K Ritchie

Summary

Country: France

Publications

  1. ncbi Alcohol consumption and the risk of dementia
    Karen Ritchie
    Institut National de la Sante et de la Recherche Medicale, E0361 Epidemiology of Nervous System Pathologies, Hôpital La Colombière, Montpellier, France
    Lancet Neurol 2:333. 2003
  2. ncbi The neuroprotective effects of caffeine: a prospective population study (the Three City Study)
    K Ritchie
    INSERM U888 Nervous System Pathologies, Epidemiological and Clinical Research, La Colombière Hospital, Montpellier, France
    Neurology 69:536-45. 2007
  3. ncbi 'I think therefore I am': improving cognition
    Karen Ritchie
    French National Institute of Health and Medical Research INSERM, Unit E361 Pathologies of the Nervous System, La Colombière Hospital, Montpellier, France
    Curr Opin Psychiatry 19:570-4. 2006
  4. ncbi The dementias
    Karen Ritchie
    Institut National de la Sante et de la Recherche Medicale, EMI 99 30, Hôpital La Colombière, Montpellier, France
    Lancet 360:1759-66. 2002
  5. pmc Angiotensin-converting enzyme gene variants are associated with both cortisol secretion and late-life depression
    M L Ancelin
    1 INSERM, U1061, Montpellier, France 2 Univ Montpellier 1, Montpellier, France
    Transl Psychiatry 3:e322. 2013
  6. pmc Characteristics of hormone therapy, cognitive function, and dementia: the prospective 3C Study
    J Ryan
    INSERM U888, Nervous System Pathologies Epidemiological and Clinical Research, Hôpital La Colombière, BP 34493, 34093 Montpellier Cedex 5, France
    Neurology 73:1729-37. 2009
  7. ncbi Discrepancies between apolipoprotein E phenotyping and genotyping in the elderly
    A M Dupuy
    Department of Biochemistry, Lapeyronie Hospital, Montpellier, France
    Clin Chem Lab Med 39:405-13. 2001
  8. pmc A prospective study of diurnal cortisol and cognitive function in community-dwelling elderly people
    I Beluche
    INSERM, U888, University of Montpellier 1, Montpellier, France
    Psychol Med 40:1039-49. 2010
  9. ncbi [The Esprit Project: a longitudinal general population study of psychiatric disorders in France in subjects over 65 years old]
    M L Ancelin
    INSERM, E361, Montpellier, F 34093 France, Univ Montpellier 1, Montpellier, F 34000 France
    Encephale 32:S615-21. 2006
  10. ncbi Risk profiles for mild cognitive impairment and progression to dementia are gender specific
    S Artero
    INSERM U888, Nervous System Pathologies Epidemiological and Clinical Research, La Colombière Hospital, 34093 Montpellier Cedex 5, France
    J Neurol Neurosurg Psychiatry 79:979-84. 2008

Detail Information

Publications80

  1. ncbi Alcohol consumption and the risk of dementia
    Karen Ritchie
    Institut National de la Sante et de la Recherche Medicale, E0361 Epidemiology of Nervous System Pathologies, Hôpital La Colombière, Montpellier, France
    Lancet Neurol 2:333. 2003
  2. ncbi The neuroprotective effects of caffeine: a prospective population study (the Three City Study)
    K Ritchie
    INSERM U888 Nervous System Pathologies, Epidemiological and Clinical Research, La Colombière Hospital, Montpellier, France
    Neurology 69:536-45. 2007
    ..To examine the association between caffeine intake, cognitive decline, and incident dementia in a community-based sample of subjects aged 65 years and over...
  3. ncbi 'I think therefore I am': improving cognition
    Karen Ritchie
    French National Institute of Health and Medical Research INSERM, Unit E361 Pathologies of the Nervous System, La Colombière Hospital, Montpellier, France
    Curr Opin Psychiatry 19:570-4. 2006
    ..In the absence of a specific treatment for dementia, the effective management of cognitive symptoms is a clinical priority...
  4. ncbi The dementias
    Karen Ritchie
    Institut National de la Sante et de la Recherche Medicale, EMI 99 30, Hôpital La Colombière, Montpellier, France
    Lancet 360:1759-66. 2002
    ..While fundamental research works towards new biological treatment strategies, much remains to be done in the area of disease management and the development of appropriate models of long-term care...
