L Rostaing

Summary

Country: France

Publications

  1. ncbi request reprint mTOR inhibitor/proliferation signal inhibitors: entering or leaving the field?
    Lionel Rostaing
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse
    J Nephrol 23:133-42. 2010
  2. doi request reprint Review article: use of induction therapy in liver transplantation
    Lionel Rostaing
    Nephrology, Dialysis and Organ Transplantation Service, CHU Rangueil, Toulouse, France
    Transplant Rev (Orlando) 26:246-60. 2012
  3. doi request reprint Conversion to tacrolimus once-daily from ciclosporin in stable kidney transplant recipients: a multicenter study
    Lionel Rostaing
    Hopital de Rangueil, Nephrology, Dialysis and Organ Transplant Unit, Toulouse, France
    Transpl Int 25:391-400. 2012
  4. pmc Kinetics of plasmatic cytokines and cystatin C during and after hemodialysis in septic shock-related acute renal failure
    Nicolas Mayeur
    Anesthesia and Intensive Care Unit Department, GRCB 48, Purpan University Hospital, Place du Dr Baylac, TSA 40031, 31059 Toulouse Cedex 9, France
    Crit Care 14:R115. 2010
  5. pmc A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma
    Andreas A Schnitzbauer
    University Hospital Regensburg, Department of Surgery, Regensburg, Germany
    BMC Cancer 10:190. 2010
  6. pmc Belatacept-versus cyclosporine-based immunosuppression in renal transplant recipients with pre-existing diabetes
    Lionel Rostaing
    Department of Nephrology, Dialysis and Multiorgan Transplantation, University Hospital, Toulouse, France
    Clin J Am Soc Nephrol 6:2696-704. 2011
  7. ncbi request reprint Viral infections after kidney transplantation
    L Rostaing
    Unit of Nephrology, Dialysis and Organ Translplantation, CHU Rangueil, Toulouse, France
    Minerva Urol Nefrol 63:59-71. 2011
  8. doi request reprint Treatment of symptomatic transplant glomerulopathy with rituximab
    Lionel Rostaing
    Department of Nephrology, Dialysis and Multiorgan Transplantation, Toulouse University Hospital, CHU Rangueil, Toulouse Cedex, France
    Transpl Int 22:906-13. 2009
  9. ncbi request reprint Lack of effect of chronic hepatitis C virus infection on T-cell cytokine production in chronic hemodialysis patients
    L Rostaing
    Nephrology, Hemodialysis and Multiorgan Transplant Unit, Toulouse University Hospital, Toulouse, France
    Am J Nephrol 21:194-9. 2001
  10. pmc Switching from calcineurin inhibitor-based regimens to a belatacept-based regimen in renal transplant recipients: a randomized phase II study
    Lionel Rostaing
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, TSA 50032, 31059 Toulouse Cedex 9, France
    Clin J Am Soc Nephrol 6:430-9. 2011

Detail Information

Publications137 found, 100 shown here

  1. ncbi request reprint mTOR inhibitor/proliferation signal inhibitors: entering or leaving the field?
    Lionel Rostaing
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse
    J Nephrol 23:133-42. 2010
    ..Its blockade, by mTOR inhibitors (mTOR-Is), such as sirolimus or everolimus, leads to antiproliferative effects...
  2. doi request reprint Review article: use of induction therapy in liver transplantation
    Lionel Rostaing
    Nephrology, Dialysis and Organ Transplantation Service, CHU Rangueil, Toulouse, France
    Transplant Rev (Orlando) 26:246-60. 2012
    ..Wider use of induction in liver transplantation is now merited, using individualized strategies to support reduced CNI exposure or steroid-free immunosuppression...
  3. doi request reprint Conversion to tacrolimus once-daily from ciclosporin in stable kidney transplant recipients: a multicenter study
    Lionel Rostaing
    Hopital de Rangueil, Nephrology, Dialysis and Organ Transplant Unit, Toulouse, France
    Transpl Int 25:391-400. 2012
    ..The effect of conversion on cardiovascular parameters was not clinically meaningful, however, marked improvement in ciclosporin-related cosmetic side effects was observed. (ClinicalTrials.gov number: NCT00481481)...
  4. pmc Kinetics of plasmatic cytokines and cystatin C during and after hemodialysis in septic shock-related acute renal failure
    Nicolas Mayeur
    Anesthesia and Intensive Care Unit Department, GRCB 48, Purpan University Hospital, Place du Dr Baylac, TSA 40031, 31059 Toulouse Cedex 9, France
    Crit Care 14:R115. 2010
    ..In this study, we described p cytokines and cystatin C variations during and after hemodialysis in septic-shock patients with acute kidney injury (AKI)...
  5. pmc A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma
    Andreas A Schnitzbauer
    University Hospital Regensburg, Department of Surgery, Regensburg, Germany
    BMC Cancer 10:190. 2010
    ..Therefore, we designed a prospective RCT to determine if the mTOR inhibitor sirolimus can improve hepatocellular carcinoma (HCC)-free patient survival in liver transplant (LT) recipients with a pre-transplant diagnosis of HCC...
  6. pmc Belatacept-versus cyclosporine-based immunosuppression in renal transplant recipients with pre-existing diabetes
    Lionel Rostaing
    Department of Nephrology, Dialysis and Multiorgan Transplantation, University Hospital, Toulouse, France
    Clin J Am Soc Nephrol 6:2696-704. 2011
    ..To assess the effect of belatacept in this high-risk group, we evaluated outcomes of the subpopulation with PD from previously published BENEFIT and BENEFIT-EXT trials...
  7. ncbi request reprint Viral infections after kidney transplantation
    L Rostaing
    Unit of Nephrology, Dialysis and Organ Translplantation, CHU Rangueil, Toulouse, France
    Minerva Urol Nefrol 63:59-71. 2011
    ..Thanks to modern laboratory technique, and a formidable antiviral armamentarium, viral infections in organ transplant patients i) can be easily detected at early stages, and ii) can be efficiently treated...
