- [Auditory perception and language: functional imaging of speech sensitive auditory cortex]Y Samson
CEA, DRM, Service Hospitalier Frederic Joliot, Orsay, France
Rev Neurol (Paris) 157:837-46. 2001....
- [Thrombolytic treatment of cerebral infarction]Yves Samson
Groupe hospitalier La Pitié La Salpêtrière 75651 Paris
Rev Prat 52:1977-9. 2002
- Accurate prediction of postoperative outcome in mesial temporal lobe epilepsy: a study using positron emission tomography with 18fluorodeoxyglucoseS Dupont
Service Hospitalier Frederic Joliot, Commissariat a l Energie Atomique, 91401 Orsay Cedex, France
Arch Neurol 57:1331-6. 2000..Recent studies suggest that positron emission tomography may be a reliable predictive indicator of clinical outcome following surgical treatment for epilepsy...
- Temporal lobe dysfunction in childhood autism: a PET study. Positron emission tomographyM Zilbovicius
Service Hospitalier Frederic Joliot, Direction des Sciences du Vivant, Département de Recherche, Commisariat à l Energie Atomique, Tours, France
Am J Psychiatry 157:1988-93. 2000..The authors reasoned that early methods may have been insensitive to such dysfunction, which may now be detectable with improved technology...
- In vivo imaging of muscarinic cholinergic receptors in temporal lobe epilepsy with a new PET tracer: [76Br]4-bromodexetimideS Dupont
CEA, SHFJ, Orsay, France
J Nucl Med 40:935-41. 1999..Dexetimide is a specific mAChR antagonist that has been labeled recently with 76Br. This first study in humans focused on regional distribution and binding kinetics of [76Br]4-bromodexetimide (BDEX) in patients with MTLE...
- Lateralization of speech and auditory temporal processingP Belin
Service Hospitalier Frederic Joliot, Departement de Recherche Medicale, Orsay, France
J Cogn Neurosci 10:536-40. 1998..Such functional asymmetry in temporal processing is likely to contribute to language lateralization from the lowest levels of cortical processing...
- Three-dimensional reconstruction of the human central sulcus reveals a morphological correlate of the hand areaF A Sastre-Janer
CEA, Service Hospitalier Frederic Joliot, DSV DRM, Orsay, France
Cereb Cortex 8:641-7. 1998..These data suggest that the 3D anatomy of the cerebral cortex may facilitate sulcal recognition, and sulcal subdivision into smaller morphological elements, bearing remarkable relationships with functional cortical maps...
- Superior temporal sulcus anatomical abnormalities in childhood autism: a voxel-based morphometry MRI studyN Boddaert
ERM 0205 INSERM CEA, Service Hospitalier Frederic Joliot, CEA, 91406, Orsay, France
Neuroimage 23:364-9. 2004..Therefore, the convergent anatomical and functional temporal abnormalities observed in autism may be important in the understanding of brain behavior relationships in this severe developmental disorder...
- Hearing loss severity: impaired processing of formant transition durationA Coez
CEA INSERM U 1000 Neuroimaging and Psychiatry, Service Hospitalier Frederic Joliot, IFR49, 4 Place du General Leclerc, 91401 Orsay, France
Neuropsychologia 48:3057-61. 2010..These findings help to understand the limit of deafness rehabilitation in the time domain and should be taken into account in future devices development...
- Primary somatosensory cortex activation is not altered in patients with ventroposterior thalamic lesions: a PET studyP Remy
CEA, Service Hospitalier Frederic Joliot, Orsay, France
Stroke 30:2651-8. 1999..We know remarkably little about the mechanisms underlying cortical activation. Such mechanisms might be better understood by studying the effect of well-localized lesions on the cortical activations in simple paradigms...
- Cortical control of optokinetic nystagmus in humans: a positron emission tomography studyG Galati
SHFJ, Service Hospitalier Frederic Joliot, DSV DRM, Orsay, France
Exp Brain Res 126:149-59. 1999..Results are also discussed in terms of the specific kinds of OKN-related information processing subserved by each area in this network...
