Philippe Seguin

Summary

Country: France

Publications

  1. ncbi request reprint Atrial fibrillation in trauma patients requiring intensive care
    Philippe Seguin
    Hopital Pontchaillou, Surgical Intensive Care Unit, 2 rue Henri Le Guilloux, Rennes Cedex 9, 35033 Rennes, France
    Intensive Care Med 32:398-404. 2006
  2. doi request reprint Are enterococci playing a role in postoperative peritonitis in critically ill patients?
    P Seguin
    Service de Réanimation Chirurgicale, CHU Rennes, 35033, Rennes, France
    Eur J Clin Microbiol Infect Dis 31:1479-85. 2012
  3. ncbi request reprint [Testing nasogastric tube placement: evaluation of three different methods in intensive care unit]
    P Seguin
    Service de Réanimation Chirurgicale, Hopital Pontchaillou, 2, rue Henri Le Guilloux, 35033 Rennes cedex 09, France
    Ann Fr Anesth Reanim 24:594-9. 2005
  4. ncbi request reprint Factors associated with multidrug-resistant bacteria in secondary peritonitis: impact on antibiotic therapy
    P Seguin
    Service de Réanimation Chirurgicale Inserm U620, Hopital de Pontchaillou, Rennes, France
    Clin Microbiol Infect 12:980-5. 2006
  5. doi request reprint Plasma and peritoneal concentration following continuous infusion of cefotaxime in patients with secondary peritonitis
    Philippe Seguin
    Service de Réanimation Chirurgicale Inserm U620, Universite Rennes 1, Hopital de Pontchaillou, Rennes Cedex 9, Rennes, France
    J Antimicrob Chemother 63:564-7. 2009
  6. ncbi request reprint Risk factors for multidrug-resistant bacteria in patients with post-operative peritonitis requiring intensive care
    Philippe Seguin
    Service de Réanimation Chirurgicale, Universite Rennes 1, INSERM U991, Hopital de Pontchaillou, 2 rue Henri Le Guilloux, 35033 Rennes Cedex 9, Rennes, France
    J Antimicrob Chemother 65:342-6. 2010
  7. ncbi request reprint Effectiveness of simple daily sensitization of physicians to the duration of central venous and urinary tract catheterization
    Philippe Seguin
    Service de Réanimation Chirurgicale, INSERM U991, Universite Rennes 1, Hopital de Pontchaillou, 2, rue Henri Le Guilloux, 35033, Rennes Cedex 9, France
    Intensive Care Med 36:1202-6. 2010
  8. pmc Atrial fibrillation is not just an artefact in the ICU
    Philippe Seguin
    Service d anesthésie réanimation 1, Service de Réanimation Chirurgicale, Hôpital Pontchailllou, 2 rue Henri Le Guilloux, 35033 Rennes Cedex, France
    Crit Care 14:182. 2010
  9. doi request reprint Determination of capillary hemoglobin levels using the HemoCue system in intensive care patients
    Philippe Seguin
    Service de Réanimation Chirurgicale, Universite Rennes 1, INSERM U991, Hopital Pontchaillou, 2 rue Henri Le Guilloux, 35033 Rennes Cedex 9, Rennes, France
    J Crit Care 26:423-7. 2011
  10. pmc Dopexamine and norepinephrine versus epinephrine on gastric perfusion in patients with septic shock: a randomized study [NCT00134212]
    Philippe Seguin
    Service de Réanimation Chirurgicale Inserm U620, Hopital de Pontchaillou, Universite de Rennes 1, Rennes, France
    Crit Care 10:R32. 2006

Collaborators

Detail Information

Publications34

  1. ncbi request reprint Atrial fibrillation in trauma patients requiring intensive care
    Philippe Seguin
    Hopital Pontchaillou, Surgical Intensive Care Unit, 2 rue Henri Le Guilloux, Rennes Cedex 9, 35033 Rennes, France
    Intensive Care Med 32:398-404. 2006
    ..To evaluate the incidence and risk factors of atrial fibrillation (AF) in trauma patients...
