Christian Roux

Summary

Country: France

Publications

  1. ncbi request reprint Vertebral fracture risk reduction with strontium ranelate in women with postmenopausal osteoporosis is independent of baseline risk factors
    Christian Roux
    Universite Paris Descartes, Faculte de Medecine, Assistance Publique Hopitaux de Paris, Hopital Cochin, Service de Rhumatologie, Paris, France
    J Bone Miner Res 21:536-42. 2006
  2. doi request reprint Burden of non-hip, non-vertebral fractures on quality of life in postmenopausal women: the Global Longitudinal study of Osteoporosis in Women (GLOW)
    C Roux
    Department of Rheumatology, Cochin Hospital, Paris Descartes University, 27 rue du Faubourg St Jacques, 75659, Paris Cedex 14, France
    Osteoporos Int 23:2863-71. 2012
  3. pmc Cross-cultural validation and analysis of responsiveness of the QUALIOST: QUAlity of Life questionnaire In OSTeoporosis
    Christine de la Loge
    Mapi Values, 27 rue de la Villette, 69003, Lyon, France
    Health Qual Life Outcomes 3:69. 2005
  4. pmc Body weight, body composition, and bone turnover changes in patients with spondyloarthropathy receiving anti-tumour necrosis factor {alpha} treatment
    K Briot
    Hopital Cochin, Departement de Rhumatologie, 27 rue du Faubourg St Jacques, 75014 Paris, France
    Ann Rheum Dis 64:1137-40. 2005
  5. ncbi request reprint Long-term safety of fluticasone propionate and nedocromil sodium on bone in children with asthma
    Christian Roux
    Hopital Cochin, Assistance Publique Hopitaux de Paris, Universite Rene Descartes, Paris, France
    Pediatrics 111:e706-13. 2003
  6. ncbi request reprint [Steroid induced osteoporosis: prevention and treatment]
    C Roux
    Institut de Rhumatologie, Hopital Cochin, Centre d Evaluation des Maladies Osseuses, 27, rue du Faubourg Saint Jacques, 75014, Paris, France
    Rev Med Interne 24:384-8. 2003
  7. ncbi request reprint Recommendations for monitoring antiresorptive therapies in postmenopausal osteoporosis
    Christian Roux
    Groupe de Recherche et d Information sur les Ostéoporoses Task Force for Research and Information on Osteoporosis, Hopital Cochin, 27, rue du Faubourg St Jacques, 75014, Paris, France
    Joint Bone Spine 72:26-31. 2005
  8. ncbi request reprint [Non-invasive method for measuring bone mineral density]
    Christian Roux
    Centre d Evaluation des Maladies Osseuses, Institut de Rhumatologie, Hopital Cochin, 27, rue du Faubourg Saint Jacques, 75014 Paris, France
    Med Sci (Paris) 19:231-8. 2003
  9. pmc Assessment of non-vertebral fracture risk in postmenopausal women
    Christian Roux
    Universite Paris Descartes, Faculte de Medecine, Assistance Publique Hopitaux de Paris, Hopital Cochin, Service de Rhumatologie, Paris 75014, France
    Ann Rheum Dis 66:931-5. 2007
  10. doi request reprint Influence of vertebral fracture assessment by dual-energy X-ray absorptiometry on decision-making in osteoporosis: a structured vignette survey
    Christian Roux
    Rheumatology Department, Paris Descartes University, Paris, France
    Rheumatology (Oxford) 50:2264-9. 2011

Detail Information

Publications120 found, 100 shown here

  1. ncbi request reprint Vertebral fracture risk reduction with strontium ranelate in women with postmenopausal osteoporosis is independent of baseline risk factors
    Christian Roux
    Universite Paris Descartes, Faculte de Medecine, Assistance Publique Hopitaux de Paris, Hopital Cochin, Service de Rhumatologie, Paris, France
    J Bone Miner Res 21:536-42. 2006
    ..Strontium ranelate (2 g/day) was studied in 5082 postmenopausal women. A reduction in incident vertebral fracture risk by 40% was shown after 3 years. This effect was independent of age, initial BMD, and prevalent vertebral fractures...
  2. doi request reprint Burden of non-hip, non-vertebral fractures on quality of life in postmenopausal women: the Global Longitudinal study of Osteoporosis in Women (GLOW)
    C Roux
    Department of Rheumatology, Cochin Hospital, Paris Descartes University, 27 rue du Faubourg St Jacques, 75659, Paris Cedex 14, France
    Osteoporos Int 23:2863-71. 2012
    ..Spine fractures had the greatest detrimental effect on EQ-5D, followed by major NHNV and hip fractures. Decreases in physical function and health status were greatest for spine or hip fractures...
  3. pmc Cross-cultural validation and analysis of responsiveness of the QUALIOST: QUAlity of Life questionnaire In OSTeoporosis
    Christine de la Loge
    Mapi Values, 27 rue de la Villette, 69003, Lyon, France
    Health Qual Life Outcomes 3:69. 2005
    ..The objective of this paper is to provide additional information on the instrument's responsiveness using clinical trial data, along with the reliability and validity of translated versions...
  4. pmc Body weight, body composition, and bone turnover changes in patients with spondyloarthropathy receiving anti-tumour necrosis factor {alpha} treatment
    K Briot
    Hopital Cochin, Departement de Rhumatologie, 27 rue du Faubourg St Jacques, 75014 Paris, France
    Ann Rheum Dis 64:1137-40. 2005
    ..To determine the changes in body weight, body composition, and bone turnover in patients with spondyloarthropathy (SpA) treated with anti-tumour necrosis factor alpha (TNFalpha)...
  5. ncbi request reprint Long-term safety of fluticasone propionate and nedocromil sodium on bone in children with asthma
    Christian Roux
    Hopital Cochin, Assistance Publique Hopitaux de Paris, Universite Rene Descartes, Paris, France
    Pediatrics 111:e706-13. 2003
    ..Inhaled corticosteroids are recommended as first-line therapy for pediatric asthma. However, few controlled long-term studies have investigated their effect on bone mineral density (BMD) and growth...
