Sylvain Rheims

Summary

Country: France

Publications

  1. ncbi Nocturnal hypermotor seizures, suggesting frontal lobe epilepsy, can originate in the insula
    Philippe Ryvlin
    Department of Functional Neurology and Epileptology, Hospices Civils de Lyon and Université Claude Bernard Lyon 1, Lyon, France
    Epilepsia 47:755-65. 2006
  2. ncbi Analysis of clinical patterns and underlying epileptogenic zones of hypermotor seizures
    Sylvain Rheims
    Department of Functional Neurology and Epileptology, Hospices Civils de Lyon, Lyon, France
    Epilepsia 49:2030-40. 2008
  3. ncbi Excitatory GABA in rodent developing neocortex in vitro
    Sylvain Rheims
    Institut de Neurobiologie de la Mediterranee, Institut National de la Sante et de la Recherche Medicale U901, Universite de la Mediterranee, route de Luminy, Marseille, France
    J Neurophysiol 100:609-19. 2008
  4. ncbi Layer-specific generation and propagation of seizures in slices of developing neocortex: role of excitatory GABAergic synapses
    Sylvain Rheims
    Institut de Neurobiologie de la Mediterranee, Institut National de la Sante et de la Recherche Medicale U901, Universite de la Mediterranee, Marseille, France
    J Neurophysiol 100:620-8. 2008
  5. ncbi Inhibitory actions of the gamma-aminobutyric acid in pediatric Sturge-Weber syndrome
    Roman Tyzio
    INMED INSERM U901, Marseille, Paris, France
    Ann Neurol 66:209-18. 2009
  6. ncbi Postnatal changes in somatic gamma-aminobutyric acid signalling in the rat hippocampus
    Roman Tyzio
    INMED INSERM U901, Universite de la Mediterranee, 163, Avenue de Luminy, 13273 Marseille, France
    Eur J Neurosci 27:2515-28. 2008
  7. ncbi GABA action in immature neocortical neurons directly depends on the availability of ketone bodies
    Sylvain Rheims
    INMED INSERM U901, Universite de la Mediterranee, Marseille, France
    J Neurochem 110:1330-8. 2009
  8. ncbi Factors determining response to antiepileptic drugs in randomized controlled trials. A systematic review and meta-analysis
    Sylvain Rheims
    Hospices Civils de Lyon, Department of Functional Neurology and Epileptology, Institute for Children and Adolescents with Epilepsy IDEE, Lyon, France
    Epilepsia 52:219-33. 2011
  9. ncbi Subcontinuous epileptiform activity after failed hippocampal radiosurgery
    Sylvain Rheims
    Hospices Civils de Lyon, Department of Functional Neurology and Epileptology, Lyon, France
    Epilepsia 52:1425-9. 2011
  10. ncbi Long-term outcome of gamma-knife surgery in temporal lobe epilepsy
    Sylvain Rheims
    Department of Functional Neurology and Epileptology, Hospices Civils de Lyon, Lyon, France
    Epilepsy Res 80:23-9. 2008

