Research Topics
Species | Audrey SabbaghSummaryCountry: France Publications
| Collaborators
|
Detail Information
Publications
Inferring haplotypes at the NAT2 locus: the computational approachAudrey Sabbagh
Unité de Recherche en Génétique Epidémiologique et Structure des Populations Humaines, INSERM U535, Villejuif, France
BMC Genet 6:30. 2005..The objective of this study was to assess the performance of the computational approach in NAT2 haplotype reconstruction from phase-unknown genotype data, for population samples of various ethnic origin...
Data-mining methods as useful tools for predicting individual drug response: application to CYP2D6 dataAudrey Sabbagh
Unité de Recherche en Génétique Epidémiologique et Structure des Populations Humaines, INSERM U535, Villejuif, France
Hum Hered 62:119-34. 2006..In this study, we investigated the ability of several pattern recognition methods to identify the most informative markers in the CYP2D6 gene for the prediction of CYP2D6 metabolizer status...
Selecting predictive markers for pharmacogenetic traits: tagging vs. data-mining approachesAudrey Sabbagh
INSERM, UMR S0535, Villejuif, France
Hum Hered 66:10-8. 2008..We undertook a study to provide further insights into the usefulness of the tagging approach for selecting phenotype-associated markers relevant to drug response...
Worldwide distribution of NAT2 diversity: implications for NAT2 evolutionary historyAudrey Sabbagh
INSERM U535, BP 1000, 94817 Villejuif Cedex, France
BMC Genet 9:21. 2008....
SNP selection at the NAT2 locus for an accurate prediction of the acetylation phenotypeAudrey Sabbagh
Unité de Recherche en Génétique Epidémiologique et Structure des Populations Humaines, INSERM U535, Villejuif, France
Genet Med 8:76-85. 2006....
Association between ABCB1 C3435T polymorphism and increased risk of cannabis dependenceAmine Benyamina
INSERM, U669, Paris, France
Prog Neuropsychopharmacol Biol Psychiatry 33:1270-4. 2009..ABCB1 polymorphisms may alter Delta9THC distribution, its psychoactive effects and individual vulnerability to dependence. These results pave the way to a new pharmacogenetic hypothesis in cannabis dependence...
Parental genotypes in the risk of a complex diseaseDamian Labuda
Centre de Recherche, Hopital Sainte Justine, Universite de Montreal, Quebec, H3T 1C5 Canada
Am J Hum Genet 71:193-7. 2002..Consequently, in addition to TDT, other complementary strategies will need to be simultaneously applied to dissect genetic predisposition to complex disorders...
Decreasing the effects of horizontal gene transfer on bacterial phylogeny: the Escherichia coli case studyPatricia Escobar-Paramo
INSERM E0339, IFR 02, Faculte de Medecine Xavier Bichat, 16 rue Henri Huchard, Paris 75018, France
Mol Phylogenet Evol 30:243-50. 2004..Furthermore, this work allowed a significant improvement of the accuracy of the phylogeny within E. coli...