- Brain metabolism after recurrent insulin induced hypoglycaemic episodes: a PET studyH Chabriat
Service Hospitalier Frederic Joliot, DRIPP, CEA, Orsay, France
J Neurol Neurosurg Psychiatry 57:1360-5. 1994..This may be explained by the limited duration of hypoglycaemic coma induced by conventional insulin treatment...
- [Bitemporal lobe dysfonction in infantile autism: positron emission tomography study]N Boddaert
Service Hospitalier Frederic Joliot, ER M INSERM 0205, DSV, DRM, CEA, Orsay, 4, place du Général Leclerc 91406, Orsay, France
J Radiol 83:1829-33. 2002..The purpose of the present study was to research localized brain dysfunction in autistic children using functional brain imaging...
- Comparison of clinical data sets acquired on different tomographs using 6-18F-L-dopaM J Ribeiro
CEA, Service Hospitalier Frederic Joliot, DSV DRM, Orsay, France
Eur J Nucl Med 27:707-12. 2000..This can be accomplished using adequate modifications of the reconstruction parameters. Such modifications can be used to help in the longitudinal monitoring of parkinsonian patients using different tomographs...
- Is amygdalohippocampectomy really selective in medial temporal lobe epilepsy? A study using positron emission tomography with (18)fluorodeoxyglucoseS Dupont
Service Hospitalier Frederic Joliot, CEA, 4 Place du General Leclerc, 91406 Orsay, France
Epilepsia 42:731-40. 2001..However, the benefit of SAH in terms of functional outcome is debated. In this study, we aimed to assess the metabolic consequences of SAH...
- Temporal pole hypometabolism may be linked to a reduction of grey matter in temporal lobe epilepsySophie Dupont
Epilepsy Unit, Salpetriere Hospital, Paris, France
Neuroreport 13:2537-41. 2002..These findings suggest that a reduction of temporal pole neocortical grey matter might contribute to temporal pole hypometabolism in temporal lobe epilepsy...
- [An anatomofunctional brain database]Bénédicte Batrancourt
INSERM E 007, Centre de Neuropsychologie, Hopital de la Salpetriere, 47, Bd de l Hopital, 75651 Paris, France
C R Biol 325:439-55. 2002..A direct application would be the improvement of cognitive and/or behavioural rehabilitation of patients with brain damage...
- Functions of the left superior frontal gyrus in humans: a lesion studyFoucaud du Boisgueheneuc
Federation de Neurologie, Paris, France
Brain 129:3315-28. 2006..From a clinical perspective, this study provides new information on the impact of left SFG lesions on cognition that will be of use to neurologists and neurosurgeons...
- 18F-FDG PET in neurodegenerative Langerhans cell histiocytosis : results and potential interest for an early diagnosis of the diseaseMaria Joao Ribeiro
Service Hospitalier Frederic Joliot, DRM DSV, CEA 4, place du General Leclerc, 91406 Orsay, France
J Neurol 255:575-80. 2008..MRI is the gold standard to investigate CNS lesions of ND-LCH but little is known about functional changes observed in this disease...
- Cochlear implant benefits in deafness rehabilitation: PET study of temporal voice activationsArnaud Coez
CEA INSERM U797 Research Unit Neuroimaging and Psychiatry, Service Hospitalier Frederic Joliot, IFR49, Orsay, France
J Nucl Med 49:60-7. 2008..To test this hypothesis, we studied the activation of human temporal voice areas (TVA) using a well-standardized PET paradigm adapted from previous functional MRI (fMRI) studies...
- A novel approach to clinical-radiological correlations: Anatomo-Clinical Overlapping Maps (AnaCOM): method and validationSerge Kinkingnehun
INSERM U610, Paris, France
Neuroimage 37:1237-49. 2007..The method complements the functional imaging techniques, as it tells which regions are necessary for a given function and it explores cortical regions as well as the white matter...
