J Autoimmun 12:259-67. 1999..However, the significantly higher 3H-thymidine incorporation after CD3-CD28 triggering showed that peptide specific T cells were capable of a significant response with a stronger TCR signal...
- [Synopsis of the conferences F. Lhermitte. Immunomodulation and induction of tolerance in MS]G Semana
Laboratoire Universitaire d Immunologie, Universite de Rennes I, Rennes, France
Rev Neurol (Paris) 159:242-4. 2003
- Genetic and functional studies in multiple sclerosis patients from Martinique attest for a specific and direct role of the HLA-DR locus in the syndromeE Quelvennec
Laboratoire Universitaire d Immunologie UPRES EA 1257 IFR 97, Université de, Rennes 1 and Etablissement Français du Sang Bretagne Rennes, France
Tissue Antigens 61:166-71. 2003....
- A second-generation genomic screen for multiple sclerosisS J Kenealy
Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, TN 37232 0700, USA
Am J Hum Genet 75:1070-8. 2004..17 in the U.S. DR2+ families), and 16q (HLOD=2.32 in all DR2+ families and HLOD=2.13 in the U.S. DR2+ families). These data suggest several regions that warrant further investigation in the search for MS susceptibility genes...
- Soluble human leucocyte antigen-G molecules in peripheral blood haematopoietic stem cell transplantation: a specific role to prevent acute graft-versus-host disease and a link with regulatory T cellsA Le Maux
UPRES EA 3889 Immunologie Hématologie, Faculte de Medecine, Universite de Rennes 1, France
Clin Exp Immunol 152:50-6. 2008....
- IL2RA and IL7RA genes confer susceptibility for multiple sclerosis in two independent European populationsF Weber
Max Planck Institute of Psychiatry, Munich, Germany
Genes Immun 9:259-63. 2008..1 to 1.5. The discovery and validation of new genetic risk factors in independent populations may help toward the understanding of MS pathogenesis by providing valuable information on biological pathways to be investigated...
- HLA-DRB1*15 allele influences the later course of relapsing remitting multiple sclerosisI Cournu-Rebeix
INSERM, UMRS 546, Paris, France
Genes Immun 9:570-4. 2008..However, we show for the first time that HLA-DRB1*15 allele modulates the course of MS for relapsing-remitting (RR) onset patients likely by precipitating the secondary progressive (SP) phase...