Research Topics
| Marie SarazinSummaryCountry: France Publications
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Detail Information
Publications
The amnestic syndrome of hippocampal type in Alzheimer's disease: an MRI studyMarie Sarazin
CRICM UPMC Inserm UMR 975 Pitié Salpêtrière Hospital, Paris, France
J Alzheimers Dis 22:285-94. 2010..In AD, the FCSRT may be considered as a useful clinical marker of memory disorders due to medial temporal damage, specially the CA1 field of the hippocampus...
Frontal assessment battery and differential diagnosis of frontotemporal dementia and Alzheimer diseaseAndrea Slachevsky
Institut National de la Santé et de la Récherche Médicale E 007 and Fédération de Neurologie, Hopital de la Salpetriere, Paris, France
Arch Neurol 61:1104-7. 2004..The Frontal Assessment Battery (FAB) has previously been validated in diseases associated with a frontal lobe dysfunction...- [A guide to diagnosis of Alzheimer's disease]Marie Sarazin
Centre de mémoire de ressource et de recherche d Ile de France, centre de neuropsychologie et du langage et unité Inserm U 610, Fédération des Maladies du Système Nerveux, groupe hospitalier La Pitié La Salpêtrière, 75651 Paris
Rev Prat 55:1879-90. 2005..Standard biological parameters are normal. According to the context of occurrences of the disease or to the existence of atypical clinical or radiological changes, additional investigations can be proposed... - Amnestic syndrome of the medial temporal type identifies prodromal AD: a longitudinal studyM Sarazin
INSERM U 610 and Centre des Maladies Cognitives et Comportementales, Hopital de la Salpetriere, Paris, France
Neurology 69:1859-67. 2007..To compare the power of tests assessing different cognitive domains for the identification of prodromal Alzheimer disease (AD) among patients with mild cognitive impairment (MCI)... 
Early detection of Alzheimer's disease: new diagnostic criteriaBruno Dubois
INSERM UPMC UMRS 975, Federation of Neurology, APHP, Salpetriere Hospital, University Paris 6, Paris, France
Dialogues Clin Neurosci 11:135-9. 2009..Accordingly, new criteria for the diagnosis have been proposed that capture both the prodromal and the more advanced dementia stages of the disease in the same diagnostic framework...- Clinical and research diagnostic criteria for Alzheimer's diseaseMarie Sarazin
Universite Pierre et Marie Curie Paris 6, Centre de Recherche de l Institut du Cerveau et de la Moelle Epiniere, UMR S975, 47 83 boulevard de l Hopital, 75013 Paris, France
Neuroimaging Clin N Am 22:23-32,viii. 2012..The core clinical criteria continue to be the cornerstone of the diagnosis in clinical practice, but biomarker evidence is expected to enhance the specificity for the diagnosis of Alzheimer's disease... - Similar amyloid-β burden in posterior cortical atrophy and Alzheimer's diseaseLeonardo Cruz de Souza
Fédération des Maladies du Système Nerveux, Research and Resource Memory Centre, Pavillon Jean Lhermitte, Hopital de la Salpetriere, 47 Boulevard de l Hopital, 75013 Paris, France
Brain 134:2036-43. 2011.... - Visuospatial deficits in posterior cortical atrophy: structural and functional correlatesKatia Andrade
INSERM UMR_S 975, Centrede Recherche de l Institut du Cerveau et de la Moelle épinière CRICM, Paris, France
J Neurol Neurosurg Psychiatry 83:860-3. 2012..To determine the neural substrates of biased spatial orienting in posterior cortical atrophy (PCA) by using a combined structural and functional neuroimaging approach... - Cerebrospinal fluid biomarkers in the differential diagnosis of Alzheimer's disease from other cortical dementiasLeonardo Cruz de Souza
CRicm, UPMC Univ Paris 06, Pitie Salpetriere Hospital, Paris, France
J Neurol Neurosurg Psychiatry 82:240-6. 2011..Additionally, biomarkers may be useful for identifying patients with atypical phenotypic presentations of AD, such as posterior cortical atrophy (PCA) and primary progressive non-fluent or logopenic aphasia (PNFLA)... - Distinct patterns of antiamyloid-β antibodies in typical and atypical Alzheimer diseaseGuillaume Dorothee
