Michel Reynaud

Summary

Country: France

Publications

  1. doi Is love passion an addictive disorder?
    Michel Reynaud
    INSERM, U, Paris, France
    Am J Drug Alcohol Abuse 36:261-7. 2010
  2. doi Quantitative damage-benefit evaluation of drug effects: major discrepancies between the general population, users and experts
    Michel Reynaud
    INSERM, UMR 669, Villejuif, France
    J Psychopharmacol 27:590-9. 2013
  3. pmc Peer substance use overestimation among French university students: a cross-sectional survey
    Lionel Riou Franca
    INSERM U669 Maison de Solenn 97, bvd de Port Royal 75679 Paris Cedex 14, France
    BMC Public Health 10:169. 2010
  4. ncbi From substance dependence to addiction: impact of a conceptual shift on therapeutic approaches?
    Michel Reynaud
    Addiction Research and Treatment Center, Paul Brousse Hospital Assistance Publique Hôpitaux de Paris AP HP, 12 avenue Paul Vaillant Couturier, Villejuif, F 94800, France
    Curr Pharm Des 17:1321-2. 2011
  5. doi Dual diagnosis: prevalence, risk factors, and relationship with suicide risk in a nationwide sample of French prisoners
    Michael Lukasiewicz
    Universite Paris Sud, U669, and Universite Paris V, Paris, France
    Alcohol Clin Exp Res 33:160-8. 2009
  6. doi Heavy episodic drinking and alcohol consumption in French colleges: the role of perceived social norms
    Lionel Riou França
    From the INSERM U669, Paris, France
    Alcohol Clin Exp Res 34:164-74. 2010
  7. ncbi Is baclofen a revolutionary medication in alcohol addiction management? Review and recent updates
    Mohamed Ali Gorsane
    INSERM, U669, Paris, France
    Subst Abus 33:336-49. 2012
  8. pmc Prevalence and factors associated with alcohol and drug-related disorders in prison: a French national study
    Michael Lukasiewicz
    INSERM, U669, Paris, F 75014 France
    Subst Abuse Treat Prev Policy 2:1. 2007
  9. doi A damage/benefit evaluation of addictive product use
    Catherine Bourgain
    INSERM, Paris, France
    Addiction 107:441-50. 2012
  10. doi Association of inflammation genes with alcohol dependence/abuse: a systematic review and a meta-analysis
    Oussama Kebir
    INSERM, Laboratory of Pathophysiology of Psychiatric Diseases, Centre of Psychiatry and Neurosciences, U894, Paris, France
    Eur Addict Res 17:146-53. 2011