  5. pmc Angiotensin-converting enzyme gene variants are associated with both cortisol secretion and late-life depression
    M L Ancelin
    1 INSERM, U1061, Montpellier, France 2 Univ Montpellier 1, Montpellier, France
    Transl Psychiatry 3:e322. 2013
    ..Whether this could represent a common pathophysiological mechanism linking HPA axis and late-life depression remains to be explored...
  6. pmc Characteristics of hormone therapy, cognitive function, and dementia: the prospective 3C Study
    J Ryan
    INSERM U888, Nervous System Pathologies Epidemiological and Clinical Research, Hôpital La Colombière, BP 34493, 34093 Montpellier Cedex 5, France
    Neurology 73:1729-37. 2009
    ..To examine the association between hormone therapy (HT) and cognitive performance or dementia, focusing on the duration and type of treatment used, as well as the timing of initiation of HT in relation to the menopause...
  7. ncbi Discrepancies between apolipoprotein E phenotyping and genotyping in the elderly
    A M Dupuy
    Department of Biochemistry, Lapeyronie Hospital, Montpellier, France
    Clin Chem Lab Med 39:405-13. 2001
    ..Our results indicate that transcriptional modulation and post-transductional modifications in normal ageing and in aged-related diseases may explain in part discrepancies between gene analysis and protein characterisation...
  8. pmc A prospective study of diurnal cortisol and cognitive function in community-dwelling elderly people
    I Beluche
    INSERM, U888, University of Montpellier 1, Montpellier, France
    Psychol Med 40:1039-49. 2010
    ..However, the causal relationship between stress and subsequent cognitive impairment remains unclear, notably because of the small number of gender-stratified prospective studies...
  9. ncbi [The Esprit Project: a longitudinal general population study of psychiatric disorders in France in subjects over 65 years old]
    M L Ancelin
    INSERM, E361, Montpellier, F 34093 France, Univ Montpellier 1, Montpellier, F 34000 France
    Encephale 32:S615-21. 2006
  10. ncbi Risk profiles for mild cognitive impairment and progression to dementia are gender specific
    S Artero
    INSERM U888, Nervous System Pathologies Epidemiological and Clinical Research, La Colombière Hospital, 34093 Montpellier Cedex 5, France
    J Neurol Neurosurg Psychiatry 79:979-84. 2008
    ..To examine risk factors for mild cognitive impairment (MCI) and progression to dementia in a prospective community-based study of subjects aged 65 years and over...
  11. doi Leisure activities and the risk of dementia in the elderly: results from the Three-City Study
    T N Akbaraly
    INSERM U888, Hôpital La Colombière, 39 Avenue Charles Flahault, BP 34493, 34093 Montpellier, Cedex 5, France
    Neurology 73:854-61. 2009
    ..The possibility that these associations may be driven by other proxies of CR was also examined...
  12. ncbi Classification criteria for mild cognitive impairment: a population-based validation study
    K Ritchie
    , INSERM E99 30 Epidemiology of Nervous System Pathologies, Montpellier, France
    Neurology 56:37-42. 2001
    ..2). CONCLUSION: MCI criteria perform poorly when applied to a representative population sample. The authors propose modifications to current diagnostic criteria to increase their capacity to detect incipient dementia...
  13. ncbi [Schizophrenic patients' length of stay: clinical factors of variability and consequences]
    D Capdevielle
    Service universitaire de psychiatrie adulte, Hôpital La Colombière, Centre Hospitalier Universitaire, Montpellier Cedex 5, France
    Encephale 35:90-6. 2009
    ..The clinical consequences of these changes were not, however, evaluated prior to the implementation of these changes...
  14. doi [Prevalence of psychiatric disorders in French general practice using the patient health questionnaire: comparison with GP case-recognition and psychotropic medication prescription]
    J Norton
    INSERM U888, Hôpital La Colombière, Universite Montpellier, Pavillon 42, 39, Avenue Charles Flahault, 34093 Montpellier Cedex 5, France
    Encephale 35:560-9. 2009
    ..Nearly half of cases go unnoticed and among those that are recognised, many do not receive adequate treatment. In France, there is limited research concerning the prevalence, detection and management of these conditions in primary care...