  6. ncbi request reprint [Steroid induced osteoporosis: prevention and treatment]
    C Roux
    Institut de Rhumatologie, Hopital Cochin, Centre d Evaluation des Maladies Osseuses, 27, rue du Faubourg Saint Jacques, 75014, Paris, France
    Rev Med Interne 24:384-8. 2003
    ..New data from biological, epidemiological and therapeutic studies provide basis for optimal management of this bone disease...
  7. ncbi request reprint Recommendations for monitoring antiresorptive therapies in postmenopausal osteoporosis
    Christian Roux
    Groupe de Recherche et d Information sur les Ostéoporoses Task Force for Research and Information on Osteoporosis, Hopital Cochin, 27, rue du Faubourg St Jacques, 75014, Paris, France
    Joint Bone Spine 72:26-31. 2005
    ..Biochemical markers for bone turnover can be monitored after only 3-6 months provided steps are taken to control for intraindividual variability. They are useful when patient compliance is poor or the treatment response inadequate...
  8. ncbi request reprint [Non-invasive method for measuring bone mineral density]
    Christian Roux
    Centre d Evaluation des Maladies Osseuses, Institut de Rhumatologie, Hopital Cochin, 27, rue du Faubourg Saint Jacques, 75014 Paris, France
    Med Sci (Paris) 19:231-8. 2003
    ..Thus, therapeutic decision is based on both BMD and clinical risk factors that contribute to fracture risk...
  9. pmc Assessment of non-vertebral fracture risk in postmenopausal women
    Christian Roux
    Universite Paris Descartes, Faculte de Medecine, Assistance Publique Hopitaux de Paris, Hopital Cochin, Service de Rhumatologie, Paris 75014, France
    Ann Rheum Dis 66:931-5. 2007
    ..Non-vertebral (NV) fractures are responsible for a great amount of morbidity, mortality and cost attributable to osteoporosis...
  10. doi request reprint Influence of vertebral fracture assessment by dual-energy X-ray absorptiometry on decision-making in osteoporosis: a structured vignette survey
    Christian Roux
    Rheumatology Department, Paris Descartes University, Paris, France
    Rheumatology (Oxford) 50:2264-9. 2011
    ..This study was designed to assess the impact of VFA results on decision-marking in osteoporosis, using a clinical vignette-based approach...
  11. ncbi request reprint [Diagnosis of osteoporosis]
    Christian Roux
    Service de Rhumatologie, Hopital Cochin, 75014 Paris
    Rev Prat 54:2107-19. 2004
    ..Osteoporosis may be related to malignant and metabolic diseases, which must be checked before any treatment...
  12. pmc Management of osteoporosis: a physiological answer for a living tissue. Introduction
    C Roux
    Rheumatology Department, Paris Descartes University, Cochin Hospital, Paris, France
    Rheumatology (Oxford) 47:iv1. 2008
  13. pmc Strontium ranelate: short- and long-term benefits for post-menopausal women with osteoporosis
    C Roux
    Rheumatology Department, Paris Descartes University, Cochin Hospital, Paris, France
    Rheumatology (Oxford) 47:iv20-22. 2008
    ..During these clinical trials, safety was good. Its large spectrum of efficacy allows the use of strontium ranelate in the different subgroups of patients with post-menopausal osteoporosis...
  14. ncbi request reprint Efficacy of risedronate on clinical vertebral fractures within six months
    Christian Roux
    Cochin Hospital, Rene Descartes University, Paris, France
    Curr Med Res Opin 20:433-9. 2004
    ..Risedronate has been shown to reduce the incidence of radiographically-defined vertebral fractures by approximately two-thirds within 1 year...
  15. ncbi request reprint [Paget's disease, workup and monitoring]
    Christian Roux
    Institut de Rhumatologie, Hôpital Cochin Université René Descartes, 27, rue du Faubourg St Jacques, Paris
    Presse Med 34:608-11. 2005
    ..Total alkaline phosphatase is the best marker and measurement of collagen breakdown products is useful in difficult cases. The goal of treatment is the normalization of these biological markers, to prevent complications of the disease...
  16. ncbi request reprint Serum leptin as a determinant of bone resorption in healthy postmenopausal women
    Christian Roux
    Centre d Evaluation des Maladies Osseuses, Departement de Rhumatologie, Hopital Cochin AP HP, Universite Rene Descartes, Paris, France
    Bone 33:847-52. 2003
    ..In conclusion, leptin may play a role as a determinant of bone resorption in healthy, untreated postmenopausal women, but the effect of estradiol or tibolone on bone are not mediated by leptin...
  17. ncbi request reprint [Postmenopausal osteoporosis: current treatment]
    C Roux
    Service de Rhumatologie, Hopital Cochin, 27, rue du Faubourg Saint Jacques, 75014 Paris, France
    Rev Med Interne 25:S568-72. 2004
    ..Based on anti fracture efficacy of treatments, it is relevant to assess post menopausal women for the risk of osteoporotic fractures, based on clinical risk factors and bone mineral density measurements...
  18. pmc A clinical tool to determine the necessity of spine radiography in postmenopausal women with osteoporosis presenting with back pain
    C Roux
    Universite Paris Descartes, Hopital Cochin, Paris, France
    Ann Rheum Dis 66:81-5. 2007
    ..In a population of postmenopausal women with osteoporosis and back pain, symptoms may be related to vertebral fractures or degenerative changes of the spine...
  19. ncbi request reprint Quantitative ultrasound in postmenopausal osteoporosis
    C Roux
    Centre d Evaluation des Maladies Osseuses, Departement de Rhumatologie, Hopital Cochin, Universite Rene Descartes, Paris, France
    Curr Opin Rheumatol 12:336-45. 2000
    ..Monitoring of skeletal changes and treatment effects by ultrasound cannot be recommended...
  20. ncbi request reprint [Osteoporosis and hormone replacement therapy]
    Christian Roux
    Service de Rhumatologie, Universite Rene Descartes, Hopital Cochin, 27, rue du Faubourg, St Jacques, 75014 Paris
    Presse Med 34:379-84. 2005
    ..The menopause is the occasion to assess individual risks, notably vascular and of fractures, taking into account the clinical risk factors and measurement of bone density...
