Remy Sapin

Summary

Country: France

Publications

  1. ncbi request reprint The interference of insulin antibodies in insulin immunometric assays
    Remy Sapin
    Unite d Analyses Endocriniennes, CNRS UMR 7004, Universite Louis Pasteur, Faculte de Medecine, Strasbourg, France
    Clin Chem Lab Med 40:705-8. 2002
  2. ncbi request reprint Serum thyroxine binding capacity-dependent bias in five free thyroxine immunoassays: assessment with serum dilution experiments and impact on diagnostic performance
    R Sapin
    Laboratoire Universitaire de Biophysique, Unite d Analyses Endocriniennes, Faculte de Medecine, Universite Louis Pasteur, CNRS UPRES A 7004, F 67085 Cedex, Strasbourg, France
    Clin Biochem 34:367-71. 2001
  3. ncbi request reprint Free thyroxine measured with equilibrium dialysis and nine immunoassays decreases in late pregnancy
    Remy Sapin
    Laboratoire de Biophysique, ULP CNRS UMR 7004, Hopital Civil, 67091 Strasbourg Cedex, France
    Clin Lab 50:581-4. 2004
  4. ncbi request reprint Misleading high thyrotropin results obtained with a two-site immunometric assay involving a chimeric antibody
    Remy Sapin
    Unité Mixte de recherche 7004, Université Louis Pasteur Centre National de la Recherche Scientifique, Faculte de Medecine, Strasbourg Cedex, France
    Clin Chem 50:946-8. 2004
  5. ncbi request reprint Increased sensitivity of a new assay for anti-thyroglobulin antibody detection in patients with autoimmune thyroid disease
    Remy Sapin
    Laboratoire Universitaire de Biophysique, Unite d Analyses Endocriniennes, ULP CNRS UMR 7004, Faculte de Medecine, 67085 Strasbourg Cedex, France
    Clin Biochem 36:611-6. 2003
  6. ncbi request reprint Free thyroxine measured by equilibrium dialysis and nine immunoassays in sera with various serum thyroxine-binding capacities
    Remy Sapin
    Laboratoire Universitaire de Biophysique, Unite d Analyses Endocriniennes, Université Louis Pasteur Centre National de la Recherche Scientifique Unité Mixte de Recherche 7004, Faculte de Medecine, 67085 Strasbourg Cedex, France
    Clin Chem 49:1531-5. 2003
  7. ncbi request reprint [Thyroxine (T4) and tri-iodothyronine (T3) determinations: techniques and value in the assessment of thyroid function]
    R Sapin
    Unite d Analyses Endocriniennes, Laboratoire Universitaire de Biophysique, CNRS ULP UMR 7004, Faculte de Medecine, Strasbourg
    Ann Biol Clin (Paris) 61:411-20. 2003
  8. ncbi request reprint Insulin assays: previously known and new analytical features
    Remy Sapin
    Unite d Analyses Endocriniennes, Institut de Physique Biologique, CNRS ULP UMR 7004, Faculte de Medecine, Strasbourg, France
    Clin Lab 49:113-21. 2003
  9. ncbi request reprint Macroprolactin detection by precipitation with protein A-sepharose: a rapid screening method compared with polyethylene glycol precipitation
    Remy Sapin
    Laboratoire Universitaire de Biophysique, Unite d Analyses Endocriniennes, ULP CNRS UMR 7004, Faculte de Medecine, Strasbourg, France
    Clin Chem 49:502-5. 2003
  10. ncbi request reprint Free prolactin determinations in hyperprolactinemic men with suspicion of macroprolactinemia
    Remy Sapin
    Laboratoire Universitaire de Biophysique, Unite d Analyses Endocriniennes, CNRS UPRES A7004, Faculte de Medecine, Universite Louis Pasteur, 67085 Strasbourg Cedex, France
    Clin Chim Acta 316:33-41. 2002

Collaborators

  • Jean Louis Schlienger
  • Arnaud Agin
  • M Said Ghandour
  • Nelly Boehm
  • Bernard Goichot
  • Laura Adela Harsan
  • Nathalie Jeandidier
  • Daniel Grucker
  • Nathalie Parizel
  • Blandine Guignard
  • Jerome Steibel
  • Patrick Poulet
  • Anita Zaremba
  • Robert H Miller
  • Gerard Chabrier
  • Françoise Gasser
  • Michel Pinget
  • Marie Sophie Busch-Brafin
  • Sylvie Boullu

