Philippe Ducrotte

Summary

Affiliation: Rouen University Hospital
Country: France

Publications

  1. doi request reprint [Gastroparesis: pathophysiology and management]
    Philippe Ducrotte
    Faculte de Medecine et de Pharmacie, ADEN EA 4311 hôpital Charles Nicolle, Département d hépatogastroentérologie et de nutrition, Rouen Cedex, France
    Presse Med 41:721-9. 2012
  2. pmc Clinical trial: Lactobacillus plantarum 299v (DSM 9843) improves symptoms of irritable bowel syndrome
    Philippe Ducrotte
    Department of Gastroenterology Inserm UMR 1073, Rouen University Hospital and Rouen University, 76031 Rouen Cedex, France
    World J Gastroenterol 18:4012-8. 2012
  3. ncbi request reprint Octreotide in refractory functional epigastric pain with nutritional impairment--an open study
    P Ducrotte
    Digestive Tract Research Group, Rouen University Hospital, Rouen, France
    Aliment Pharmacol Ther 13:969-75. 1999
  4. doi request reprint [Irritable bowel syndrome: dietary and pharmacological therapeutic options]
    P Ducrotte
    ADEN EA 4311 IFRMP 23, Département d Hépato Gastroentérologie et de Nutrition, CHRU, Hopital Charles Nicolle, 1, rue de Germont, 76031 Rouen Cedex, France
    Gastroenterol Clin Biol 33:S68-78. 2009
  5. ncbi request reprint How do people with gastro-oesophageal reflux disease perceive their disease? Results of a multinational survey
    Philippe Ducrotte
    Rouen University Hospital, Rouen, France
    Curr Med Res Opin 23:2857-65. 2007
  6. ncbi request reprint Symptomatic efficacy of beidellitic montmorillonite in irritable bowel syndrome: a randomized, controlled trial
    P Ducrotte
    Digestive Tract Research Group EA 3234 IFRMP23, Rouen University Hospital, France
    Aliment Pharmacol Ther 21:435-44. 2005
  7. doi request reprint [Microbiota and irritable bowel syndrome]
    P Ducrotte
    ADEN EA 4311 IFRMP 23, Department of Hepatogastroenterology and Nutrition, Regional University Hospital, Charles Nicolle Hospital, 1 rue de Germont, Rouen Cedex, France
    Gastroenterol Clin Biol 34:S52-6. 2010
  8. doi request reprint [Irritable bowel syndrome: from the gut to the brain-gut]
    P Ducrotte
    ADEN EA 4311 IFRMP 23, Département d hépatogastroentérologie et de nutrition, Hopital Charles Nicolle, 76031 Rouen Cedex, France
    Gastroenterol Clin Biol 33:703-12. 2009
  9. ncbi request reprint [Abdominal bloating: an up-to-date]
    P Ducrotte
    Département d hépatogastroentérologie et de nutrition, CHU de Rouen, 1 rue de Germont, Rouen Cedex, France
    Gastroenterol Clin Biol 33:F94-100. 2009
  10. ncbi request reprint ReQuest: a new questionnaire for the simultaneous evaluation of symptoms and well-being in patients with gastro-oesophageal reflux
    Philippe Ducrotte
    Département d Hépato Gastroentérologie et de Nutrition, Hopital Charles Nicolle, Rouen, France
    Digestion 75:79-86. 2007

Collaborators

Detail Information

Publications69

  1. doi request reprint [Gastroparesis: pathophysiology and management]
    Philippe Ducrotte
    Faculte de Medecine et de Pharmacie, ADEN EA 4311 hôpital Charles Nicolle, Département d hépatogastroentérologie et de nutrition, Rouen Cedex, France
    Presse Med 41:721-9. 2012
    ....
  2. pmc Clinical trial: Lactobacillus plantarum 299v (DSM 9843) improves symptoms of irritable bowel syndrome
    Philippe Ducrotte
    Department of Gastroenterology Inserm UMR 1073, Rouen University Hospital and Rouen University, 76031 Rouen Cedex, France
    World J Gastroenterol 18:4012-8. 2012
    ..To assess the symptomatic efficacy of Lactobacillus plantarum 299v (L. plantarum 299v) (DSM 9843) for the relief of abdominal symptoms in a large subset of irritable bowel syndrome (IBS) patients fulfilling the Rome III criteria...