  15. ncbi Disability and mild cognitive impairment: a longitudinal population-based study
    S Artero
    French National Institute of Health and Medical Research, Val d'Aurelle Hospital, Montpellier, France
    Int J Geriatr Psychiatry 16:1092-7. 2001
    ..High pre-morbid levels of ability are seen to have a protective effect. A diagnosis of dementia should not therefore be required by persons with cognitive impairment applying for home help...
  16. ncbi Life-time history of suicide attempts and coronary artery disease in a community-dwelling elderly population
    S Artero
    INSERM, E361, Montpellier, France
    Int J Geriatr Psychiatry 21:108-12. 2006
    ..No study has, however, explored the question of whether persons suffering from CAD might also be at high risk of suicide attempts...
  17. pmc Designing prevention programmes to reduce incidence of dementia: prospective cohort study of modifiable risk factors
    K Ritchie
    INSERM, U888 Nervous System Pathologies Epidemiological and Clinical Research, La Colombière Hospital, 34093 Montpellier Cedex 5, France
    BMJ 341:c3885. 2010
    ..To estimate the percentage reduction in incidence of dementia that would be obtained if specific risk factors were eliminated...
  18. ncbi Prevalence of DSM-IV psychiatric disorder in the French elderly population
    K Ritchie
    Institut National de la Sante et de la Recherche Medicale INSERM, E 0361 Pathologies of the Nervous System, Montpellier, France
    Br J Psychiatry 184:147-52. 2004
    ..France has high rates of psychotropic drug consumption and suicide in the elderly population, but it has not yet been possible to determine whether this is due to exceptionally high morbidity rates...
  19. doi Lipid levels and cardiovascular risk in elderly women: a general population study of the effects of hormonal treatment and lipid-lowering agents
    A M Dupuy
    INSERM U888, Montpellier, France
    Climacteric 11:74-83. 2008
    ..To evaluate plasma lipid levels in elderly women in the general population as a function of use of lipid-lowering agents (LLA) and hormone therapy (HT)...
  20. pmc Long-term association of food and nutrient intakes with cognitive and functional decline: a 13-year follow-up study of elderly French women
    Marie Noël Vercambre
    Institut National de la Sante et de la Recherche Medicale, ERI 20, EA 4045, and Institut Gustave Roussy, Villejuif, France
    Br J Nutr 102:419-27. 2009
    ..These results are consistent with a possible long-term neuroprotective effect of dietary fibre, n-3 polyunsaturated fats and B-group vitamins, and support dietary intervention to prevent cognitive decline...
  21. ncbi The detection of mild cognitive impairment in the general practice setting
    S Artero
    French National Institute of Health and Medical Research, INSERM EMI 9930 Epidemiology of Nervous System Pathologies, Montpellier, France
    Aging Ment Health 7:251-8. 2003
    ..It may be potentially feasible for the family practitioner to verify cognitive complaints and to screen for MCI with a high degree of accuracy using a brief test battery derived from empirical observations in population studies...
  22. ncbi The relationship between apolipoprotein E4 and lipid metabolism is impaired in Alzheimer's disease
    A M Dupuy
    Department of Biochemistry, Lapeyronie Hospital, Montpellier, France
    Gerontology 47:213-8. 2001
    ..This lipid abnormality may further contribute to the progression of AD...
  23. doi [Severe depression : environmental factors of severe depression : depression in parents]
    K Ritchie
    INSERM, U888 Pathologies du Système Nerveux Recherche Epidémiologique et Clinique, Montpellier
    Encephale 35:S296-300. 2009
    ..A number of questions remain to be explored ; the effect of the age of the child when the parent becomes depressed, the differential impact according to the child's sex, and the effect of duration of exposure...
  24. ncbi Lifelong endocrine fluctuations and related cognitive disorders
    M L Ancelin
    INSERM, E361, Montpellier, F 34093 France
    Curr Pharm Des 11:4229-52. 2005
    ....
