Stephane Marret

Summary

Affiliation: Rouen University Hospital
Country: France

Publications

  1. ncbi request reprint Antenatal magnesium sulphate neuroprotection in the preterm infant
    Stephane Marret
    Department of Neonatal Medicine, University Hospital, 1, rue de Germont, 76031, Rouen Cedex, France
    Semin Fetal Neonatal Med 12:311-7. 2007
  2. pmc Brain injury in very preterm children and neurosensory and cognitive disabilities during childhood: the EPIPAGE cohort study
    Stephane Marret
    Department of Neonatal Medicine, Rouen University Hospital and Region INSERM Team, ERI 28, Neovasc, Institute for Biomedical Research and Innovation, Rouen University, Rouen, France
    PLoS ONE 8:e62683. 2013
  3. doi request reprint Pathophysiology of cerebral palsy
    Stephane Marret
    Department of Neonatal Medicine and Centre of Child Functional Education, Rouen University Hospital, Rouen, France INSERM Region Team ERI 28, Rouen Institute for Medical Research and Innovation, School of Medicine, Rouen University, Rouen, France Electronic address
    Handb Clin Neurol 111:169-76. 2013
  4. ncbi request reprint Fetal and neonatal cerebral infarcts
    S Marret
    Department of Neonatal Medicine, Clinique de Pédiatrie et de Puériculture, Hopital Charles Nicolle, Rouen, France
    Biol Neonate 79:236-40. 2001
  5. ncbi request reprint Magnesium sulphate given before very-preterm birth to protect infant brain: the randomised controlled PREMAG trial*
    S Marret
    Department of Neonatal Medicine, Rouen University Hospital, Rouen, France
    BJOG 114:310-8. 2007
  6. ncbi request reprint Neonatal and 5-year outcomes after birth at 30-34 weeks of gestation
    Stephane Marret
    Department of Neonatal Medicine, Rouen University Hospital and Inserm Avenir Research Group, Institute for Biomedical Research, University of Rouen, Rouen, France
    Obstet Gynecol 110:72-80. 2007
  7. doi request reprint [Effect of magnesium sulphate on mortality and neurologic morbidity of the very-preterm newborn (of less than 33 weeks) with two-year neurological outcome: results of the prospective PREMAG trial]
    S Marret
    Service de pédiatrie néonatale et réanimation, hôpital universitaire de Rouen, 1 rue de Germont, Rouen Cedex, France
    Gynecol Obstet Fertil 36:278-88. 2008
  8. ncbi request reprint [Effects of maternal smoking during pregnancy on fetal brain development]
    S Marret
    Service de pédiatrie néonatale et réanimation, Hopital Charles Nicolle, CHU de Rouen, 76031 Rouen Cedex
    J Gynecol Obstet Biol Reprod (Paris) 34:3S230-3. 2005
  9. ncbi request reprint [Brain plasticity in preterm infant]
    S Marret
    Service de pédiatrie néonatale et réanimation, Hopital Charles Nicolle, CHU de Rouen, 76031 Rouen Cedex, France
    Arch Pediatr 14:519-21. 2007
  10. ncbi request reprint [Indications for early intervention in the prevention and management of neurodevelopmental disorders]
    S Marret
    Service de pédiatrie néonatale et réanimation, Hopital Charles Nicolle, CHU de Rouen, 76031 Rouen Cedex, France
    Arch Pediatr 11:611-3. 2004

Detail Information

Publications52

  1. ncbi request reprint Antenatal magnesium sulphate neuroprotection in the preterm infant
    Stephane Marret
    Department of Neonatal Medicine, University Hospital, 1, rue de Germont, 76031, Rouen Cedex, France
    Semin Fetal Neonatal Med 12:311-7. 2007
    ..The role for antenatal magnesium sulphate therapy as a neuroprotective agent for the preterm fetus is not yet established...
  2. pmc Brain injury in very preterm children and neurosensory and cognitive disabilities during childhood: the EPIPAGE cohort study
    Stephane Marret
    Department of Neonatal Medicine, Rouen University Hospital and Region INSERM Team, ERI 28, Neovasc, Institute for Biomedical Research and Innovation, Rouen University, Rouen, France
    PLoS ONE 8:e62683. 2013
    ..To investigate the association of motor and cognitive/learning deficiencies and overall disabilities in very preterm (VPT) children and their relations to gestational age (GA) and brain lesions...