Detail Information

Publications20

  1. ncbi Nocturnal hypermotor seizures, suggesting frontal lobe epilepsy, can originate in the insula
    Philippe Ryvlin
    Department of Functional Neurology and Epileptology, Hospices Civils de Lyon and Université Claude Bernard Lyon 1, Lyon, France
    Epilepsia 47:755-65. 2006
    ....
  2. ncbi Analysis of clinical patterns and underlying epileptogenic zones of hypermotor seizures
    Sylvain Rheims
    Department of Functional Neurology and Epileptology, Hospices Civils de Lyon, Lyon, France
    Epilepsia 49:2030-40. 2008
    ..Furthermore, HMS can include different forms of HM behaviors. Whether these clinical variations may be systematized and may reflect different locations of the epileptogenic zone (EZ) has not been evaluated yet...
  3. ncbi Excitatory GABA in rodent developing neocortex in vitro
    Sylvain Rheims
    Institut de Neurobiologie de la Mediterranee, Institut National de la Sante et de la Recherche Medicale U901, Universite de la Mediterranee, route de Luminy, Marseille, France
    J Neurophysiol 100:609-19. 2008
    ..In the companion paper, we show that the excitatory GABA drives layer-specific seizures in the immature neocortex...
  4. ncbi Layer-specific generation and propagation of seizures in slices of developing neocortex: role of excitatory GABAergic synapses
    Sylvain Rheims
    Institut de Neurobiologie de la Mediterranee, Institut National de la Sante et de la Recherche Medicale U901, Universite de la Mediterranee, Marseille, France
    J Neurophysiol 100:620-8. 2008
    ..In superficial layers, a persistent increase in excitability of pyramidal neurons caused by Em depolarization is associated with a transition from largely confined GABAergic IIS to ictal events that entrain the entire neocortex...
  5. ncbi Inhibitory actions of the gamma-aminobutyric acid in pediatric Sturge-Weber syndrome
    Roman Tyzio
    INMED INSERM U901, Marseille, Paris, France
    Ann Neurol 66:209-18. 2009
    ..We explored the properties of neurons from human pediatric SWS cortex in vitro and tested in particular whether gamma-aminobutyric acid (GABA) excites neurons in SWS cortex, as has been suggested for various types of epilepsies...
  6. ncbi Postnatal changes in somatic gamma-aminobutyric acid signalling in the rat hippocampus
    Roman Tyzio
    INMED INSERM U901, Universite de la Mediterranee, 163, Avenue de Luminy, 13273 Marseille, France
    Eur J Neurosci 27:2515-28. 2008
    ..Apparent hyperpolarizing GABA responses previously reported in the soma of CA3 pyramidal cells are probably due to cell depolarization during intracellular or whole-cell recordings...
  7. ncbi GABA action in immature neocortical neurons directly depends on the availability of ketone bodies
    Sylvain Rheims
    INMED INSERM U901, Universite de la Mediterranee, Marseille, France
    J Neurochem 110:1330-8. 2009
    ..Therefore, by inducing a hyperpolarizing shift in E(m) and modulating GABA signaling mode, KBs can efficiently control the excitability of neonatal cortical neurons...
  8. ncbi Factors determining response to antiepileptic drugs in randomized controlled trials. A systematic review and meta-analysis
    Sylvain Rheims
    Hospices Civils de Lyon, Department of Functional Neurology and Epileptology, Institute for Children and Adolescents with Epilepsy IDEE, Lyon, France
    Epilepsia 52:219-33. 2011
    ..However, such indirect comparisons raise various methodologic issues that may hamper their relevance...
  9. ncbi Subcontinuous epileptiform activity after failed hippocampal radiosurgery
    Sylvain Rheims
    Hospices Civils de Lyon, Department of Functional Neurology and Epileptology, Lyon, France
    Epilepsia 52:1425-9. 2011
    ....
  10. ncbi Long-term outcome of gamma-knife surgery in temporal lobe epilepsy
    Sylvain Rheims
    Department of Functional Neurology and Epileptology, Hospices Civils de Lyon, Lyon, France
    Epilepsy Res 80:23-9. 2008
    ..Either positive or negative results have been reported in studies with a maximum follow-up of 24 months. No long-term data have been published yet...
