Nathalie Rouach

Summary

Country: France

Publications

  1. pmc Astroglial gap junctions shape neuronal network activity
    Ulrike Pannasch
    Neuroglial Interactions in Cerebral Physiopathology Center for Interdisciplinary Research in Biology Collège de France CNRS UMR7241 INSERM U1050 Paris, France
    Commun Integr Biol 5:248-54. 2012
  2. pmc Astroglial networking contributes to neurometabolic coupling
    Carole Escartin
    CEA DSV I2BM MIRCen and CNRS URA2210, Fontenay aux Roses Paris, France
    Front Neuroenergetics 5:4. 2013
  3. pmc Astroglial potassium clearance contributes to short-term plasticity of synaptically evoked currents at the tripartite synapse
    Jérémie Sibille
    N Rouach Neuroglial Interactions in Cerebral Physiopathology, Collège de France, CIRB, CNRS UMR 7241, INSERM U1050, 11, place Marcelin Berthelot, 75005 Paris, France
    J Physiol 592:87-102. 2014
  4. ncbi request reprint Astroglial metabolic networks sustain hippocampal synaptic transmission
    Nathalie Rouach
    Inserm U840, College de France, 11 place Marcelin Berthelot, 75005 Paris, France
    Science 322:1551-5. 2008
  5. pmc Astroglial networks scale synaptic activity and plasticity
    Ulrike Pannasch
    Centre National de la Recherche Scientifique Unité Mixte de Recherche 7241 Institut National de la Santé et de la Recherche Médicale U1050, College de France, 75005 Paris, France
    Proc Natl Acad Sci U S A 108:8467-72. 2011
  6. ncbi request reprint Connexin 30 sets synaptic strength by controlling astroglial synapse invasion
    Ulrike Pannasch
    1 Center for Interdisciplinary Research in Biology, College de France, INSERM U1050, CNRS UMR 7241, Labex Memolife, PSL Research University, Paris, France 2 Doctoral school N 158, Pierre and Marie Curie University, Paris, France 3
    Nat Neurosci 17:549-58. 2014
  7. ncbi request reprint Neurons and brain macrophages regulate connexin expression in cultured astrocytes
    Annette Koulakoff
    INSERM U114, College de France, Paris, France
    Cell Commun Adhes 10:407-11. 2003
  8. ncbi request reprint Neurons set the tone of gap junctional communication in astrocytic networks
    Nathalie Rouach
    INSERM U114, College de France, 11 place Marcelin Berthelot, 75005 Paris, France
    Neurochem Int 45:265-72. 2004
  9. ncbi request reprint S1P inhibits gap junctions in astrocytes: involvement of G and Rho GTPase/ROCK
    Nathalie Rouach
    INSERM U587, College de France, 11, place Marcelin Berthelot, 75005 Paris, France
    Eur J Neurosci 23:1453-64. 2006
  10. ncbi request reprint Emerging role for astroglial networks in information processing: from synapse to behavior
    Ulrike Pannasch
    Neuroglial Interactions in Cerebral Physiopathology, Center for Interdisciplinary Research in Biology, Centre Nationale de la Recherche Scientifique CNRS Unité Mixte de Recherche 7241, Institut National de la Santé et de la Recherche Médicale INSERM Unité 1050, College de France, 75005 Paris, France
    Trends Neurosci 36:405-17. 2013

