Virginie Rondeau

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..Logistic regression analysis showed that neither Tf C2 nor its interaction with Al or with the epsilon4 allele of the ApoE were significantly associated with the risk of AD...

..We show that even when the frailty effects are fairly small in magnitude, they are important since they alter the results in a systematic pattern...

..As an illustration, such an approach is applied to a prospective cohort with recurrent events of follicular lymphomas, jointly modeled with death...

..e., the rehospitalizations of patients diagnosed with colorectal cancer. We show how to fit the model with recurrent events and time-dependent covariates using Andersen-Gill approach...

..The simulation study and the application demonstrate that the proposed approach yields satisfactory results and they illustrate the need to use a flexible variance-covariance structure for the random effects...

..89, P=0.036). However, geographic exposure to aluminum or silica from tap water was not associated with dementia. High consumption of aluminum from drinking water may be a risk factor for Alzheimer's disease...

..A prospective cohort (Paquid) with grouped survival data serves to illustrate the method which was used to analyze the relationship between environmental factors and the risk of dementia...

..We conclude that not enough epidemiological evidence supports a link between aluminum in drinking water and AD. The role of silica in drinking water has been less studied, and clear results have not yet emerged...

..We also propose parametrical approach. We evaluate the model by simulation studies and illustrate through a study of patients with follicular lymphoma...

..With additional information of frequency and duration of use, they will enable to develop exposure indices usable in epidemiological studies on farmers' health...

..Higher adherence to a Mediterranean-type diet is linked to lower risk for mortality and chronic diseases, but its association with cognitive decline is unclear...

..These associations can also be investigated using case-crossover studies. However, by definition, individual risk factors are not studied, and such studies analyze only dead subjects, which limits the statistical power...

..We studied individual characteristics that modify the relationship between particulate air pollution and mortality among elderly...

..In most longitudinal studies of problem opiate users, drop-outs are frequent, but not taken into account. However, missing data can induce important bias in parameters estimates...

..The aim of the PHYTONER study is to investigate the role of pesticides on neurobehavioral performances in French vineyard workers...

..This method is applied to the study of dementia in a cohort of old people, and to the possible effect of the concentration of aluminum and silica in drinking water on the risk of developing dementia...

..To assess whether immunodeficiency is associated with the most frequent non-AIDS-defining causes of death in the era of combination antiretroviral therapy (cART)...

..We illustrate this proposed model via detailed analysis of the effect of air pollution on school absenteeism based on data from the Southern California Children's Health Study...

..Indicators of air pollution were the mean concentration...

..Tobacco smoking is a major modifiable risk factor of these emergent conditions and almost half of these patients are regular smokers in resource-rich countries...

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