  3. ncbi request reprint Octreotide in refractory functional epigastric pain with nutritional impairment--an open study
    P Ducrotte
    Digestive Tract Research Group, Rouen University Hospital, Rouen, France
    Aliment Pharmacol Ther 13:969-75. 1999
    ..To test the therapeutic efficacy of octreotide administered subcutaneously for the relief of chronic refractory epigastric pain severe enough to provoke nutritional impairment...
  4. doi request reprint [Irritable bowel syndrome: dietary and pharmacological therapeutic options]
    P Ducrotte
    ADEN EA 4311 IFRMP 23, Département d Hépato Gastroentérologie et de Nutrition, CHRU, Hopital Charles Nicolle, 1, rue de Germont, 76031 Rouen Cedex, France
    Gastroenterol Clin Biol 33:S68-78. 2009
    ..A non pharmacological therapeutic approach has to be considered, particularly in patients with severe symptoms, in combination with pharmacological treatment...
  5. ncbi request reprint How do people with gastro-oesophageal reflux disease perceive their disease? Results of a multinational survey
    Philippe Ducrotte
    Rouen University Hospital, Rouen, France
    Curr Med Res Opin 23:2857-65. 2007
    ..To determine how patients with gastro-oesophageal reflux disease (GERD) perceive their condition...
  6. ncbi request reprint Symptomatic efficacy of beidellitic montmorillonite in irritable bowel syndrome: a randomized, controlled trial
    P Ducrotte
    Digestive Tract Research Group EA 3234 IFRMP23, Rouen University Hospital, France
    Aliment Pharmacol Ther 21:435-44. 2005
    ..Beidellitic montmorillonite is a purified clay containing a double aluminium and magnesium silicate...
  7. doi request reprint [Microbiota and irritable bowel syndrome]
    P Ducrotte
    ADEN EA 4311 IFRMP 23, Department of Hepatogastroenterology and Nutrition, Regional University Hospital, Charles Nicolle Hospital, 1 rue de Germont, Rouen Cedex, France
    Gastroenterol Clin Biol 34:S52-6. 2010
    ..All these arguments for a deleterious role of the gut microbiota lead to the actual discuss to consider new therapeutic options, including mainly pre- and probiotics and maybe antibiotics...
  8. doi request reprint [Irritable bowel syndrome: from the gut to the brain-gut]
    P Ducrotte
    ADEN EA 4311 IFRMP 23, Département d hépatogastroentérologie et de nutrition, Hopital Charles Nicolle, 76031 Rouen Cedex, France
    Gastroenterol Clin Biol 33:703-12. 2009
    ..This knowledge is crucial because of the need for updated treatment strategies and new pharmacological and/or cognitive or behavioral therapies...
  9. ncbi request reprint [Abdominal bloating: an up-to-date]
    P Ducrotte
    Département d hépatogastroentérologie et de nutrition, CHU de Rouen, 1 rue de Germont, Rouen Cedex, France
    Gastroenterol Clin Biol 33:F94-100. 2009
    ..Probiotics are another promising option. In some centers, a non pharmacological therapeutic approach, mainly based on hypnosis, is discussed...
  10. ncbi request reprint ReQuest: a new questionnaire for the simultaneous evaluation of symptoms and well-being in patients with gastro-oesophageal reflux
    Philippe Ducrotte
    Département d Hépato Gastroentérologie et de Nutrition, Hopital Charles Nicolle, Rouen, France
    Digestion 75:79-86. 2007
    ..Both versions, the long and the short, have identical metrological qualities...
  11. ncbi request reprint [Irritable bowel syndrome]
    Philippe Ducrotte
    Département d hépato gastroentérologie et de nutrition CHRU, hôpital Charles Nicolle 76031 Rouen
    Rev Prat 53:773-9. 2003
  12. ncbi request reprint The role of remote gut inflammation in duodenojejunal dysmotility
    I Le Blanc-Louvry
    Digestive Tract Research Group EA 3234 IFRMP 23, Rouen University Hospital, Rouen, France
    Neurogastroenterol Motil 14:143-50. 2002
    ....
