Francois Rouet

Summary

Country: France

Publications

  1. doi In-house HIV-1 RNA real-time RT-PCR assays: principle, available tests and usefulness in developing countries
    Francois Rouet
    Laboratoire de Virologie, Centre Muraz, BP390 Bobo Dioulasso 01, Burkina Faso
    Expert Rev Mol Diagn 8:635-50. 2008
  2. pmc Virological failure rates and HIV-1 drug resistance patterns in patients on first-line antiretroviral treatment in semirural and rural Gabon
    Florian Liegeois
    Laboratoire de Retrovirologie, CIRMF, BP769, Franceville, Gabon
    J Int AIDS Soc 15:17985. 2012
  3. pmc Loss of memory CD4+ T-cells in semi-wild mandrills (Mandrillus sphinx) naturally infected with species-specific simian immunodeficiency virus SIVmnd-1
    Edward J D Greenwood
    University of Cambridge, Department of Veterinary Medicine, Cambridge CB3 0ES, UK
    J Gen Virol 95:201-12. 2014
  4. pmc New STLV-3 strains and a divergent SIVmus strain identified in non-human primate bushmeat in Gabon
    Florian Liegeois
    UMI 233, Trans VIH MI, Recherches Translationnelles sur le VIH et les Maladies Infectieuses Institut de Recherche pour le Développement IRD, University of Montpellier 1, Montpellier, France
    Retrovirology 9:28. 2012
  5. doi Current challenges to viral load testing in the context of emerging genetic diversity of HIV-1
    Francois Rouet
    Laboratoire de Retrovirologie, Centre International de Recherches Medicales de Franceville CIRMF, BP 769, Franceville, Gabon, France 241 677 092 096 241 677 295
    Expert Opin Med Diagn 5:183-202. 2011
  6. pmc Long-term virological, immunological and mortality outcomes in a cohort of HIV-infected female sex workers treated with highly active antiretroviral therapy in Africa
    Charlotte Huet
    London School of Hygiene and Tropical Medicine LSHTM, London, UK
    BMC Public Health 11:700. 2011
  7. pmc 18-month occurrence of severe events among early diagnosed HIV-infected children before antiretroviral therapy in Abidjan, Côte d'Ivoire: a cohort study
    Jérôme Harambat
    INSERM, Unité 897, Bordeaux, France
    BMC Public Health 8:169. 2008
  8. ncbi Long-term survival and immuno-virological response of African HIV-1-infected children to highly active antiretroviral therapy regimens
    Francois Rouet
    Centre de Diagnostic et de Recherches sur le SIDA CeDReS, CHU de Treichville, Cote d Ivoire
    AIDS 20:2315-9. 2006
  9. ncbi The measurement of HIV-1 viral load in resource-limited settings: how and where?
    Francois Rouet
    Laboratoire de Virologie, Centre Muraz, Bobo Dioulasso, Burkina Faso, West Africa
    Clin Lab 53:135-48. 2007
  10. ncbi Impact of HIV-1 genetic diversity on plasma HIV-1 RNA Quantification: usefulness of the Agence Nationale de Recherches sur le SIDA second-generation long terminal repeat-based real-time reverse transcriptase polymerase chain reaction test
    Francois Rouet
    Laboratoire de Virologie, Centre Muraz, BP 390 Bobo Dioulasso 01, Burkina Faso
    J Acquir Immune Defic Syndr 45:380-8. 2007

Detail Information

Publications42

  1. doi In-house HIV-1 RNA real-time RT-PCR assays: principle, available tests and usefulness in developing countries
    Francois Rouet
    Laboratoire de Virologie, Centre Muraz, BP390 Bobo Dioulasso 01, Burkina Faso
    Expert Rev Mol Diagn 8:635-50. 2008
    ..The LTR-based HIV-1 RNA RT-qPCR assay has been evaluated by several groups under the auspices of the Agence Nationale de Recherches sur le SIDA et les hépatites virales B et C. It exists now as a complete standardized commercial test...
  2. pmc Virological failure rates and HIV-1 drug resistance patterns in patients on first-line antiretroviral treatment in semirural and rural Gabon
    Florian Liegeois
    Laboratoire de Retrovirologie, CIRMF, BP769, Franceville, Gabon
    J Int AIDS Soc 15:17985. 2012
    ..In Gabon (central Africa), no study has yet reported the virological effectiveness of initial ART given through routine HIV care...
