Research Topics
| Francois RouetSummaryCountry: France Publications
| Collaborators
|
Detail Information
Publications
In-house HIV-1 RNA real-time RT-PCR assays: principle, available tests and usefulness in developing countriesFrancois Rouet
Laboratoire de Virologie, Centre Muraz, BP390 Bobo Dioulasso 01, Burkina Faso
Expert Rev Mol Diagn 8:635-50. 2008..The LTR-based HIV-1 RNA RT-qPCR assay has been evaluated by several groups under the auspices of the Agence Nationale de Recherches sur le SIDA et les hépatites virales B et C. It exists now as a complete standardized commercial test...- Current challenges to viral load testing in the context of emerging genetic diversity of HIV-1Francois Rouet
Laboratoire de Retrovirologie, Centre International de Recherches Medicales de Franceville CIRMF, BP 769, Franceville, Gabon, France 241 677 092 096 241 677 295
Expert Opin Med Diagn 5:183-202. 2011..The large-scale implementation of HIV-1 VL testing is urgently required in the developing world to change HIV infection from a likely death sentence into a manageable chronic infection, as done in Northern countries... 
Long-term virological, immunological and mortality outcomes in a cohort of HIV-infected female sex workers treated with highly active antiretroviral therapy in AfricaCharlotte Huet
London School of Hygiene and Tropical Medicine LSHTM, London, UK
BMC Public Health 11:700. 2011....- 18-month occurrence of severe events among early diagnosed HIV-infected children before antiretroviral therapy in Abidjan, Côte d'Ivoire: a cohort studyJérôme Harambat
INSERM, Unité 897, Bordeaux, France
BMC Public Health 8:169. 2008.... - Relationship of CD4+ T-cell counts and plasma HIV-1 RNA levels with serological HBeAg/anti-HBe patterns obtained in West-African HBV-HIV-1-co-infected childrenFrancois Rouet
CeDReS, CHU de Treichville, Abidjan, Cote d Ivoire
J Trop Pediatr 55:409-12. 2009..01) higher in specimens HBV DNA-positive (4.47 and 4.30 log(10)/ml, respectively) vs. HBV DNA-negative (3.43 log(10)/ml). HIV-1 has a significant impact on CHB acquired in childhood... - Comparison of the Generic HIV Viral Load assay with the Amplicor HIV-1 monitor v1.5 and Nuclisens HIV-1 EasyQ v1.2 techniques for plasma HIV-1 RNA quantitation of non-B subtypes: the Kesho Bora preparatory studyFrancois Rouet
Laboratoire de Virologie, Centre Muraz, Bobo Dioulasso, Burkina Faso
J Virol Methods 163:253-7. 2010..Due to its low cost (approximately 10 US $/test), this assay performed with open real-time PCR instruments is now used routinely in the Kesho Bora trial and may be recommended in other African settings... - Frequent occurrence of chronic hepatitis B virus infection among West African HIV type-1-infected childrenFrancois Rouet
Centre de Diagnostic et de Recherches sur le SIDA, Centre Hospitalier Universitaire CHU de Treichville, Abidjan, Ivory Coast
Clin Infect Dis 46:361-6. 2008..The aim of this study, conducted in Ivory Coast, was to evaluate the prevalence and evolution of viral hepatitis in children coinfected with human immunodeficiency virus type 1 (HIV-1)... 