  3. doi request reprint Pathophysiology of cerebral palsy
    Stephane Marret
    Department of Neonatal Medicine and Centre of Child Functional Education, Rouen University Hospital, Rouen, France INSERM Region Team ERI 28, Rouen Institute for Medical Research and Innovation, School of Medicine, Rouen University, Rouen, France Electronic address
    Handb Clin Neurol 111:169-76. 2013
    ..Only two strategies have succeeded in decreasing CP in 2-year-old children: hypothermia in full-term newborns with moderate neonatal encephalopathy and administration of magnesium sulfate to mothers in preterm labor...
  4. ncbi request reprint Fetal and neonatal cerebral infarcts
    S Marret
    Department of Neonatal Medicine, Clinique de Pédiatrie et de Puériculture, Hopital Charles Nicolle, Rouen, France
    Biol Neonate 79:236-40. 2001
    ..Treatment of seizures is nevertheless necessary, because it seems that they accelerate anoxia-induced neuronal death in animal models of focal hypoxic ischemia...
  5. ncbi request reprint Magnesium sulphate given before very-preterm birth to protect infant brain: the randomised controlled PREMAG trial*
    S Marret
    Department of Neonatal Medicine, Rouen University Hospital, Rouen, France
    BJOG 114:310-8. 2007
    ..To evaluate whether magnesium sulphate (MgSO(4)) given to women at risk of very-preterm birth would be neuroprotective in preterm newborns and would prevent neonatal mortality and severe white-matter injury (WMI)...
  6. ncbi request reprint Neonatal and 5-year outcomes after birth at 30-34 weeks of gestation
    Stephane Marret
    Department of Neonatal Medicine, Rouen University Hospital and Inserm Avenir Research Group, Institute for Biomedical Research, University of Rouen, Rouen, France
    Obstet Gynecol 110:72-80. 2007
    ..To evaluate the rates of in-hospital death, neonatal complications, and 5-year outcomes of infants born at 30-34 weeks of gestation...
  7. doi request reprint [Effect of magnesium sulphate on mortality and neurologic morbidity of the very-preterm newborn (of less than 33 weeks) with two-year neurological outcome: results of the prospective PREMAG trial]
    S Marret
    Service de pédiatrie néonatale et réanimation, hôpital universitaire de Rouen, 1 rue de Germont, Rouen Cedex, France
    Gynecol Obstet Fertil 36:278-88. 2008
    ..To evaluate whether magnesium sulphate (MgSO(4)) given to women at risk of very-preterm birth would be neuroprotective in preterm newborns...
  8. ncbi request reprint [Effects of maternal smoking during pregnancy on fetal brain development]
    S Marret
    Service de pédiatrie néonatale et réanimation, Hopital Charles Nicolle, CHU de Rouen, 76031 Rouen Cedex
    J Gynecol Obstet Biol Reprod (Paris) 34:3S230-3. 2005
    ..Nicotine was the best studied component of tobacco in animal studies. It was show that it interferes directly by stimulation of neurotransmitters or indirectly by inducing brain hypoxia...
  9. ncbi request reprint [Brain plasticity in preterm infant]
    S Marret
    Service de pédiatrie néonatale et réanimation, Hopital Charles Nicolle, CHU de Rouen, 76031 Rouen Cedex, France
    Arch Pediatr 14:519-21. 2007
  10. ncbi request reprint [Indications for early intervention in the prevention and management of neurodevelopmental disorders]
    S Marret
    Service de pédiatrie néonatale et réanimation, Hopital Charles Nicolle, CHU de Rouen, 76031 Rouen Cedex, France
    Arch Pediatr 11:611-3. 2004
  11. doi request reprint [Is it possible to protect the preterm infant brain and to decrease later neurodevelopmental disabilities?]