  3. pmc Loss of memory CD4+ T-cells in semi-wild mandrills (Mandrillus sphinx) naturally infected with species-specific simian immunodeficiency virus SIVmnd-1
    Edward J D Greenwood
    University of Cambridge, Department of Veterinary Medicine, Cambridge CB3 0ES, UK
    J Gen Virol 95:201-12. 2014
    ..STLVmnd-1 infection also had significant effects on some markers relevant to understanding SIV infection and thus should be considered in studies of SIV infection of African primates where present. ..
  4. pmc New STLV-3 strains and a divergent SIVmus strain identified in non-human primate bushmeat in Gabon
    Florian Liegeois
    UMI 233, Trans VIH MI, Recherches Translationnelles sur le VIH et les Maladies Infectieuses Institut de Recherche pour le Développement IRD, University of Montpellier 1, Montpellier, France
    Retrovirology 9:28. 2012
    ..We conducted a pilot study on 63 blood and/or tissues samples derived from NHP bushmeat seized by the competent authorities in different locations across the country...
  5. doi Current challenges to viral load testing in the context of emerging genetic diversity of HIV-1
    Francois Rouet
    Laboratoire de Retrovirologie, Centre International de Recherches Medicales de Franceville CIRMF, BP 769, Franceville, Gabon, France 241 677 092 096 241 677 295
    Expert Opin Med Diagn 5:183-202. 2011
    ..The large-scale implementation of HIV-1 VL testing is urgently required in the developing world to change HIV infection from a likely death sentence into a manageable chronic infection, as done in Northern countries...
  6. pmc Long-term virological, immunological and mortality outcomes in a cohort of HIV-infected female sex workers treated with highly active antiretroviral therapy in Africa
    Charlotte Huet
    London School of Hygiene and Tropical Medicine LSHTM, London, UK
    BMC Public Health 11:700. 2011
    ....
  7. pmc 18-month occurrence of severe events among early diagnosed HIV-infected children before antiretroviral therapy in Abidjan, Côte d'Ivoire: a cohort study
    Jérôme Harambat
    INSERM, Unité 897, Bordeaux, France
    BMC Public Health 8:169. 2008
    ....
  8. ncbi Long-term survival and immuno-virological response of African HIV-1-infected children to highly active antiretroviral therapy regimens
    Francois Rouet
    Centre de Diagnostic et de Recherches sur le SIDA CeDReS, CHU de Treichville, Cote d Ivoire
    AIDS 20:2315-9. 2006
    ..In Africa, facing the scaling-up of HAART, there is an urgent need to monitor accurately the long-term benefits of these lifelong treatments...
  9. ncbi The measurement of HIV-1 viral load in resource-limited settings: how and where?
    Francois Rouet
    Laboratoire de Virologie, Centre Muraz, Bobo Dioulasso, Burkina Faso, West Africa
    Clin Lab 53:135-48. 2007
    ..In addition, different strategies for HIV-1 viral load monitoring are discussed according to laboratory facilities in resource-constrained settings...
  10. ncbi Impact of HIV-1 genetic diversity on plasma HIV-1 RNA Quantification: usefulness of the Agence Nationale de Recherches sur le SIDA second-generation long terminal repeat-based real-time reverse transcriptase polymerase chain reaction test
    Francois Rouet
    Laboratoire de Virologie, Centre Muraz, BP 390 Bobo Dioulasso 01, Burkina Faso
    J Acquir Immune Defic Syndr 45:380-8. 2007
    ..Addressing HIV-1 diversity, continual monitoring of HIV-1 RNA assays, together with molecular epidemiology studies, is required to improve the accuracy of all HIV RNA assays...
  11. doi Frequent occurrence of chronic hepatitis B virus infection among West African HIV type-1-infected children
    Francois Rouet
    Centre de Diagnostic et de Recherches sur le SIDA, Centre Hospitalier Universitaire CHU de Treichville, Abidjan, Ivory Coast
    Clin Infect Dis 46:361-6. 2008
    ..The aim of this study, conducted in Ivory Coast, was to evaluate the prevalence and evolution of viral hepatitis in children coinfected with human immunodeficiency virus type 1 (HIV-1)...
  12. doi Relationship of CD4+ T-cell counts and plasma HIV-1 RNA levels with serological HBeAg/anti-HBe patterns obtained in West-African HBV-HIV-1-co-infected children
    Francois Rouet
    CeDReS, CHU de Treichville, Abidjan, Cote d Ivoire
    J Trop Pediatr 55:409-12. 2009
    ..01) higher in specimens HBV DNA-positive (4.47 and 4.30 log(10)/ml, respectively) vs. HBV DNA-negative (3.43 log(10)/ml). HIV-1 has a significant impact on CHB acquired in childhood...
