- [Auditory perception and language: functional imaging of speech sensitive auditory cortex]Y Samson
CEA, DRM, Service Hospitalier Frederic Joliot, Orsay, France
Rev Neurol (Paris) 157:837-46. 2001....
- [Thrombolytic treatment of cerebral infarction]Yves Samson
Rev Prat 52:1977-9. 2002
- Temporal lobe dysfunction in childhood autism: a PET study. Positron emission tomographyM Zilbovicius
Service Hospitalier Frederic Joliot, Direction des Sciences du Vivant, Département de Recherche, Commisariat à l Energie Atomique, Tours, France
Am J Psychiatry 157:1988-93. 2000..The authors reasoned that early methods may have been insensitive to such dysfunction, which may now be detectable with improved technology...
- Accurate prediction of postoperative outcome in mesial temporal lobe epilepsy: a study using positron emission tomography with 18fluorodeoxyglucoseS Dupont
Service Hospitalier Frederic Joliot, Commissariat a l Energie Atomique, 91401 Orsay Cedex, France
Arch Neurol 57:1331-6. 2000..Recent studies suggest that positron emission tomography may be a reliable predictive indicator of clinical outcome following surgical treatment for epilepsy...
- In vivo imaging of muscarinic cholinergic receptors in temporal lobe epilepsy with a new PET tracer: [76Br]4-bromodexetimideS Dupont
CEA, SHFJ, Orsay, France
J Nucl Med 40:935-41. 1999..Dexetimide is a specific mAChR antagonist that has been labeled recently with 76Br. This first study in humans focused on regional distribution and binding kinetics of [76Br]4-bromodexetimide (BDEX) in patients with MTLE...
- Lateralization of speech and auditory temporal processingP Belin
Service Hospitalier Frederic Joliot, Departement de Recherche Medicale, Orsay, France
J Cogn Neurosci 10:536-40. 1998..Such functional asymmetry in temporal processing is likely to contribute to language lateralization from the lowest levels of cortical processing...
- Three-dimensional reconstruction of the human central sulcus reveals a morphological correlate of the hand areaF A Sastre-Janer
CEA, Service Hospitalier Frederic Joliot, DSV DRM, Orsay, France
Cereb Cortex 8:641-7. 1998..These data suggest that the 3D anatomy of the cerebral cortex may facilitate sulcal recognition, and sulcal subdivision into smaller morphological elements, bearing remarkable relationships with functional cortical maps...
- Hearing loss severity: impaired processing of formant transition durationA Coez
CEA INSERM U 1000 Neuroimaging and Psychiatry, Service Hospitalier Frederic Joliot, IFR49, 4 Place du General Leclerc, 91401 Orsay, France
Neuropsychologia 48:3057-61. 2010..These findings help to understand the limit of deafness rehabilitation in the time domain and should be taken into account in future devices development...
- Superior temporal sulcus anatomical abnormalities in childhood autism: a voxel-based morphometry MRI studyN Boddaert
ERM 0205 INSERM CEA, Service Hospitalier Frederic Joliot, CEA, 91406, Orsay, France
Neuroimage 23:364-9. 2004..Therefore, the convergent anatomical and functional temporal abnormalities observed in autism may be important in the understanding of brain behavior relationships in this severe developmental disorder...
- Primary somatosensory cortex activation is not altered in patients with ventroposterior thalamic lesions: a PET studyP Remy
CEA, Service Hospitalier Frederic Joliot, Orsay, France
Stroke 30:2651-8. 1999..We know remarkably little about the mechanisms underlying cortical activation. Such mechanisms might be better understood by studying the effect of well-localized lesions on the cortical activations in simple paradigms...
- Cortical control of optokinetic nystagmus in humans: a positron emission tomography studyG Galati
SHFJ, Service Hospitalier Frederic Joliot, DSV DRM, Orsay, France
Exp Brain Res 126:149-59. 1999..Results are also discussed in terms of the specific kinds of OKN-related information processing subserved by each area in this network...