Impact of HIV-1 genetic diversity on plasma HIV-1 RNA Quantification: usefulness of the Agence Nationale de Recherches sur le SIDA second-generation long terminal repeat-based real-time reverse transcriptase polymerase chain reaction testFrancois Rouet
Laboratoire de Virologie, Centre Muraz, BP 390 Bobo Dioulasso 01, Burkina Faso
J Acquir Immune Defic Syndr 45:380-8. 2007..Addressing HIV-1 diversity, continual monitoring of HIV-1 RNA assays, together with molecular epidemiology studies, is required to improve the accuracy of all HIV RNA assays...- The measurement of HIV-1 viral load in resource-limited settings: how and where?Francois Rouet
Laboratoire de Virologie, Centre Muraz, Bobo Dioulasso, Burkina Faso, West Africa
Clin Lab 53:135-48. 2007..In addition, different strategies for HIV-1 viral load monitoring are discussed according to laboratory facilities in resource-constrained settings... - Long-term survival and immuno-virological response of African HIV-1-infected children to highly active antiretroviral therapy regimensFrancois Rouet
Centre de Diagnostic et de Recherches sur le SIDA CeDReS, CHU de Treichville, Cote d Ivoire
AIDS 20:2315-9. 2006..In Africa, facing the scaling-up of HAART, there is an urgent need to monitor accurately the long-term benefits of these lifelong treatments... - CD4 percentages and total lymphocyte counts as early surrogate markers for pediatric HIV-1 infection in resource-limited settingsFrancois Rouet
Centre de Diagnostic et de Recherches sur le SIDA CeDReS, Centre Hospitalier Universitaire de Treichville, Abidjan, Cote d Ivoire
J Trop Pediatr 52:346-54. 2006..CD4% should be further evaluated under field conditions for the diagnosis of pediatric HIV-1 infection and the monitoring of pediatric antiretroviral therapy... - HBV and HCV prevalence and viraemia in HIV-positive and HIV-negative pregnant women in Abidjan, Côte d'Ivoire: the ANRS 1236 studyFrancois Rouet
CeDReS, Programme PAC CI, CHU de Treichville, Abidjan, Ivory Coast
J Med Virol 74:34-40. 2004..We propose an accurate and cost-efficient algorithm for HCV diagnosis in Africa... - Variation of CD4 count and percentage during pregnancy and after delivery: implications for HAART initiation in resource-limited settingsDidier K Ekouevi
Programme PACCI, Abidjan, Cote d Ivoire, INSERM, Unité 593, Bordeaux, France
AIDS Res Hum Retroviruses 23:1469-74. 2007..To accurately target the most appropriate time to start HAART, the CD4 percentage could be more reliable than the absolute count in sub-Saharan African pregnant women... - Antiretroviral treatment and prevention of peripartum and postnatal HIV transmission in West Africa: evaluation of a two-tiered approachBesigin Tonwe Gold
MTCT Plus Programme, ACONDA, Abidjan, Cote d Ivoire
PLoS Med 4:e257. 2007.... - Primary HIV-1 infection in African children infected through breastfeedingFrancois Rouet
CeDReS, CHU de Treichville, Abidjan, Cote d Ivoire
AIDS 16:2303-9. 2002..To describe acute retroviral syndrome and associated primary viraemia in African children infected with HIV-1 through breastfeeding... - Immune status and uptake of antiretroviral interventions to prevent mother-to-child transmission of HIV-1 in AfricaDidier K Ekouevi
Projet ANRS 1201 1202 Ditrame Plus and CeDReS, Programme PACCI, Abidjan, Cote d Ivoire, France
J Acquir Immune Defic Syndr 36:755-7. 2004..425/mm3; P=0.47). The overall uptake of the intervention (31.9%) appeared to be independent of the maternal immune status... - Transfer and evaluation of an automated, low-cost real-time reverse transcription-PCR test for diagnosis and monitoring of human immunodeficiency virus type 1 infection in a West African resource-limited settingFrancois Rouet
Centre de Diagnostic et de Recherches sur le SIDA, Abidjan, Cote d Ivoire
J Clin Microbiol 43:2709-17. 2005..The TaqMan real-time PCR (12 dollars per test) is now routinely used to monitor HIV-1 infection in our laboratory. This technology should be further evaluated in limited-resource countries where strains other than CRF02 are prevalent... - Field evaluation of a rapid human immunodeficiency virus (HIV) serial serologic testing algorithm for diagnosis and differentiation of HIV type 1 (HIV-1), HIV-2, and dual HIV-1-HIV-2 infections in West African pregnant womenFrancois Rouet
Centre de Diagnostic et de Recherches sur le SIDA, CHU de Treichville, BP V3 Abidjan, Cote d Ivoire
J Clin Microbiol 42:4147-53. 2004..Even if they are rare, women identified by the Genie II assay as being infected with HIV-1 and HIV-2 mostly appeared to be infected only with HIV-2... - Anthropometric and immunological success of antiretroviral therapy and prediction of virological success in west African adultsEugene Messou
Programme PAC, CI, Abidjan, Cote d Ivoire
Bull World Health Organ 86:435-42. 2008..We assessed the gain or loss in body mass index (BMI), alone or in combination with the gain or loss in CD4+ T-cell count (CD4), as a tool for predicting the response to ART... - Pediatric viral human immunodeficiency virus type 1 RNA levels, timing of infection, and disease progression in African HIV-1-infected childrenFrancois Rouet
