Sylvain Rheims

Summary

Country: France

Publications

  1. ncbi request reprint Nocturnal hypermotor seizures, suggesting frontal lobe epilepsy, can originate in the insula
    Philippe Ryvlin
    Department of Functional Neurology and Epileptology, Hospices Civils de Lyon and Université Claude Bernard Lyon 1, Lyon, France
    Epilepsia 47:755-65. 2006
  2. ncbi request reprint Analysis of clinical patterns and underlying epileptogenic zones of hypermotor seizures
    Sylvain Rheims
    Department of Functional Neurology and Epileptology, Hospices Civils de Lyon, Lyon, France
    Epilepsia 49:2030-40. 2008
  3. ncbi request reprint Excitatory GABA in rodent developing neocortex in vitro
    Sylvain Rheims
    Institut de Neurobiologie de la Mediterranee, Institut National de la Sante et de la Recherche Medicale U901, Universite de la Mediterranee, route de Luminy, Marseille, France
    J Neurophysiol 100:609-19. 2008
  4. ncbi request reprint Layer-specific generation and propagation of seizures in slices of developing neocortex: role of excitatory GABAergic synapses
    Sylvain Rheims
    Institut de Neurobiologie de la Mediterranee, Institut National de la Sante et de la Recherche Medicale U901, Universite de la Mediterranee, Marseille, France
    J Neurophysiol 100:620-8. 2008
  5. doi request reprint Inhibitory actions of the gamma-aminobutyric acid in pediatric Sturge-Weber syndrome
    Roman Tyzio
    INMED INSERM U901, Marseille, Paris, France
    Ann Neurol 66:209-18. 2009
  6. ncbi request reprint Postnatal changes in somatic gamma-aminobutyric acid signalling in the rat hippocampus
    Roman Tyzio
    INMED INSERM U901, Universite de la Mediterranee, 163, Avenue de Luminy, 13273 Marseille, France
    Eur J Neurosci 27:2515-28. 2008
  7. doi request reprint GABA action in immature neocortical neurons directly depends on the availability of ketone bodies
    Sylvain Rheims
    INMED INSERM U901, Universite de la Mediterranee, Marseille, France
    J Neurochem 110:1330-8. 2009
  8. doi request reprint Factors determining response to antiepileptic drugs in randomized controlled trials. A systematic review and meta-analysis
    Sylvain Rheims
    Hospices Civils de Lyon, Department of Functional Neurology and Epileptology, Institute for Children and Adolescents with Epilepsy IDEE, Lyon, France
    Epilepsia 52:219-33. 2011
  9. doi request reprint Hypermotor seizures in lateral and mesial parietal epilepsy
    Alexandra Montavont
    Epilepsy, Sleep and Pediatric Neurophysiology Dpt, HFME, Lyon University Hospital, Lyon, France
    Epilepsy Behav 28:408-12. 2013
  10. doi request reprint Choosing the tumoral epilepsy surgery candidate
    Sylvain Rheims
    Department of Functional Neurology and Epileptology, Hospices Civils de Lyon, Lyon, France INSERM U1028 CNRS UMR5292, Translational and Integrative Group in Epilepsy Research, Lyon Neuroscience Research Center, Lyon, France
    Epilepsia 54:91-6. 2013