  21. ncbi request reprint Calcitonin in glucocorticoid-induced osteoporosis
    C Roux
    Departement de Rhumatologie, Hopital Cochin, Universite Rene Descartes, Paris, France
    Front Horm Res 30:145-9. 2002
  22. ncbi request reprint Mild prevalent and incident vertebral fractures are risk factors for new fractures
    C Roux
    Cochin Hospital, Rheumatology Department, University of Paris, 27, rue du Faubourg St Jacques, 75014, Paris, France
    Osteoporos Int 18:1617-24. 2007
    ..This prospective four-year study indicates that post-menopausal osteoporotic women with mild prevalent and incident vertebral fractures have an increased risk of incident fractures...
  23. ncbi request reprint Randomized, double-masked, 2-year comparison of tibolone with 17beta-estradiol and norethindrone acetate in preventing postmenopausal bone loss
    C Roux
    Centre d Evaluation des Maladies Osseuses, Departement de Rhumatologie, Hopital Cochin, Universite Rene Descartes, Paris, France
    Osteoporos Int 13:241-8. 2002
    ..7% and 2.6%, respectively). Each treatment effectively prevented bone loss. Overall, tolerability of tibolone was better than with E2/NETA, because of less frequent vaginal bleeding and breast pain. This may promote long-term adherence...
  24. ncbi request reprint Prospective assessment of body weight, body composition, and bone density changes in patients with spondyloarthropathy receiving anti-tumor necrosis factor-alpha treatment
    Karine Briot
    Paris Descartes University, Medicine Faculty, Cochin Hospital, Paris, France
    J Rheumatol 35:855-61. 2008
    ..To determine the changes in body weight, body composition, and bone density in patients with spondyloarthropathy (SpA) receiving anti-tumor necrosis factor-alpha (TNF-alpha) treatment...
  25. ncbi request reprint How long should patients take medications for postmenopausal osteoporosis?
    Karine Briot
    Rheumatology Department, Paris Descartes University, School of Medecine, 75014 Paris, France
    Joint Bone Spine 74:24-31. 2007
    ..Thus, 4 years may be appropriate for anti-resorptive drug therapy. However, the optimal treatment duration should be determined on a case-by-case basis according to the results of regular fracture-risk evaluations...
  26. doi request reprint Bone oedema on MRI is highly associated with low bone mineral density in patients with early inflammatory back pain: results from the DESIR cohort
    Karine Briot
    Department of Rheumatology, Cochin Hospital, Paris Descartes University, Paris, France
    Ann Rheum Dis 72:1914-9. 2013
    ....
  27. ncbi request reprint Bone status in primary hyperparathyroidism assessed by regional bone mineral density from the whole body scan and QUS imaging at calcaneus
    Christine Chappard
    Service de Physiologie et Radio isotopes, Hopital Europeen Georges Pompidou, Paris, France
    Joint Bone Spine 73:86-94. 2006
    ..Indeed, the distal part of the limbs are the most affected areas in PHPT whatever the amount of cortical or trabecular bone...
  28. doi request reprint Male osteoporosis: diagnosis and fracture risk evaluation
    Karine Briot
    Service de Rhumatologie, Hopital Cochin, 27 rue du Faubourg St Jacques, 75014 Paris, France
    Joint Bone Spine 76:129-33. 2009
    ..The identification of men at high risk for fractures requires a combined evaluation of bone mineral density data, clinical risk factors, and risk factors for falls...
  29. doi request reprint Severe osteoporosis: diagnosis and follow-up. Lessons for clinical practice
    Christian Roux
    Service de Rhumatologie B, Universite Paris Descartes, Hopital Cochin, Paris, France
    Joint Bone Spine 77:S139-41. 2010
    ..This statement was validated by a panel of 70 French rheumatologists at the first national ODISSEE meeting held on November 13-14, 2009...
  30. doi request reprint [Vitamin D: skeletal and extra skeletal effects; recommendations for good practice]
    Karine Briot
    Service de Rhumatologie, Hopital Cochin, F 75679 Paris cedex 14, France
    Presse Med 38:43-54. 2009
    ..and the measurement of the serum 25OHD level is the only way to determine the vitamin D status. It is recommended to measure the serum 25OHD level in patients with osteoporosis or at risk of osteoporosis, and to correct the deficiency...
  31. ncbi request reprint Prevalence of risk factors for referring post-menopausal women for bone densitometry. The INSTANT study
    Christian Roux
    Rheumatology Department, Paris Descartes University, Cochin Hospital, Paris, France
    Joint Bone Spine 75:702-7. 2008
    ..Measurement of bone density by densitometry is an appropriate public health strategy for prevention of osteoporotic fractures in at-risk individuals, and physicians are encouraged to screen for these risk factors in post-menopausal women...
  32. ncbi request reprint Injection of intra-articular sodium hyaluronidate (Sinovial) into the carpometacarpal joint of the thumb (CMC1) in osteoarthritis. A prospective evaluation of efficacy
    Christian Roux
    University Hospital l Archet 1, Rheumatology Department, CHU Nice, France
    Joint Bone Spine 74:368-72. 2007
    ..To compare the efficacy on pain relief and function of one, two or three injections of intra-articular hyaluronic acid in symptomatic osteoarthritis (OA) of the carpometacarpal joint of the thumb (CMCJ)...
  33. doi request reprint Added value of trabecular bone score to bone mineral density for prediction of osteoporotic fractures in postmenopausal women: the OPUS study
    Karine Briot
    Paris Descartes University, Rheumatology Department, Cochin Hospital, Paris, France Electronic address
    Bone 57:232-6. 2013
    ..The objective of this study was to consider whether trabecular bone score (TBS) improves on areal bone mineral density (aBMD) measurement alone for the prediction of incident fractures in postmenopausal women...
