Florent Sebbane

Summary

Country: France

Publications

  1. pmc Role of the Yersinia pestis yersiniabactin iron acquisition system in the incidence of flea-borne plague
    Florent Sebbane
    Equipe Peste et Yersinia pestis, Centre d Infection et d Immunité de Lille, Institut Pasteur de Lille, Lille, France
    PLoS ONE 5:e14379. 2010
  2. doi request reprint Inheritance of the lysozyme inhibitor Ivy was an important evolutionary step by Yersinia pestis to avoid the host innate immune response
    Anne Derbise
    Equipe Peste et Yersinia pestis, Inserm U1019, Paris, France
    J Infect Dis 207:1535-43. 2013
  3. pmc Efficacy of ciprofloxacin-gentamicin combination therapy in murine bubonic plague
    Nadine Lemaitre
    Laboratoire de Bacteriologie Hygiene, Centre Hospitalier Universitaire, Lille, France
    PLoS ONE 7:e52503. 2012
  4. pmc The Yersinia pestis caf1M1A1 fimbrial capsule operon promotes transmission by flea bite in a mouse model of bubonic plague
    Florent Sebbane
    Institut National de la Sante et de la Recherche Medicale, U801, Institut Pasteur de Lille, Lille, France
    Infect Immun 77:1222-9. 2009
  5. pmc New insights into how Yersinia pestis adapts to its mammalian host during bubonic plague
    Elizabeth Pradel
    Equipe Peste et Yersinia pestis INSERM U1019, Lille, France Centre National de la Recherche Scientifique UMR8204, Lille, France Institut Pasteur de Lille, Centre d Infection et d Immunité de Lille, Lille, France Univ Lille Nord de France, Lille, France UDSL, Centre d Infection et d Immunité de Lille, Lille, France
    PLoS Pathog 10:e1004029. 2014
  6. pmc Evaluation of the Role of the opgGH Operon in Yersinia pseudotuberculosis and Its Deletion during the Emergence of Yersinia pestis
    Kevin Quintard
    Plague and Yersinia pestis Group, Inserm U1019, Lille, France Centre National de la Recherche Scientifique UMR8204, Lille, France Institut Pasteur de Lille, Centre d Infection et d Immunité de Lille, Lille, France Université Lille Nord de France, Lille, France Université du Droit et de la Santé de Lille, Centre d Infection et d Immunité de Lille, Lille, France Unité de Glycobiologie Structurale et Fonctionnelle, UMR CNRS 8576, Universite des Sciences et Technologies de Lille, Université de Lille Nord de France, Villeneuve d Ascq, France
    Infect Immun 83:3638-47. 2015
  7. doi request reprint Autophagosomes can support Yersinia pseudotuberculosis replication in macrophages
    Kevin Moreau
    Cellular Microbiology of Infectious Pathogens, Center of Infection and Immunity of Lille, Institut Pasteur de Lille, Lille, France
    Cell Microbiol 12:1108-23. 2010
  8. pmc TLR5 signaling stimulates the innate production of IL-17 and IL-22 by CD3(neg)CD127+ immune cells in spleen and mucosa
    Laurye Van Maele
    Institut Pasteur de Lille, Centre d Infection et d Immunité de Lille, France
    J Immunol 185:1177-85. 2010
  9. pmc Functional and structural analysis of HicA3-HicB3, a novel toxin-antitoxin system of Yersinia pestis
    Sabrina Bibi-Triki
    Equipe Peste et Yersinia pestis, Inserm U1019, Lille, France CNRS UMR 8204, Lille, France Institut Pasteur de Lille, Centre d Infection et d Immunité, Lille, France Université Lille Nord de France, Lille, France UDSL, Lille, France
    J Bacteriol 196:3712-23. 2014
  10. pmc Superantigenic Yersinia pseudotuberculosis Induces the Expression of Granzymes and Perforin by CD4+ T Cells
    Agathe Goubard
    Universite Lille Nord de France, Inserm U1019, CNRS UMR 8204, and Institut Pasteur de Lille, Center for Infection and Immunity of Lille, Lille, France
    Infect Immun 83:2053-64. 2015