  8. doi request reprint Treatment of symptomatic transplant glomerulopathy with rituximab
    Lionel Rostaing
    Department of Nephrology, Dialysis and Multiorgan Transplantation, Toulouse University Hospital, CHU Rangueil, Toulouse Cedex, France
    Transpl Int 22:906-13. 2009
    ..5%) experienced severe infectious complications. We conclude that long-term RTx in kidney-transplant patients with TG is associated with allograft function/stabilization in 50% of cases...
  9. ncbi request reprint Lack of effect of chronic hepatitis C virus infection on T-cell cytokine production in chronic hemodialysis patients
    L Rostaing
    Nephrology, Hemodialysis and Multiorgan Transplant Unit, Toulouse University Hospital, Toulouse, France
    Am J Nephrol 21:194-9. 2001
    ..Conversely to HV, T lymphocytes from CHD patients are activated...
  10. pmc Switching from calcineurin inhibitor-based regimens to a belatacept-based regimen in renal transplant recipients: a randomized phase II study
    Lionel Rostaing
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, TSA 50032, 31059 Toulouse Cedex 9, France
    Clin J Am Soc Nephrol 6:430-9. 2011
    ..Belatacept-based regimens may provide a treatment option for patients who switch from CNI-based maintenance immunosuppression...
  11. doi request reprint Falsely elevated whole-blood tacrolimus concentrations in a kidney-transplant patient: potential hazards
    Lionel Rostaing
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Transpl Int 23:227-30. 2010
    ....
  12. ncbi request reprint Hepatitis C virus viral load after conversion from tacrolimus to cyclosporine in liver transplant patients: a pilot study
    J Guitard
    Department of Nephrology, Dialysis, and Multiorgan Transplant Unit, CHU Rangueil, 1 avenue Jean Poulhes, 31059 Toulouse, France
    Transplant Proc 39:2603-5. 2007
    ..We assessed whether conversion from tacrolimus (TAC) to cyclosporine (CsA) was associated with a reduction in hepatitis C virus (HCV) viral load among HCV-positive liver transplant (OLT) patients...
  13. ncbi request reprint Predictive factors for cytomegalovirus infection after orthotopic liver transplantation using an ultrasensitive polymerase chain reaction assay
    G Basse
    Multiorgan Transplant Unit, University Hospital, CHU Rangueil, Toulouse, France
    Transplant Proc 38:2339-41. 2006
    ..2), donor age >45 years (odds ratio = 11.4) and lymphocyte count at M2 <1300/mm(3) (odds ratio = 7.33). This study showed that the major factors associated with CMV infection were recipient CMV status, donor age, and lymphocyte count...
  14. doi request reprint T-cell function in maintenance renal transplant patients receiving mycophenolate mofetil and steroids with or without tacrolimus
    C Canivet
    Department of Nephrology, Toulouse, France
    Transplant Proc 40:3422-3. 2008
    ..As expected, intralymphocytic interleukin-2 (IL-2) and tumor necrosis factor-alpha (TNF-alpha) expressions were higher in patients not receiving CNIs...
  15. ncbi request reprint Predictive factors for anemia within the first year after orthotopic liver transplantation
    J Guitard
    Multiorgan Transplant Unit, University Hospital, CHU Rangueil, 1 avenue Jean Poulhes, TSA 50032, 31059 Toulouse Cedex 9, France
    Transplant Proc 38:2342-5. 2006
    ..We concluded that anemia was highly prevalent within the first year of post-OLT. This observation deserves further investigation and appropriate treatment...
  16. ncbi request reprint Tolerability of enteric-coated mycophenolate sodium to 1 year in combination with cyclosporine and corticosteroids in renal transplant recipients
    L Rostaing
    Department of Nephrology Transplantation, Hopital Rangueil, Toulouse, France
    Transplant Proc 38:2860-3. 2006
    ..Gastrointestinal adverse events were responsible for dose reduction or interruption in only 5% of patients...
  17. ncbi request reprint Monitoring HCMV infection with quantitative real-time PCR in HCMV-positive orthotopic liver transplant recipients, and predictive factors for treatment of the first episode of HCMV viremia
    A Pillet
    Multiorgan Transplant Unit, University Hospital, CHU Rangueil, 1 avenue Jean Poulhes, TSA 50032, 31059 Toulouse Cedex 9, France
    Transplant Proc 38:2335-8. 2006
    ..0443). The only factor that predicted treatment for the first episode of HCMV DNAemia was an alkaline phosphatase level >150 UI/mL at the time of the first HCMV reactivation [odds ratio 20 (1.96 to 203.3); P = .01]...
  18. doi request reprint JC virus DNA in the peripheral blood of renal transplant patients: a 1-year prospective follow-up in France
    C Mengelle
    Department of Virology, University Hospital, CH Toulouse, Cedex, France
    J Med Virol 83:132-6. 2011
    ..JCV replication must still be diagnosed and differentiated from BK virus infection because of its non-aggressive course...
  19. ncbi request reprint Acute renal failure following liver transplantation with induction therapy
    J Guitard
    Multiorgan Transplant Unit, University Hospital, Toulouse, France
    Clin Nephrol 65:103-12. 2006
    ..To identify the predictive factors for acute renal failure (ARF) in a retrospective study of 100 orthotopic liver transplantations (OLT) performed in 94 patients between 2000 and 2003...
  20. ncbi request reprint A monocentric observational study of darbepoetin alfa in anemic hepatitis-C-virus transplant patients treated with ribavirin
    Nassim Kamar
    Department of Nephrology, Toulouse University Hospital, France
    Exp Clin Transplant 6:271-5. 2008
    ..Darbepoetin alfa is used to treat renal anemia; however, little information is available concerning its use during the posttransplant period, especially in HCV-positive patients treated with ribavirin for active hepatitis C...