  13. ncbi request reprint [Extra-esophageal manifestations of gastroesophageal reflux disease in adults]
    Philippe Ducrotte
    Groupe de recherche sur l appareil digestif, l environnement et la nutrition ADEN, Département d Hépato Gastroentérologie et de Nutrition, Hopital Charles Nicolle, 76031 Rouen Cedex, France
    Rev Prat 58:1421-3, 1426-8. 2008
    ..In case of adequate response, treatment can be tapered down to determine the minimal required maintenance dose. Anti-reflux surgery could be an alternative in some cases...
  14. ncbi request reprint [Abdominal pain: the gastroenterologist's point of view]
    Philippe Ducrotte
    Groupe Appareil Digestif, Environnement, Nutrition EA 3234 IFRMP23, Département d Hépato Gastroentérologie et de Nutrition, Hopital Charles Nicolle, 76031 Rouen Cedex
    Gastroenterol Clin Biol 27:S68-72. 2003
  15. ncbi request reprint Enteral glutamine stimulates protein synthesis and decreases ubiquitin mRNA level in human gut mucosa
    Moise Coeffier
    Appareil Digestif, Environnement et Nutrition, Institut Fédératif de Recherche Multidisciplinaire sur les Peptides, centre d investigation clinique, Rouen, France
    Am J Physiol Gastrointest Liver Physiol 285:G266-73. 2003
    ..Enteral glutamine stimulates mucosal protein synthesis and may attenuate ubiquitin-dependent proteolysis and thus improve protein balance in human gut...
  16. doi request reprint Increased proteasome-mediated degradation of occludin in irritable bowel syndrome
    Moise Coeffier
    Nutrition Unit, Rouen University Hospital, Rouen, France
    Am J Gastroenterol 105:1181-8. 2010
    ..Thus, we aimed to evaluate proteasome composition and activities in colonic mucosa of IBS patients and its putative pathogenic role...
  17. ncbi request reprint Effects of intragastric L-arginine administration on proximal stomach tone under basal conditions and after an intragastric diet
    Guillaume Savoye
    ADEN EA 3234, Department of Gastroenterology and Nutrition, Rouen University, Hospital C Nicolle, 1 rue de Germont, 76031, Rouen Cedex, France
    Dig Dis Sci 51:2147-53. 2006
    ..This 15-g dosage was as well tolerated as the placebo and was associated with no significant changes in gastric emptying patterns...
  18. ncbi request reprint Combined enteral infusion of glutamine, carbohydrates, and antioxidants modulates gut protein metabolism in humans
    Moise Coeffier
    Appareil Digestif Environnement Nutrition EA4311, The Institute for Biomedical Research, the European Institute for Peptide Research, and Clinical Investigation Center 0204, Rouen University and Rouen University Hospital, Rouen, France
    Am J Clin Nutr 88:1284-90. 2008
    ..Available data suggest that nutrients can affect intestinal protein metabolism, which contributes to the regulation of gut barrier function...
  19. doi request reprint The expression and the cellular distribution of the tight junction proteins are altered in irritable bowel syndrome patients with differences according to the disease subtype
    Nathalie Bertiaux-Vandaële
    Department of Gastroenterology, Rouen University Hospital, France
    Am J Gastroenterol 106:2165-73. 2011
    ..The objective of this study was to study zonula occludens-1 (ZO-1), occludin, and claudin-1 in the colonic mucosa of patients with IBS...
  20. pmc Role of toll like receptors in irritable bowel syndrome: differential mucosal immune activation according to the disease subtype
    Liliana Belmonte
    INSERM Unit U1073, Rouen University, Rouen, France Institute for Research and Innovation in Biomedicine, Rouen University, Rouen, France Laboratory ofImmunology, IIHEMA, Consejo Nacional de Investigaciones Cientı ficas y Te cnicas, Academy National of Medicine, Buenos Aires, Argentine
    PLoS ONE 7:e42777. 2012
    ..However, the understanding of the precise molecular pathophysiology remains largely unknown...
  21. doi request reprint Long term efficacy of gastric electrical stimulation in intractable nausea and vomiting
    Guillaume Gourcerol
    Department of Physiology and INSERM UMR 1073 IRIB, Rouen University Hospital, University of Rouen, France
    Dig Liver Dis 44:563-8. 2012
    ....
  22. ncbi request reprint Effects of ondansetron on gastric tone and motility changes induced by a prolonged intraduodenal infusion of nutrients. Results of a placebo-controlled study
    Guillaume Savoye
    ADEN EA 3234, Department of Gastroenterology and Nutrition, Rouen University Hospital C Nicolle, 1 rue de Germont, 76031, Rouen, France
    Dig Dis Sci 52:2676-83. 2007
    ..This inhibitory effect was rapidly reversible. Ondansetron induced only minor motility changes in the antrum and had no effect on fundic relaxation promoted by IDI...