  34. ncbi request reprint Oxytocin, a new determinant of bone mineral density in post-menopausal women: analysis of the OPUS cohort
    Veronique Breuil
    Department of Rheumatology V B, H B Y, L E Z, Nice University Hospital, Archet Hospital, Faculté de Médecine V B, L E Z, E Z A, University Nice Sophia Antipolis, Department of Hormonolgy P P F, H B Y, S F, Nice University Hospital, St Roch Hospital, and Department of Clinical Research E F, Nice University Hospital, Cimiez Hospital, Nice F 06003, France Department of Rheumatology C R, S K, INSERM, Unité 1153, Paris Descartes University, Cochin Hospital, F 75014 Paris, France Academic Unit of Bone Metabolism R E, F G, University of Sheffield, Sheffield S10 2JF, United Kingdom Centre National de la Recherche Scientifique H B Y, E Z A, Institut de Biologie Valrose Unité Mixte de Recherche 7277, and INSERM H B Y, E Z A, Utrecht
    J Clin Endocrinol Metab 99:E634-41. 2014
    ..This study assessed the relationship between OT and bone status in a large population of postmenopausal women...
  35. ncbi request reprint [Drug treatment of postmenopausal osteoporosis. What's New in 2006]
    Christian Roux
    Service de Rhumatologie, Hopital Cochin, Paris 75
    Presse Med 35:1529-39. 2006
  36. ncbi request reprint Increase in bone density in patients with spondyloarthritis during anti-tumor necrosis factor therapy: 6-year followup study
    Anne Durnez
    From Paris Descartes University, Rheumatology Department, Cochin Hospital, Paris, France Rheumatology Department, AZ Groeninge, Kortrijk, Belgium and the University of Amsterdam, Amsterdam, and Atrium Medical Center, Heerlen, The Netherlands
    J Rheumatol 40:1712-8. 2013
    ....
  37. doi request reprint Lumbar disc degeneration in osteoporotic men: prevalence and assessment of the relation with presence of vertebral fracture
    Isabelle Fabreguet
    Department of Rheumatology B, Cochin Hospital, Paris Descartes University, Paris, France
    J Rheumatol 40:1183-90. 2013
    ..An inverse relationship between spine OA and the presence of prevalent vertebral fractures has been shown in osteoporotic women. Our objective was to assess this relationship in osteoporotic men...
  38. ncbi request reprint Inactivation of the Na-Cl co-transporter (NCC) gene is associated with high BMD through both renal and bone mechanisms: analysis of patients with Gitelman syndrome and Ncc null mice
    Laurence Nicolet-Barousse
    Departement de Physiologie, Hôpital Européen George Pompidou, Institut National de la Santé et de la Recherche Médicale INSERM U 652, IFR 58, Universite Paris V, Paris, France
    J Bone Miner Res 20:799-808. 2005
    ....
  39. ncbi request reprint A double-blind placebo-controlled study of intravenous clodronate for prevention of steroid-induced bone loss in inflammatory bowel disease
    Vered Abitbol
    Assistance Publique Hopitaux de Paris, Gastroenterologie, Hopital Cochin, Paris, France
    Clin Gastroenterol Hepatol 5:1184-9. 2007
    ..Our aim was to assess the efficacy of intravenous clodronate in preventing steroid-induced bone loss...
  40. ncbi request reprint Which variables best predict change in rheumatoid arthritis therapy in daily clinical practice?
    Martin Soubrier
    Service de Rhumatologie, Hopital G Montpied, Clermont Ferrand, France
    J Rheumatol 33:1243-6. 2006
    ..To determine in clinical practice which clinical status variables for rheumatoid arthritis (RA) are most closely associated with a change in disease modifying antirheumatic drug (DMARD) therapy...
  41. doi request reprint Prospective assessment of thoracic kyphosis in postmenopausal women with osteoporosis
    Christian Roux
    Paris Descartes University, Cochin Hospital, Rheumatology Department, Paris, France
    J Bone Miner Res 25:362-8. 2010
    ..Thoracic kyphosis progression over three years is lower in a subgroup of strontium ranelate-treated patients compared with placebo-treated patients...
  42. doi request reprint Severe osteoporosis: does structural monitoring help?
    Ariane Leboime
    Universite Paris Descartes, Hopital Cochin, Service de Rhumatologie B, 27 rue du Faubourg Saint Jacques, Paris, France
    Joint Bone Spine 77:S113-6. 2010
    ..VFA used in conjunction with absorptiometry may be well suited to the monitoring of women with severe osteoporosis...
  43. doi request reprint Changes in bone mineral density over a 2-year period in HIV-1-infected men under combined antiretroviral therapy with osteopenia
    Lambert Assoumou
    aINSERM bUPMC Univ Paris 06, UMRS 943 cAP HP, Hopital Pitie Salpetriere, Service de Maladies Infectieuses et Tropicales dAP HP, Centre de Diagnostic et de Thérapeutique, Hotel Dieu, Paris eAP HP, Hopital Avicenne, Service de Maladies Infectieuses, Bobigny fAP HP, Hopital Pitie Salpetriere, Service de médecines internes gRheumatology Department, Cochin Hospital, Paris Descartes University hAP HP, Hopital Pitie Salpetriere, Service de Rhumatologie and UPMC Univ Paris 06, Paris, France
    AIDS 27:2425-30. 2013
    ..We aimed to evaluate the course of osteopenia over a 2-year period in HIV-1-infected men, and to identify risk factors for abnormal bone mineral density (BMD) decline...
  44. ncbi request reprint Diagnosis of vertebral fractures by vertebral fracture assessment
    Joel Damiano
    Service de Rhumatologie, Universite Paris Descartes, Faculte de Medecine, Assistance Publique Hopitaux de Paris, Hopital Cochin, Paris, France
    J Clin Densitom 9:66-71. 2006
    ..VFA is a reliable technique with low radiation, and is easily and rapidly applicable during bone density measurement by DXA, which could improve management of osteoporotic patients...
  45. doi request reprint Identification of rheumatoid arthritis patients with vertebral fractures using bone mineral density and trabecular bone score
    Sophie Breban
    Department of Rheumatology, Paris Descartes University, Cochin Hospital, Paris, France
    J Clin Densitom 15:260-6. 2012
    ..In this population, at low risk according to BMD, TBS could help to detect patients with VF...