  21. ncbi request reprint A third renal transplantation: is it relevant and is it worth it?
    A H Reboux
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Rangueil, Toulouse, France
    Transplant Proc 37:4199-202. 2005
    ..Most patients were highly sensitized with 1 (0-4) HLA (classes I + II) incompatibility between donor and recipient...
  22. ncbi request reprint Prospective evaluation of BK virus DNAemia in renal transplant patients and their transplant outcome
    G Basse
    Department of Nephrology, Dialysis and Multiorgan Transplantation, Toulouse, France
    Transplant Proc 39:84-7. 2007
    ..After renal transplantation, the prevalence of BK virus (BKV) viruria, viremia, and nephritis (BKVAN) has been estimated at 30%, 13%, and 8%, respectively...
  23. ncbi request reprint Predicting factors of long-term results of OKT3 therapy for steroid resistant acute rejection following cadaveric renal transplantation
    L Rostaing
    Multi Organ Transplant Unit, Toulouse University Hospital, Toulouse, France
    Am J Nephrol 19:634-40. 1999
    ....
  24. ncbi request reprint Long-term results in renal transplant patients with allograft dysfunction after switching from calcineurin inhibitors to sirolimus
    Viorica Bumbea
    Multiorgan Transplant Unit, University Hospital, Toulouse, France
    Nephrol Dial Transplant 20:2517-23. 2005
    ..Switching from calcineurin inhibitors (CNIs) to sirolimus might improve renal function in chronic renal transplant patients...
  25. ncbi request reprint Long-term ribavirin therapy in hepatitis C virus-positive renal transplant patients: effects on renal function and liver histology
    Nassim Kamar
    Department of Nephrology, Dialysis, and Transplantation, CHU Rangueil, Toulouse, France
    Am J Kidney Dis 42:184-92. 2003
    ..The aims of this study were the evaluation of the efficacy and the safety of ribavirin monotherapy in 16 HCV-(+) RT patients (group A) matched to 32 HCV-(+) RT patients (group B) who did not receive ribavirin...
  26. doi request reprint FTY720 Inhibits Tumor Necrosis Factor-alpha-Induced Proliferation and Extracellular Signal-Regulated Kinase Phosphorylation of Human Smooth Muscle Cells
    T Bohler
    INSERM U858 I2MR EQ 10 Artériosclérose et Artériosclérose de Greffe, CHU Rangueil, Toulouse, France
    Transplant Proc 41:705-6. 2009
    ..We concluded that FTY720 may be a useful drug to inhibit chronic vascular rejection...
  27. ncbi request reprint Predictive factors of postrenal transplant anemia
    A Turkowski-Duhem
    Department of Nephrology and Transplantation, Hopital, Rangueil, Toulouse, France
    Transplant Proc 37:1009-11. 2005
    ..We included 99 renal transplants performed in our department in 2001, for whom the graft was still functioning at 1 year...
  28. ncbi request reprint Conversion from sirolimus to everolimus in maintenance renal transplant recipients within a calcineurin inhibitor-free regimen: results of a 6-month pilot study
    N Kamar
    Nephrology, Dialysis and Multi Organ Transplantation, CHU Rangueil, Toulouse Cedex 4, France
    Clin Nephrol 70:118-25. 2008
    ..To provide data on conversion of kidney transplant patients from sirolimus to everolimus...
  29. ncbi request reprint Relapse of membranous glomerulopathy after kidney transplantation: sustained remittance induced by rituximab
    H Weclawiak
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Rangueil, Toulouse, France
    Clin Nephrol 69:373-6. 2008
    ..Remission was observed before the third rituximab injection. After a follow-up of 42 months, the patient was still in remission, i.e., microalbuminuria of 107 mg/day...
  30. ncbi request reprint Rituximab therapy for acute humoral rejection after kidney transplantation
    Stanislas Faguer
    Department of Nephrology, Dialysis and Multiorgan Transplantation, University Hospital, CHU Rangueil, Toulouse, France
    Transplantation 83:1277-80. 2007
    ..At last follow-up, DSA had disappeared or decreased in four cases. Rituximab therapy, in addition to PE, might be of benefit for RT patients presenting with AHR...
  31. doi request reprint Alefacept combined with tacrolimus, mycophenolate mofetil and steroids in de novo kidney transplantation: a randomized controlled trial
    L Rostaing
    Toulouse University Hospital, Toulouse, France
    Am J Transplant 13:1724-33. 2013
    ..0%, p = 0.3). Patient and graft survival as well as renal function was similar between treatment groups. Safety and tolerability were generally similar between the treatment arms. Malignancy was higher in the alefacept treatment arm...
  32. ncbi request reprint Reversible posterior leukoencephalopathy syndrome in hepatitis C virus-positive long-term hemodialysis patients
    N Kamar
    Nephrology, Hemodialysis and Multiorgan Transplant Unit, Laboratory of Virology, and Department of Neuroradiology, Toulouse University Hospital, Toulouse, France
    Am J Kidney Dis 37:E29. 2001
    ....
  33. doi request reprint Disseminated herpes simplex type-2 (HSV-2) infection after solid-organ transplantation
    G Basse
    Department of Nephrology, Dialysis, and Multi Organ Transplantation, CHU, Rangueil, University Hospital, 1 av Jean Poulhes, TSA 50032, 31059, Toulouse Cedex 9, France
    Infection 36:62-4. 2008
    ..Although rare, HSV-2-disseminated infection, in the context of organ transplantation may be life-threatening, but can be cured if ACV therapy is initiated early in the course of this disease...