  23. doi request reprint Nonoperable patients with superficial esophageal cancer treated by photodynamic therapy after chemoradiotherapy have more severe complications than patients treated in primary intent
    Stephane Lecleire
    Department of Hepato Gastroenterology and Nutrition and Appareil Digestif et Nutrition Equipe d Accueil 3234, Rouen University Hospital, Rouen, France
    Am J Gastroenterol 103:2215-9. 2008
    ..Photodynamic therapy (PDT) is a therapeutic option in patients with a superficial esophageal cancer. Recently, PDT was shown to be effective as a salvage therapy for a local recurrence after chemoradiotherapy (CRT)...
  24. ncbi request reprint Acute enteral glutamine infusion enhances heme oxygenase-1 expression in human duodenal mucosa
    Moise Coeffier
    Appareil Digestif, Environnement et Nutrition ADEN, EA 3234 and Institut Fédératif de Recherches Multidisciplinaires sur les peptides, Faculte de Medecine Pharmacie, Service d Anatomie Pathologique, Hopital Charles Nicolle, Rouen, France
    J Nutr 132:2570-3. 2002
    ..51, P = 0.030). In conclusion, glutamine enhanced HO-1 mRNA and protein expression in human duodenal mucosa. These data support further evaluation of the effects of glutamine on intestinal HO-1 during states of intestinal inflammation...
  25. doi request reprint Gastric electrical stimulation increases the discomfort threshold to gastric distension
    Guillaume Gourcerol
    Nutrition, Gut and Brain Unit, INSERM UMR 1073, Institute for Biomedical Research and Innovation, Rouen University, Rouen, France
    Eur J Gastroenterol Hepatol 25:213-7. 2013
    ..Gastric electrical stimulation (GES) is now considered as a new therapeutic alternative for patients with medically refractory vomiting and/or nausea, although its mechanisms of action remain poorly understood...
  26. ncbi request reprint Gastric tone variations during gastric infusion of fiber-supplemented formulas
    Guillaume Savoye
    The Digestive Tract Research Group, Rouen University Hospital, France
    J Gastroenterol Hepatol 20:409-14. 2005
    ..The objective of this study was to assess variations of fundic tone and their relation to antroduodenal motility before, during and after nasogastric feeding supplemented or not with fibers...
  27. doi request reprint Combined glutamine and arginine decrease proinflammatory cytokine production by biopsies from Crohn's patients in association with changes in nuclear factor-kappaB and p38 mitogen-activated protein kinase pathways
    Stephane Lecleire
    Appareil Digestif Environnement Nutrition EA4311, Institute for Biomedical Research, IFRMP23, Rouen University and Rouen University Hospital, Rouen, France
    J Nutr 138:2481-6. 2008
    ..These results could be the basis of prospective studies evaluating the effects of enteral supply of combined Arg and Gln during active CD...
  28. ncbi request reprint Factors that affect gastric passage of video capsule
    Emmanuel Ben-Soussan
    Service d Hepatogastroenterologie, Centre Hospitalier Universitaire Ch Nicolle, Rouen, France
    Gastrointest Endosc 62:785-90. 2005
    ..We retrospectively studied gastric transit time, gastric retention, and completeness of capsule endoscopy (CE) in relation to the conditions in which it was performed...
  29. pmc Transient neonatal Cryptosporidium parvum infection triggers long-term jejunal hypersensitivity to distension in immunocompetent rats
    Rachel Marion
    Laboratoire de Parasitologie and ADEN UPRES EA 3234, CHU Charles Nicolle, 1, rue de Germont, 76031 Rouen, France
    Infect Immun 74:4387-9. 2006
    ..001) but not myeloperoxidase levels (P > 0.05). Data warrant further evaluation of the role of early cryptosporidiosis in the development of chronic inflammatory gut conditions...
  30. ncbi request reprint Diagnostic yield and therapeutic implications of capsule endoscopy in obscure gastrointestinal bleeding
    Emmanuel Ben Soussan
    Département d hépatogastroentérologie et de nutrition, Groupe de Recherche sur l Appareil Digestif EA 3234, Hôpital C Nicolle, 1 rue de Germont, 76031 Rouen Cedex
    Gastroenterol Clin Biol 28:1068-73. 2004
    ..In addition, we evaluated the software of automatic detection of red zones (SBI, Given Imaging)...