  2. doi request reprint Are enterococci playing a role in postoperative peritonitis in critically ill patients?
    P Seguin
    Service de Réanimation Chirurgicale, CHU Rennes, 35033, Rennes, France
    Eur J Clin Microbiol Infect Dis 31:1479-85. 2012
    ..Previous antibiotic use before reoperation was a key factor in predicting the subsequent recovery of enterococci...
  3. ncbi request reprint [Testing nasogastric tube placement: evaluation of three different methods in intensive care unit]
    P Seguin
    Service de Réanimation Chirurgicale, Hopital Pontchaillou, 2, rue Henri Le Guilloux, 35033 Rennes cedex 09, France
    Ann Fr Anesth Reanim 24:594-9. 2005
    ..Evaluation of three methods (aspiration of gastric fluid, pH measurement of gastric fluid, and insufflation of air) in order to determine the right position of the nasogastric (NG) tube...
  4. ncbi request reprint Factors associated with multidrug-resistant bacteria in secondary peritonitis: impact on antibiotic therapy
    P Seguin
    Service de Réanimation Chirurgicale Inserm U620, Hopital de Pontchaillou, Rennes, France
    Clin Microbiol Infect 12:980-5. 2006
    ..In conclusion, knowledge of these two factors may provide a more rational basis for selecting initial antimicrobial therapy for patients with secondary peritonitis...
  5. doi request reprint Plasma and peritoneal concentration following continuous infusion of cefotaxime in patients with secondary peritonitis
    Philippe Seguin
    Service de Réanimation Chirurgicale Inserm U620, Universite Rennes 1, Hopital de Pontchaillou, Rennes Cedex 9, Rennes, France
    J Antimicrob Chemother 63:564-7. 2009
    ..The aim of this study was to determine the steady-state plasma and peritoneal concentrations of cefotaxime and its metabolite desacetyl-cefotaxime administered by continuous infusion to critically ill patients with secondary peritonitis...
  6. ncbi request reprint Risk factors for multidrug-resistant bacteria in patients with post-operative peritonitis requiring intensive care
    Philippe Seguin
    Service de Réanimation Chirurgicale, Universite Rennes 1, INSERM U991, Hopital de Pontchaillou, 2 rue Henri Le Guilloux, 35033 Rennes Cedex 9, Rennes, France
    J Antimicrob Chemother 65:342-6. 2010
    ..This prospective non-interventional study investigated the risk factors for multidrug-resistant bacteria (MDRB) in patients with post-operative peritonitis (POP), to provide guidance for empirical antimicrobial therapy...
  7. ncbi request reprint Effectiveness of simple daily sensitization of physicians to the duration of central venous and urinary tract catheterization
    Philippe Seguin
    Service de Réanimation Chirurgicale, INSERM U991, Universite Rennes 1, Hopital de Pontchaillou, 2, rue Henri Le Guilloux, 35033, Rennes Cedex 9, France
    Intensive Care Med 36:1202-6. 2010
    ..To evaluate the effectiveness of simple daily sensitization of physicians to the duration of central venous and urinary tract catheterization, and impact on infection rates...
  8. pmc Atrial fibrillation is not just an artefact in the ICU
    Philippe Seguin
    Service d anesthésie réanimation 1, Service de Réanimation Chirurgicale, Hôpital Pontchailllou, 2 rue Henri Le Guilloux, 35033 Rennes Cedex, France
    Crit Care 14:182. 2010
    ..How such a finding could modify the therapeutic approach remains elusive. The impact of AF on mortality is not clearly demonstrated in the ICU, with AF reflecting essentially the severity of the underlying disease...