Detail Information

Publications14

  1. ncbi request reprint The interference of insulin antibodies in insulin immunometric assays
    Remy Sapin
    Unite d Analyses Endocriniennes, CNRS UMR 7004, Universite Louis Pasteur, Faculte de Medecine, Strasbourg, France
    Clin Chem Lab Med 40:705-8. 2002
    ..This study underlines the interference of insulin antibodies in insulin immunometric assays and the importance of assessing an insulin immunometric assay for sensitivity towards the presence of these antibodies...
  2. ncbi request reprint Serum thyroxine binding capacity-dependent bias in five free thyroxine immunoassays: assessment with serum dilution experiments and impact on diagnostic performance
    R Sapin
    Laboratoire Universitaire de Biophysique, Unite d Analyses Endocriniennes, Faculte de Medecine, Universite Louis Pasteur, CNRS UPRES A 7004, F 67085 Cedex, Strasbourg, France
    Clin Biochem 34:367-71. 2001
    ..The exhibited bias is confronted with clinical results from previous studies to evaluate its impact on FT(4) determination in sera with various sBC...
  3. ncbi request reprint Free thyroxine measured with equilibrium dialysis and nine immunoassays decreases in late pregnancy
    Remy Sapin
    Laboratoire de Biophysique, ULP CNRS UMR 7004, Hopital Civil, 67091 Strasbourg Cedex, France
    Clin Lab 50:581-4. 2004
    ..Method-specific reference intervals should be determined during pregnancy to be in a position to quantify not only hypothyroidism but also hyperthyroidism and to adjust an appropriate T4 treatment...
  4. ncbi request reprint Misleading high thyrotropin results obtained with a two-site immunometric assay involving a chimeric antibody
    Remy Sapin
    Unité Mixte de recherche 7004, Université Louis Pasteur Centre National de la Recherche Scientifique, Faculte de Medecine, Strasbourg Cedex, France
    Clin Chem 50:946-8. 2004
  5. ncbi request reprint Increased sensitivity of a new assay for anti-thyroglobulin antibody detection in patients with autoimmune thyroid disease
    Remy Sapin
    Laboratoire Universitaire de Biophysique, Unite d Analyses Endocriniennes, ULP CNRS UMR 7004, Faculte de Medecine, 67085 Strasbourg Cedex, France
    Clin Biochem 36:611-6. 2003
    ..To verify the cut-off values and to determine the clinical sensitivity of antithyroglobulin (TgAb) determinations using our routine RIA and the new electrochemiluminescent Elecsys assay...
  6. ncbi request reprint Free thyroxine measured by equilibrium dialysis and nine immunoassays in sera with various serum thyroxine-binding capacities
    Remy Sapin
    Laboratoire Universitaire de Biophysique, Unite d Analyses Endocriniennes, Université Louis Pasteur Centre National de la Recherche Scientifique Unité Mixte de Recherche 7004, Faculte de Medecine, 67085 Strasbourg Cedex, France
    Clin Chem 49:1531-5. 2003
  7. ncbi request reprint [Thyroxine (T4) and tri-iodothyronine (T3) determinations: techniques and value in the assessment of thyroid function]
    R Sapin
    Unite d Analyses Endocriniennes, Laboratoire Universitaire de Biophysique, CNRS ULP UMR 7004, Faculte de Medecine, Strasbourg
    Ann Biol Clin (Paris) 61:411-20. 2003
    ....
  8. ncbi request reprint Insulin assays: previously known and new analytical features
    Remy Sapin
    Unite d Analyses Endocriniennes, Institut de Physique Biologique, CNRS ULP UMR 7004, Faculte de Medecine, Strasbourg, France
    Clin Lab 49:113-21. 2003
    ..Immunometric assays have also improved the sensitivity and reproducibility of free insulin measurements. Standardization of insulin immunoassays is still called for...
  9. ncbi request reprint Macroprolactin detection by precipitation with protein A-sepharose: a rapid screening method compared with polyethylene glycol precipitation
    Remy Sapin
    Laboratoire Universitaire de Biophysique, Unite d Analyses Endocriniennes, ULP CNRS UMR 7004, Faculte de Medecine, Strasbourg, France
    Clin Chem 49:502-5. 2003
  10. ncbi request reprint Free prolactin determinations in hyperprolactinemic men with suspicion of macroprolactinemia
    Remy Sapin
    Laboratoire Universitaire de Biophysique, Unite d Analyses Endocriniennes, CNRS UPRES A7004, Faculte de Medecine, Universite Louis Pasteur, 67085 Strasbourg Cedex, France
    Clin Chim Acta 316:33-41. 2002
    ..The Elecsys prolactin (PRL) assay reacts more strongly with macroprolactin than the Centaur PRL assay. We evaluated Elecsys direct and free PRL measurements vs. Centaur direct PRL measurements, in sera with and without macroprolactin...
  11. ncbi request reprint Use of insulin immunoassays in clinical studies involving rapid-acting insulin analogues: Bi-insulin IRMA preliminary assessment
    Arnaud Agin
    Faculte de Medecine, Universite Louis Pasteur, Centre National de la Recherche Scientifique, Unité Mixte de recherche 7004, Institut de Physique Biologique, Strasbourg, France
    Clin Chem Lab Med 44:1379-82. 2006
    ..The aims of our study were to compare cross-reactivities of RI and RAAs in buffer and in serum and to investigate insulin immunoassay pitfalls...
  12. ncbi request reprint Comparison of antigenicity of Hoechst 21PH insulin using either implantable intraperitoneal pump or subcutaneous external pump infusion in type 1 diabetic patients
    Nathalie Jeandidier
    Department of Endocrinology and Diabetes, University Hospital, Strasbourg, France
    Diabetes Care 25:84-8. 2002
    ..AIA levels were measured by radioimmunoassay (RIA) or enzyme-linked immunosorbent assay (ELISA) before starting patients on Hoe21PH and again after 3 and 6 months...
  13. doi request reprint Recovery from chronic demyelination by thyroid hormone therapy: myelinogenesis induction and assessment by diffusion tensor magnetic resonance imaging
    Laura Adela Harsan
    UMR 7191, Laboratoire d Imagerie et de Neurosciences Cognitives, Faculte de Medecine, Université Louis Pasteur and Centre National de la Recherche Scientifique, 67085 Strasbourg, France
    J Neurosci 28:14189-201. 2008
    ..Our findings establish a role for T(3) as an inducer of oligodendrocyte progenitor cells in adult mouse brain following chronic demyelination...
  14. doi request reprint Subclinical hyperthyroidism: considerations in defining the lower limit of the thyrotropin reference interval
    Bernard Goichot
    Service de Medecine interne et nutrition, Hopital de Hautepierre, Hopitaux Universitaires de Strasbourg, Strasbourg, France
    Clin Chem 55:420-4. 2009
    ..Recent recommendations regarding subclinical thyroid dysfunction give different advice about its management, depending on whether the TSH concentration is <0.1 mIU/L or 0.1-0.4 mIU/L...