    S Marret
    Service de pédiatrie néonatale et réanimation, hôpital universitaire de Rouen, F 76031 cedex France
    Arch Pediatr 15:S31-41. 2008
    ..Due to their specific properties, a careful evaluation of aspirin, anaesthetic drugs and tocolytics should be done in the next months...
  12. doi request reprint [Specific care of very-preterm children with neurodisabilities: results of EPIPAGE study]
    S Marret
    Service de Pédiatrie néonatale et réanimation Centre d Education fonctionnelle de l Enfant, hôpital universitaire de Rouen, F 76000 Rouen
    Arch Pediatr 15:595-7. 2008
  13. ncbi request reprint [Special outpatient services at 5 and 8 years in very-preterm children in the EPIPAGE study]
    S Marret
    Service de pédiatrie néonatale et réanimation, Centre d Education fonctionnelle de l Enfant, hôpital universitaire de Rouen, Universite de Rouen, Rouen, France
    Arch Pediatr 16:S17-27. 2009
    ..Such studies are few and were done only in extremely low-birthweight or extremely preterm newborns in the United States...
  14. doi request reprint Prenatal low-dose aspirin and neurobehavioral outcomes of children born very preterm
    Stephane Marret
    Department of Neonatal Medicine, Rouen University Hospital, Rouen, France
    Pediatrics 125:e29-34. 2010
    ..Low-dose aspirin (LDA) given during pregnancy may alter brain development in very preterm infants. We report the short- and long-term outcomes of very preterm infants according to LDA treatment...
  15. doi request reprint [Prevention of cerebral palsy using magnesium sulfate in pre-term newborns]
    S Marret
    Service de pédiatrie néonatale et réanimation, Centre d Education fonctionnelle de l Enfant, Hopital Charles Nicolle, CHU de Rouen, 1, rue de Germont, 76031 Rouen Cedex, France
    Arch Pediatr 18:324-30. 2011
    ....
  16. ncbi request reprint Effect of acamprosate on neonatal excitotoxic cortical lesions in in utero alcohol-exposed hamsters
    Christine Adde-Michel
    UPRES EA 2122, Faculty of Medicine and Pharmacy, Rouen University, 22 Boulevard Gambetta, F 76183 Rouen, France
    Neurosci Lett 374:109-12. 2005
    ..A significant dose-related effect of acamprosate was observed. In addition, acamprosate rescued 27% of the pups injected with 10 microg ibotenic acid, a lethal dose in alcohol-exposed animals...
  17. ncbi request reprint Effect of perinatal alcohol exposure on ibotenic acid-induced excitotoxic cortical lesions in newborn hamsters
    Christine Adde-Michel
    UPRES EA 2122, School of Medicine and Pharmacy, Rouen University, Rouen, France
    Pediatr Res 57:287-93. 2005
    ..This study shows that alcohol exposure at levels that do not induce neuron migration disorders is sufficient to enhance the effects of the hypoxia-ischemia mimicking effects of ibotenic acid...
  18. doi request reprint Prenatal alcohol exposure affects vasculature development in the neonatal brain
    Sylvie Jegou
    Region INSERM Team, ERI28, Laboratory of Microvascular Endothelium and Neonate Brain Lesions, IRIB, Normandy University, Rouen, France
    Ann Neurol 72:952-60. 2012
    ..Although recent studies suggest that alcohol can affect angiogenesis in adults, the impact of prenatal alcohol exposure on brain microvasculature remains poorly understood...
  19. ncbi request reprint Age-dependent neonatal intracerebral hemorrhage in plasminogen activator inhibitor 1 knockout mice
    Philippe Leroux
    From the Laboratory of Microvascular Endothelium and Neonate Brain Lesions PL, PLO, ND, BJG, CB L, IL N, SM, INSERM Région Haute Normandie Team ERI 28, Institute for Research and Innovation in Biomedicine and Laboratory of Psychology and Neuroscience of Cognition and Affects VR, PSY NCA, University of Rouen, Rouen Department of Biochemistry CB L, IBC and Department of Neonatal Pediatrics and Intensive Care SM, Rouen University Hospital, Rouen, France and Laboratory of Angiogenesis and Neurovascular Link PC, Vesalius Research Center, VIB and Laboratory of Angiogenesis and Neurovascular Link PC, Department of Oncology, KU Leuven, Belgium
    J Neuropathol Exp Neurol 73:387-402. 2014
    ..Neonatal PAI-1 mice could be a useful ICH/IVH model for studying the ontogenic window of vascular immaturity and vascular protection against later neurodisabilities. ..