Collaborators

Detail Information

Publications16

  1. pmc Astroglial gap junctions shape neuronal network activity
    Ulrike Pannasch
    Neuroglial Interactions in Cerebral Physiopathology Center for Interdisciplinary Research in Biology Collège de France CNRS UMR7241 INSERM U1050 Paris, France
    Commun Integr Biol 5:248-54. 2012
    ..Here we show that astroglial gap junctional communication also regulates neuronal network activity. We discuss these findings and their implications for brain information processing...
  2. pmc Astroglial networking contributes to neurometabolic coupling
    Carole Escartin
    CEA DSV I2BM MIRCen and CNRS URA2210, Fontenay aux Roses Paris, France
    Front Neuroenergetics 5:4. 2013
    ....
  3. pmc Astroglial potassium clearance contributes to short-term plasticity of synaptically evoked currents at the tripartite synapse
    Jérémie Sibille
    N Rouach Neuroglial Interactions in Cerebral Physiopathology, Collège de France, CIRB, CNRS UMR 7241, INSERM U1050, 11, place Marcelin Berthelot, 75005 Paris, France
    J Physiol 592:87-102. 2014
    ..These results show that astrocytes integrate synaptic activity via multiple ionic channels and transporters and contribute to short-term plasticity in part via potassium clearance mediated by Kir4.1 channels...
  4. ncbi request reprint Astroglial metabolic networks sustain hippocampal synaptic transmission
    Nathalie Rouach
    Inserm U840, College de France, 11 place Marcelin Berthelot, 75005 Paris, France
    Science 322:1551-5. 2008
    ..These results indicate that astroglial gap junctions provide an activity-dependent intercellular pathway for the delivery of energetic metabolites from blood vessels to distal neurons...
  5. pmc Astroglial networks scale synaptic activity and plasticity
    Ulrike Pannasch
    Centre National de la Recherche Scientifique Unité Mixte de Recherche 7241 Institut National de la Santé et de la Recherche Médicale U1050, College de France, 75005 Paris, France
    Proc Natl Acad Sci U S A 108:8467-72. 2011
    ..Altogether, these results establish connexins as critical proteins for extracellular homeostasis, important for the formation of functional synapses...
  6. ncbi request reprint Connexin 30 sets synaptic strength by controlling astroglial synapse invasion
    Ulrike Pannasch
    1 Center for Interdisciplinary Research in Biology, College de France, INSERM U1050, CNRS UMR 7241, Labex Memolife, PSL Research University, Paris, France 2 Doctoral school N 158, Pierre and Marie Curie University, Paris, France 3
    Nat Neurosci 17:549-58. 2014
    ..Taken together, these results establish connexin 30 as a critical regulator of synaptic strength by controlling the synaptic location of astroglial processes. ..
  7. ncbi request reprint Neurons and brain macrophages regulate connexin expression in cultured astrocytes
    Annette Koulakoff
    INSERM U114, College de France, Paris, France
    Cell Commun Adhes 10:407-11. 2003
    ..Thus, in brain diseases and injuries, neuronal death associated with the BM activation may decrease GJC in astrocytes and therefore have a physiopathological relevance...
  8. ncbi request reprint Neurons set the tone of gap junctional communication in astrocytic networks
    Nathalie Rouach
    INSERM U114, College de France, 11 place Marcelin Berthelot, 75005 Paris, France
    Neurochem Int 45:265-72. 2004
    ....
  9. ncbi request reprint S1P inhibits gap junctions in astrocytes: involvement of G and Rho GTPase/ROCK
    Nathalie Rouach
    INSERM U587, College de France, 11, place Marcelin Berthelot, 75005 Paris, France
    Eur J Neurosci 23:1453-64. 2006
    ..This novel effect of S1P may have an important physiopathological significance when considering the proposed roles for astrocyte gap junctions on neuronal survival...
  10. ncbi request reprint Emerging role for astroglial networks in information processing: from synapse to behavior
    Ulrike Pannasch
    Neuroglial Interactions in Cerebral Physiopathology, Center for Interdisciplinary Research in Biology, Centre Nationale de la Recherche Scientifique CNRS Unité Mixte de Recherche 7241, Institut National de la Santé et de la Recherche Médicale INSERM Unité 1050, College de France, 75005 Paris, France
    Trends Neurosci 36:405-17. 2013
    ..The present review critically discusses the impact of astroglial networks on normal and pathological neuronal information processing as well as the underlying mechanisms. ..
  11. ncbi request reprint Hydrogen peroxide increases gap junctional communication and induces astrocyte toxicity: regulation by brain macrophages
    Nathalie Rouach
    INSERM U114, College de France, Paris, France
    Glia 45:28-38. 2004
    ..Finally, when astrocytes are cocultured with brain macrophages, the effects of H2O2 on both GJC and toxicity are not observed, revealing a new protective role of brain macrophages during oxidative stress...
  12. ncbi request reprint Astroglial networks: a step further in neuroglial and gliovascular interactions
    Christian Giaume
    Inserm U840, College de France, 75005 Paris, France
    Nat Rev Neurosci 11:87-99. 2010
    ..This intercellular communication between glia has implications for neuroglial and gliovascular interactions and hence has added another level of complexity to our understanding of brain function...
  13. ncbi request reprint Astroglial connexin 43 sustains glutamatergic synaptic efficacy
    Oana Chever
    Neuroglial Interactions in Cerebral Physiopathology, Center for Interdisciplinary Research in Biology, College de France, Centre National de la Recherche Scientifique UMR 7241, Institut National de la Santé et de la Recherche Médicale U1050, Labex Memolife, PSL Research University, 75005 Paris, France
    Philos Trans R Soc Lond B Biol Sci 369:20130596. 2014
    ..These results reveal connexin 43 as a critical player in neuroglial interactions by supporting synaptic efficacy. ..
  14. ncbi request reprint Zinc-induced inhibition of protein synthesis and reduction of connexin-43 expression and intercellular communication in mouse cortical astrocytes
    Mehrdad Alirezaei
    INSERM U11, College de France, 11, place Marcelin Berthelot, 75231 Paris Cedex 05, France
    Eur J Neurosci 16:1037-44. 2002
    ..The resulting decrease in the intercellular communication between astrocytes should alter the function of surrounding neurons as well as their survival...
  15. ncbi request reprint Astroglial connexin43 hemichannels tune basal excitatory synaptic transmission
    Oana Chever
    Neuroglial Interactions in Cerebral Physiopathology, Center for Interdisciplinary Research in Biology, Collège de France, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 7241, Institut National de la Santé et de la Recherche Médicale U1050, 75005 Paris, France
    J Neurosci 34:11228-32. 2014
    ..These data reveal Cx43 hemichannels as a novel astroglial release pathway at play in basal conditions, which tunes the moment-to-moment glutamatergic synaptic transmission. ..