  31. doi request reprint Delayed gastric emptying determined using the 13C-octanoic acid breath test in patients with systemic sclerosis
    Isabelle Marie
    Department of Internal Medicine, Rouen University Hospital, Rouen, France
    Arthritis Rheum 64:2346-55. 2012
    ....
  32. ncbi request reprint Baseline nutritional status is predictive of response to treatment and survival in patients treated by definitive chemoradiotherapy for a locally advanced esophageal cancer
    Frederic Di Fiore
    Digestive Oncology Unit, Gastroenterology Department, Rouen University Hospital, Rouen, France
    Am J Gastroenterol 102:2557-63. 2007
    ..To assess the impact of baseline nutritional status on treatment response and survival in nonmetastatic patients with a locally advanced esophageal cancer (LAEC) treated with definitive chemoradiotherapy (CRT)...
  33. ncbi request reprint Lack of effect of acute enteral arginine infusion on whole-body and intestinal protein metabolism in humans
    Sophie Claeyssens
    Appareil Digestif, Environnement et Nutrition ADEN EA 3234, Institut Fédératif de Recherche Multidisciplinaire sur les Peptides, and CIC INSERM CHU, Rouen, France
    Dig Dis Sci 52:1826-32. 2007
    ..Whether arginine might specifically affect these parameters in catabolic or inflammatory situations remains to be determined...
  34. ncbi request reprint Modulation of nitric oxide and cytokines production by L-arginine in human gut mucosa
    Stephane Lecleire
    Appareil Digestif Environnement Nutrition ADEN EA 3234 and Institut Fédératif de Recherches Multidisciplinaires sur les peptides IFR n 23, CIC Inserm CHU, 76031 Rouen Cedex, France
    Clin Nutr 24:353-9. 2005
    ..Arginine is a conditionally essential amino-acid with immuno-modulatory properties, mainly through the nitric oxide (NO) pathway...
  35. ncbi request reprint Glutamine and CXC chemokines IL-8, Mig, IP-10 and I-TAC in human intestinal epithelial cells
    Rachel Marion
    Appareil Digestif Environnement Nutrition ADEN EA 3234, Institut Fédératif de Recherches Multidisciplinaires sur les Peptides I F R 23, Rouen, France
    Clin Nutr 23:579-85. 2004
    ..Human intestinal epithelial cells act as a sentinel in the immune response and produce CXC chemokines such as IL-8, Mig, IP-10 and I-TAC. Glutamine has various effects on immuno-inflammatory response in human intestine...
  36. ncbi request reprint Acute esophageal necrosis: a 1-year prospective study
    Emmanuel Ben Soussan
    Digestive Tract Research Group and Department of Pathology, Rouen University Hospital, Rouen Cedex, France
    Gastrointest Endosc 56:213-7. 2002
    ..A prospective 1-year study was conducted to assess the frequency, clinical spectrum, histologic description, and follow-up of acute esophageal necrosis unrelated to ingestion of caustic or corrosive agents...
  37. ncbi request reprint An impaired accommodation of the proximal stomach to a meal is associated with symptoms after distal gastrectomy
    Isabelle Le Blanc-Louvry
    Digestive Tract Research Group, Appareil Digestif Environnement Nutrition ADEN EA 3234 IFRMP 23, Rouen University Hospital, Rouen, France
    Am J Gastroenterol 98:2642-7. 2003
    ..The aim of this study was to assess gastric emptying and postprandial proximal gastric tone variations depending on the presence of postoperative symptoms after Billroth II gastrectomy (BII)...
  38. ncbi request reprint Glutamine pretreatment reduces IL-8 production in human intestinal epithelial cells by limiting IkappaBalpha ubiquitination
    Aurélie Hubert-Buron
    Appareil Digestif Environnement et Nutrition ADEN EA 3234, Institut Federatif de Recherches Multidisciplinaires sur les Peptides, Medical Faculty, Rouen, France
    J Nutr 136:1461-5. 2006
    ..This study indicates that glutamine pretreatment may reduce the intestinal inflammatory response by limiting the proteolysis of IkappaBalpha...
