Raphaëlle L Santarelli
- Processed meat and colorectal cancer: a review of epidemiologic and experimental evidenceRaphaëlle L Santarelli
UMR1089 INRA ENVT Xénobiotiques, Universite de Toulouse, Ecole Nationale Veterinaire, Toulouse, France
Nutr Cancer 60:131-44. 2008..Nitrosation might increase the toxicity of heme in cured products. Solving this puzzle is a challenge that would permit to reduce cancer load by changing the processes rather than by banning processed meat...
- Calcium and α-tocopherol suppress cured-meat promotion of chemically induced colon carcinogenesis in rats and reduce associated biomarkers in human volunteersFabrice H F Pierre
Universite de Toulouse, French National Institute for Agricultural Research, Joint Research Unit 1331 Xénobiotiques, Toulouse, France FHFP, OCBM, RLS, St, NN, FG, MA, Jd, and DEC the French Pork and Pig Institute Institut du Porc, Paris, France RLS and J LV the INRA, UMR 1019, Human Nutrition Unit, Research Center for Human Nutrition Auvergne, Clermont Ferrrand, France NM, DA, and NC the University hospital Clermont Ferrand, Service de Nutrition, Clermont Ferrrand, France NM and NC the Eppley Institute for Research in Cancer, University of Nebraska Medical Center, Omaha, NE SSM and the Department of Food and Nutritional Sciences, University of Reading, Reading, United Kingdom GCGK
Am J Clin Nutr 98:1255-62. 2013..Processed meat intake has been associated with increased colorectal cancer risk. We have shown that cured meat promotes carcinogen-induced preneoplastic lesions and increases specific biomarkers in the colon of rats...
- Calcium inhibits promotion by hot dog of 1,2-dimethylhydrazine-induced mucin-depleted foci in rat colonRaphaëlle L Santarelli
Universite de Toulouse, ENVT, INRA, UMR1331 Toxalim, BP 87614, 23 Ch des Capelles, F 31076, Toulouse, France IFIP Institut Français du Porc, 149 rue de Bercy, F 75595, Paris Cedex 12, France
Int J Cancer 133:2533-41. 2013..2.3 ± 1.4, respectively, p < 0.05). This is the first experimental evidence that a widely consumed processed meat promotes colon carcinogenesis in rats. It also shows that dietary prevention of this detrimental effect is possible...
- Freeze-dried ham promotes azoxymethane-induced mucin-depleted foci and aberrant crypt foci in rat colonFabrice H F Pierre
Universite de Toulouse, INRA ENVT, Toulouse, France
Nutr Cancer 62:567-73. 2010..Freeze-dried cooked ham can promote colon carcinogenesis in a rodent model. Hemin, but not hemoglobin, mimicked ham effect on early biochemical markers associated with carcinogenesis...