Rodrigue Rossignol

Summary

Country: France

Publications

  1. pmc Mitochondrial threshold effects
    Rodrigue Rossignol
    INSERM EMI 9929, Physiologie Mitochondriale, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, F 33076 Bordeaux cedex, France
    Biochem J 370:751-62. 2003
  2. ncbi Energy substrate modulates mitochondrial structure and oxidative capacity in cancer cells
    Rodrigue Rossignol
    Institute of Molecular Biology, University of Oregon, Eugene, Oregon, USA
    Cancer Res 64:985-93. 2004
  3. ncbi A replicating module as the unit of mitochondrial structure and functioning
    Roderick A Capaldi
    Institute of Molecular Biology, University of Oregon, Eugene, OR 97403 1229, USA
    Biochim Biophys Acta 1555:192-5. 2002
  4. ncbi Mobilization of adenine nucleotide translocators as molecular bases of the biochemical threshold effect observed in mitochondrial diseases
    Benjamin Faustin
    INSERM, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, F 33076 Bordeaux cedex, France
    J Biol Chem 279:20411-21. 2004
  5. doi Ultrastructure of the mitochondrion and its bearing on function and bioenergetics
    Giovanni Benard
    INSERM U688, Bordeaux, France
    Antioxid Redox Signal 10:1313-42. 2008
  6. ncbi Mitochondrial bioenergetics and structural network organization
    Giovanni Benard
    Institut National de la Sante et de la Recherche Medicale INSERM, U688 Physiopathologie Mitochondriale, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, F 33076 Bordeaux cedex, France
    J Cell Sci 120:838-48. 2007
  7. doi Influence of mitochondrial DNA level on cellular energy metabolism: implications for mitochondrial diseases
    Christophe Rocher
    U688 INSERM Université Victor Segalen Bordeaux2, 146 rue Leo Saignat, 33076, Bordeaux Cedex, France
    J Bioenerg Biomembr 40:59-67. 2008
  8. doi Mitochondrial fluidity matters. Focus on "Inherited complex I deficiency is associated with faster protein diffusion in the matrix of moving mitochondria"
    Giovanni Benard
    Am J Physiol Cell Physiol 294:C1123. 2008
  9. pmc Bronchial smooth muscle remodeling involves calcium-dependent enhanced mitochondrial biogenesis in asthma
    Thomas Trian
    Universite Bordeaux 2, Laboratoire de Physiologie Cellulaire Respiratoire, F 33076 Bordeaux, France
    J Exp Med 204:3173-81. 2007
  10. ncbi Hypoxia-inducible factor-1alpha, a key factor in the keratinocyte response to UVB exposure
    Hamid Reza Rezvani
    Inserm U876, University Bordeaux, and Centre Hospitalier Universitaire de Bordeaux, France
    J Biol Chem 282:16413-22. 2007

Collaborators

  • S James Remington
  • James Murray
  • Jan Willem Taanman
  • Roderick Capaldi
  • Catherine Godinot
  • Giovanni Benard
  • Thierry Letellier
  • Christophe Rocher
  • Denis Pierron
  • Benjamin Faustin
  • Hamid Reza Rezvani
  • Thomas Trian
  • Monique Malgat
  • Olivier Augereau
  • Laurence Pedespan
  • Pascal Reynier
  • Stéphane Allouche
  • Marie Laure Martin-Negrier
  • Marc Crouzet
  • Christine Bellanne-Chantelot
  • Giovani Benard
  • Patricia Amati-Bonneau
  • Didier Thoraval
  • Agnes Rotig
  • Delphine Feldmann
  • Benoit Arveiler
  • Erwann Pennarun
  • Benedicte Mousson de Camaret
  • Pascal Murail
  • Cécile Batandier
  • José Manuel Tunon-de-Lara
  • Patrick Berger
  • Roger Marthan
  • Debajyoti Ghosh
  • Pierre Olivier Girodet
  • Olga Ousova
  • Helder Fernandez
  • Sophie Dedieu
  • Nadege Bellance
  • Dominic James
  • Hugues Begueret
  • Francis Belloc
  • Philippe Parrone
  • Sophie North
  • Jean Marc Vernejoux
  • Alain Taieb
  • Hubert de Verneuil
  • Frederic Mazurier
  • Francesca DeGiorgi
  • Jeanne Dachary-Prigent
  • Jean Pierre Mazat