- Brain metabolism after recurrent insulin induced hypoglycaemic episodes: a PET studyH Chabriat
Service Hospitalier Frederic Joliot, DRIPP, CEA, Orsay, France
J Neurol Neurosurg Psychiatry 57:1360-5. 1994..This may be explained by the limited duration of hypoglycaemic coma induced by conventional insulin treatment...
- [Bitemporal lobe dysfonction in infantile autism: positron emission tomography study]N Boddaert
, ER-M INSERM 0205, DSV, DRM, CEA, Orsay, 4, , Orsay, France
J Radiol 83:1829-33. 2002..Such localized abnormalities were not detected with the low resolution PET camera,. This study suggests that high resolution PET camera combined with statistical parametric mapping is useful to understand developmental disorders...
- Comparison of clinical data sets acquired on different tomographs using 6-18F-L-dopaM J Ribeiro
CEA, Service Hospitalier Frederic Joliot, DSV DRM, Orsay, France
Eur J Nucl Med 27:707-12. 2000..This can be accomplished using adequate modifications of the reconstruction parameters. Such modifications can be used to help in the longitudinal monitoring of parkinsonian patients using different tomographs...
- Is amygdalohippocampectomy really selective in medial temporal lobe epilepsy? A study using positron emission tomography with (18)fluorodeoxyglucoseS Dupont
Service Hospitalier Frederic Joliot, CEA, 4 Place du General Leclerc, 91406 Orsay, France
Epilepsia 42:731-40. 2001..However, the benefit of SAH in terms of functional outcome is debated. In this study, we aimed to assess the metabolic consequences of SAH...
- Functions of the left superior frontal gyrus in humans: a lesion studyFoucaud du Boisgueheneuc
Federation de Neurologie, Paris, France
Brain 129:3315-28. 2006..From a clinical perspective, this study provides new information on the impact of left SFG lesions on cognition that will be of use to neurologists and neurosurgeons...
- Temporal pole hypometabolism may be linked to a reduction of grey matter in temporal lobe epilepsySophie Dupont
Epilepsy Unit, Salpetriere Hospital, Paris, France
Neuroreport 13:2537-41. 2002..These findings suggest that a reduction of temporal pole neocortical grey matter might contribute to temporal pole hypometabolism in temporal lobe epilepsy...
- [An anatomofunctional brain database]Bénédicte Batrancourt
INSERM E 007, Centre de Neuropsychologie, Hopital de la Salpetriere, 47, Bd de l Hopital, 75651 Paris, France
C R Biol 325:439-55. 2002..A direct application would be the improvement of cognitive and/or behavioural rehabilitation of patients with brain damage...
- The role of dopamine in cognition: evidence from functional imaging studiesPhilippe Remy
URA CEA CNRS 2210, Service Hospitalier Frederic Joliot, Orsay, France
Curr Opin Neurol 16:S37-41. 2003..This paper reviews recent evidence provided by studies in healthy individuals and patients with Parkinson's disease or schizophrenia supporting the role of dopamine in normal and pathological cognitive processes...
- 18F-FDG PET in neurodegenerative Langerhans cell histiocytosis : results and potential interest for an early diagnosis of the diseaseMaria Joao Ribeiro
Service Hospitalier Frederic Joliot, DRM DSV, CEA 4, place du General Leclerc, 91406 Orsay, France
J Neurol 255:575-80. 2008..MRI is the gold standard to investigate CNS lesions of ND-LCH but little is known about functional changes observed in this disease...
- Cochlear implant benefits in deafness rehabilitation: PET study of temporal voice activationsArnaud Coez
CEA INSERM U797 Research Unit Neuroimaging and Psychiatry, Service Hospitalier Frederic Joliot, IFR49, Orsay, France
J Nucl Med 49:60-7. 2008..To test this hypothesis, we studied the activation of human temporal voice areas (TVA) using a well-standardized PET paradigm adapted from previous functional MRI (fMRI) studies...