INSERM, UMRS938, St Antoine Hospital, Paris, France
Arch Neurol 69:1181-5. 2012..To compare serum antiamyloid-β (Aβ) antibodies in typical and atypical Alzheimer disease (AD)... - CSF tau markers are correlated with hippocampal volume in Alzheimer's diseaseLeonardo C de Souza
Universite Pierre et Marie Curie Paris 6, Centre de Recherche de l Institut du Cerveau et de Moelle épinière, UMR S975, Paris, France
Neurobiol Aging 33:1253-7. 2012..The CSF tau and P-tau levels, but not the CSF Aβ(42) level, correlated with HV, suggesting that CSF tau markers reflect the neuronal loss associated with the physiopathological process of AD... - Social Cognition and Emotional Assessment differentiates frontotemporal dementia from depressionMaxime Bertoux
Université Pierre et Marie Curie UPMC Paris 6, Paris, France
J Neurol Neurosurg Psychiatry 83:411-6. 2012..Its diagnosis remains a clinical challenge, and depression is one of the main causes of misdiagnoses due to the prevalence of apathy in bvFTD... - Distinct brain perfusion pattern associated with CSF biomarkers profile in primary progressive aphasiaAurélie Kas
Alzheimerb s Institute, AP HP, Pitie Salpetriere Hospital, Paris, France
J Neurol Neurosurg Psychiatry 83:695-8. 2012..Single photon emission computed tomography (SPECT) was used to investigate brain hypoperfusion differences among PPA subtypes according to their CSF AD profiles... - Support vector machine-based classification of Alzheimer's disease from whole-brain anatomical MRIBenoît Magnin
UMR S 678, INSERM, Paris, France
Neuroradiology 51:73-83. 2009.... - Poor creativity in frontotemporal dementia: a window into the neural bases of the creative mindLeonardo Cruz de Souza
Universite Pierre et Marie Curie Paris 6, Centre de Recherche de l Institut du Cerveau et de la Moelle Epiniere, UMR S975, Paris, France
Neuropsychologia 48:3733-42. 2010..Damage to the PFC is expected to impair creativity. Yet, previous works suggested the emergence of artistic talent in patients with frontotemporal lobar degeneration (FTLD), which was interpreted as increased creativity... - Brain perfusion SPECT with an automated quantitative tool can identify prodromal Alzheimer's disease among patients with mild cognitive impairmentMarie Odile Habert
Universite Pierre et Marie Curie Paris 6, INSERM, UMR S 678, Paris, F 75013, France
Neurobiol Aging 32:15-23. 2011..e., prodromal AD, by an automated quantitative tool combining brain perfusion single-photon emission computed tomography (SPECT) images and memory tests scores in order to be applied in clinical practice... - Long-standing prion dementia manifesting as posterior cortical atrophyRaphaël Depaz
Assistance Publique Hopitaux de Paris, Departement de Neurologie, Paris, France
Alzheimer Dis Assoc Disord 26:289-92. 2012..Two cases exhibited mixed prion and Aβ pathology. The differential diagnosis with Alzheimer disease is discussed... - Brain perfusion SPECT correlates with CSF biomarkers in Alzheimer's diseaseMarie Odile Habert
Universite Pierre et Marie Curie Paris 6, INSERM, UMR S 678, 75013, Paris, France
Eur J Nucl Med Mol Imaging 37:589-93. 2010.... - Clinical investigations in primary careLeonardo Cruz de Souza
Research and Resource Memory Centre, INSERM UMR S 610, Universite Pierre et Marie Curie Paris 06, Pitie Salpetriere Hospital, Paris, France
Front Neurol Neurosci 24:1-11. 2009..Other medical, neurological, or psychiatric disorders which could account for the impairment in memory and related symptoms must be always investigated... - Magnetic resonance imaging of Alzheimer's diseaseStephane Lehericy
Department of Neuroradiology, Universite Pierre et Marie Curie Paris 6, Groupe Hospitalier Pitie Salpetriere, 47 83 boulevard de l Hopital, Paris 75651, Cedex 13, France