Collaborators

Detail Information

Publications26

  1. ncbi request reprint Nocturnal hypermotor seizures, suggesting frontal lobe epilepsy, can originate in the insula
    Philippe Ryvlin
    Department of Functional Neurology and Epileptology, Hospices Civils de Lyon and Université Claude Bernard Lyon 1, Lyon, France
    Epilepsia 47:755-65. 2006
    ....
  2. ncbi request reprint Analysis of clinical patterns and underlying epileptogenic zones of hypermotor seizures
    Sylvain Rheims
    Department of Functional Neurology and Epileptology, Hospices Civils de Lyon, Lyon, France
    Epilepsia 49:2030-40. 2008
    ..Furthermore, HMS can include different forms of HM behaviors. Whether these clinical variations may be systematized and may reflect different locations of the epileptogenic zone (EZ) has not been evaluated yet...
  3. ncbi request reprint Excitatory GABA in rodent developing neocortex in vitro
    Sylvain Rheims
    Institut de Neurobiologie de la Mediterranee, Institut National de la Sante et de la Recherche Medicale U901, Universite de la Mediterranee, route de Luminy, Marseille, France
    J Neurophysiol 100:609-19. 2008
    ..In the companion paper, we show that the excitatory GABA drives layer-specific seizures in the immature neocortex...
  4. ncbi request reprint Layer-specific generation and propagation of seizures in slices of developing neocortex: role of excitatory GABAergic synapses
    Sylvain Rheims
    Institut de Neurobiologie de la Mediterranee, Institut National de la Sante et de la Recherche Medicale U901, Universite de la Mediterranee, Marseille, France
    J Neurophysiol 100:620-8. 2008
    ..In superficial layers, a persistent increase in excitability of pyramidal neurons caused by Em depolarization is associated with a transition from largely confined GABAergic IIS to ictal events that entrain the entire neocortex...
  5. doi request reprint Inhibitory actions of the gamma-aminobutyric acid in pediatric Sturge-Weber syndrome
    Roman Tyzio
    INMED INSERM U901, Marseille, Paris, France
    Ann Neurol 66:209-18. 2009
    ..We explored the properties of neurons from human pediatric SWS cortex in vitro and tested in particular whether gamma-aminobutyric acid (GABA) excites neurons in SWS cortex, as has been suggested for various types of epilepsies...
  6. ncbi request reprint Postnatal changes in somatic gamma-aminobutyric acid signalling in the rat hippocampus
    Roman Tyzio
    INMED INSERM U901, Universite de la Mediterranee, 163, Avenue de Luminy, 13273 Marseille, France
    Eur J Neurosci 27:2515-28. 2008
    ..Apparent hyperpolarizing GABA responses previously reported in the soma of CA3 pyramidal cells are probably due to cell depolarization during intracellular or whole-cell recordings...
  7. doi request reprint GABA action in immature neocortical neurons directly depends on the availability of ketone bodies
    Sylvain Rheims
    INMED INSERM U901, Universite de la Mediterranee, Marseille, France
    J Neurochem 110:1330-8. 2009
    ..Therefore, by inducing a hyperpolarizing shift in E(m) and modulating GABA signaling mode, KBs can efficiently control the excitability of neonatal cortical neurons...
  8. doi request reprint Factors determining response to antiepileptic drugs in randomized controlled trials. A systematic review and meta-analysis
    Sylvain Rheims
    Hospices Civils de Lyon, Department of Functional Neurology and Epileptology, Institute for Children and Adolescents with Epilepsy IDEE, Lyon, France
    Epilepsia 52:219-33. 2011
    ..However, such indirect comparisons raise various methodologic issues that may hamper their relevance...
  9. doi request reprint Hypermotor seizures in lateral and mesial parietal epilepsy
    Alexandra Montavont
    Epilepsy, Sleep and Pediatric Neurophysiology Dpt, HFME, Lyon University Hospital, Lyon, France
    Epilepsy Behav 28:408-12. 2013
    ..The last patient is awaiting surgery. Posterior cortex epilepsies, including those originating from the posterior cingulate cortex, can be responsible for HMSs. ..
  10. doi request reprint Choosing the tumoral epilepsy surgery candidate
    Sylvain Rheims
    Department of Functional Neurology and Epileptology, Hospices Civils de Lyon, Lyon, France INSERM U1028 CNRS UMR5292, Translational and Integrative Group in Epilepsy Research, Lyon Neuroscience Research Center, Lyon, France
    Epilepsia 54:91-6. 2013
    ..In these patients, the extent of tumor resection correlates with improved survival, progression-free survival, as well as with the chances of postoperative seizure control. ..
  11. doi request reprint Subcontinuous epileptiform activity after failed hippocampal radiosurgery
    Sylvain Rheims
    Hospices Civils de Lyon, Department of Functional Neurology and Epileptology, Lyon, France
    Epilepsia 52:1425-9. 2011
    ....
  12. ncbi request reprint Nocturnal frontal lobe epilepsy
    Philippe Ryvlin
    CTRS IDEE and Department of Functional Neurology and Epileptology, Neurological Hospital, Hospices Civiles de Lyon and Université Claude Bernard Lyon1, Lyon, France
    Epilepsia 47:83-6. 2006
    ..Further research is warranted in this field, keeping in mind that the neural networks underlying NFLE remain poorly known and might primarily involve extrafrontal brain regions in some patients...
  13. ncbi request reprint Long-term outcome of gamma-knife surgery in temporal lobe epilepsy
    Sylvain Rheims
    Department of Functional Neurology and Epileptology, Hospices Civils de Lyon, Lyon, France
    Epilepsy Res 80:23-9. 2008
    ..Either positive or negative results have been reported in studies with a maximum follow-up of 24 months. No long-term data have been published yet...
  14. ncbi request reprint Intrainsular functional connectivity in human