  25. doi Elevated plasma fibrin D-dimer as a risk factor for vascular dementia: the Three-City cohort study
    L Carcaillon
    INSERM Unit 780, Cardiovascular Epidemiology, Villejuif
    J Thromb Haemost 7:1972-8. 2009
    ..However, few studies have investigated these associations in the elderly. Moreover, vascular factors may be involved in dementia. Data on the relationship between hemostatic biomarkers and dementia remain scarce...
  26. ncbi Use of the PRIME-MD Patient Health Questionnaire for estimating the prevalence of psychiatric disorders in French primary care: comparison with family practitioner estimates and relationship to psychotropic medication use
    Joanna Norton
    Institut National de la Sante et de la Recherche Medicale INSERM, U888, Hôpital La Colombière, Pavillon 42, 39 av Charles Flahault, BP 34493, 34093 Montpellier Cedex 5, France
    Gen Hosp Psychiatry 29:285-93. 2007
    ....
  27. doi Excessive daytime sleepiness is an independent risk indicator for cardiovascular mortality in community-dwelling elderly: the three city study
    Jean Philippe Empana
    INSERM U909, Cardiovascular Epidemiology and Sudden Death, Hopital Paul Brousse, Villejuif Cedex, France
    Stroke 40:1219-24. 2009
    ..We therefore estimated the risk of mortality for excessive daytime sleepiness (EDS) in community-dwelling elderly participating in the Three City Study...
  28. doi Persistence of abnormal cortisol levels in elderly persons after recovery from major depression
    Isabelle Beluche
    INSERM, U888, Montpellier, France
    J Psychiatr Res 43:777-83. 2009
    ....
  29. doi Life-time estrogen exposure and cognitive functioning in later life
    Joanne Ryan
    INSERM, U888, Montpellier F 34093, France
    Psychoneuroendocrinology 34:287-98. 2009
    ..Few studies have considered the influence of life-time estrogen exposure which may have an independent effect on cognition and/or modulate treatment response...
  30. pmc Lifetime hormonal factors may predict late-life depression in women
    Joanne Ryan
    INSERM, U888, Montpellier, F 34093 France
    Int Psychogeriatr 20:1203-18. 2008
    ..Fluctuating hormone levels are known to influence a woman's mood and well-being. This study aimed to determine whether lifetime hormonal markers are associated with late-life depression symptoms among elderly community-dwelling women...
  31. ncbi Distension of the carotid artery and risk of coronary events: the three-city study
    Nathalie Leone
    INSERM U700, Faculte de Medecine Xavier Bichat, 16 rue Henri Huchard, BP 416, 75018 Paris, France
    Arterioscler Thromb Vasc Biol 28:1392-7. 2008
    ..Arterial mechanical properties are of growing interest in the understanding of cardiovascular disease development. We aimed to determine the predictive value of carotid wall mechanics on coronary heart disease (CHD) in the Three-City study...
  32. pmc Association of adverse childhood environment and 5-HTTLPR Genotype with late-life depression
    Karen Ritchie
    INSERM, U888, Montpellier, France
    J Clin Psychiatry 70:1281-8. 2009
    ..Little is known, however, about the persistence of this vulnerability across the life span, although clinical studies of adult populations suggest that gene-environment interaction may diminish with aging...
  33. ncbi Hormonal therapy and depression: are we overlooking an important therapeutic alternative?
    Marie Laure Ancelin
    INSERM, U888, Montpellier, France
    J Psychosom Res 62:473-85. 2007
    ..This review aimed to examine evidence for the role of hormonal changes in the onset and course of depressive symptomatology and to assess the possible future role of hormonal therapies in the treatment of depression...
  34. doi Adverse childhood environment and late-life cognitive functioning
    Karen Ritchie
    INSERM, U888, Montpellier, France
    Int J Geriatr Psychiatry 26:503-10. 2011
    ..Clinical studies suggest that childhood maltreatment may cause nervous system changes and consequent cognitive disorder. The persistence of this association in late-life is examined...
  35. pmc Metabolic syndrome and onset of depressive symptoms in the elderly: findings from the three-city study
    Tasnime N Akbaraly
    Institut National de la Santé et de la Recherche Médicale INSERM U1061, F 34000 Montpellier, France
    Diabetes Care 34:904-9. 2011
    ....