  11. ncbi Nocturnal frontal lobe epilepsy
    Philippe Ryvlin
    CTRS IDEE and Department of Functional Neurology and Epileptology, Neurological Hospital, Hospices Civiles de Lyon and Université Claude Bernard Lyon1, Lyon, France
    Epilepsia 47:83-6. 2006
    ..Further research is warranted in this field, keeping in mind that the neural networks underlying NFLE remain poorly known and might primarily involve extrafrontal brain regions in some patients...
  12. ncbi Epilepsy surgery: eligibility criteria and presurgical evaluation
    Philippe Ryvlin
    Department of Functional Neurology and Epileptology, Neurological Hospital, CTRS INSERM IDEE Institut Des Epilepsies de l Enfant et de l adolescent, Hospices Civils de Lyon, INSERM U821, Universite Claude Bernard Lyon 1, Lyon, France
    Dialogues Clin Neurosci 10:91-103. 2008
    ..The roles and specific features of the main types of presurgical investigations are reviewed...
  13. ncbi Risk of sudden unexpected death in epilepsy in patients given adjunctive antiepileptic treatment for refractory seizures: a meta-analysis of placebo-controlled randomised trials
    Philippe Ryvlin
    Department of Functional Neurology and Epileptology and Institute for Children and Adolescents with Epilepsy IDEE, Hospices Civils de Lyon, Lyon, F 69000, France
    Lancet Neurol 10:961-8. 2011
    ....
  14. ncbi Ipsilateral head deviation in frontal lobe seizures
    Sylvain Rheims
    Department of Functional Neurology and Epileptology, Neurological Hospital, Lyon, France
    Epilepsia 46:1750-3. 2005
    ..CONCLUSIONS: Ipsilateral HD is a common ictal sign during FLE and can be distinguished from contralateral HD by its time of occurrence at or immediately after seizure onset and its lacking association with clonic movements...
  15. ncbi Once-daily lamotrigine extended release for epilepsy management
    Sylvain Rheims
    Department of Functional Neurology and Epileptology, Hospices Civils de Lyon, Lyon, France
    Expert Rev Neurother 9:167-73. 2009
    ..Once-daily LTG-XR may represent a future option for patients with poor compliance to twice-daily immediate-release LTG...
  16. ncbi Greater response to placebo in children than in adults: a systematic review and meta-analysis in drug-resistant partial epilepsy
    Sylvain Rheims
    Department of Functional Neurology and Epileptology, Hospices Civils de Lyon, Lyon, France
    PLoS Med 5:e166. 2008
    ....
  17. ncbi Retigabine for partial onset seizures
    Sylvain Rheims
    Department of Functional Neurology and Epileptology and Institute for Children and Adolescent with Epilepsy, Hospices Civils de Lyon, Lyon, France
    Expert Rev Neurother 12:509-17. 2012
    ..Long-term open-label extensions of these three pivotal trials are underway. RTG has recently been approved both in Europe and in the USA for the adjunctive treatment of partial-onset seizures in adults aged 18 years and above...
  18. ncbi Peri-ictal pseudoprogression in patients with brain tumor
    Sylvain Rheims
    Service de Neuro Oncologie, Hospices Civils de Lyon, 59 Boulevard Pinel, 69003 Lyon, France
    Neuro Oncol 13:775-82. 2011
    ..This phenomenon is important to recognize in order to avoid futile therapeutic escalation...
  19. ncbi Patient and physician preferences: impact on treatment effectiveness
    Sylvain Rheims
    Department of Functional Neurology and Epileptology and Institute for Children and Adolescent with Epilepsy IDEE, Hospices Civils de Lyon, INSERM U1028, CNRS UMR5292, Lyon Neuroscience Research Center, Translational and Integrative Group in Epilepsy Research, Lyon, France
    Epileptic Disord 14:242-7. 2012
    ....
  20. ncbi Pregabalin for the management of partial epilepsy
    Philippe Ryvlin
    Service de Neurologie et d Epileptologie, Hopital Neurologique, Hospices Civils de Lyon, Universite Lyon 1, INSERM U821 and CTRS IDEE, Lyon, France
    Neuropsychiatr Dis Treat 4:1211-24. 2008
    ..During the last year on pregabalin, 3.7% of patients were seizure-free. Pregabalin appears to be a useful addition to the therapeutic armamentariun for the management of refractory partial epilepsy...