  39. doi request reprint Are digestive symptoms in women presenting with pelvic endometriosis specific to lesion localizations? A preliminary prospective study
    Horace Roman
    Department of Gynecology and Obstetrics, Rouen University Hospital, Rouen, France
    Hum Reprod 27:3440-9. 2012
    ..What are the types and frequency of digestive symptoms in patients with different localizations of pelvic endometriosis and which specific symptoms are related to rectal stenosis?..
  40. ncbi request reprint Multidetector CT in patients with esophageal stent as a palliative treatment for stenosing esophageal cancer: a feasibility study
    Véronique Maneglia
    QUANT IF EA4051, LITIS Radiology Department, Rouen University Hospital Charles Nicolle, Rouen, France
    Scand J Gastroenterol 42:1339-46. 2007
    ..The aim of this study was to determine the feasibility of MDCT follow-up of esophageal SEMS and to describe the imaging patterns encountered as well as correlating them with fibroscopic evaluation...
  41. ncbi request reprint Gastric electrical stimulation in intractable nausea and vomiting: assessment of predictive factors of favorable outcomes
    Guillaume Gourcerol
    Department of Physiology, Digestive Tract Research Group ADEN EA 4311 and European Institute for Peptide Research IFRMP23, Rouen University Hospital, University of Rouen, 1 rue de Germont, 76031 Rouen Cedex, France
    J Am Coll Surg 209:215-21. 2009
    ..We aimed to determine preoperative factors associated with positive response during GES. Thirty-three consecutive patients received implants for medically refractory nausea or vomiting or both...
  42. ncbi request reprint Concomitant variations of gastric tone and duodenal motility in humans: results of a placebo-controlled study assessing octreotide and sumatriptan
    Guillaume Savoye
    Groupe Appareil Digestif Environnement Nutrition, Rouen University Hospital, France
    Scand J Gastroenterol 41:536-43. 2006
    ..To describe the concomitant effects of octreotide and sumatriptan on fundic tone and duodenal phase III activity...
  43. ncbi request reprint Effects of glutamine supplementation on gut barrier, glutathione content and acute phase response in malnourished rats during inflammatory shock
    Liliana Belmonte
    ADEN EA3234, Institut Hospitalo Universitaire de Recherche Biomédicale and Institut Fédératif de Recherches Multidisciplinaires sur les Peptides, Rouen, France
    World J Gastroenterol 13:2833-40. 2007
    ..To evaluate the effect of glutamine on intestinal mucosa integrity, glutathione stores and acute phase response in protein-depleted rats during an inflammatory shock...
  44. ncbi request reprint Gastric electrical stimulation in medically refractory nausea and vomiting
    Guillaume Gourcerol
    Department of Physiology, Rouen University Hospital, Rouen, France
    Eur J Gastroenterol Hepatol 19:29-35. 2007
    ....
  45. doi request reprint Rumination syndrome: when the lower oesophageal sphincter rises
    Guillaume Gourcerol
    Physiology Department and ADEN EA4311 Research Group, Institute for Biomedical Research, European Institute for Peptide Research IFRMP 23, Rouen University Hospital, Rouen, France
    Dig Liver Dis 43:571-4. 2011
    ..However, the precise mechanisms preventing reflux at the gastro-oesophageal junction during the rise in intra-gastric pressure remains unknown...
  46. pmc Cryptosporidium parvum isolate-dependent postinfectious jejunal hypersensitivity and mast cell accumulation in an immunocompetent rat model
    Samira Khaldi
    Parasitology Laboratory, Rouen University Hospital, and Institute for Biomedical Research, University of Rouen, Rouen, France
    Infect Immun 77:5163-9. 2009
    ..This cryptosporidiosis rat model is a relevant model for the study of underlying mechanisms of postinfectious IBS-like symptoms...
  47. doi request reprint Bleeding gastric vascular ectasia treated by argon plasma coagulation: a comparison between patients with and without cirrhosis
    Stephane Lecleire
    Department of Hepato Gastroenterology and Nutrition, Endoscopy Unit, ADEN EA3234 IFRMP23 Research Group, Rouen University Hospital Charles Nicolle, Rouen, France
    Gastrointest Endosc 67:219-25. 2008
    ..Gastric vascular ectasia (GVE) is an uncommon etiology of GI bleeding. GVE can affect not only patients with cirrhosis but also patients with a variety of chronic diseases...