    Talal Almashaikhi
    Translational and Integrative Group in Epilepsy Research TIGER, Lyon s Neuroscience Research Centre, INSERM U1028, CNRS 5292, UCB Lyon 1, Lyon, France Pediatric Epilepsy Department, Hospices Civils de Lyon, Lyon, France Department of Clinical Physiology, Neurophysiology Division, Sultan Qaboos University Hospital, Muscat, Oman
    Hum Brain Mapp 35:2779-88. 2014
    ..The aim of this study was to analyze the functional connectivity within- and across-insular subregions, at both gyral and functional levels...
  15. ncbi request reprint Ipsilateral head deviation in frontal lobe seizures
    Sylvain Rheims
    Department of Functional Neurology and Epileptology, Neurological Hospital, Lyon, France
    Epilepsia 46:1750-3. 2005
    ..Whether both types of HD can be distinguished according to their clinical patterns has not yet been specifically investigated...
  16. pmc Epilepsy surgery: eligibility criteria and presurgical evaluation
    Philippe Ryvlin
    Department of Functional Neurology and Epileptology, Neurological Hospital, CTRS INSERM IDEE Institut Des Epilepsies de l Enfant et de l adolescent, Hospices Civils de Lyon, INSERM U821, Universite Claude Bernard Lyon 1, Lyon, France
    Dialogues Clin Neurosci 10:91-103. 2008
    ..The roles and specific features of the main types of presurgical investigations are reviewed...
  17. doi request reprint Risk of sudden unexpected death in epilepsy in patients given adjunctive antiepileptic treatment for refractory seizures: a meta-analysis of placebo-controlled randomised trials
    Philippe Ryvlin
    Department of Functional Neurology and Epileptology and Institute for Children and Adolescents with Epilepsy IDEE, Hospices Civils de Lyon, Lyon, F 69000, France
    Lancet Neurol 10:961-8. 2011
    ....
  18. pmc Greater response to placebo in children than in adults: a systematic review and meta-analysis in drug-resistant partial epilepsy
    Sylvain Rheims
    Department of Functional Neurology and Epileptology, Hospices Civils de Lyon, Lyon, France
    PLoS Med 5:e166. 2008
    ....
  19. doi request reprint Once-daily lamotrigine extended release for epilepsy management
    Sylvain Rheims
    Department of Functional Neurology and Epileptology, Hospices Civils de Lyon, Lyon, France
    Expert Rev Neurother 9:167-73. 2009
    ..Once-daily LTG-XR may represent a future option for patients with poor compliance to twice-daily immediate-release LTG...
  20. doi request reprint Retigabine for partial onset seizures
    Sylvain Rheims
    Department of Functional Neurology and Epileptology and Institute for Children and Adolescent with Epilepsy, Hospices Civils de Lyon, Lyon, France
    Expert Rev Neurother 12:509-17. 2012
    ..Long-term open-label extensions of these three pivotal trials are underway. RTG has recently been approved both in Europe and in the USA for the adjunctive treatment of partial-onset seizures in adults aged 18 years and above...
  21. pmc Peri-ictal pseudoprogression in patients with brain tumor
    Sylvain Rheims
    Service de Neuro Oncologie, Hospices Civils de Lyon, 59 Boulevard Pinel, 69003 Lyon, France
    Neuro Oncol 13:775-82. 2011
    ..This phenomenon is important to recognize in order to avoid futile therapeutic escalation...
  22. ncbi request reprint Pharmacotherapy for tonic-clonic seizures
    Sylvain Rheims
    Hospices Civils de Lyon and CRNL, INSERM U1028, CNRS 5292, Unité 301, Hopital Neurologique, 59 Bd Pinel, 69003, Lyon, France
    Expert Opin Pharmacother 15:1417-26. 2014
    ..In patients with sGTCS, AEDs for which the impact on this seizure type has been formally evaluated and which have demonstrated greater efficacy than placebo might preferentially be used, such as lacosamide, perampanel and topiramate. ..
  23. doi request reprint Patients' safety in the epilepsy monitoring unit: time for revising practices
    Sylvain Rheims
    aDepartment of Functional Neurology and Epileptology and Institute for Epilepsies IDEE, Hospices Civils de Lyon bINSERM U1028 CNRS UMR5292, Lyon Neuroscience Research Center, Lyon, France
    Curr Opin Neurol 27:213-8. 2014
    ....
  24. pmc Profile of perampanel and its potential in the treatment of partial onset seizures
    Sylvain Rheims
    Department of Functional Neurology and Epileptology and Institute for Children and Adolescent with Epilepsy, Hospices Civils de Lyon, Lyon, France Lyon Neuroscience Research Center, INSERM U1028 CNRS UMR 5292 Translational and Integrative Group in Epilepsy Research, Lyon, France
    Neuropsychiatr Dis Treat 9:629-37. 2013
    ..However, in the absence of a direct comparison between PER and other licensed antiepileptic drugs' efficacy and tolerability, the clinical advantages of PER over the other drugs in intractable partial epilepsy remains to be determined...
  25. ncbi request reprint Patient and physician preferences: impact on treatment effectiveness
    Sylvain Rheims
    Department of Functional Neurology and Epileptology and Institute for Children and Adolescent with Epilepsy IDEE, Hospices Civils de Lyon, INSERM U1028, CNRS UMR5292, Lyon Neuroscience Research Center, Translational and Integrative Group in Epilepsy Research, Lyon, France
    Epileptic Disord 14:242-7. 2012
    ....
  26. pmc Pregabalin for the management of partial epilepsy
    Philippe Ryvlin
    Service de Neurologie et d Epileptologie, Hopital Neurologique, Hospices Civils de Lyon, Universite Lyon 1, INSERM U821 and CTRS IDEE, Lyon, France
    Neuropsychiatr Dis Treat 4:1211-24. 2008
    ..During the last year on pregabalin, 3.7% of patients were seizure-free. Pregabalin appears to be a useful addition to the therapeutic armamentariun for the management of refractory partial epilepsy...