  36. pmc Metabolic syndrome, its components, and mortality in the elderly
    Tasnime N Akbaraly
    Institut National de la Santé et de la Recherche Médicale INSERM Unité U 888, Universite Montpellier, Montpellier, France
    J Clin Endocrinol Metab 95:E327-32. 2010
    ..Our objectives were 1) to examine the association of MetS with the risk of all-cause and cause-specific mortality in a French elderly community-dweller cohort and 2) to determine the main components driving these associations...
  37. doi Gender and genotype modulation of the association between lipid levels and depressive symptomatology in community-dwelling elderly (the ESPRIT study)
    Marie Laure Ancelin
    Institut de la Santé et de la Recherche Médicale Inserm and University of Montpellier 1, Hôpital La Colombière, Centre hospitalier universitaire CHU, Montpellier, France
    Biol Psychiatry 68:125-32. 2010
    ..Lipids appear to mediate depressive vulnerability in the elderly; however, sex differences and genetic vulnerability have not been taken into account in previous prospective studies...
  38. doi Higher level of systemic C-reactive protein is independently predictive of coronary heart disease in older community-dwelling adults: the three-city study
    Celine Straczek
    INSERM U970, Paris Cardiovascular Research Center, Paris, France
    J Am Geriatr Soc 58:129-35. 2010
    ..To assess the association between systemic C-reactive protein (CRP) and incident coronary heart disease (CHD) in community-dwelling elderly people...
  39. pmc Disability and incident coronary heart disease in older community-dwelling adults: the Three-City Study
    Matthieu Plichart
    INSERM, U970, Paris Cardiovascular Research Centre PARCC, Paris, France
    J Am Geriatr Soc 58:636-42. 2010
    ..To prospectively assess the association between disability and incident fatal and nonfatal coronary heart disease (CHD) in older adults free of cardiovascular disease (CVD)...
  40. pmc Olive oil and cognition: results from the three-city study
    Claudine Berr
    INSERM U888 Pathologies du Systeme Nerveux Recherche Epidemiologique et Clinique, Universite Montpellier 1, Montpellier, France
    Dement Geriatr Cogn Disord 28:357-64. 2009
    ..Aim of the Study: Our objective was to examine the association between olive oil use, cognitive deficit and cognitive decline in a large elderly population...
  41. ncbi Revised criteria for mild cognitive impairment: validation within a longitudinal population study
    Sylvaine Artero
    INSERM E361, Hopital Gui de Chauliac, Universite de Montpellier 1, Montpellier, France
    Dement Geriatr Cogn Disord 22:465-70. 2006
    ..Current criteria perform poorly within the general population setting. Revisions have been proposed based on results obtained from clinical and epidemiological studies...
  42. ncbi The metabolic syndrome and the carotid artery structure in noninstitutionalized elderly subjects: the three-city study
    Jean Philippe Empana
    INSERM U780, Cardiovascular Team, Paris XI University, Hopital Paul Brousse, Villejuif Cedex, France
    Stroke 38:893-9. 2007
    ..We have investigated the frequency of the MetS and its association with the carotid artery structure in an elderly free-living population...
  43. pmc Caffeine, cognitive functioning, and white matter lesions in the elderly: establishing causality from epidemiological evidence
    Karen Ritchie
    INSERM, U888, Montpellier, France and University of Montpellier 1, Montpellier, France
    J Alzheimers Dis 20:S161-6. 2010
    ..The significant relationship observed between caffeine intake in women and lower cognitive decline is highly likely to be a true causal relationship and not a spurious association...
  44. pmc Retrospective identification and characterization of mild cognitive impairment from a prospective population cohort
    Karen Ritchie
    INSERM U, Universite de Montpellier, France
    Am J Geriatr Psychiatry 18:692-700. 2010
    ..This study retrospectively identifies cases of MCI and determines baseline criteria giving the highest discriminability. The ability of these criteria to increase current case detection specificity is estimated...
  45. ncbi The association between caffeine and cognitive decline: examining alternative causal hypotheses
    K Ritchie
    INSERM, Montpellier, France
    Int Psychogeriatr 26:581-90. 2014
    ..The assumed effect is that of reduced amyloid deposition, however, alternative pathways notably by reducing depression and diabetes type 2 risk have not been considered...