  9. doi request reprint Determination of capillary hemoglobin levels using the HemoCue system in intensive care patients
    Philippe Seguin
    Service de Réanimation Chirurgicale, Universite Rennes 1, INSERM U991, Hopital Pontchaillou, 2 rue Henri Le Guilloux, 35033 Rennes Cedex 9, Rennes, France
    J Crit Care 26:423-7. 2011
    ..The study aimed to compare hemoglobin (Hb) values determined using the portable HemoCue system (HemoCue Hb 201+; HemoCue AB, Ängelholm, Sweden) with laboratory Hb level determination...
  10. pmc Dopexamine and norepinephrine versus epinephrine on gastric perfusion in patients with septic shock: a randomized study [NCT00134212]
    Philippe Seguin
    Service de Réanimation Chirurgicale Inserm U620, Hopital de Pontchaillou, Universite de Rennes 1, Rennes, France
    Crit Care 10:R32. 2006
    ..The effects of these drugs on oxidative stress were also assessed...
  11. ncbi request reprint Pulse oximetry and high-dose vasopressors: a comparison between forehead reflectance and finger transmission sensors
    Nicolas Nesseler
    Département d anesthésie réanimation 1, INSERM U991, Service de Réanimation Chirurgicale, Hopital Pontchaillou, Universite Rennes 1, 2 rue Henri Le Guilloux, 35033 Rennes Cedex 9, France
    Intensive Care Med 38:1718-22. 2012
    ..Forehead sensors using reflectance technology might be useful in these circumstances. We hypothesized that reflectance SpO(2) would be more accurate than finger SpO(2) in patients with severe shock...
  12. ncbi request reprint Incidence and risk factors of atrial fibrillation in a surgical intensive care unit
    Philippe Seguin
    Surgical Intensive Care Unit, Hopital Pontchaillou, Rennes, France
    Crit Care Med 32:722-6. 2004
    ..To evaluate the incidence and risks factors of atrial fibrillation (AF)...
  13. doi request reprint Long-term mortality and quality of life after septic shock: a follow-up observational study
    Nicolas Nesseler
    Département d anesthésie réanimation 1, INSERM U991, Service de Réanimation Chirurgicale, Hopital Pontchaillou, Universite Rennes 1, Rennes, France
    Intensive Care Med 39:881-8. 2013
    ..The aim of this study was to evaluate mortality and health-related quality of life (HRQOL) in survivors 6 months after an episode of septic shock...
  14. ncbi request reprint Effects of epinephrine compared with the combination of dobutamine and norepinephrine on gastric perfusion in septic shock
    Philippe Seguin
    Service de Réanimation Chirurgicale, Hopital de Pontchaillou, 2 Rue Henri Le Gailloux, Universite de Rennes I, 35033 Rennes Cedex, France
    Clin Pharmacol Ther 71:381-8. 2002
    ..The aim of the study was to compare epinephrine with the combination of dobutamine and norepinephrine on gastric perfusion in patients with septic shock...
  15. doi request reprint Effect of oropharyngeal povidone-iodine preventive oral care on ventilator-associated pneumonia in severely brain-injured or cerebral hemorrhage patients: a multicenter, randomized controlled trial
    Philippe Seguin
    1Département d Anesthésie Réanimation, Centre Hospitalier Universitaire, Rennes, France 2Inserm U991, Rennes, France 3Université Rennes 1, Rennes, France 4Service de Pharmacologie, Centre Hospitalier Universitaire, Rennes, France 5Centre d Investigation Clinique, INSERM 0203, Rennes, France 6Département d Anesthésie Réanimation, Centre Hospitalier Universitaire, Poitiers, France 7Inserm Eri 23, Poitiers, France 8Université Poitiers, Poitiers, France 9Département d Anesthésie Réanimation, Centre Hospitalier Universitaire, Nantes, France 10Département d Anesthésie Réanimation, Réanimation Chirurgicale, Centre Hospitalier Universitaire, Rouen, France 11Département d Anesthésie Réanimation, Centre Hospitalier Universitaire, Angers, France 12Service de Bactériologie Hygiène, Centre Hospitalier Universitaire, Rennes, France 13EA 1254 Microbiologie Risques Infectieux, Universite de Rennes 1, Rennes, France
    Crit Care Med 42:1-8. 2014
    ..To evaluate the efficacy and safety of oral care with povidone-iodine on the occurrence of ventilator-associated pneumonia in a high-risk population...