  34. ncbi request reprint Darbepoetin-alfa in renal-transplant patients: an observational monocentric study
    D Ribes
    Nephrology and Kidney Transplantation Department, CHU Rangueil, Toulouse University Hospital, France
    Clin Nephrol 69:102-6. 2008
    ..Although recombinant human erythropoietin (rHuEPO) is used in post-transplant anemic patients, little information is available concerning the use of darbepoetin-alfa (DA) in this population...
  35. ncbi request reprint Rituximab therapy for mixed cryoglobulinemia in seven renal transplant patients
    G Basse
    Multiorgan Transplant Unit, University Hospital, CHU Rangueil, 1 avenue Jean Poulhes, TSA 50032, 31059 Toulouse Cedex 9, France
    Transplant Proc 38:2308-10. 2006
    ..We concluded that rituximab therapy is effective in cryoglobulin-related renal dysfunction in renal transplant patients but, due to chronic immunosuppression, this may be achieved at the expense of infectious complications...
  36. ncbi request reprint Comparison of induction based on continuous vs discontinuous administration of antithymocyte globulins in renal transplant patients: efficacy and long-term safety
    L Esposito
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Rangueil Toulouse, France
    Transplant Proc 37:892-4. 2005
    ..This retrospective study sought to compare two modes of administration of antithymocyte globulin (RATG) after renal transplantation...
  37. ncbi request reprint Linezolid-induced interstitial nephritis in a kidney-transplant patient
    L Esposito
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Rangueil, Toulouse, France
    Clin Nephrol 68:327-9. 2007
    ..Because of the potential side effects of linezolid, i.e. myelosuppression and possibly nephrotoxicity, we recommend close monitoring of these parameters when linezolid therapy is attempted in kidney transplant patients...
  38. ncbi request reprint [Nephro-angiosclerosis in the graft: impact on graft survival. Study of 33 cases]
    P Bernadet-Monrozies
    , , CHU Rangueil, Toulouse
    Arch Mal Coeur Vaiss 88:1153-7. 1995
    ..In the context of early nephrosclerosis, the occurrence of acute rejection episode(s) is detrimental for the graft function...
  39. doi request reprint Rationale for using belatacept in combination with sirolimus
    H Weclawiak
    Department of Nephrology, Dialysis and Organ Transplantation, Toulouse University Hospital, Toulouse, France
    Transplant Proc 42:S29-31. 2010
    ..However, belatacept can potentially increase infections such as CMV. Thus, herein, we describe the rationale for combining belatacept with sirolimus for kidney transplant patients...
  40. doi request reprint Influenza A (H1N1) virus-induced hepatocellular injury in a kidney transplant patient
    M Daude
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Transpl Infect Dis 13:70-2. 2011
    ..The hepatocellular injury episode resolved after the patient had been placed on oseltamivir therapy. This observation suggests that acute hepatocellular injury could be linked to the influenza H1N1 virus...
  41. ncbi request reprint Assessment of glomerular and tubular functions in renal transplant patients receiving cyclosporine A in combination with either sirolimus or everolimus
    N Kamar
    Department of Nephrology, Dialysis and Transplantation, CHU Rangueil, Toulouse Cedex, France
    Clin Nephrol 63:80-6. 2005
    ....
  42. doi request reprint HLA class I antibodies provoke graft arteriosclerosis in human arteries transplanted into SCID/beige mice
    S Galvani
    INSERM U858 I2MR Team 10, IFR 31, CHU Rangueil, Toulouse, France
    Am J Transplant 9:2607-14. 2009
    ..Humoral alloreactivity toward HLA may thus play a causal role for the development of CVR and this opens new possibilities for the treatment of CVR...
  43. ncbi request reprint Predictive factors for anemia six and twelve months after orthotopic liver transplantation
    Joelle Guitard
    Multiorgan Transplant Unit, University Hospital, CHU Rangueil, France
    Transplantation 81:1525-31. 2006
    ..The aim of our study was to determine the prevalence and predictive factors for post-transplant anemia (PTA) at 6 (M6) and 12 (M12) months after orthotopic liver-transplant (OLT) in a cohort of 97 consecutive patients...
  44. ncbi request reprint Individualized mycophenolate mofetil dosing based on drug exposure significantly improves patient outcomes after renal transplantation
    Y Le Meur
    Department of Nephrology, University Hospital, Limoges, France
    Am J Transplant 7:2496-503. 2007
    ..9 mg*h/L; p < 0.0001). Therapeutic MPA monitoring using a limited sampling strategy can reduce the risk of treatment failure and acute rejection in renal allograft recipients 12 months posttransplant with no increase in adverse events...
  45. ncbi request reprint Thrombotic microangiopathy in a sirolimus-treated renal transplant patient receiving gemcitabine for lung cancer
    C Courtellemont
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Rangueil Larrey, Toulouse, France
    Clin Nephrol 67:114-8. 2007
    ..The reported incidence of gemcitabine-associated TMA in the literature is low, ranging from 0.015-0.31%...
  46. doi request reprint Duodenal villous atrophy: a cause of chronic diarrhea after solid-organ transplantation
    H Weclawiak
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Am J Transplant 11:575-82. 2011
    ..In conclusion, DVA is a frequent cause of chronic diarrhea in SOT recipients. MPA therapy is the most frequent cause of DVA. An OGD should be proposed to all transplant recipients who present with persistent diarrhea...
  47. ncbi request reprint Molecular evidence for nosocomial transmission of hepatitis C virus in a French hemodialysis unit
    J Izopet
    Laboratoire de Virologie, CHU Purpan, Toulouse, France
    J Med Virol 58:139-44. 1999
    ..This policy needs to be evaluated by large-scale prospective studies...
  48. doi request reprint Incidence and predictive factors for infectious disease after rituximab therapy in kidney-transplant patients
    N Kamar
    Department of Nephrology, Dialysis and Multi Organ Transplantation, INSERM U858, CHU Rangueil, Toulouse, France
    Am J Transplant 10:89-98. 2010
    ..After kidney transplantation, the use of rituximab is associated with a high risk of infectious disease and death related to infectious disease...