  20. ncbi request reprint The efficiency of glutamate uptake differs between neonatal and adult cortical microvascular endothelial cells
    Maryline Lecointre
    ERI28 NeoVasc, Laboratory of Microvascular Endothelium and Neonate Brain Lesions, Normandy University, Institute for Research and Innovation in Biomedicine, Rouen, France
    J Cereb Blood Flow Metab 34:764-7. 2014
    ....
  21. ncbi request reprint Role of tissue-derived plasminogen activator (t-PA) in an excitotoxic mouse model of neonatal white matter lesions
    Olivier Hennebert
    MERCI, UPRES EA 2122, Faculty of Medicine and Pharmacy, Rouen University, Rouen, France
    J Neuropathol Exp Neurol 63:53-63. 2004
    ..Inactivation of t-PA might confer protection by prolonged hemostasis. The role of t-PA in cyst expansion suggests a new approach to the development of neuroprotective strategies in infants with developing WM lesions...
  22. ncbi request reprint The antiapoptotic effect of remifentanil on the immature mouse brain: an ex vivo study
    Fabien Tourrel
    From the Laboratory of Microvascular Endothelium and Neonate Brain Lesions, Rouen Institute for Biomedical Research IRIB, University of Rouen, Cedex, France Laboratory of Pharmaceutical Organic Chemistry, ULB, Brussels, Belgium Departments of Pharmacology, and Anesthetics and Intensive Care, Rouen University Hospital, Rouen, France
    Anesth Analg 118:1041-51. 2014
    ..P. remifentanil), on the immature brain...
  23. pmc Hypoxia-ischemia or excitotoxin-induced tissue plasminogen activator- dependent gelatinase activation in mice neonate brain microvessels
    Priscilla L Omouendze
    Haute Normandie INSERM ERI 28, Institute for Research and Innovation in Biomedicine of Rouen University, Rouen, France
    PLoS ONE 8:e71263. 2013
    ..Both MMP-2 and MMP-9 activities appeared t-PA-dependent. The data suggest that vascular directed protease inhibition may have neuroprotection potential against neonatal brain injuries...
  24. doi request reprint High t-PA release by neonate brain microvascular endothelial cells under glutamate exposure affects neuronal fate
    Vincent Jean Henry
    Region INSERM Team, ERI28 NeoVasc, Laboratory of Microvascular Endothelium and Neonate Brain Lesions, University of Rouen, Institute for Research and Innovation in Biomedicine, Rouen, France
    Neurobiol Dis 50:201-8. 2013
    ..The data point out putative implication of microvessels in glutamate neurotoxicity in the development, and justify research towards vessel oriented neuroprotection strategies in neonates...
  25. ncbi request reprint Glucocorticoid treatment in an ischaemic-like excitotoxic model of periventricular leucomalacia in mice
    Cyrille Arquié
    Laboratory of Micro Environnement et Renouvellement Cellulaire Integre, UPRES EA2122, University of Rouen, France
    BJOG 109:989-96. 2002
    ..To determine the effects of fluorinated glucocorticoids on the occurrence and extent of ischaemic-like excitotoxic grey and white matter cerebral injuries in an animal model...
  26. ncbi request reprint [Preventive vaccination strategy during the perinatal period]
    Didier Pinquier
    Pédiatrie néonatale et réanimation, pôle Femme Mère Enfant CHU Rouen, Institut hospitalo universitaire, Universite de Rouen, 76031 Rouen Cedex
    Rev Prat 60:1363-7. 2010
    ..The arrival of the newborn will be the opportunity to update vaccinations of the whole family particularly according chicken pox, measles, rubella, whooping cough and flu vaccines...