  46. doi request reprint Hip cortical thickness assessment in postmenopausal women with osteoporosis and strontium ranelate effect on hip geometry
    Karine Briot
    Rheumatology Department, Cochin Hospital, Paris Descartes University, Paris, France
    J Clin Densitom 15:176-85. 2012
    ..Some HSA parameters have predictive value for hip fracture risk in postmenopausal osteoporotic women. Strontium ranelate improves some HSA parameters, through the BMD increase...
  47. doi request reprint Calcium intake and the risk of osteoporosis and fractures in French women
    Patrice Fardellone
    INSERM ERI 12, Service de Rhumatologie, Amiens University Hospital, CHU Nord, Place Victor Pauchet, 80054 Amiens cedex 01, France
    Joint Bone Spine 77:154-8. 2010
    ..To evaluate dietary calcium intake in postmenopausal women over 45 years of age and compare intake according to osteoporosis diagnosis and fracture history...
  48. ncbi request reprint Effects of etanercept on serum biochemical markers of cartilage metabolism in patients with spondyloarthropathy
    Karine Briot
    Faculte de Medecine, Universite Paris Descartes, UPRES EA 4058, Hopital Cochin, Paris, France
    J Rheumatol 35:310-4. 2008
    ..We describe the effects of etanercept on biochemical markers of type II collagen synthesis and degradation in patients with SpA followed for 2 years...
  49. ncbi request reprint Osteoporosis in inflammatory bowel disease: effect of calcium and vitamin D with or without fluoride
    V Abitbol
    Service de Gastroenterologie, Hopital Cochin, Paris, France, INSERM U444, UNIVERSITE DE PARIS, Paris, France
    Aliment Pharmacol Ther 16:919-27. 2002
    ..Previous data have indicated low bone formation as a mechanism of osteoporosis in inflammatory bowel disease. Fluoride can stimulate bone formation...
  50. pmc FRAX®: Prediction of Major Osteoporotic Fractures in Women from the General Population: The OPUS Study
    Karine Briot
    Paris Descartes University, Rheumatology Department, Cochin Hospital, Paris, France
    PLoS ONE 8:e83436. 2013
    ..The aim of this study was to analyse how well FRAX® predicts the risk of major osteoporotic and vertebral fractures over 6 years in postmenopausal women from general population...
  51. doi request reprint Real frequency of ordinary and atypical sub-trochanteric and diaphyseal fractures in France based on X-rays and medical file analysis
    Constance Beaudouin-Bazire
    Service de Rhumatologie B, Hopital Cochin, Universite Paris Descartes, Paris, France
    Joint Bone Spine 80:201-5. 2013
    ..Therefore, the aim of our study was to estimate the real frequency of typical and atypical sub-trochanteric or diaphyseal fractures, based on radiological and clinical data compared to registered data...
  52. doi request reprint 2012 update of French guidelines for the pharmacological treatment of postmenopausal osteoporosis
    Karine Briot
    Service de Rhumatologie, Hopital Cochin, Universite Paris Descartes, Paris, France
    Joint Bone Spine 79:304-13. 2012
    ....
  53. doi request reprint Increase in vertebral fracture risk in postmenopausal women using omeprazole
    Christian Roux
    Rheumatology Department, AP HP Cochin Hospital, Paris Descartes University, 27 rue Faubourg Saint Jacques, Paris 75014, France
    Calcif Tissue Int 84:13-9. 2009
    ..Further studies are required to determine the mechanism of the association between the underlying gastric disease, omeprazole use, and risk of osteoporotic fractures...
  54. ncbi request reprint Chondrocalcinosis secondary to hypomagnesemia in Gitelman's syndrome
    Hang Korng Ea
    Rheumatology Department, Rene Descartes University, France
    J Rheumatol 32:1840-2. 2005
    ..Additionally, the association between GS (NCCT inactivation) and high bone mineral density provides a new insight into the possible role of thiazides in osteoporosis management...
  55. ncbi request reprint New insights into the role of vitamin D and calcium in osteoporosis management: an expert roundtable discussion
    C Roux
    Cochin Hospital, Rheumatology Department, Paris Descartes University, Paris, France
    Curr Med Res Opin 24:1363-70. 2008
    ..Adequate vitamin D and calcium nutrition play a critical role in the maintenance of musculoskeletal health and are considered the first step in osteoporosis treatment...
  56. ncbi request reprint Difficulties in the diagnosis of vertebral fracture in men: Agreement between doctors
    Jacques Fechtenbaum
    Paris Descartes University, Rheumatology Department, Cochin Hospital, 27, rue du Faubourg St Jacques, 75014 Paris, France Electronic address
    Joint Bone Spine 81:169-74. 2014
    ..The agreement for vertebral fracture (VF) diagnosis in men, between doctors is poor...
  57. ncbi request reprint Effect of alendronate on HIV-associated osteoporosis: a randomized, double-blind, placebo-controlled, 96-week trial (ANRS 120)
    Sylvie Rozenberg
    AP HP, Groupe Hospitalier Pitie Salpetriere, Service de Rhumatologie, Paris, France
    AIDS Res Hum Retroviruses 28:972-80. 2012
    ..1% (95% CI 2.8 to 9.3); p=0.0003]. Alendronate 70 mg weekly for 96 weeks improves BMD in HIV-1-infected patients on antiretroviral therapy...
  58. doi request reprint Monitoring of bone turnover markers does not improve persistence with ibandronate treatment
    Christian Roux
    Service de Rhumatologie, Paris Descartes University, Hopital Cochin, 27, rue du Faubourg Saint Jacques, 75014 Paris, France
    Joint Bone Spine 79:389-92. 2012
    ..To assess if the use of biological marker of bone resorption (CTX) feedback is a mean to improve persistence on monthly oral ibandronate...
  59. doi request reprint The DESIR cohort: a 10-year follow-up of early inflammatory back pain in France: study design and baseline characteristics of the 708 recruited patients
    Maxime Dougados
    Paris Descartes University, Medicine Faculty, Rheumatology B Department, Paris 14, France
    Joint Bone Spine 78:598-603. 2011
    ....
  60. ncbi request reprint What is the role of DXA, QUS and bone markers in fracture prediction, treatment allocation and monitoring?