  49. ncbi request reprint Renal side effects of adefovir in hepatitis B virus-(HBV) positive kidney allograft recipients
    N Kamar
    Nephrology, Dialysis and Multiorgan Transplant Unit, CHU Rangueil, Toulouse, France
    Clin Nephrol 71:36-42. 2009
    ..The purpose of this study was to evaluate the renal side-effects of adefovir therapy in kidney-transplant (KT) recipients with chronic hepatitis B virus (HBV) infection, who have become resistant to lamivudine therapy...
  50. ncbi request reprint Hepatitis C virus-related kidney disease: an overview
    N Kamar
    Department of Nephrology, CHU Rangueil, Toulouse University Hospital, Toulouse, France
    Clin Nephrol 69:149-60. 2008
    ..In liver-transplant patients, in addition to anti-HCV therapy, rituximab might be also used...
  51. ncbi request reprint An unusual cause of acute renal failure in a kidney transplant recipient: salmonella enteritidis post-infectious glomerulonephritis
    A Pillet
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Rangueil, Toulouse, France
    Clin Nephrol 67:321-4. 2007
    ..A few cases of acute renal failure with glomerular syndrome, caused by S. enteritidis infection, have been reported in the literature, but none have been proven by histological findings...
  52. doi request reprint Hepatitis E virus-related cirrhosis in kidney- and kidney-pancreas-transplant recipients
    N Kamar
    Department of Nephrology, Dialysis and Multi Organ Transplantation, and INSERM U858, IFR 31, CHU Rangueil, Toulouse, France
    Am J Transplant 8:1744-8. 2008
    ..In both cases, a liver biopsy showed cirrhosis. We conclude that HEV infection cannot only evolve to chronic hepatitis, but can also be responsible for rapidly progressing cirrhosis in organ-transplant patients...
  53. ncbi request reprint Severe cytomegalovirus ureteritis in a renal allograft recipient with negative CMV monitoring
    Christophe Vaessen
    Department of Urology and Renal Transplantation, Hopital Rangueil, Toulouse, France
    Nephrol Dial Transplant 20:227-30. 2005
  54. ncbi request reprint Evidence that clearance of hepatitis C virus RNA after alpha-interferon therapy in dialysis patients is sustained after renal transplantation
    Nassim Kamar
    Department of Nephrology, Dialysis and Transplantation, CHU Rangueil, Toulouse, France
    J Am Soc Nephrol 14:2092-8. 2003
    ..In conclusion, hemodialysis patients waiting for a RT need to be treated with alpha-IFN because when HCV RNA clearance occurred, they experienced no relapse after transplantation despite chronic immunosuppressive treatment...
  55. doi request reprint Polyoma BK virus-associated nephropathy in kidney-transplant patients: Effects of leflunomide on T-cell functions and disease outcome
    Cindy Canivet
    INSERM U MR, Toulouse, France
    Int Immunopharmacol 9:1131-6. 2009
    ..The aim of this study was to assess i) T-cell functions before and after conversion from MMF to leflunomide in kidney-transplant patients with PVAN, and ii) effects of leflunomide on PVAN outcome...
  56. doi request reprint Hepatitis E virus: what transplant physicians should know
    N Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Am J Transplant 12:2281-7. 2012
    ..In this comprehensive minireview, we summarize the current knowledge on HEV infection in transplant patients, that is, its prevalence, incidence, natural history and therapy...
  57. ncbi request reprint Combined use of tacrolimus and sirolimus in de novo renal transplant patients: current data
    D Ribes
    Multiorgan Transplant Unit, University Hospital, Toulouse, France
    Transplant Proc 37:2813-6. 2005
    ..5 to 2 mg/d, or SRL troughs ranging from 8 to 12 ng/mL with conventional doses of tacrolimus, are associated with reduced renal function, higher blood pressure, and an increase in serum lipids compared with MMF/tacrolimus therapy...
  58. doi request reprint Biological changes after liver transplantation according to the presence or not of graft steatosis
    F Muscari
    Digestive and Liver Transplantation Department, CHU Rangueil, Toulouse, France
    Transplant Proc 40:3562-5. 2008
    ..To assess the consequences of graft steatosis on postoperative liver function as compared with normal liver grafts...
  59. doi request reprint [Epidemiological description of patients with neurological conditions in kidney transplant recipients]
    N Mingat
    Service d Urologie, transplantation rénale et andrologie, CHU Rangueil, TSA 50032, 31059 Toulouse, France
    Prog Urol 20:503-7. 2010
    ..The aim of this study was to describe the epidemiology of neuropathic bladder in kidney transplant patients...
  60. ncbi request reprint Prevalence of cryoglobulinemia and autoimmunity markers in renal-transplant patients
    S Faguer
    Nephrology, Dialysis, and Multiorgan Transplant Unit, University Hospital, CHU Rangueil, Toulouse, France
    Clin Nephrol 69:239-43. 2008
    ..To examine the prevalence of cryoglobulinemia (Cryo) and autoimmune markers in renal-transplant recipients in a stable condition, and to determine its risk factors and impact upon allograft function...
  61. doi request reprint Indications for and barriers to preemptive kidney transplantation: a review
    S Kallab
    Department of Nephrology, Dialysis and Organ Transplantation, INSERM U858, CHU Rangueil, Toulouse, France
    Transplant Proc 42:782-4. 2010
    ..It can be proposed to all patients, but still needs to be evaluated for repeat transplantation. The main barriers are organ-allocation policies and late referral of patients to transplantation centers...