  27. ncbi request reprint Detection of Neisseria meningitidis DNA from skin lesion biopsy using real-time PCR: usefulness in the aetiological diagnosis of purpura fulminans
    Pierre Staquet
    Service de pédiatrie néonatale et réanimation, Centre Hospitalier Universitaire de Rouen, 1, rue de Germont, 76031, Rouen Cedex, France
    Intensive Care Med 33:1168-72. 2007
    ..The present study evaluated the usefulness of a real-time polymerase chain reaction (rtPCR) assay for the detection of Neisseria meningitidis (Nm) and genogrouping on skin lesion biopsies in patients with purpura fulminans (PF)...
  28. ncbi request reprint Neonatal hypoxic preconditioning involves vascular endothelial growth factor
    Vincent Laudenbach
    Institut National de la Sante et de la Recherche Medicale, AVENIR Research Group, IFRMP23, University of Rouen, Department of Neonatal Pediatrics and Intensive Care, Rouen University Hospital, France
    Neurobiol Dis 26:243-52. 2007
    ..Thus, exogenous as well as endogenous VEGF reduces excitotoxic brain lesions in the developing mouse. The VEGF/VEGFR2/Flk1 pathway is involved in the neuroprotective response to HxP...
  29. ncbi request reprint [Cerebral infarction in full-term newborns: MR imaging features]
    M Brasseur-Daudruy
    Service de Radiologie Pediatrique, CHU de Rouen, 1, rue de Germont, 76031 Rouen Cedex
    J Radiol 89:1085-93. 2008
    ..Perinatal stroke is the most frequent cause of congenital hemiplegia. The MR imaging features of cerebral infarction in full-term newborns will be reviewed and the underlying etiologies discussed...
  30. ncbi request reprint [Breastfeeding and Cytomegalovirus infection in preterm infants. How to reduce the risks?]
    S Radi
    Service de pédiatrie néonatale et réanimation, Hopital Charles Nicolle, 1, rue de Germont, 76000 Rouen, France
    Arch Pediatr 14:31-5. 2007
    ..This may reduce the risk of postnatal vertical virus transmission with minimal logistical difficulties and without interrupting breastfeeding...
  31. ncbi request reprint [Who is it necessary to vaccine against whooping-cough?]
    D Pinquier
    Service de pédiatrie néonatale et réanimation, Hopital Charles Nicolle, CHU de Rouen, 1, rue de Germont, 76031 Rouen, France
    Gynecol Obstet Fertil 35:1064-8. 2007
    ....
  32. ncbi request reprint Intracerebral inflammatory pseudotumour in a 16-month-old boy
    S Radi-Bencteux
    Department of Neonatalogy and Intensive Care, Rouen University Hospital, Rouen, France
    Neuropediatrics 34:330-3. 2003
    ..Our case is the first described in an infant younger than four years of age. This observation suggests that chronic evolution may start earlier than thought in adult cases, perhaps due to an autoimmune process...
  33. ncbi request reprint [Early spontaneous ileal perforations in preterm infants: report of 4 cases]
    M Arsac
    Service de pédiatrie néonatale et réanimation, Hopital Charles Nicolle, 1, rue de Germont, 76031 Rouen Cedex, France
    Arch Pediatr 12:1613-6. 2005
    ..Ileal perforation in the absence of signs of necrotizing enterocolitis is rarely reported but should be well known because of its good prognosis...
  34. ncbi request reprint [Management of meconium peritonitis: a remarkable case of idiopathic meconium peritonitis diagnosed antenatally]
    F Sergent
    Clinique Gynécologique et Obstétricale, Pavillon Mère Enfant, Hopital Charles Nicolle, 76031 Rouen Cedex
    J Gynecol Obstet Biol Reprod (Paris) 32:575-81. 2003
    ..Prognosis remains good after antenatal diagnosis for neonates free of cystic fibrosis, providing delivery takes place in a center with adequate technical facilities...
  35. doi request reprint [Evaluation of language at 6 years in children born prematurely without cerebral palsy: prospective study of 55 children]
    A Charollais
    Service de pédiatrie néonatale et réanimation, Centre d Education fonctionnelle de l Enfant, centre de référence pour troubles des apprentissages, hôpital universitaire de Rouen, 1, rue de Germont, 76000 Rouen, France
    Arch Pediatr 17:1433-9. 2010
    ..Very premature birth carries a high risk of neurocognitive disabilities and learning disorders. Acquiring sufficient speech skills is crucial to good school performance...