  48. ncbi request reprint Lack of correlation between morbid obesity and severe gastroesophageal reflux disease in candidates for bariatric surgery: results of a large prospective study
    Alberto Zalar
    Gastroenterology Department UMR 1073, Rouen University Hospital, 1 rue de Germont, 76000, Rouen, France
    Obes Surg 23:1939-41. 2013
    ..Moreover, no relationship was found between GERD and not only BMI but also abdominal diameter. ..
  49. ncbi request reprint Delayed postprandial fundic relaxation: a new abnormal finding in functional dyspepsia
    Guillaume Savoye
    Digestive Tract Research Group, Rouen University Hospital Charles Nicolle, France
    Scand J Gastroenterol 40:354-5. 2005
  50. ncbi request reprint Colonic transit time and MR colonography
    Celine Savoye-Collet
    Department of Radiology, Quantif, Rouen University Hospital Charles Nicolle, 1 rue de Germont, F 76031 Rouen, France
    AJR Am J Roentgenol 179:435-6. 2002
  51. ncbi request reprint [Lower gastrointestinal bleeding due to ileal lipoma. Diagnosis contribution of contrast enhanced helical CT]
    Guillaume Gourcerol
    Département d Hépato Gastroentérologie, Hopital Charles Nicolle, 76031 Rouen Cedex
    Gastroenterol Clin Biol 28:185-7. 2004
    ..The patient was taking aspirin at admission. A bleeding intussuscepted ileal lipoma was localized with a contrast enhanced helical computed tomography. This diagnosis was confirmed by laparotomy...
  52. ncbi request reprint Effects of enteral feeding on antroduodenal motility in healthy volunteers with 2 different fiber-supplemented diets: a 24-hour manometric study
    Mickael Bouin
    Digestive Tract Research Group, Rouen University Hospital Charles Nicolle, Rouen, France
    JPEN J Parenter Enteral Nutr 28:169-75. 2004
    ..The aim of the study was to evaluate antroduodenal motor activity during intermittent intragastric feeding and between enteral solutions supplemented with new recommended soluble or standard insoluble fibers...
  53. ncbi request reprint Palliative esophageal stent placement using endoscopic guidance without fluoroscopy
    Emmanuel Ben Soussan
    Digestive Tract Research Group, Rouen University Hospital Charles Nicolle, 76031 Rouen Cedex
    Gastroenterol Clin Biol 29:785-8. 2005
    ..We assessed safety and effectiveness of expandable esophageal metal stent placement under endoscopic control without fluoroscopy using a thin gastroscope...
  54. ncbi request reprint Duodenal intraepithelial T lymphocytes in patients with functional dyspepsia
    Gilles Gargala
    Parasitology Department, Rouen University Hospital, France
    World J Gastroenterol 13:2333-8. 2007
    ....
  55. pmc Gastric electrical stimulation decreases gastric distension-induced central nociception response through direct action on primary afferents
    Wassila Ouelaa
    Nutrition, Gut and Brain Unit ADEN INSERM U1073, Institute for Biomedical Research and Innovation, Rouen University, Rouen, France
    PLoS ONE 7:e47849. 2012
    ..Gastric electrical stimulation (GES) is an effective therapy to treat patients with chronic dyspepsia refractory to medical management. However, its mechanisms of action remain poorly understood...
  56. pmc Gastric stimulation: influence of electrical parameters on gastric emptying in control and diabetic rats
    Isabelle Le Blanc-Louvry
    Digestive Tract Research Group, Rouen University Hospital, Rouen, France
    BMC Surg 2:5. 2002
    ..The aim of this study was to test the effect of different pulse frequencies and amplitudes during gastric stimulation (GS) on gastric emptying in the rat...
  57. doi request reprint Small intestinal bacterial overgrowth in systemic sclerosis
    Isabelle Marie
    Department of Internal Medicine, Rouen University Hospital, 76301 Rouen Cedex, France
    Rheumatology (Oxford) 48:1314-9. 2009
    ....
  58. ncbi request reprint Pseudo-angiocholitis revealing adult-onset Still's disease
    Isabelle Marie
    Department of Internal Medicine, Centre Hospitalier Universitaire de Rouen Boisguillaume, 76031 Rouen, France
    Dig Dis Sci 49:627-8. 2004
  59. ncbi request reprint Acute hepatitis due to buprenorphine administration
    Sophie Herve
    Digestive Tract Research Group ADEN EA3234 IFRMP23, Rouen University Hospital, France
    Eur J Gastroenterol Hepatol 16:1033-7. 2004
    ..Hepatotoxicity is poorly documented, since only few cases of hepatic injury have been reported...