Collaborators

Detail Information

Publications11

  1. pmc Role of the Yersinia pestis yersiniabactin iron acquisition system in the incidence of flea-borne plague
    Florent Sebbane
    Equipe Peste et Yersinia pestis, Centre d Infection et d Immunité de Lille, Institut Pasteur de Lille, Lille, France
    PLoS ONE 5:e14379. 2010
    ..The results provide new evidence that primary septicemic plague is a distinct clinical entity and suggest that unusual forms of plague may be caused by atypical Y. pestis strains...
  2. doi request reprint Inheritance of the lysozyme inhibitor Ivy was an important evolutionary step by Yersinia pestis to avoid the host innate immune response
    Anne Derbise
    Equipe Peste et Yersinia pestis, Inserm U1019, Paris, France
    J Infect Dis 207:1535-43. 2013
    ..The involvement of both inhibitors in virulence remains subject to debate...
  3. pmc Efficacy of ciprofloxacin-gentamicin combination therapy in murine bubonic plague
    Nadine Lemaitre
    Laboratoire de Bacteriologie Hygiene, Centre Hospitalier Universitaire, Lille, France
    PLoS ONE 7:e52503. 2012
    ..Moreover, draining lymph nodes may serve as a reservoir for the continued release of Y. pestis into the blood - even after five days of intravenous antibiotic treatment...
  4. pmc The Yersinia pestis caf1M1A1 fimbrial capsule operon promotes transmission by flea bite in a mouse model of bubonic plague
    Florent Sebbane
    Institut National de la Sante et de la Recherche Medicale, U801, Institut Pasteur de Lille, Lille, France
    Infect Immun 77:1222-9. 2009
    ..pestis strains in plague foci may be necessary. The results also highlight the importance of studying Y. pestis pathogenesis in the natural context of arthropod-borne transmission...
  5. pmc New insights into how Yersinia pestis adapts to its mammalian host during bubonic plague
    Elizabeth Pradel
    Equipe Peste et Yersinia pestis INSERM U1019, Lille, France Centre National de la Recherche Scientifique UMR8204, Lille, France Institut Pasteur de Lille, Centre d Infection et d Immunité de Lille, Lille, France Univ Lille Nord de France, Lille, France UDSL, Centre d Infection et d Immunité de Lille, Lille, France
    PLoS Pathog 10:e1004029. 2014
    ..Our results suggest that (i) intracellular survival during the early stage of infection is important for plague and (ii) horizontal gene transfer was crucial in the acquisition of this ability...
  6. pmc Evaluation of the Role of the opgGH Operon in Yersinia pseudotuberculosis and Its Deletion during the Emergence of Yersinia pestis
    Kevin Quintard
    Plague and Yersinia pestis Group, Inserm U1019, Lille, France Centre National de la Recherche Scientifique UMR8204, Lille, France Institut Pasteur de Lille, Centre d Infection et d Immunité de Lille, Lille, France Université Lille Nord de France, Lille, France Université du Droit et de la Santé de Lille, Centre d Infection et d Immunité de Lille, Lille, France Unité de Glycobiologie Structurale et Fonctionnelle, UMR CNRS 8576, Universite des Sciences et Technologies de Lille, Université de Lille Nord de France, Villeneuve d Ascq, France
    Infect Immun 83:3638-47. 2015
    ..The opgGH operon was presumably then lost because OpgH-dependent cell size control became unnecessary...
  7. doi request reprint Autophagosomes can support Yersinia pseudotuberculosis replication in macrophages
    Kevin Moreau
    Cellular Microbiology of Infectious Pathogens, Center of Infection and Immunity of Lille, Institut Pasteur de Lille, Lille, France
    Cell Microbiol 12:1108-23. 2010
    ..pseudotuberculosis hijacks the autophagy pathway for its replication and also opens up new opportunities for deciphering the molecular basis of the host cell signalling response to intracellular Yersinia infection...
  8. pmc TLR5 signaling stimulates the innate production of IL-17 and IL-22 by CD3(neg)CD127+ immune cells in spleen and mucosa
    Laurye Van Maele
    Institut Pasteur de Lille, Centre d Infection et d Immunité de Lille, France
    J Immunol 185:1177-85. 2010
    ..These data define that TLR-induced activation of CD3(neg)CD127(+) cells and production of Th17-related cytokines may be crucial for the early defenses against pathogen invasion of host tissues...
  9. pmc Functional and structural analysis of HicA3-HicB3, a novel toxin-antitoxin system of Yersinia pestis
    Sabrina Bibi-Triki
    Equipe Peste et Yersinia pestis, Inserm U1019, Lille, France CNRS UMR 8204, Lille, France Institut Pasteur de Lille, Centre d Infection et d Immunité, Lille, France Université Lille Nord de France, Lille, France UDSL, Lille, France
    J Bacteriol 196:3712-23. 2014
    ..HicA3 is monomeric and folds as a double-stranded-RNA-binding domain. The HicB3 N-terminal domain occludes the HicA3 active site, whereas its C-terminal domain folds as a ribbon-helix-helix DNA-binding motif. ..
  10. pmc Superantigenic Yersinia pseudotuberculosis Induces the Expression of Granzymes and Perforin by CD4+ T Cells
    Agathe Goubard
    Universite Lille Nord de France, Inserm U1019, CNRS UMR 8204, and Institut Pasteur de Lille, Center for Infection and Immunity of Lille, Lille, France
    Infect Immun 83:2053-64. 2015
    ..Our results demonstrate that YPM activates a potentially hepatotoxic CD4(+) T cell population. ..
  11. doi request reprint Protection against Yersinia pseudotuberculosis infection conferred by a Lactococcus lactis mucosal delivery vector secreting LcrV
    Catherine Daniel
    Laboratoire des Bactéries Lactiques et Immunité des Muqueuses, Institut Fédératif de Recherche 142, Institut Pasteur de Lille, Lille F 59021, France
    Vaccine 27:1141-4. 2009
    ..pseudotuberculosis infections. This constitutes the first proof of principle for a novel anti-Yersinia mucosal vaccination strategy using recombinant lactic acid bacteria...