  36. doi request reprint [Vaccine prevention in perinatal health care: parents, children and professionals]
    D Pinquier
    Service de pédiatrie néonatale et réanimation, pôle Mère Enfant, Hopital Charles Nicolle, CHU Rouen, 1, rue de Germont, 76031 Rouen, France
    Gynecol Obstet Fertil 36:461-8. 2008
    ..Midwives and nurses occupy a central place in family policy and become, with obstetricians-gynecologists and pediatricians, key actors for the effectiveness and the success of vaccine strategies in perinatal health...
  37. doi request reprint [Vaccination rate of premature infants at 6 and 24 months of age: a pilot study]
    D Pinquier
    EA4309, Service de pédiatrie néonatale et réanimation, Universite de Rouen, CHU Charles Nicolle, Institut hospitalo universitaire de recherche biomédicale, 1 rue Germont, 76031 Rouen Cedex, France
    Arch Pediatr 16:1533-9. 2009
    ..There are few data examining the vaccine practices for 0- to 24-month-old premature infants born before 33 GW. The aim of the study was to examine the vaccine coverage in this population according to the French schedule at 6 and 24 months...
  38. ncbi request reprint [Neonatal management of a child exposed to tobacco in utero and postnatal biomarkers]
    A Diguet
    Clinique Gynécologique et Obstétricale
    J Gynecol Obstet Biol Reprod (Paris) 34:3S458-69. 2005
    ..However, the maternal curve can be studied and measurement of the exhaled carbon monoxide in late pregnancy is a valid reflection of neonatal impregnation...
  39. doi request reprint Anaesthesia mode for caesarean section and mortality in very preterm infants: an epidemiologic study in the EPIPAGE cohort
    V Laudenbach
    Department of Neonatology and Pediatric Intensive Care, Rouen Institute for Biomedical Research, University of Rouen, Rouen, France
    Int J Obstet Anesth 18:142-9. 2009
    ..Little is known about the influence of anaesthesia for caesarean section on outcome in very preterm infants...
  40. doi request reprint Vascular-endothelial growth factor and its high affinity receptor VEGFR-2 in the normal versus destructive lesions human forebrain during development: an immuno-histochemical comparative study
    Loïc Sentilhes
    EA 4309 Neovasc, Rouen Institute for Medical Research and Innovation, School of Medicine, University of Rouen, Normandy, France
    Brain Res 1385:77-86. 2011
    ..These data suggest that VEGF plays specific roles and may not be mediated by VEGFR-2 in human forebrain structures exposed to ischemia...
  41. doi request reprint Compared outcomes of very preterm infants born in 2000 and 2005
    Anne Marie Guerrot
    Department of Neonatal Medicine, Rouen University Hospital and EA Neovasc, Institute of Biomedical Research and Innovation, School of Medicine, Rouen University, France
    Acta Paediatr 101:731-5. 2012
    ..To compare neonatal and 2-year outcomes in very premature infants born 5 years apart...
  42. doi request reprint NO-dependent protective effect of VEGF against excitotoxicity on layer VI of the developing cerebral cortex
    Faiza El Ghazi
    EA NeoVasc 4309, Laboratory of Microvascular Endothelium and Neonate Brain Lesions, Rouen Institute for Biomedical Research, European Institute for Peptide Research IFR 23, University of Rouen, Rouen, France
    Neurobiol Dis 45:871-86. 2012
    ..Contrasting with mature brain, NO production induced by high concentrations of glutamate is neuroprotective and is required for the anti-necrotic effect of VEGF(A)...
  43. doi request reprint Neuroprotective effects vary across nonsteroidal antiinflammatory drugs in a mouse model of developing excitotoxic brain injury
    P Leroux
    Institute for Biomedical Research, Rouen University, Charles Nicolle University Hospital, Rouen, France
    Neuroscience 167:716-23. 2010
    ..In conclusion, perinatal NSAID administration may have beneficial effects on brain injury if appropriately timed...