  62. ncbi request reprint Aminothiols and allantoin in chronic dialysis patients: effects of hemodialysis sessions
    E Causse
    CHU Rangueil, Toulouse University, France
    Clin Nephrol 73:51-7. 2010
    ..Serum samples were collected before and after hemodialysis sessions. Total homocysteine, cysteine, glutathione, cysteinylglycine, uric acid, hypoxanthine, and allantoin were measured by capillary electrophoresis...
  63. doi request reprint Thymoglobulin induction and sirolimus versus tacrolimus in kidney transplant recipients receiving mycophenolate mofetil and steroids
    Denis Glotz
    Department of Nephrology, Saint Louis Hospital, Paris, France
    Transplantation 89:1511-7. 2010
    ....
  64. doi request reprint Pharmacodynamic monitoring of the conversion from mycophenolate mofetil to enteric-coated mycophenolate sodium in stable kidney-allograft recipients
    Torsten Bohler
    INSERM U858, Equipe 10, IFR 31, Institut Louis Bugnard, Batiment L3, CHU Rangueil, France
    Int Immunopharmacol 8:769-73. 2008
    ....
  65. ncbi request reprint Ribavirin pharmacokinetics in renal and liver transplant patients: evidence that it depends on renal function
    Nassim Kamar
    Department of Nephrology, Dialysis and Transplantation, CHU Rangueil, Toulouse, France
    Am J Kidney Dis 43:140-6. 2004
    ..Ribavirin is approved for the treatment of chronic hepatitis C virus (HCV) infection. However, no recommendation exists for dosing patients with impaired renal function...
  66. ncbi request reprint Treatment of hepatitis C-virus-related glomerulonephritis
    N Kamar
    Department of Nephrology, Dialysis, and Multiorgan Transplantation, CHU Rangueil, Toulouse University Hospital, Toulouse, France
    Kidney Int 69:436-9. 2006
    ..During the acute phase, plasmapheresis and steroid pulses can be used. However, future prospective, controlled, and randomized studies are still required to establish evidence-based guidelines to treat HCV-related glomerulopathies...
  67. ncbi request reprint Impact of early or delayed cyclosporine on delayed graft function in renal transplant recipients: a randomized, multicenter study
    N Kamar
    Department of Nephrology Transplantation, Hopital Rangueil, Toulouse, France
    Am J Transplant 6:1042-8. 2006
    ..5% of delayed CsA-ME patients (n.s.). Both regimens were well tolerated. These data suggest that early or delayed introduction of CsA-ME results in similar renal function in renal transplant patients regardless of DGF risk level...
  68. doi request reprint Hepatitis E virus-induced neurological symptoms in a kidney-transplant patient with chronic hepatitis
    N Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Am J Transplant 10:1321-4. 2010
    ..The discovery of quasispecies compartmentalization and its temporal association suggests that neurological symptoms could be linked to the emergence of neurotropic variants...
  69. ncbi request reprint Treatment of focal segmental glomerular sclerosis with rituximab: 2 case reports
    N Kamar
    Department of Nephrology, Dialysis and Multi Organ Transplantation, Toulouse University Hospital, Toulouse, France
    Clin Nephrol 67:250-4. 2007
    ..Primary focal segmental glomerular sclerosis (FSGS) recurs in 20 - 40% of patients after kidney transplantation. Rituximab has been used to treat several glomerular diseases...
  70. ncbi request reprint Does cyclosporine have a beneficial effect on the course of chronic hepatitis C infection after renal transplantation?
    N Kamar
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Rangueil, Toulouse, France
    Transplant Proc 38:1329-32. 2006
    ..Cyclosporine might have beneficial effects on the natural course of HCV infection after renal transplantation...
  71. ncbi request reprint Aspergillus fumigatus-related spondylodiscitis in a heart transplant patient successfully treated with voriconazole
    H Weclawiak
    Multiorgan Transplant Unit, CHU Rangueil, 1 avenue Jean Poulhes, 31059 Toulouse Cedex 9, France
    Transplant Proc 39:2627-8. 2007
    ..A percutaneous needle biopsy of the intervertebral disc yielded Aspergillus fumigatus. The patient had no evidence of lung aspergillosis, but did have maxillary sinusitis. He was successfully treated with voriconazole...
  72. ncbi request reprint Transient renal effects of sildenafil in male kidney transplant recipients
    B Malavaud
    Department of Urology and Renal Transplantation, INSERM Unit 388, Hopital Rangueil, Toulouse, France
    Transplantation 72:1331-3. 2001
    ..It also induces systemic vasodilation, resulting in a minor decrease in blood pressure. We evaluated the effect of one dose of sildenafil on graft function and hemodynamics in impotent male transplant recipients...
  73. ncbi request reprint Factors accelerating liver fibrosis progression in renal transplant patients receiving ribavirin monotherapy for chronic hepatitis C
    Nassim Kamar
    Department of Virology, CHU Purpan, Toulouse, France
    J Med Virol 76:61-8. 2005
    ..Severe chronic hemolysis is responsible for iron overload, liver iron deposition, and an acceleration in the progression of liver fibrosis...
  74. ncbi request reprint Natural history of hepatitis C virus-related liver fibrosis after renal transplantation
    Nassim Kamar
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Rangueil, Toulouse, Paris, France
    Am J Transplant 5:1704-12. 2005
    ..The diversification of the HVR-1 might be used to predict liver fibrosis outcome...
  75. ncbi request reprint Treatment of hepatitis C virus infection (HCV) after renal transplantation: implications for HCV-positive dialysis patients awaiting a kidney transplant
    Nassim Kamar
    Multiorgan Transplant Unit, CHU Rangueil, Toulouse, France
    Transplantation 82:853-6. 2006
    ..Finally, when HCV-positive dialysis patients with a sustained virological response undergo successful renal transplantation, very few suffer a virological relapse, thus emphasizing that these patients were cured...