  13. doi Comparison of the Generic HIV Viral Load assay with the Amplicor HIV-1 monitor v1.5 and Nuclisens HIV-1 EasyQ v1.2 techniques for plasma HIV-1 RNA quantitation of non-B subtypes: the Kesho Bora preparatory study
    Francois Rouet
    Laboratoire de Virologie, Centre Muraz, Bobo Dioulasso, Burkina Faso
    J Virol Methods 163:253-7. 2010
    ..Due to its low cost (approximately 10 US $/test), this assay performed with open real-time PCR instruments is now used routinely in the Kesho Bora trial and may be recommended in other African settings...
  14. ncbi CD4 percentages and total lymphocyte counts as early surrogate markers for pediatric HIV-1 infection in resource-limited settings
    Francois Rouet
    Centre de Diagnostic et de Recherches sur le SIDA CeDReS, Centre Hospitalier Universitaire de Treichville, Abidjan, Cote d Ivoire
    J Trop Pediatr 52:346-54. 2006
    ..CD4% should be further evaluated under field conditions for the diagnosis of pediatric HIV-1 infection and the monitoring of pediatric antiretroviral therapy...
  15. ncbi Primary HIV-1 infection in African children infected through breastfeeding
    Francois Rouet
    CeDReS, CHU de Treichville, Abidjan, Cote d Ivoire
    AIDS 16:2303-9. 2002
    ..To describe acute retroviral syndrome and associated primary viraemia in African children infected with HIV-1 through breastfeeding...
  16. ncbi HBV and HCV prevalence and viraemia in HIV-positive and HIV-negative pregnant women in Abidjan, Côte d'Ivoire: the ANRS 1236 study
    Francois Rouet
    CeDReS, Programme PAC CI, CHU de Treichville, Abidjan, Ivory Coast
    J Med Virol 74:34-40. 2004
    ..We propose an accurate and cost-efficient algorithm for HCV diagnosis in Africa...
  17. pmc Antiretroviral treatment and prevention of peripartum and postnatal HIV transmission in West Africa: evaluation of a two-tiered approach
    Besigin Tonwe-Gold
    MTCT Plus Programme, ACONDA, Abidjan, Cote d Ivoire
    PLoS Med 4:e257. 2007
    ....
  18. ncbi Variation of CD4 count and percentage during pregnancy and after delivery: implications for HAART initiation in resource-limited settings
    Didier K Ekouevi
    Programme PACCI, Abidjan, Cote d Ivoire, INSERM, Unité 593, Bordeaux, France
    AIDS Res Hum Retroviruses 23:1469-74. 2007
    ..To accurately target the most appropriate time to start HAART, the CD4 percentage could be more reliable than the absolute count in sub-Saharan African pregnant women...
  19. pmc Transfer and evaluation of an automated, low-cost real-time reverse transcription-PCR test for diagnosis and monitoring of human immunodeficiency virus type 1 infection in a West African resource-limited setting
    Francois Rouet
    Centre de Diagnostic et de Recherches sur le SIDA, Abidjan, Cote d Ivoire
    J Clin Microbiol 43:2709-17. 2005
    ..The TaqMan real-time PCR (12 dollars per test) is now routinely used to monitor HIV-1 infection in our laboratory. This technology should be further evaluated in limited-resource countries where strains other than CRF02 are prevalent...
  20. pmc Immune status and uptake of antiretroviral interventions to prevent mother-to-child transmission of HIV-1 in Africa
    Didier K Ekouevi
    Projet ANRS 1201 1202 Ditrame Plus and CeDReS, Programme PACCI, Abidjan, Cote d Ivoire, France
    J Acquir Immune Defic Syndr 36:755-7. 2004
    ..425/mm3; P=0.47). The overall uptake of the intervention (31.9%) appeared to be independent of the maternal immune status...
  21. ncbi Pediatric viral human immunodeficiency virus type 1 RNA levels, timing of infection, and disease progression in African HIV-1-infected children
    Francois Rouet
    CeDReS, Programme PAC CI, CHU de Treichville, Abidjan, Cote d Ivoire
    Pediatrics 112:e289. 2003
    ..To describe plasma human immunodeficiency virus type 1 (HIV-1) RNA levels in African HIV-1-infected children in relation to the timing of infection and disease progression...
  22. ncbi Medium-term survival, morbidity and immunovirological evolution in HIV-infected adults receiving antiretroviral therapy, Abidjan, Côte d'Ivoire
    Catherine Seyler
    Programme PAC CI, Abidjan, Cote d Ivoire
    Antivir Ther 8:385-93. 2003
    ..To evaluate survival, morbidity, and CD4 and viral load (VL) evolution in HIV-infected adults receiving antiretroviral therapy (ART) in Côte d'Ivoire...