    Karine Briot
    Departement de Rhumatologie, Hopital Cochin, 27 rue du Faubourg St Jacques, 75014 Paris, France
    Best Pract Res Clin Rheumatol 19:951-64. 2005
    ..Biochemical markers of bone remodelling can be useful for both prediction of fracture risk and monitoring of treatment if sources of variability are controlled...
  61. pmc Accuracy of patient-reported height loss and risk factors for height loss among postmenopausal women
    Karine Briot
    Department of Rheumatology, Hôpital Cochin and Université Paris Descartes, Paris, France
    CMAJ 182:558-62. 2010
    ..We undertook this study to compare reported and measured loss of height among post-menopausal women in a primary care setting. We also analyzed the determinants of this height loss...
  62. doi request reprint Prevalence and features of osteoporosis in the French general population: the Instant study
    Eric Lespessailles
    Rheumatology Department, Orléans University Hospital, 45000 Orléans, France
    Joint Bone Spine 76:394-400. 2009
    ..To determine the prevalence of diagnosed osteoporosis, the extent of treatment use and the incidence of fracture in a representative sample of the French general population...
  63. pmc Strontium ranelate reduces the risk of vertebral fracture in young postmenopausal women with severe osteoporosis
    C Roux
    Departement de Rhumatologie, AP HP Hôpital Cochin, University Paris Descartes, Paris 75014, France
    Ann Rheum Dis 67:1736-8. 2008
    ..Strontium ranelate efficacy against vertebral fractures is presently assessed in a subset of women aged 50-65 years...
  64. pmc Increase in bone mineral density of patients with spondyloarthropathy treated with anti-tumour necrosis factor alpha
    F Allali
    Rheumatology Department, Rene Descartes University, Cochin Hospital, Paris, France
    Ann Rheum Dis 62:347-9. 2003
    ..To determine the changes in bone mineral density (BMD) in patients with spondyloarthropathy (SpA) treated with infliximab...
  65. ncbi request reprint Evaluation of the efficacy of etidronate therapy in preventing glucocorticoid-induced bone loss in patients with inflammatory rheumatic diseases. A randomized study
    B Cortet
    Rheumatology Department, Lille Teaching Hospital, France
    Rev Rhum Engl Ed 66:214-9. 1999
    ..Etidronate prevents glucocorticoid-induced lumbar spine bone loss in patients with rheumatoid arthritis, polymyalgia rheumatica, or giant cell arteritis...
  66. ncbi request reprint Long-term effects of infliximab on bone and cartilage turnover markers in patients with rheumatoid arthritis
    F Chopin
    INSERM U890, Rheumatology Department, University Hospital of St Etienne, France
    Ann Rheum Dis 67:353-7. 2008
    ..Therefore, we tested the hypothesis that administration of infliximab, an anti-TNFalpha drug in the treatment of RA, would modulate systemic and local bone resorption and reduce cartilage degradation...
  67. ncbi request reprint Benefits of pamidronate in children with osteogenesis imperfecta: an open prospective study
    Veronique Forin
    Service d Orthopédie Pédiatrique, Hopital Armand Trousseau, Assistance Publique Hopitaux de Paris, Universite Paris VI, Paris, France
    Joint Bone Spine 72:313-8. 2005
    ..To study the efficacy of pamidronate in children with osteogenesis imperfecta (OI)...
  68. ncbi request reprint Discrimination of osteoporotic patients with quantitative ultrasound using imaging or non-imaging device
    Geraldine Falgarone
    Centre d Evaluation des Maladies Osseuses, Institut de Rhumatologie, Hopital Cochin, Universite Rene Descartes, 27, rue du Faubourg St Jacques, 75014 Paris, France
    Joint Bone Spine 71:419-23. 2004
    ..The aim of this study was to compare the clinical utility of QUS parameters measured using imaging and non-imaging devices in the discrimination of osteoporotic patients...
  69. ncbi request reprint Practice patterns in outpatient rheumatology: a pilot evaluation of medical file content
    Jacques Fechtenbaum
    Rheumatology Department B, Cochin Teaching Hospital, AP HP, and René Descartes Paris V University, Paris, France
    Joint Bone Spine 74:171-4. 2007
    ..Subsequently, one of the RHEVER members investigated whether these recommendations were followed by RHEVER participants at a teaching hospital...
  70. ncbi request reprint Drug-induced osteoporosis: beyond glucocorticoids
    Karine Briot
    Department of Rheumatology, Cochin Hospital, 27 rue du Faubourg St Jacques, 75014 Paris, France
    Curr Rheumatol Rep 10:102-9. 2008
    ..Strong evidence points to gonadotropin-releasing hormone agonists, aromatase inhibitors, and antiepileptic drugs. Further studies are necessary to confirm the deleterious effect of other treatments on bone...
  71. ncbi request reprint Changes in body composition during post-menopausal hormone therapy: a 2 year prospective study
    A Arabi
    Centre d Evaluation des Maladies Osseuses, Departement de Rhumatologie, Hopital Cochin, Universite Rene Descartes, Paris, France
    Hum Reprod 18:1747-52. 2003
    ..Post-menopausal hormone therapy (pHT) induces changes in both body composition and bone mineral density (BMD)...
  72. doi request reprint Clinical utility of serum bone turnover markers in postmenopausal osteoporosis therapy monitoring: a systematic review
    Thomas Funck-Brentano
    Paris Descartes University, Cochin Hospital, Department of Rheumatology B, Paris, France
    Semin Arthritis Rheum 41:157-69. 2011
    ....
  73. ncbi request reprint Bone mineral measurements in mice: comparison of two devices
    Sami Kolta
    Rheumatology Department, Cochin Hospital, Assistance Publique, Hôpitaux de Paris René Descartes University, Paris, France
    J Clin Densitom 6:251-8. 2003
    ..We concluded that bone density and bone-density changes in mice can be measured precisely in vivo using the Hologic and Piximus devices; the latter being able to measure the whole body BMD with good precision...