Detail Information

Publications12

  1. pmc Mitochondrial threshold effects
    Rodrigue Rossignol
    INSERM EMI 9929, Physiologie Mitochondriale, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, F 33076 Bordeaux cedex, France
    Biochem J 370:751-62. 2003
    ..In this review these different mitochondrial threshold effects are discussed, along with their molecular bases and the roles that they play in the presentation of mitochondrial diseases...
  2. ncbi Energy substrate modulates mitochondrial structure and oxidative capacity in cancer cells
    Rodrigue Rossignol
    Institute of Molecular Biology, University of Oregon, Eugene, Oregon, USA
    Cancer Res 64:985-93. 2004
    ..We compared our finding on HeLa cells with those for nontransformed fibroblasts to help distinguish the regulatory pathways...
  3. ncbi A replicating module as the unit of mitochondrial structure and functioning
    Roderick A Capaldi
    Institute of Molecular Biology, University of Oregon, Eugene, OR 97403 1229, USA
    Biochim Biophys Acta 1555:192-5. 2002
    ..This leads us to propose that a replicating module is the repeating unit of mitochondrial structure. Studies to examine heterogeneity of functioning within the organelle mass are briefly reviewed...
  4. ncbi Mobilization of adenine nucleotide translocators as molecular bases of the biochemical threshold effect observed in mitochondrial diseases
    Benjamin Faustin
    INSERM, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, F 33076 Bordeaux cedex, France
    J Biol Chem 279:20411-21. 2004
    ..We discuss how these transitions are sensitive to the steady state of oxidative phosphorylation functioning or tissue and analyze their consequences on the threshold effect...
  5. doi Ultrastructure of the mitochondrion and its bearing on function and bioenergetics
    Giovanni Benard
    INSERM U688, Bordeaux, France
    Antioxid Redox Signal 10:1313-42. 2008
    ..In this review, we delve into the link between mitochondrial structure and energy metabolism...
  6. ncbi Mitochondrial bioenergetics and structural network organization
    Giovanni Benard
    Institut National de la Sante et de la Recherche Medicale INSERM, U688 Physiopathologie Mitochondriale, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, F 33076 Bordeaux cedex, France
    J Cell Sci 120:838-48. 2007
    ..Our data demonstrate that the relationship between mitochondrial network organization and bioenergetics is bidirectional, and we provide a model for analyzing the metabolic signals involved in this crosstalk...
  7. doi Influence of mitochondrial DNA level on cellular energy metabolism: implications for mitochondrial diseases
    Christophe Rocher
    U688 INSERM Université Victor Segalen Bordeaux2, 146 rue Leo Saignat, 33076, Bordeaux Cedex, France
    J Bioenerg Biomembr 40:59-67. 2008
    ..Our results show that oxidative phosphorylation activities are under a tight control by the amount of mtDNA in the cell, and that the full complement of mtDNA molecules are necessary to maintain a normal energy production level...
  8. doi Mitochondrial fluidity matters. Focus on "Inherited complex I deficiency is associated with faster protein diffusion in the matrix of moving mitochondria"
    Giovanni Benard
    Am J Physiol Cell Physiol 294:C1123. 2008
  9. pmc Bronchial smooth muscle remodeling involves calcium-dependent enhanced mitochondrial biogenesis in asthma
    Thomas Trian
    Universite Bordeaux 2, Laboratoire de Physiologie Cellulaire Respiratoire, F 33076 Bordeaux, France
    J Exp Med 204:3173-81. 2007
    ..Thus, BSM in asthmatic patients is characterized by an altered calcium homeostasis that increases mitochondrial biogenesis, which, in turn, enhances cell proliferation, leading to airway remodeling...
  10. ncbi Hypoxia-inducible factor-1alpha, a key factor in the keratinocyte response to UVB exposure
    Hamid Reza Rezvani
    Inserm U876, University Bordeaux, and Centre Hospitalier Universitaire de Bordeaux, France
    J Biol Chem 282:16413-22. 2007
    ..We conclude that the broad impact of the HIF-1 transcription factor on gene expression could make it a key regulator of UV-responsive genes and photocarcinogenesis...
  11. ncbi Apoptotic-like mitochondrial events associated to phosphatidylserine exposure in blood platelets induced by local anaesthetics
    Olivier Augereau
    Physiologie Mitochondriale, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    Thromb Haemost 92:104-13. 2004
    ..Therefore, we propose that mitochondria engagement in an apoptotic pathway in platelets could lead to PS exposure without the participation of Ca(2+)...
  12. pmc New evidence of a mitochondrial genetic background paradox: impact of the J haplogroup on the A3243G mutation
    Denis Pierron
    1Université Bordeaux 1, Laboratoire d Anthropologie des Populations du Passé, UMR 5199 PACEA, 33400 Talence, France
    BMC Med Genet 9:41. 2008
    ....