  23. pmc Anthropometric and immunological success of antiretroviral therapy and prediction of virological success in west African adults
    Eugene Messou
    Programme PAC, CI, Abidjan, Cote d Ivoire
    Bull World Health Organ 86:435-42. 2008
    ..We assessed the gain or loss in body mass index (BMI), alone or in combination with the gain or loss in CD4+ T-cell count (CD4), as a tool for predicting the response to ART...
  24. pmc Field evaluation of a rapid human immunodeficiency virus (HIV) serial serologic testing algorithm for diagnosis and differentiation of HIV type 1 (HIV-1), HIV-2, and dual HIV-1-HIV-2 infections in West African pregnant women
    Francois Rouet
    Centre de Diagnostic et de Recherches sur le SIDA, CHU de Treichville, BP V3 Abidjan, Cote d Ivoire
    J Clin Microbiol 42:4147-53. 2004
    ..Even if they are rare, women identified by the Genie II assay as being infected with HIV-1 and HIV-2 mostly appeared to be infected only with HIV-2...
  25. ncbi Diagnosed tuberculosis during the follow-up of a cohort of human immunodeficiency virus-infected children in Abidjan, Côte d'Ivoire: ANRS 1278 study
    Narcisse Elenga
    Programme Enfant Yopougon, PACCI, Abidjan, Cote d Ivoire
    Pediatr Infect Dis J 24:1077-82. 2005
    ..Most data on tuberculosis in human immunodeficiency virus (HIV)-infected children in Africa come from hospital-based and cross-sectional studies...
  26. ncbi Tolerance and acceptability of an efavirenz-based regimen in 740 adults (predominantly women) in West Africa
    Christine Danel
    Programme PAC CI, Abidjan, Cote d Ivoire, France
    J Acquir Immune Defic Syndr 42:29-35. 2006
    ....
  27. ncbi Acceptability and uptake of a package to prevent mother-to-child transmission using rapid HIV testing in Abidjan, Côte d'Ivoire
    Didier K Ekouevi
    Project ANRS Ditrame Plus, Programme PACCI, Abidjan, Cote d Ivoire
    AIDS 18:697-700. 2004
  28. ncbi CD4-guided structured antiretroviral treatment interruption strategy in HIV-infected adults in west Africa (Trivacan ANRS 1269 trial): a randomised trial
    Christine Danel
    Programme PAC CI, Abidjan, Cote d Ivoire
    Lancet 367:1981-9. 2006
    ..We did a randomised trial of structured treatment interruption in Abidjan, Côte d'Ivoire...
  29. doi HIV-1 DNA in peripheral blood mononuclear cells is strongly associated with HIV-1 disease progression in recently infected West African adults
    Albert K Minga
    Programme PAC CI, Abidjan, Cote d Ivoire, France
    J Acquir Immune Defic Syndr 48:350-4. 2008
    ..To analyze the association between the HIV-1 DNA level in peripheral blood mononuclear cells (PBMCs) and disease progression in recently infected West African adults...
  30. ncbi Presence of key drug resistance mutations in isolates from untreated patients of Abidjan, Côte d'Ivoire: ANRS 1257 study
    Thomas d aquin Toni
    CIRBA, Abidjan, Cote d Ivoire
    AIDS Res Hum Retroviruses 19:713-7. 2003
    ..Compared to a previous study carried out by our group in 1997-2000 in a similar population of Abidjan, it seems that there is a dynamic process of resistance and that a survey will be necessary...
  31. ncbi Effect of perinatal zidovudine prophylaxis on the evolution of cell-free HIV-1 RNA in breast milk and on postnatal transmission
    Olivier Manigart
    Centre Muraz, 01BP390 Bobo Dioulasso, Burkina Faso, Cote d Ivoire
    J Infect Dis 190:1422-8. 2004
    ..The rebound in levels of HIV-1 RNA in breast milk after discontinuation of maternal antiretrovirals needs to be further explored--it may justify prolonging antiretroviral prophylaxis during the entire breast-feeding period...
  32. doi HIV type-1 group O infection in Gabon: low prevalence rate but circulation of genetically diverse and drug-resistant HIV type-1 group O strains
    Florian Liegeois
    Laboratoire de Retrovirologie, CIRMF Centre International de Recherches Médicales de Franceville, Franceville, Gabon
    AIDS Res Hum Retroviruses 29:1085-90. 2013
    ..Even if HIV-1/O infection is low in Gabon, an accurate diagnosis and a reliable virological follow-up are required in Central Africa to optimize ARV treatments of HIV-1/O-infected patients...