  16. pmc Clinical review: fever in septic ICU patients--friend or foe?
    Yoann Launey
    Service d anesthésie réanimation 1, Hopital Pontchaillou, 2 rue Henri Le Guilloux, 35000 Rennes, France
    Crit Care 15:222. 2011
    ..Finally, the treatment of fever by pharmacological and/or physical means is discussed with regards to their drawbacks, which argues for their careful use in septic patients in the absence of clinical relevance...
  17. ncbi request reprint Hub qualitative blood culture is useful for diagnosis of catheter-related infections in critically ill patients
    Michèle Tanguy
    Surgical Intensive Care Unit, Hopital Pontchaillou, 2 rue Henri Le Guilloux, 35033 Rennes Cedex 9, France
    Intensive Care Med 31:645-8. 2005
    ..To assess clinical safety and accuracy of qualitative blood culture drawn through the hub for ruling out catheter-related infection (CRI)...
  18. doi request reprint Effect of an anesthesia with propofol compared with desflurane on free radical production and liver function after partial hepatectomy
    Bruno Laviolle
    Service de Pharmacologie Clinique, Hopital de Pontchaillou, CHU de Rennes, Universite de Rennes 1, 35033 Rennes Cedex, France
    Fundam Clin Pharmacol 26:735-42. 2012
    ..Our study showed that in patients undergoing partial hepatectomy, propofol did not reduce MDA formation but seemed to display a protective effect on hepatic damages and liver function when compared to desflurane...
  19. ncbi request reprint The Accuracy of Transcutaneous PCO2 in Subjects With Severe Brain Injury: A Comparison With End-Tidal PCO2
    Sébastien Rosier
    Departement d Anesthesie Reanimation, Hopital Pontchaillou, Rennes
    Respir Care 59:1242-7. 2014
    ..We hypothesized that PtcCO2 would be more accurate than PETCO2 for monitoring PaCO2 in patients with severe brain injury...
  20. ncbi request reprint Effect of osmotherapy on optic nerve sheath diameter in patients with increased intracranial pressure
    Yoann Launey
    1 CHU de Rennes, Hopital Pontchaillou, Departement d Anesthesie Reanimation, Rennes, France
    J Neurotrauma 31:984-8. 2014
    ..001) and the CPP increased from 47 (50-60) to 66 (59-69) mmHg (p=0.003). The variations of ONSD appear to be an interesting parameter to evaluate the efficacy of osmotherapy for elevated ICP episodes in patients with acute brain injury...
  21. pmc Bench-to-bedside review: Routine postoperative use of the nasogastric tube - utility or futility?
    Michèle Tanguy
    Service d anesthésie réanimation 1, Hopital de Pontchaillou, rue Henri Le Guilloux, 35033 Rennes Cedex 9, France
    Crit Care 11:201. 2007
  22. ncbi request reprint Cerebral microdialysis effects of propofol versus midazolam in severe traumatic brain injury
    Michèle Tanguy
    Département d anesthésie réanimation 1, Hopital de Pontchaillou, Cedex, France
    J Neurotrauma 29:1105-10. 2012
    ..308), or glucose (time effect p=0.116, treatment effect p=0.088, time×treatment interaction p=0.235). These results do not support a difference between propofol and midazolam for sedation for the cerebral metabolic profile in severe TBI...
  23. ncbi request reprint Effect of oropharyngeal decontamination by povidone-iodine on ventilator-associated pneumonia in patients with head trauma
    Philippe Seguin
    Surgical Intensive Care Unit, INSERM U620, Hopital Pontchaillou, 2 rue Henri Le Guilloux, 35033 Rennes Cedex, France
    Crit Care Med 34:1514-9. 2006
    ..To evaluate the effect of a regular oropharyngeal application of povidone-iodine on the prevalence of ventilator-associated pneumonia in patients with severe head trauma...