- A novel approach to clinical-radiological correlations: Anatomo-Clinical Overlapping Maps (AnaCOM): method and validationSerge Kinkingnehun
INSERM U610, Paris, France
Neuroimage 37:1237-49. 2007..The method complements the functional imaging techniques, as it tells which regions are necessary for a given function and it explores cortical regions as well as the white matter...
- Leukoaraiosis is a risk factor for symptomatic intracerebral hemorrhage after thrombolysis for acute strokeTobias Neumann-Haefelin
Klinik fur Neurologie, ZNN, Klinikum der Goethe Universität, Schleusenweg 2 16, 60528 Frankfurt, Germany
Stroke 37:2463-6. 2006..The aim of the study was to evaluate whether leukoaraiosis (LA) is a risk factor for symptomatic intracerebral hemorrhage (sICH) in patients treated with thrombolysis for acute stroke...
- Autism, the superior temporal sulcus and social perceptionMonica Zilbovicius
URM 0205 Brain Imaging in Psychiatry, INSERM CEA, Service Hospitalier Frederic Joliot, CEA, 4 Place du General Leclerc, Orsay 91406, France
Trends Neurosci 29:359-66. 2006..This review is part of the INMED/TINS special issue "Nature and nurture in brain development and neurological disorders", based on presentations at the annual INMED/TINS symposium (http://inmednet.com/)...
- [Insulin in the treatment of ischemic stroke]Yves Samson
Urgences Cerebrovasculaires, Groupe Hospitalier Pitié Salpêtrière et Université Pierre et Marie Curie Paris VI, Paris
Presse Med 35:696-8. 2006..Preliminary data, which suggest that the speed and quality of glycemic control may be decisive in the efficacy of treatment, merit testing in a randomized trial...
- Insular cortex involvement in mesiotemporal lobe epilepsy: a positron emission tomography studyViviane Bouilleret
, CEA, Orsay, France
Ann Neurol 51:202-8. 2002..Hypometabolism located in the insula did not influence postoperative outcome after anterior lobectomy...
- Autism: functional brain mapping of exceptional calendar capacityNathalie Boddaert
, DRM, DSV, CEA, 4 Place du General Leclerc 91406, Orsay, France
Br J Psychiatry 187:83-6. 2005..These results suggest that the prodigious capacities may be sustained by memory processing...
- Perception of complex sounds in autism: abnormal auditory cortical processing in childrenNathalie Boddaert
Commissariat a l'Energie Atomique, , , 91406 Orsay, France
Am J Psychiatry 161:2117-20. 2004..The abnormal cortical auditory processing observed in both children and adults with autism could be involved in inadequate behavioral responses to sounds and in language impairments characteristic of autism...
- Perception of complex sounds: abnormal pattern of cortical activation in autismNathalie Boddaert
ERM 0205, Division of Life Sciences, Department of Medical Research, , , 91406 Orsay, France
Am J Psychiatry 160:2057-60. 2003..CONCLUSIONS: These findings suggest that abnormal auditory cortical processing is implicated in the language impairments and the inadequate response to sounds typically seen in autism...
- Abnormal cortical voice processing in autismHélène Gervais
ERM 0205, INSERM CEA, DRM, DSV, Service Hospitalier Frederic Joliot, 4, place du General Leclerc, 91406, Orsay, France
Nat Neurosci 7:801-2. 2004..These findings suggest abnormal cortical processing of socially relevant auditory information in autism...
- Autism severity and temporal lobe functional abnormalitiesIsabelle Gendry Meresse
, Service Hospitalier F Joliot, DSV, DRM, CEA, Orsay, France
Ann Neurol 58:466-9. 2005..The more severe the autistic syndrome, the more rCBF is low in this region, suggesting that left superior temporal hypoperfusion is related to autistic behavior severity...