CeDReS, Programme PAC CI, CHU de Treichville, Abidjan, Cote d Ivoire
Pediatrics 112:e289. 2003..To describe plasma human immunodeficiency virus type 1 (HIV-1) RNA levels in African HIV-1-infected children in relation to the timing of infection and disease progression... - Tolerance and acceptability of an efavirenz-based regimen in 740 adults (predominantly women) in West AfricaChristine Danel
Programme PAC CI, Abidjan, Cote d Ivoire, France
J Acquir Immune Defic Syndr 42:29-35. 2006.... - HIV-1 DNA in peripheral blood mononuclear cells is strongly associated with HIV-1 disease progression in recently infected West African adultsAlbert K Minga
Programme PAC CI, Abidjan, Cote d Ivoire, France
J Acquir Immune Defic Syndr 48:350-4. 2008..To analyze the association between the HIV-1 DNA level in peripheral blood mononuclear cells (PBMCs) and disease progression in recently infected West African adults... - Effect of perinatal zidovudine prophylaxis on the evolution of cell-free HIV-1 RNA in breast milk and on postnatal transmissionOlivier Manigart
Centre Muraz, 01BP390 Bobo-Dioulasso, Burkina Faso, Cote d'Ivoire
J Infect Dis 190:1422-8. 2004..The rebound in levels of HIV-1 RNA in breast milk after discontinuation of maternal antiretrovirals needs to be further explored--it may justify prolonging antiretroviral prophylaxis during the entire breast-feeding period... - Pregnancy outcomes in women exposed to efavirenz and nevirapine: an appraisal of the IeDEA West Africa and ANRS Databases, Abidjan, Côte d'IvoireDidier K Ekouevi
Programme PAC CI, Abidjan, Cote d Ivoire
J Acquir Immune Defic Syndr 56:183-7. 2011..An increasing number of HIV-infected women become pregnant while receiving efavirenz (EFV). We compared the pregnancy outcomes of women exposed to EFV and to nevirapine (NVP) during the first trimester... - CD4+ T cells spontaneously producing human immunodeficiency virus type I in breast milk from women with or without antiretroviral drugsDiane Valea
Laboratoire Virologie, Centre Muraz, Bobo Dioulasso, Burkina Faso
Retrovirology 8:34. 2011..This latter viral reservoir remains, however, to be fully explored. CD4+ T cell-associated virus production in breast milk was therefore investigated... - Low prevalence rate of indeterminate serological human immunodeficiency virus results among pregnant women from Burkina Faso, West AfricaDramane Kania
Laboratoire de Virologie, Centre Muraz, Bobo Dioulasso, Burkina Faso
J Clin Microbiol 48:1333-6. 2010..As a consequence, such women with indeterminate results can reliably be considered negative when urgent clinical decisions (such as providing PMTCT prophylaxis) need to be taken... - Cross-clade conservation of HIV type 1 Nef immunodominant regions recognized by CD8+ T cells of HIV type 1 CRF02_AG-infected Ivorian (West Africa)Andre Inwoley
CeDReS PAC CI, CHU Treichville, Abidjan, Cote d Ivoire
AIDS Res Hum Retroviruses 21:620-8. 2005.... - A new strategy to improve the cost-effectiveness of human immunodeficiency virus, hepatitis B virus, hepatitis C virus, and syphilis testing of blood donations in sub-Saharan Africa: a pilot study in Burkina FasoDramane Kania
Laboratoire de Virologie, Centre Muraz, Bobo Dioulasso, Burkina Faso
Transfusion 49:2237-40. 2009..In Africa where blood-borne agents are highly prevalent, cheaper and feasible alternative strategies for blood donations testing are specifically required... - Roles of clinical and subclinical reactivated herpes simplex virus type 2 infection and human immunodeficiency virus type 1 (HIV-1)-induced immunosuppression on genital and plasma HIV-1 levelsN Nagot
Centre Muraz, Burkina Faso
J Infect Dis 198:241-9. 2008.... - Do tests devised to detect recent HIV-1 infection provide reliable estimates of incidence in Africa?Charlotte Sakarovitch
INSERM EMI 03 38, Institut de Santé Publique, Epidemiologie, et Développement ISPED, Universite Victor Segalen Bordeaux 2, Bordeaux, France
J Acquir Immune Defic Syndr 45:115-22. 2007..The authors conclude that none of the 4 methods could currently be used to estimate HIV-1 incidence routinely in Côte d'Ivoire but that further adaptations might enhance their accuracy... - Pharmacology and immuno-virologic efficacy of once-a-day HAART in African HIV-infected children: ANRS 12103 phase II trialBoubacar Nacro
Department of Paediatrics, Centre Hospitalier Universitaire Souro Sanou, Bobo Dioulasso, Burkina Faso
Bull World Health Organ 89:451-8. 2011.... - Virological failure rates and HIV-1 drug resistance patterns in patients on first-line antiretroviral treatment in semirural and rural GabonFlorian Liegeois
Laboratoire de Retrovirologie, CIRMF, BP769, Franceville, Gabon
J Int AIDS Soc 15:17985. 2012..In Gabon (central Africa), no study has yet reported the virological effectiveness of initial ART given through routine HIV care...