  46. ncbi Prediction of transition from cognitive impairment to senile dementia: a prospective, longitudinal study
    S Artero
    French National Institute of Health and Medical Research, INSERM EMI 9930 Epidemiology of Nervous System Pathologies, Montpellier, France
    Acta Psychiatr Scand 107:390-3. 2003
    ..The purpose of this investigation was to replicate the statistical approach used in a previous investigation (Toronto study) within a French population to determine the best predictive model for Alzheimer's disease (AD)...
  47. pmc Neuroanatomical localisation and clinical correlates of white matter lesions in the elderly
    S Artero
    Institut National de la Sante et de la Recherche Medicale, INSERM EMI 0361, Epidemiology of Nervous System Pathologies, Montpellier, France
    J Neurol Neurosurg Psychiatry 75:1304-8. 2004
    ....
  48. ncbi Prevalence of dementia in the elderly in Europe
    C Berr
    INSERM E361, Pathologies of the Nervous System, Clinical and Epidemiological Research, Hôpital La Colombière, 34093 Montpellier Cedex 5, France
    Eur Neuropsychopharmacol 15:463-71. 2005
    ..9% and 9.4%. We discuss the major problems limiting the use of these estimations, limits which may differ according to the area of application, be it etiological research or care provision...
  49. ncbi [Epidemiology of mental diseases in the elderly]
    S Artero
    INSERM E361, Universite Montpellier 1, 34000 Montpellier, Hôpital La Colombière, Pavillon 42, 39, Avenue Charles Flahault, BP 34493, 34093 Montpellier Cedex 5, France
    Encephale 32:S1091-4. 2006
  50. doi Do we really know the cause of death of the very old? Comparison between official mortality statistics and cohort study classification
    Annick Alperovitch
    INSERM U708 Neuroepidemiology, Institut National de la Sante et de la Recherche Medicale, Hopital de la Salpetriere, 75651, Paris Cedex 13, France
    Eur J Epidemiol 24:669-75. 2009
    ..85, 95% CI = 1.09-3.14). These findings raise questions about the validity of national mortality registers in very old persons. Disease-specific causes of death, especially vascular diseases, could be overestimated in this age group...
  51. pmc Drugs with anticholinergic properties, cognitive decline, and dementia in an elderly general population: the 3-city study
    Isabelle Carriere
    INSERM, U888, Universite Montpellier 1, Montpellier, France
    Arch Intern Med 169:1317-24. 2009
    ..Despite the high intake of medications with anticholinergic properties by community-dwelling elderly persons, the effects on cognitive decline and dementia have rarely been evaluated...
  52. doi [Schizophrenic patients' length of stay: mental health care implication and medicoeconomic consequences]
    D Capdevielle
    Service universitaire de psychiatrie adulte, Hôpital La Colombière, Centre Hospitalier Universitaire, 39, Avenue Charles Flahault, 34295 Montpellier Cedex 5, France
    Encephale 35:394-9. 2009
    ....
  53. ncbi Functional Vitamin E deficiency in ApoE4 patients with Alzheimer's disease
    Emilie Mas
    Department of Biochemistry, Lapeyronie Hospital, Montpellier, France
    Dement Geriatr Cogn Disord 21:198-204. 2006
    ..Our study strongly supports the hypothesis of an impairment of lipophilic antioxidant delivery to neuronal cells in AD leading to a tissular antioxidant deficiency which could facilitate oxidative stress...
  54. ncbi Sleep and depression
    Norifumi Tsuno
    E0361 Epidemiology of Nervous System Pathologies, Institut National de la Sante et de la Recherche Medicale INSERM, Hôpital La Colombière, Montpellier, France
    J Clin Psychiatry 66:1254-69. 2005
    ..The aim of this review is to summarize knowledge regarding the relationships between sleep and depression...
  55. doi Onset and relapse of psychiatric disorders following early breast cancer: a case-control study
    Catherine Gandubert
    INSERM, U888, Montpellier, F 34000, France
    Psychooncology 18:1029-37. 2009
    ..Our objective is to evaluate the mental status of primary early breast cancer survivors according to DSM-IV criteria, distinguishing new psychiatric diagnosis, which started after the cancer diagnosis from relapse...