  76. ncbi request reprint Alpha-interferon therapy for chronic hepatitis C may induce acute allograft rejection in kidney transplant patients with failed allografts
    Hugo Wéclawiack
    Department of Nephrology, CHU Rangueil, 1 av Jean Poulhes, 31059, Toulouse Cedex 9, France
    Nephrol Dial Transplant 23:1043-7. 2008
    ..Conversely, if these HCV(+) KT patients lose their allograft, re-transplantation might be contemplated provided alphaIFN therapy has been attempted...
  77. doi request reprint Cytomegalovirus prophylaxis with valganciclovir in cytomegalovirus-seropositive kidney-transplant patients
    Hugo Weclawiak
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Rangueil, Toulouse, France
    J Med Virol 80:1228-32. 2008
    ..5% (n=12) of patients, of whom two had two or more consecutive HCMV DNAemias. Valganciclovir prophylaxis in HCMV-seropositive kidney-transplant patients is effective for preventing cytomegalovirus disease...
  78. ncbi request reprint Induction therapy with either anti-CD25 monoclonal antibodies or rabbit antithymocyte globulins in liver transplantation for hepatitis C
    Nassim Kamar
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Toulouse, Rangueil, France
    Clin Transplant 19:83-9. 2005
    ..The aim of our sequential study was to assess the safety and efficacy of induction therapy using either rabbit antithymocyte globulins (RATG) or anti-CD25 monoclonal antibodies...
  79. ncbi request reprint Rituximab therapy for de novo mixed cryoglobulinemia in renal transplant patients
    Grégoire Basse
    Multiorgan Transplant Unit, University Hospital, CHU Rangueil, Toulouse, France
    Transplantation 80:1560-4. 2005
    ..e., rituximab). Thus, this provides the rationale to use rituximab for cryoglobulin-related graft dysfunction in RT patients...
  80. doi request reprint [Long-term outcome of patients with renal transplant and neural tube defect]
    O Abbo
    Service d Urologie, transplantation rénale et andrologie, CHU Rangueil, TSA 50032, 31059 Toulouse, France
    Prog Urol 22:339-43. 2010
    ..To evaluate the long term outcome of renal transplant in patients with a neural tube defect causing voiding dysfunctions...
  81. doi request reprint [Monitoring of calcineurin inhibitors induced-nephrotoxicity]
    N Kamar
    Service de Nephrologie, Dialyse et Transplantation d organes, CHU de Toulouse Rangueil, 1, avenue Jean Poulhes, TSA 50032, 31059 Toulouse cedex 09, France
    Nephrol Ther 4:S13-S17. 2008
    ..CNIs dose reduction or conversion to proliferating signal inhibitors may be a therapeutic alternative...
  82. ncbi request reprint Long-term evolution of lymphocytes subsets after induction therapy based on continuous versus discontinuous administration of anti-thymocyte globulins in renal-transplant patients
    L Esposito
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Rangueil, Toulouse, France
    Transplant Proc 37:785-7. 2005
    ..The aim of our retrospective study was to assess the long-term evolution of lymphocyte subsets after two modes of administration of anti-thymocyte globulin (ATG) after renal transplantation...
  83. ncbi request reprint [Syphilis hepatitis and liver transplantation]
    B Camara
    Service de Nephrologie, Dialyse et Transplantation, CHU de Rangueil, 1, avenue Jean Poulhes, TSA 50032, 31059 Toulouse cedex 09, France
    Med Mal Infect 37:121-3. 2007
    ..Cytolysis rapidly, and cholestasis progressively disappeared. IgM FTA-abs became negative, whereas VDRL and TPHA titers decreased slightly over time...
  84. ncbi request reprint Hypercalciuria induced by a high dose of cinacalcet in a renal-transplant recipient
    L Esposito
    Department of Nephrology, Dialysis and Multi Organ Transplantation, CHU Purpan, Toulouse University Hospital, Toulouse, France
    Clin Nephrol 68:245-8. 2007
    ..We conclude that cinacalcet should be used with caution in renal-transplant patients. Further investigations are required to determine the best way to use this drug in this setting...
  85. ncbi request reprint Cyclosporin nephrotoxicity: pathophysiology and comparison with FK-506
    J L Ader
    Laboratoire d Explorations Fonctionnelles Rénales et Métaboliques, et Unité INSERM 388, Rangueil University Hospital, Toulouse, France
    Curr Opin Nephrol Hypertens 7:539-45. 1998
    ....
  86. ncbi request reprint Efficacy and safety of induction therapy with rabbit antithymocyte globulins in liver transplantation for hepatitis C
    N Kamar
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Toulouse Rangueil, 31059 Toulouse Cedex 9, France
    Transplant Proc 36:2757-61. 2004
    ..The aim of our study was to assess the safety and efficacy of induction therapy using rabbit antithymocyte globulin antibodies (RATG)...
  87. ncbi request reprint Follow-up of 28 HCMV seropositive renal-transplant recipients: comparison of clinical, biological and virological parameters in the groups of treated versus untreated infected patients
    Nassim Kamar
    Unité de Transplantation d Organes, Hopital Rangueil, CHU Toulouse, Toulouse, France
    J Clin Virol 33:35-42. 2005
    ..A pre-emptive strategy for prevention of Human Cytomegalovirus (HCMV) disease depends on accurate detection of HCMV infection and clinical and/or biological abnormalities...
  88. ncbi request reprint Tamoxifen therapy in kidney-transplant patients presenting with severe encapsulating peritoneal sclerosis after treatment for acute humoral rejection
    Abdellatif Ould Mohamed
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Exp Clin Transplant 7:164-7. 2009
    ..Its mortality rate is approximately 30%, despite treatment with total parenteral nutrition, surgery, tamoxifen, or immunosuppressants...