  74. ncbi request reprint Segmentation of quantitative ultrasonographic images of the calcaneus using elastic deformation of the flexible Fourier contour
    Pascal Laugier
    Laboratoire d Imagerie Parametrique, Unite Mixte de Recherche, Centre National de la Recherche Scientifique 7623, Universite Paris VI, Paris, France
    J Ultrasound Med 23:693-9. 2004
    ..This study investigated a new technique for automatic model-based segmentation of broadband ultrasound attenuation (BUA) images of the calcaneus. We determined whether this technique was able to improve osteoporotic fracture discrimination...
  75. ncbi request reprint Predictors of compliance with a home-based exercise program added to usual medical care in preventing postmenopausal osteoporosis: an 18-month prospective study
    M A Mayoux-Benhamou
    Rehabilitation Department, Cochin Hospital, Assistance Publique Hopitaux de Paris, Rene Descartes University, F 75014 Paris Cedex, France
    Osteoporos Int 16:325-31. 2005
    ..10 to 1.16). Despite the addition of an educational session to usual medical care to inform participants about the benefits of exercise, only a minority of postmenopausal women adhered to a home-based exercise program after 18 months...
  76. ncbi request reprint Reporting of vertebral fractures on spine X-rays
    J Fechtenbaum
    Department of Rheumatology, Paris 5 University AP HP Cochin Hospital, 27 rue du Faubourg, Saint Jacques, 75014, Paris, France
    Osteoporos Int 16:1823-6. 2005
    ..As a consequence, patients who require treatment to reduce fracture risk are not being properly identified...
  77. ncbi request reprint Persistence with teriparatide in postmenopausal osteoporosis; impact of a patient education and follow-up program: the French experience
    K Briot
    Paris Descartes University, Rheumatology Department Cochin Hospital, Paris, France
    Osteoporos Int 20:625-30. 2009
    ..Analysis showed that the persistence rate was 81.5% for women who follow the program, higher than for existing oral antiresorptive treatments...
  78. ncbi request reprint Three-dimensional X-ray absorptiometry (3D-XA): a method for reconstruction of human bones using a dual X-ray absorptiometry device
    S Kolta
    Rheumatology Department, Cochin Hospital, Assistance Publique, Hôpitaux de Paris Université René Descartes, Paris, France
    Osteoporos Int 16:969-76. 2005
    ..It has good accuracy and reproducibility in the present study on cadaveric femurs. In vivo prospective studies are needed to evaluate its discriminating potential on hip fracture risk prediction...
  79. ncbi request reprint One year comparison between two add-back therapies in patients treated with a GnRH agonist for symptomatic endometriosis: a randomized double-blind trial
    H Fernandez
    Service de Gynecologie Obstetrique, Hopital Antoine Beclere, AP HP, 92141 Clamart, Paris, France
    Hum Reprod 19:1465-71. 2004
    ..The optimal combination for long-term treatments with safe metabolic profile remains questionable. A norprogesterone derivative, promegestone, was assessed for the first time in a double-blind trial...
  80. ncbi request reprint Vertebral dimensions as risk factor of vertebral fracture in osteoporotic patients: a systematic literature review
    A Ruyssen-Witrand
    Rheumatology B Department, Paris Rene Descartes University, Medicine Faculty AP HP, Cochin Hospital, Paris, France
    Osteoporos Int 18:1271-8. 2007
    ..Analysis showed that patients with vertebral fractures have smaller non-fractured vertebrae than patients without fractures. Vertebral size is an independent risk factor of vertebral fractures...
  81. ncbi request reprint Infliximab in spondylarthropathy--influence on bone density
    E Demis
    Rheumatology Department, Rene Descartes University, Cochin Hospital, Paris, France
    Clin Exp Rheumatol 20:S185-6. 2002
    ..There was an increase in osteocalcin between baseline and week 6. These data suggest a benefit of anti-TNFalpha therapy on BMD in patients with SpA, may be through an uncoupling effect on bone cells...
  82. doi request reprint Osteoporosis and mortality
    Ariane Leboime
    Service de Rhumatologie B, Universite Paris Descartes, Hopital Cochin, 27 rue du Faubourg Saint Jacques, Paris, France
    Joint Bone Spine 77:S107-12. 2010
    ..Here, we will review the main data linking osteoporotic fractures overall (as opposed to hip fractures only) and mortality...
  83. ncbi request reprint Statins in rheumatology
    Martin Soubrier
    Rheumatology Department, G Montpied Hospital, Place H Dunant, BP 69, 63003 Clermont Ferrand, France
    Joint Bone Spine 73:159-68. 2006
    ..When these show dyslipidemia, statin therapy should be started according to current recommendations...
  84. doi request reprint Hormonal deprivation therapy-induced osteoporosis in postmenopausal women with breast cancer
    Mirieme Ghazi
    Pairs Descartes University, Rheumatology Department, Cochin Hospital, Paris, France
    Best Pract Res Clin Rheumatol 23:805-11. 2009
    ..A comprehensive assessment of risk of fractures must be performed at the initiation of an AI therapy. Antiresorptive drugs (i.e., bisphosphonates and denosumab) are effective for bone loss prevention and treatment in these patients...
  85. doi request reprint Effect of a switch of aromatase inhibitors on musculoskeletal symptoms in postmenopausal women with hormone-receptor-positive breast cancer: the ATOLL (articular tolerance of letrozole) study
    Karine Briot
    Rheumatology Department, Cochin Hospital, Rheumatology Department, Paris Descartes University, 27 rue Faubourg Saint Jacques, 75014, Paris, France
    Breast Cancer Res Treat 120:127-34. 2010
    ..04). This study shows that in patients intolerant to one AI, switching to another agent allows a higher proportion of patients to continue the therapy and maximize hormonal adjuvant therapy and disease outcome benefits...
  86. ncbi request reprint Inverse relationship between vertebral fractures and spine osteoarthritis in postmenopausal women with osteoporosis
    C Roux
    Paris Descartes University, Cochin Hospital, Rheumatology Department, 27, rue du Faubourg St Jacques 75014 Paris, France
    Ann Rheum Dis 67:224-8. 2008
    ..The aim of this study was to check this hypothesis in postmenopausal women with osteoporosis...