  56. ncbi Is antioxidant therapy a viable alternative for mild cognitive impairment? Examination of the evidence
    Marie Laure Ancelin
    INSERM, U888, University of Montpellier 1, Montpellier, France
    Dement Geriatr Cogn Disord 24:1-19. 2007
    ....
  57. ncbi Prevalence, awareness, treatment, and control of hypertension in the elderly: the Three City study
    Pauline Brindel
    INSERM, U708, Paris, France
    J Hypertens 24:51-8. 2006
    ..To study management of hypertension in the elderly in a large population-based study and to evaluate the prevalence of hypertension and factors related to awareness, treatment, and control...
  58. ncbi Consumption of psychotropic medication in the elderly: a re-evaluation of its effect on cognitive performance
    Jacques Allard
    Sherbrooke Geriatric University Institute, Sherbrooke, Quebec, Canada
    Int J Geriatr Psychiatry 18:874-8. 2003
    ..Current evidence based on studies with numerous procedural shortenings supports the notion of the detrimental effect...
  59. pmc Hormonal treatment, mild cognitive impairment and Alzheimer's disease
    Joanne Ryan
    INSERM, U888, Montpellier, F 34093 France
    Int Psychogeriatr 20:47-56. 2008
    ....
  60. ncbi Alcohol consumption and carotid artery structure in older French adults: the Three-City Study
    Mahmoud Zureik
    National Institute of Health and Medical Research INSERM, Unit 508, Institut Pasteur de Lille, 1 rue Calmette, BP 245 59019 Lille, France
    Stroke 35:2770-5. 2004
    ..Several epidemiological studies have suggested a U-shaped association between alcohol consumption and cardiovascular risk. However, the modifications of vascular structure associated with alcohol consumption are largely unknown...
  61. ncbi [Epidemiological studies on aging in France: from the PAQUID study to the Three-City study]
    Annick Alperovitch
    INSERM, unité 360, Hopital de la Salpetriere, 75651 Paris, France
    C R Biol 325:665-72. 2002
    ..To measure the impact of the strategies on the incidence of dementia and the social burden of this disease will be an important public health objective in the near future...
  62. pmc Non-degenerative mild cognitive impairment in elderly people and use of anticholinergic drugs: longitudinal cohort study
    Marie L Ancelin
    INSERM, E361, Pathologies of the Nervous System, 34093 Montpellier, France
    BMJ 332:455-9. 2006
    ..To assess the potential of anticholinergic drugs as a cause of non-degenerative mild cognitive impairment in elderly people...
  63. ncbi IPA survey of brief cognitive screening instruments
    Kenneth I Shulman
    Department of Psychiatry, Sunnybrook and Women s, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
    Int Psychogeriatr 18:281-94. 2006
    ....
  64. ncbi Mild cognitive impairment
    Serge Gauthier
    McGill Center for Studies in Aging, Douglas Hospital, Montreal, Quebec, Canada
    Lancet 367:1262-70. 2006
    ..Other definitions and subtypes of mild cognitive impairment need to be studied as potential prodromes of Alzheimer's disease and other types of dementia...
  65. ncbi Elderly persons with elderly fathers - do they face additional risks?
    Karen Ritchie
    Int Psychogeriatr 20:427-9. 2008
  66. doi Memory complaints in healthy young and elderly adults: reliability of memory reporting
    Tiago Mendes
    Dementia Clinics, Institute of Molecular Medicine and Faculty of Medicine, University of Lisbon, Portugal
    Aging Ment Health 12:177-82. 2008
    ..In conclusion, there are differences in the reliability of memory reporting across the lifespan, younger subjects being more likely to correctly report good memory than older subjects...
  67. doi Late-life depression and mortality: influence of gender and antidepressant use
    Joanne Ryan
    Institut National de la Santé et de la Recherche Médicale Inserm U888, University of Montpellier, France
    Br J Psychiatry 192:12-8. 2008
    ..Depression may increase the risk of mortality among certain subgroups of older people, but the part played by antidepressants in this association has not been thoroughly explored...