  24. ncbi request reprint [Activated protein C treatment: experience about 23 patients in the operative period]
    A Maurice
    Service de Réanimation Chirurgicale, CHU Pontchaillou, 2, rue Henri Le Guillou, 35033 Rennes cedex 09, France
    Ann Fr Anesth Reanim 24:343-6. 2005
    ..To evaluate the use of activated C protein (ACP) in a Surgical Intensive Care Unit...
  25. ncbi request reprint Catecholamines induce an inflammatory response in human hepatocytes
    Caroline Aninat
    INSERM U620, Universite de Rennes 1, Rennes, France
    Crit Care Med 36:848-54. 2008
    ..As a prelude to clinical application, we tested the hypothesis that catecholamines could modulate the lipopolysaccharide-induced inflammatory response and function in human liver...
  26. ncbi request reprint The effects of small-dose ketamine on morphine consumption in surgical intensive care unit patients after major abdominal surgery
    Nicolas Guillou
    Surgical Intensive Care Unit, Hopital Pontchaillou, Rennes, France
    Anesth Analg 97:843-7. 2003
    ..05). We concluded that small doses of ketamine were a valuable adjunct to opioids in surgical intensive care unit patients after major abdominal surgery...
  27. pmc Estimation of the diameter and cross-sectional area of the internal jugular veins in adult patients
    Déborah Tartière
    Service d anesthésie réanimation 1, Universite de Rennes 1, Hopital Pontchaillou, 2 rue Henri Le Guilloux, 35000 Rennes, France
    Crit Care 13:R197. 2009
    ....
  28. ncbi request reprint Prevalence and impact of frailty on mortality in elderly ICU patients: a prospective, multicenter, observational study
    Pascale Le Maguet
    Departement d Anesthesie Reanimation, CHU Rennes, Rennes, France
    Intensive Care Med 40:674-82. 2014
    ..Frailty is a recent concept used for evaluating elderly individuals. Our study determined the prevalence of frailty in intensive care unit (ICU) patients and its impact on the rate of mortality...
  29. ncbi request reprint Reduced encephalopathy in pigs with ischemia-induced acute hepatic failure treated with a bioartificial liver containing alginate-entrapped hepatocytes
    Mireille Desille
    Institut National de la Santé et de La Recherche Mèdicale Unit 456, Detoxication et Reparation Tissulaire, Hopital Pontchaillou, Rennes, France
    Crit Care Med 30:658-63. 2002
    ..To analyze the effects of an extracorporeal bioartificial liver containing alginate bead-entrapped hepatocytes on pigs with ischemia-induced acute hepatic failure...
  30. ncbi request reprint Effects of price information on test ordering in an intensive care unit
    Philippe Seguin
    Service d Anesthésie Réanimation Chirurgicale 1, rue Henri Le Guilloux, Hopital de Pontchaillou, 35033 Rennes Cedex, France
    Intensive Care Med 28:332-5. 2002
    ..To determine if daily information on the price of common laboratory tests and chest X-ray could significantly influence test ordering by physicians and decrease the costs...
  31. ncbi request reprint Evaluation of a new semi-continuous cardiac output system in the intensive care unit
    P Seguin
    Service d Anesthesiologie Réanimation Chirurgicale 1, CHR U de Pontchaillou, Rennes, France
    Can J Anaesth 45:578-83. 1998
    ..The aim of this study was to compare the accuracy and reproducibility of this new device with conventional ice-bolus thermodilution cardiac output (BCO)...
  32. ncbi request reprint Evidence for the need of bedside accuracy of pulse oximetry in an intensive care unit
    P Seguin
    Service de Réanimation Chirurgicale, CHRU de Pontchaillou, Rennes, France
    Crit Care Med 28:703-6. 2000
    ....
  33. ncbi request reprint [Saccharomyces boulardii fungal sepsis: beware of the yeast]
    Sonia Piechno
    Can J Anaesth 54:245-6. 2007