  60. doi request reprint Factors associated with diagnosis of obscure gastrointestinal bleeding by video capsule enteroscopy
    Lucie Lepileur
    Gastroenterology Department, Digestive Endoscopy Unit, Rouen University Hospital and Institut National de la Sante et de la recherche Medicale U 1073, University of Rouen, Rouen, France
    Clin Gastroenterol Hepatol 10:1376-80. 2012
    ..However, little is known about the factors associated with a diagnosis of OGIB by CE...
  61. ncbi request reprint [Mallory-Weiss syndrome: diagnosis and treatment]
    Stephane Lecleire
    Unité D Endoscopie Digestive, Département d hépato gastroentérologie et nutrition, Rouen Cedex, France
    Presse Med 39:640-4. 2010
    ..The use of proton pump inhibitors and antiemetics seems logical in all cases, although nothing in the literature demonstrates their efficacy...
  62. ncbi request reprint Is a 2-liter PEG preparation useful before capsule endoscopy?
    Emmanuel Ben-Soussan
    Rouen University Hospital Ch Nicolle, Rouen, France
    J Clin Gastroenterol 39:381-4. 2005
    ....
  63. ncbi request reprint [Management of functional dyspepsia]
    Philippe Ducrotte
    Hépato Gastroentérologie et Nutrition, ADEN EA 3234 IFRMP 23, Hopital Charles Nicolle, Rouen
    Gastroenterol Clin Biol 30:408-14. 2006
  64. ncbi request reprint Does mechanical massage of the abdominal wall after colectomy reduce postoperative pain and shorten the duration of ileus? Results of a randomized study
    Isabelle Le Blanc-Louvry
    Digestive Tract Research Group, Rouen University Hospital Charles Nicolle, Rouen, France
    J Gastrointest Surg 6:43-9. 2002
    ..8 +/- 0.3 days vs. 3.6 +/- 0.4 days, P < 0.01). No adverse effects were observed. These results suggest that mechanical massage of the abdominal wall may decrease postoperative pain and ileus after colectomy...
  65. doi request reprint Autoantibodies against appetite-regulating peptide hormones and neuropeptides: putative modulation by gut microflora
    Serguei O Fetissov
    Digestive System and Nutrition Laboratory ADEN EA3234, Institute of Biomedical Research, Rouen University and Hospital, IFRMP23, Rouen, France
    Nutrition 24:348-59. 2008
    ....
  66. ncbi request reprint [Irritable bowel syndrome: current treatment options]
    Philippe Ducrotte
    Département d hépatogastroentérologie et de nutrition, Centre Hospitalier, ADEN EA 3234 IFRMP 23, Rouen
    Presse Med 36:1619-26. 2007
    ..Non-drug options such as hypnosis, psychotherapy, relaxation, or yoga, may also be proposed to some patients. Probiotics are a possible treatment in the future...
  67. doi request reprint The Bowel Function Index: a new validated scale for assessing opioid-induced constipation
    Philippe Ducrotte
    HepatoGastroEnterology Department CHU, Rouen, France
    Curr Med Res Opin 28:457-66. 2012
    ..As the discomfort associated with OIC can lead to poor compliance with the opioid treatment, a shift in focus towards patient assessment is often advocated...
  68. ncbi request reprint Glutamine decreases interleukin-8 and interleukin-6 but not nitric oxide and prostaglandins e(2) production by human gut in-vitro
    Moise Coeffier
    Appareil Digestif Environnement et Nutrition ADEN EA 3234, Rouen, France
    Cytokine 18:92-7. 2002
    ..Glutamine modulates cytokine production in various tissues but its effects on the production of other inflammatory mediators such as eicosanoids and nitric oxide have not been investigated in human gut...
  69. ncbi request reprint [Assessment of the quality and psychological impact of information delivered using official consent forms in digestive endoscopy]
    Isabelle Roque
    Groupe de recherche sur l appareil digestif, Hopital Charles Nicolle, Rouen
    Gastroenterol Clin Biol 27:17-21. 2003
    ..To test the impact of information brochures and informed consent forms in patients undergoing digestive endoscopy procedures...