  89. doi request reprint No evidence of occult hepatitis C virus (HCV) infection in serum of HCV antibody-positive HCV RNA-negative kidney-transplant patients
    Florence Nicot
    INSERM, U563, Toulouse, France
    Transpl Int 23:594-601. 2010
    ..No biochemical or virologic relapse was seen during follow-up. The absence of HCV relapse in formerly HCV-infected immunocompromised patients suggests the complete eradication of HCV after its elimination while on dialysis...
  90. pmc Convenient biological assay for polyethylene glycol-interferons in patients with hepatitis C
    Anne Boulestin
    Laboratoire de Virologie EA 2046 IFR 30, CHU Purpan, Place du Dr Baylac, TSA 40031, 31059 Toulouse Cedex 9, France
    Antimicrob Agents Chemother 48:3610-2. 2004
    ..Human serum and ribavirin did not interfere with the assay. This bioassay was successfully used for assaying PEG-IFN-alpha 2a and PEG-IFN-alpha 2b in serum samples from patients undergoing combination therapy...
  91. ncbi request reprint Genetic heterogeneity of the NS5A gene of hepatitis C virus and early response to interferon-alpha
    Anne Boulestin
    Laboratoire de Virologie, Centre Hospitalier Universitaire Purpan, Toulouse, France
    J Infect Dis 188:1367-70. 2003
    ..5 log (early responders) were similarly analyzed. In the 2 groups, the PKRbd evolved similarly over the first 24 h. Selection of resistant HCV variants is unlikely to explain primary resistance to IFN-alpha...
  92. doi request reprint Cytokines correlate with age in healthy volunteers, dialysis patients and kidney-transplant patients
    Torsten Bohler
    INSERM U 858 EQ 10, Institut Louis Bugnard, 1 Ave J Poulhès, CHU Rangueil, 3100 Toulouse, France
    Cytokine 45:169-73. 2009
    ....
  93. ncbi request reprint Monitoring human cytomegalovirus (HCMV) in HCMV-seropositive orthotopic liver-transplant recipients by means of quantitative real-time polymerase chain reaction
    Catherine Mengelle
    Laboratoire de Virologie, Hopital Purpan, CHU Toulouse, Toulouse, France
    Exp Clin Transplant 4:537-43. 2006
    ....
  94. doi request reprint Negative impact of one-year anemia on long-term patient and graft survival in kidney transplant patients receiving calcineurin inhibitors and mycophenolate mofetil
    Nassim Kamar
    Department of Nephrology, Dialysis and Multiorgan Transplantation, Toulouse University Hospital, CHU Rangueil, Toulouse, France
    Transplantation 85:1120-4. 2008
    ....
  95. ncbi request reprint Evaluation of the efficacy and safety of a slow conversion from calcineurin inhibitor- to sirolimus-based therapies in maintenance renal-transplant patients presenting with moderate renal insufficiency
    Nassim Kamar
    Department of Nephrology Transplantation, Hopital Rangueil, Toulouse, France
    Transpl Int 20:128-34. 2007
    ..Overall, there was a significant increase in proteinuria from 0 (0-3.15) to 0.57 (0-4.85) g/day (P=0.002). Finally, the conversion was associated with a significant increase in lipids, and a significant decrease in hemoglobin levels...
  96. ncbi request reprint Twenty-four hour kinetics of hepatitis C virus and antiviral effect of alpha-interferon
    Anne Boulestin
    Laboratoire de Virologie EA 2046 IFR30, CHU Purpan, Toulouse, France
    J Med Virol 78:365-71. 2006
    ..Resistant HCV strains could be distinguished from sensitive viruses as early as a few hours after the beginning of the treatment...
  97. ncbi request reprint Sulfadiazine-related obstructive urinary tract lithiasis: an unusual cause of acute renal failure after kidney transplantation
    J Guitard
    Department of Nephrology, Dialysis and Transplantation, CHU Rangueil, Toulouse, France
    Clin Nephrol 63:405-7. 2005
    ..Six days later, he underwent surgery to retrieve an orange-colored, friable stone. Its spectrophotometric analysis confirmed that the stone consisted of N-acetyl sulfadiazine crystals...
  98. doi request reprint In vitro mitogen-stimulated T-cell from hepatitis C virus-positive liver transplantation candidates, increases T-cell activation markers and T-cell proliferation
    Cindy Canivet
    INSERM U858 I2MR, Equipe 10, CHU Rangueil, Toulouse, France
    Transpl Immunol 19:112-9. 2008
    ....
  99. doi request reprint Expanding the criteria of renal kidneys for transplantation: use of donors with acute renal failure
    Benjamin Deroure
    Department of Nephrology, Dialysis and Transplantation, Le Kremlin Bicetre, University Paris XI, APHP, France
    Nephrol Dial Transplant 25:1980-6. 2010
    ..Increased numbers of patients waiting for renal transplantation have led to widening selection criteria for grafts. Thus, we have evaluated the outcome of transplanted kidneys procured in the presence of acute renal failure (ARF)...
  100. doi request reprint Erectile dysfunction in liver transplant patients
    E Huyghe
    Department of Urology and Andrology, University Hospital, CHU Rangueil, Toulouse, France
    Am J Transplant 8:2580-9. 2008
    ..03), antidepressants (p = 0.04) and diuretics (p = 0.03). In conclusion, LT improves sexual activity, but ED is multifactorial and remains a long-term condition in the majority of patients...
  101. ncbi request reprint Sarcoidosis-related hypercalcemia in 3 chronic hemodialysis patients
    A Huart
    Nephrology, Hemodialysis and Multi Organ Transplantation Department, CHU Rangueil, Toulouse Cedex, France
    Clin Nephrol 65:449-52. 2006
    ..1999]. In the present paper, we report on 3 cases of sarcoidosis-related hypercalcemia in chronic hemodialysis patients with 3 different patterns, i.e. overt sarcoidosis, probable sarcoidosis, and recurrence of pre-dialysis sarcoidosis...