  68. ncbi Determinants of excessive daytime sleepiness in a French community-dwelling elderly population
    Norifumi Tsuno
    INSERM Unité 888, Hôpital La Colombière, 39 Avenue Charles Flahault, Montpellier Cedex 5, France
    J Sleep Res 16:364-71. 2007
    ..A multivariate analysis revealed that the lifetime prevalence of manic and hypomanic episodes, snoring and gender (male) were independently associated with EDS. No independent association with other psychiatric disorders was found...
  69. ncbi Factors associated with changes in antidepressant use in a community-dwelling elderly cohort: the Three-City Study
    Agnès Soudry
    Institut National de la Santé et de la Recherche Médicale INSERM U708, Paris, France
    Eur J Clin Pharmacol 64:51-9. 2008
    ..This study aimed to examine changes in antidepressant use in an elderly population over a 2-year period and to determine which factors could predict these changes...
  70. ncbi Depressive symptoms, major depressive episode and cognition in the elderly: the three-city study
    Ophelia Godin
    INSERM U708, Universite Pierre et Marie Curie Paris 6, Paris, France
    Neuroepidemiology 28:101-8. 2007
    ..The objective of this study was to examine the relationship between depression and cognitive performances by using multiple measures of depressive state...
  71. ncbi Tea consumption is inversely associated with carotid plaques in women
    Stephanie Debette
    INSERM, U744, Lille, France
    Arterioscler Thromb Vasc Biol 28:353-9. 2008
    ..The aim of this study was to assess the relationship of tea consumption with common carotid artery intima-media thickness (CCA-IMT) and carotid plaques...
  72. ncbi Mild extrapyramidal signs and functional impairment in ageing
    Marcus Richards
    MRC National Survey of Health and Development, University College London, UK
    Int J Geriatr Psychiatry 17:150-3. 2002
    ..Little is known about the clinical significance of mild extrapyramidal signs (EPS) in elderly individuals. We investigated whether EPS are associated with functional impairment in older people with cognitive decline...
  73. ncbi The long and the short of it: are shorter periods of hospitalisation beneficial?
    Delphine Capdevielle
    Br J Psychiatry 192:164-5. 2008
    ..In the absence of clearer guidelines from researchers in this area, decisions about duration of hospitalisation risk being driven by economic rather than clinical considerations...
  74. doi Ascertaining late-life depressive symptoms in Europe: an evaluation of the survey version of the EURO-D scale in 10 nations. The SHARE project
    Erico Castro-Costa
    Institute of Psychiatry, Department of Health Services and Population Research, King s College London, London, UK
    Int J Methods Psychiatr Res 17:12-29. 2008
    ..The Affective Suffering sub-component had more robust cross-cultural validity than the Motivation sub-component...
  75. ncbi Cost utility of prenatal diagnosis
    Ian Bradbury
    Lancet 363:1164-5; author reply 1165. 2004
  76. ncbi Is deafness a disease of poverty? The association between socio-economic deprivation and congenital hearing impairment
    Haytham Kubba
    MRC Institute for Hearing Research scottish section, Glasgow Royal Infirmary, Glasgow, UK
    Int J Audiol 43:123-5. 2004
    ..There should be a strong emphasis on the needs of the socio-economically disadvantaged when planning services for hearing-impaired children...
  77. ncbi New insight into the association of apolipoprotein E genetic variants with carotid plaques and intima-media thickness
    Stephanie Debette
    Department of Neurology, University Hospital of Lille, Lille, France
    Stroke 37:2917-23. 2006
    ..Our aim was to test their association with 2 polymorphisms of the apolipoprotein E (apoE) gene, epsilon and -219G/T...
  78. doi Calf circumference is inversely associated with carotid plaques
    Stephanie Debette
    INSERM, U744, Lille, France
    Stroke 39:2958-65. 2008
    ....
  79. ncbi Contingent screening for Down syndrome is an efficient alternative to non-disclosure sequential screening
    Dave Wright
    Department of Mathematics and Statistics, University of Plymouth, UK
    Prenat Diagn 24:762-6. 2004
    ..Unlike non-disclosure sequential screening ('the Integrated test'), which requires all women to have markers in both trimesters, this allows a large proportion of the women to complete screening in the first trimester...