  87. ncbi request reprint [Prevention and treatment of steroid-induced osteoporosis]
    C Roux
    Universite Paris Descartes, Faculte de Medecine, Assistance Publique Hopitaux de Paris, Hopital Cochin, Service de Rhumatologie, 27, rue du Faubourg Saint Jacques, 75014 Paris, France
    Ann Endocrinol (Paris) 67:162-5. 2006
  88. ncbi request reprint In vivo 3D reconstruction of human vertebrae with the three-dimensional X-ray absorptiometry (3D-XA) method
    S Kolta
    Paris Descartes University, Medicine Faculty, UPRES EA 4058, AP HP, Cochin Hospital, Paris, France
    Osteoporos Int 19:185-92. 2008
    ..This new technique, called 3D-XA (three-dimensional X-ray absorptiometry), allows the direct measurement of geometric parameters of the vertebrae with a good accuracy and precision...
  89. ncbi request reprint The severity of vertebral fractures and health-related quality of life in osteoporotic postmenopausal women
    J Fechtenbaum
    Department of Rheumatology, Descartes University of Paris Faculty of Medicine, Hopital Cochin, 27 rue du Faubourg Saint Jacques, 75014, Paris, France
    Osteoporos Int 16:2175-9. 2005
    ..Treating women with prevalent fractures may avoid a further decrease in their quality of life...
  90. doi request reprint Spinal deformity index (SDI) is a good predictor of incident vertebral fractures
    S Kerkeni
    Cochin Hospital, Rheumatology Department, Paris Descartes University, Paris, France
    Osteoporos Int 20:1547-52. 2009
    ..It is a predictor of the risk of sustaining incident vertebral fracture. This quantification must be taken into account to improve management of patients...
  91. ncbi request reprint [Vertebral fractures]
    Christian Roux
    Universite Paris Descartes, Faculte de Medecine, AP HP, Hopital Cochin, Service de Rhumatologie, 75014 Paris
    Rev Prat 62:181-5. 2012
    ..They are a strong risk factor for sustaining other fractures, including hip fractures. There is a high level of evidence for efficacy of antiosteoporotic treatments in post-menopausal patients with osteoporosis and vertebral fractures...
  92. ncbi request reprint Septic knee arthritis after intra-articular hyaluronate injection. Two case reports
    Christine Albert
    Rheumatology Department, Archet 1 Teaching Hospital, CHU de Nice, 151 rte St Antoine de Ginestiére, BP 3079, 06202 Nice Cedex 3, France
    Joint Bone Spine 73:205-7. 2006
    ..Faultless aseptic technique is essential when administering hyaluronate viscosupplementation. Patients should be informed of the risk of septic arthritis...
  93. ncbi request reprint Ultrasonic backscatter and transmission parameters at the os calcis in postmenopausal osteoporosis
    C Roux
    , Hĵpital Cochin, , Paris, France
    J Bone Miner Res 16:1353-62. 2001
    ..However, BUB evaluation, which does not require two transducers and may be implemented in conventional reflection mode systems, warrants further studies...
  94. doi request reprint Increase in vertebral body size in postmenopausal women with osteoporosis
    K Briot
    Paris Descartes University, Rheumatology Department, Cochin Hospital, Paris, France
    Bone 47:229-34. 2010
    ..01). These prospective results demonstrate that vertebral body dimensions increase over 3 years in women with postmenopausal osteoporosis...
  95. ncbi request reprint Bone mineral density assessment using the EOS low-dose X-ray device: a feasibility study
    E Sapin
    Laboratoire de Biomecanique, LBM, Arts et Metier ParisTech, CNRS, Paris, France
    Proc Inst Mech Eng H 222:1263-71. 2008
    ..The reproducibility of the method of assessment is equal to 0.95 per cent. The EOS system is accurate for ex-vivo BMD assessments, which is promising regarding the use of this new system to predict vertebral strength...
  96. ncbi request reprint [Osteoporosis]
    Christian Roux
    Service de Rhumatologie, Universite Paris Descartes, Hopital Cochin, 75014 Paris
    Rev Prat 56:673-7. 2006
  97. ncbi request reprint [Management of osteoporosis: room for improvment]
    Christian Roux
    Hopital Cochin, 27, rue du Faubourg St Jacques, 75679 Paris Cedex 14
    Bull Acad Natl Med 194:1483-8; discussion 1488-91. 2010
    ..Several drugs have shown that they are able to decrease the risk of fracture, providing persistence and compliance. Non pharmacological approach (including nutrition and physical activity) is part of optimal management of osteoporosis...
  98. ncbi request reprint Bone-resorbing cytokines from peripheral blood mononuclear cells after hormone replacement therapy: a longitudinal study
    O Bernard-Poenaru
    INSERM U349, , Paris, France
    Osteoporos Int 12:769-76. 2001
    ..In conclusion, our data indicate that non-adherent PBMC could mediate the response to HRT. HRT may exert its action indirectly via noncirculating cells, as suggested by the absence of an in vitro effect...
  99. ncbi request reprint Short-term protein and energy supplementation activates nitrogen kinetics and accretion in poorly nourished elderly subjects
    C Bos
    Institut National de la Recherche Agronomique INRA, Unité de Nutrition Humaine et de Physiologie Intestinale, Institut National Agronomique Paris Grignon INA PG, Paris, France
    Am J Clin Nutr 71:1129-37. 2000
    ..However, there are few data on the response to such dietary changes in malnourished elderly subjects, despite important medical implications in this population...
  100. ncbi request reprint Automated percutaneous lumbar discectomy versus chemonucleolysis in the treatment of sciatica. A randomized multicenter trial
    M Revel
    Department of Rheumatology, , Paris, France
    Spine (Phila Pa 1976) 18:1-7. 1993
    ..The results of this trial confirm previous controlled studies on chemonucleolysis and suggest that controlled studies should be carried out before automated percutaneous discectomy can be considered a useful intervention...
  101. ncbi request reprint [Biochemical markers of bone remodeling]
    K Briot
    Service de Rhumatologie, Hôpital Cochin APHP, Universite Paris Descartes, France
    Gynecol Obstet Fertil 33:1009-13. 2005
    ..Their use in clinical practice is difficult: choice of the most appropriate bone marker, relevance of changes, and may require the specialist's opinion...