  44. ncbi request reprint Isolated mild fetal cerebral ventriculomegaly: a retrospective analysis of 26 cases
    A Mercier
    Department of Neonatology, Rouen University Hospital Charles Nicolle, Rouen, France
    Prenat Diagn 21:589-95. 2001
    ..If ventriculomegaly is persistent, prenatal management should be carried out to investigate chromosomal abnormalities, viral infection, and fetal cerebral parenchymal damage. A long postnatal clinical follow-up is required...
  45. doi request reprint Neurodevelopmental outcome in prenatally diagnosed isolated agenesis of the corpus callosum
    A Chadie
    Institut National de la Sante et de la Recherche Medicale, AVENIR Research Group and Department of Neonatal Medicine and Intensive Care, Rouen Institute for Biomedical Research, University of Rouen, F 76183 Rouen, France
    Acta Paediatr 97:420-4. 2008
    ..To evaluate long-term neurodevelopmental outcomes in children with prenatally diagnosed, isolated agenesis of the corpus callosum (ACC)...
  46. doi request reprint Influence of gestational age on fibrinolysis from birth to postnatal day 10
    Loïc Sentilhes
    Department of Obstetrics and Gynecology, Rouen Institute for Medical Research and Innovation, Rouen, France
    J Pediatr 158:377-382.e1. 2011
    ..To compare components of the fibrinolytic cascade in newborns of gestational age ranging from extreme prematurity to full term, at birth and for the next 10 days, and in their mothers at delivery...
  47. doi request reprint Newborn- and adult-derived brain microvascular endothelial cells show age-related differences in phenotype and glutamate-evoked protease release
    Hélène Legros
    EA 4309 Neovasc Microvascular Endothelium and Neonatal Brain Lesions, IHURBM, IFRMP 23, School of Medicine and Pharmacy, University of Rouen, Rouen, France
    J Cereb Blood Flow Metab 29:1146-58. 2009
    ..The glutamate-mediated release of t-PA, MMP-2, and MMP-9 proteolytic activities in neonatal BMECs was blocked by MK-801. Conceivably, this protease release from neonatal BMECs may participate in neonatal brain lesions...
  48. doi request reprint [Palivizumab immunoprophylaxis: use in clinical practice, safety and beneficial effects in France]
    D Pinquier
    Service de pédiatrie néonatale et réanimation, Institut hospitalo universitaire de recherche biomédicale, EA 4309, CHU Charles Nicolle, Universite de Rouen, 1 rue Germont, Rouen, France
    Arch Pediatr 16:1443-52. 2009
    ..Infants treated have been followed for one year in order to assess conditions of use of palivizumab, safety, tolerability, and its impact on respiratory syncytial virus (RSV) hospitalisation rate...
  49. doi request reprint [Perinatal management and neurological outcome of newborns hospitalized with Rhesus hemolytic disease]
    P Gobalakichenane
    Service de pédiatrie néonatale et réanimation, CHU de Rouen, 1, rue de Germont, 76031 Rouen Cedex, France
    Gynecol Obstet Fertil 36:984-90. 2008
    ..To evaluate perinatal management and neurological outcome in a group of infants born with Rhesus fetomaternal allo-immunization...
  50. ncbi request reprint [Physiopathology of periventricular leukomalacia]
    S Marret
    Service de pédiatrie néonatale et réanimation, C H U de Rouen, Hopital Charles Nicolle, France
    Rev Med Brux 24:416-9. 2003
    ..When the overwhelming glutamatergic signal has been triggered, neuroprotective agents turning off the excitotoxic cascade, including calcium blockers, growth factors and others, are promising therapeutic tools...
  51. ncbi request reprint [Congenital hypothyroidism: adult outcome]
    C Lecointre
    Service de Neonatologie, Hopital Charles Nicolle, 1, rue de Germont, 76031 Rouen Cedex, France
    Arch Pediatr 14:1119-22. 2007
  52. ncbi request reprint Effect of enteral supplementation with glutamine on mesenteric blood flow in premature neonates
    A Mercier
    Department of Neonatology, Rouen University Hospital Charles Nicolle, Rouen, France
    Clin Nutr 22:133-7. 2003
    ..This study investigated the effects of enterally supplied glutamine on mesenteric blood flow in premature neonate...