- Leukoaraiosis is a risk factor for symptomatic intracerebral hemorrhage after thrombolysis for acute strokeTobias Neumann-Haefelin
Klinik fur Neurologie, ZNN, Klinikum der Goethe Universität, Schleusenweg 2 16, 60528 Frankfurt, Germany
Stroke 37:2463-6. 2006..The aim of the study was to evaluate whether leukoaraiosis (LA) is a risk factor for symptomatic intracerebral hemorrhage (sICH) in patients treated with thrombolysis for acute stroke...
- Autism, the superior temporal sulcus and social perceptionMonica Zilbovicius
URM 0205 Brain Imaging in Psychiatry, INSERM CEA, Service Hospitalier Frederic Joliot, CEA, 4 Place du General Leclerc, Orsay 91406, France
Trends Neurosci 29:359-66. 2006..This review is part of the INMED/TINS special issue "Nature and nurture in brain development and neurological disorders", based on presentations at the annual INMED/TINS symposium (http://inmednet.com/)...
- [Insulin in the treatment of ischemic stroke]Yves Samson
Urgences Cerebrovasculaires, Groupe Hospitalier Pitié Salpêtrière et Université Pierre et Marie Curie Paris VI, Paris
Presse Med 35:696-8. 2006..Preliminary data, which suggest that the speed and quality of glycemic control may be decisive in the efficacy of treatment, merit testing in a randomized trial...
- Autism severity and temporal lobe functional abnormalitiesIsabelle Gendry Meresse
ERM 0205 Institut National de la Sante et de la Recherche Médicale CEA, Service Hospitalier F Joliot, DSV, DRM, CEA, Orsay, France
Ann Neurol 58:466-9. 2005..The more severe the autistic syndrome, the more rCBF is low in this region, suggesting that left superior temporal hypoperfusion is related to autistic behavior severity...
- Autism: functional brain mapping of exceptional calendar capacityNathalie Boddaert
Service Hospitalier Frederic Joliot, DRM, DSV, CEA, 4 Place du General Leclerc 91406, Orsay, France
Br J Psychiatry 187:83-6. 2005..Autistic savants' are individuals with autism who have extraordinary skills. Brain mechanisms underlying such capacities are still unknown...
- Insular cortex involvement in mesiotemporal lobe epilepsy: a positron emission tomography studyViviane Bouilleret
Service Hospitalier Frederic Joliot, CEA, Orsay, France
Ann Neurol 51:202-8. 2002..Hypometabolism located in the insula did not influence postoperative outcome after anterior lobectomy...
- Abnormal cortical voice processing in autismHélène Gervais
ERM 0205, INSERM CEA, DRM, DSV, Service Hospitalier Frederic Joliot, 4, place du General Leclerc, 91406, Orsay, France
Nat Neurosci 7:801-2. 2004..These findings suggest abnormal cortical processing of socially relevant auditory information in autism...
- The role of dopamine in cognition: evidence from functional imaging studiesPhilippe Remy
URA CEA CNRS 2210, Service Hospitalier Frederic Joliot, Orsay, France
Curr Opin Neurol 16:S37-41. 2003..This paper reviews recent evidence provided by studies in healthy individuals and patients with Parkinson's disease or schizophrenia supporting the role of dopamine in normal and pathological cognitive processes...
- Perception of complex sounds: abnormal pattern of cortical activation in autismNathalie Boddaert
ERM 0205, Division of Life Sciences, Department of Medical Research, INSERM CEA Service Hospitalier Frédéric Joliot, 4 Place du General Leclerc, 91406 Orsay, France
Am J Psychiatry 160:2057-60. 2003..In normal adults, these regions are activated by listening to speech-like sounds. To investigate auditory cortical processing in autism, the authors performed a positron emission tomography activation study...
- Perception of complex sounds in autism: abnormal auditory cortical processing in childrenNathalie Boddaert
Commissariat a l Energie Atomique, Service Hospitalier Frederic Joliot, 4 Place du General Leclerc, 91406 Orsay, France
Am J Psychiatry 161:2117-20. 2004..Here, they investigated whether this abnormal cortical processing was also present in children with primary autism...