Eur Radiol 17:347-62. 2007..This review focuses on markers of macro- and microstructural, perfusion, diffusion and metabolic MR imaging and spectroscopy in AD... - Neural correlates of cognitive impairment in posterior cortical atrophyAurélie Kas
Service de Medecine Nucleaire, GH Pitié Salpétrière, 47 83, Boulevard de l Hopital, 75651 Paris Cedex 13, France
Brain 134:1464-78. 2011.... - Neuroimaging in dementiasLeonardo Cruz de Souza
Alzheimer and Memory Institute Research and Resource Memory Centre, AP HP, Paris, France
Curr Opin Psychiatry 25:473-9. 2012..To critically review data on the use of neuroimaging tools in the clinical diagnostic investigation of dementias... - Visual neglect in posterior cortical atrophyKatia Andrade
INSERM UMR_S 975, Centre de Recherche de l Institut du Cerveau et de Moelle épinière, Cognition, neuro imagerie et maladies du cerveau, Paris, France
BMC Neurol 10:68. 2010..In this prospective study, we aimed at establishing the side, the frequency and the severity of visual neglect, visual extinction, and primary visual field defects in an unselected sample of PCA patients... - Revising the definition of Alzheimer's disease: a new lexiconBruno Dubois
Pierre and Marie Curie University, Research Centre of the Institute of the Brain and Spinal Cord, UMR, AP HP, Pitié Salpêtrière Hospital Group, Paris, France
Lancet Neurol 9:1118-27. 2010..The cornerstone of this lexicon is to consider AD solely as a clinical and symptomatic entity that encompasses both predementia and dementia phases... - Metabolic correlates of behavioral and affective disturbances in frontal lobe pathologiesMarie Sarazin
Inserm E 007 and Federation of Neurology, , Paris, France
J Neurol 250:827-33. 2003.... - [Alzheimer's disease: therapeutic perspectives]Bruno Dubois
Centre des Maladies Cognitives et Comportementales et Inserm U 610, Hopital de la Salpetriere, 47, Boulevard de l Hopital, 75013 Paris
Bull Acad Natl Med 192:333-42; discussion 343-4. 2008..Future treatments may be curative, acting specifically on the amyloid cascade. Secretase inhibitors and immunotherapy are in the pipeline. Trials will begin within a few months and will open up new perspectives... - Fronto-temporal lobar degeneration: neuropathology in 60 casesDanielle Seilhean
Centre de Recherche de l Institut du Cerveau et de la Moelle Epiniere, Inserm UMR_S975, CNRS UMR7225, Groupe Hospitalier Pitie Salpetriere, AP HP and UPMC Sorbonne Universités, Paris, France
J Neural Transm 118:753-64. 2011..The prevalence of the different types of FTD is tightly linked to the recruitment. This series was enriched in motor neuron disease (explaining the overall predominance of type 2 TDP inclusions)... - Procedural learning and striatofrontal dysfunction in Parkinson's diseaseMarie Sarazin
, Paris, France
Mov Disord 17:265-73. 2002..These results confirm the involvement of striatofrontal circuits in procedural learning and indicate that the intervention of the frontal network may depend on the characteristics of the task... - Implicit and explicit emotional memory for melodies in Alzheimer's disease and depressionNolwenn Quoniam
Laboratoire de Psychologie Clinique et de Psychopathologie, Institut de Psychologie, Universite Paris 5, Paris, France
Ann N Y Acad Sci 999:381-4. 2003..Results showed that unlike Alzheimer's patients, depressed patients were unable to develop a positive affective bias of judgment for previously heard melodies... - Laboratory investigations and treatment in frontotemporal dementiaFlorence Pasquier
CHRU Clinique Neurologie, Lille. France
Ann Neurol 54:S32-5. 2003 - Relationship between attentional performance and corpus callosum morphometry in patients with Alzheimer's diseaseAgnès A Dorion
Laboratoire de Développement Normal et Troublé, Universite Paul Valery, route de Mende, 34199 Montpellier Cedex 5, France
Neuropsychologia 40:946-56. 2002..Moreover, these patients with probable AD seem heterogeneous for performances in the attentional test of the CANTAB and for callosal atrophies...