  33. pmc Pregnancy outcomes in women exposed to efavirenz and nevirapine: an appraisal of the IeDEA West Africa and ANRS Databases, Abidjan, Côte d'Ivoire
    Didier K Ekouevi
    Programme PAC CI, Abidjan, Cote d Ivoire
    J Acquir Immune Defic Syndr 56:183-7. 2011
    ..An increasing number of HIV-infected women become pregnant while receiving efavirenz (EFV). We compared the pregnancy outcomes of women exposed to EFV and to nevirapine (NVP) during the first trimester...
  34. ncbi Significant impact of non-B HIV-1 variants genetic diversity in Gabon on plasma HIV-1 RNA quantitation
    Augustin Mouinga-Ondeme
    Retrovirology Laboratory, CIRMF, Franceville, Gabon
    J Med Virol 86:52-7. 2014
    ..Further studies are required in the same area to confirm the presence of HIV-1 strains that are not amplified with at least two different viral load assays...
  35. pmc CD4+ T cells spontaneously producing human immunodeficiency virus type I in breast milk from women with or without antiretroviral drugs
    Diane Valea
    Laboratoire Virologie, Centre Muraz, Bobo Dioulasso, Burkina Faso
    Retrovirology 8:34. 2011
    ..This latter viral reservoir remains, however, to be fully explored. CD4+ T cell-associated virus production in breast milk was therefore investigated...
  36. doi Short communication: high natural polymorphism in the gag gene cleavage sites of non-B HIV type 1 isolates from Gabon
    Florian Liegeois
    Laboratoire de Retrovirologie, CIRMF, BP769, Franceville, Gabon
    AIDS Res Hum Retroviruses 29:1179-82. 2013
    ..In sub-Saharan Africa, further studies are definitively required to better understand the impact of gag mutations among subjects receiving second-line LPV/r-containing regimens (monotherapy or triple combinations)...
  37. pmc Low prevalence rate of indeterminate serological human immunodeficiency virus results among pregnant women from Burkina Faso, West Africa
    Dramane Kania
    Laboratoire de Virologie, Centre Muraz, Bobo Dioulasso, Burkina Faso
    J Clin Microbiol 48:1333-6. 2010
    ..As a consequence, such women with indeterminate results can reliably be considered negative when urgent clinical decisions (such as providing PMTCT prophylaxis) need to be taken...
  38. ncbi Cross-clade conservation of HIV type 1 Nef immunodominant regions recognized by CD8+ T cells of HIV type 1 CRF02_AG-infected Ivorian (West Africa)
    Andre Inwoley
    CeDReS PAC CI, CHU Treichville, Abidjan, Cote d Ivoire
    AIDS Res Hum Retroviruses 21:620-8. 2005
    ....
  39. doi A new strategy to improve the cost-effectiveness of human immunodeficiency virus, hepatitis B virus, hepatitis C virus, and syphilis testing of blood donations in sub-Saharan Africa: a pilot study in Burkina Faso
    Dramane Kania
    Laboratoire de Virologie, Centre Muraz, Bobo Dioulasso, Burkina Faso
    Transfusion 49:2237-40. 2009
    ..In Africa where blood-borne agents are highly prevalent, cheaper and feasible alternative strategies for blood donations testing are specifically required...
  40. doi Roles of clinical and subclinical reactivated herpes simplex virus type 2 infection and human immunodeficiency virus type 1 (HIV-1)-induced immunosuppression on genital and plasma HIV-1 levels
    N Nagot
    Centre Muraz, Burkina Faso
    J Infect Dis 198:241-9. 2008
    ....
  41. ncbi Do tests devised to detect recent HIV-1 infection provide reliable estimates of incidence in Africa?
    Charlotte Sakarovitch
    INSERM EMI 03 38, Institut de Santé Publique, Epidemiologie, et Développement ISPED, Universite Victor Segalen Bordeaux 2, Bordeaux, France
    J Acquir Immune Defic Syndr 45:115-22. 2007
    ..The authors conclude that none of the 4 methods could currently be used to estimate HIV-1 incidence routinely in Côte d'Ivoire but that further adaptations might enhance their accuracy...
  42. pmc Pharmacology and immuno-virologic efficacy of once-a-day HAART in African HIV-infected children: ANRS 12103 phase II trial
    Boubacar Nacro
    Department of Paediatrics, Centre Hospitalier Universitaire Souro Sanou, Bobo Dioulasso, Burkina Faso
    Bull World Health Organ 89:451-8. 2011
    ....