Collaborators

Detail Information

Publications42

  1. doi Is love passion an addictive disorder?
    Michel Reynaud
    INSERM, U, Paris, France
    Am J Drug Alcohol Abuse 36:261-7. 2010
    ..Inquiry regarding the relationship between passionate love and addiction has long been a topic of intense debate. Recent advances in neurobiology now allow for an examination between these two states...
  2. doi Quantitative damage-benefit evaluation of drug effects: major discrepancies between the general population, users and experts
    Michel Reynaud
    INSERM, UMR 669, Villejuif, France
    J Psychopharmacol 27:590-9. 2013
    ..We compared with expert assessments and investigated the effects of substance consumption on these perceptions...
  3. pmc Peer substance use overestimation among French university students: a cross-sectional survey
    Lionel Riou Franca
    INSERM U669 Maison de Solenn 97, bvd de Port Royal 75679 Paris Cedex 14, France
    BMC Public Health 10:169. 2010
    ..There is less research on other substances or European cultural contexts. This study explores which factors are associated with alcohol, tobacco and cannabis use misperceptions among French college students, focusing on substance use...
  4. ncbi From substance dependence to addiction: impact of a conceptual shift on therapeutic approaches?
    Michel Reynaud
    Addiction Research and Treatment Center, Paul Brousse Hospital Assistance Publique Hôpitaux de Paris AP HP, 12 avenue Paul Vaillant Couturier, Villejuif, F 94800, France
    Curr Pharm Des 17:1321-2. 2011
    ..This conceptual shift seems to enrich clinical analysis, the therapeutic possibilities and the avenues for research...
  5. doi Dual diagnosis: prevalence, risk factors, and relationship with suicide risk in a nationwide sample of French prisoners
    Michael Lukasiewicz
    Universite Paris Sud, U669, and Universite Paris V, Paris, France
    Alcohol Clin Exp Res 33:160-8. 2009
    ..Dual diagnosis (DD) (the co-occurrence of a SUD and any axis I disorder) is known to have a poorer prognosis and to require more intense supportive care...
  6. doi Heavy episodic drinking and alcohol consumption in French colleges: the role of perceived social norms
    Lionel Riou França
    From the INSERM U669, Paris, France
    Alcohol Clin Exp Res 34:164-74. 2010
    ..The objective of this study is therefore to assess whether social norms of alcohol use are related to HED in France, taking account of other influential predictors...
  7. ncbi Is baclofen a revolutionary medication in alcohol addiction management? Review and recent updates
    Mohamed Ali Gorsane
    INSERM, U669, Paris, France
    Subst Abus 33:336-49. 2012
    ..Thus, baclofen should benefit from further studies of its biobehavioral mechanisms, dose-response effect, and indications in various alcoholic patient profiles...
  8. pmc Prevalence and factors associated with alcohol and drug-related disorders in prison: a French national study
    Michael Lukasiewicz
    INSERM, U669, Paris, F 75014 France
    Subst Abuse Treat Prev Policy 2:1. 2007
    ..At the end of the interview the clinicians met and agreed on a list of diagnoses. Cloninger's Temperament and Character Inventory (TCI) was also used...
  9. doi A damage/benefit evaluation of addictive product use
    Catherine Bourgain
    INSERM, Paris, France
    Addiction 107:441-50. 2012
    ..To obtain damage/benefit assessments of eight commonly used addictive products and one addictive behaviour from French addiction experts and link these to overall evaluations...
  10. doi Association of inflammation genes with alcohol dependence/abuse: a systematic review and a meta-analysis
    Oussama Kebir
    INSERM, Laboratory of Pathophysiology of Psychiatric Diseases, Centre of Psychiatry and Neurosciences, U894, Paris, France
    Eur Addict Res 17:146-53. 2011
    ..Our approach is limited by our phenotype definition; some studies included chronic heavy drinkers (minimal daily consumption of 80 g for a minimal duration of 10 years) but without a standardized psychiatric assessment...
  11. doi CNR1 gene polymorphisms in addictive disorders: a systematic review and a meta-analysis
    Amine Benyamina
    INSERM U, Paris, France
    Addict Biol 16:1-6. 2011
    ..Further studies in well-phenotyped samples and using more polymorphisms are needed to conclude on the actual influence of cannabinoid receptor polymorphisms...
  12. doi [Addiction to cocaine: a risk factor for suicide?]
    Aymeric Petit
    Hopital Bichat Claude Bernard, 46 rue Henri Huchard, Paris, France
    Presse Med 41:702-12. 2012
    ....
  13. doi Striatal and extrastriatal dopamine transporter in cannabis and tobacco addiction: a high-resolution PET study
    Claire Leroy
    INSERM U1000 Research Unit Neuroimaging and Psychiatry, IFR49, Orsay, France
    Addict Biol 17:981-90. 2012
    ..These findings are consistent with the idea of a global decrease in cerebral DA activity in dependent subjects...
  14. pmc Pharmacological approaches to methamphetamine dependence: a focused review
    Laurent Karila
    Addiction Research and Treatment Center, Paul Brousse Hospital, Paris XI University, AP HP, CEA INSERM U1000, Villejuif, France
    Br J Clin Pharmacol 69:578-92. 2010
    ..Despite the lack of success in most studies to date, increasing efforts are being made to develop medications for the treatment of methamphetamine dependence and several promising agents are targets of further research...
  15. doi Diffusion tensor tractography in mesencephalic bundles: relation to mental flexibility in detoxified alcohol-dependent subjects
    Sandra Chanraud
    INSERM, U797 Research Unit Neuroimaging and Psychiatry, IFR49, Orsay, France
    Neuropsychopharmacology 34:1223-32. 2009
    ....
  16. ncbi Acute and long-term effects of cannabis use: a review
    Laurent Karila
    Addiction Research and Treatment Center, Paul Brousse Hospital, 12 avenue Paul Vaillant Couturier, Villejuif 94800, France
    Curr Pharm Des 20:4112-8. 2014
    ....
  17. ncbi Sexual addiction or hypersexual disorder: different terms for the same problem? A review of the literature
    Laurent Karila
    Addiction Research and Treatment Center, Paul Brousse Hospital, 12 avenue Paul Vaillant Couturier, Villejuif 94800, France
    Curr Pharm Des 20:4012-20. 2014
    ..Psychiatric and somatic comorbidities that frequently occur with sexual addiction should be integrated into the therapeutic process. Group-based treatments should also be attempted. ..
  18. pmc Are social norms associated with smoking in French university students? A survey report on smoking correlates
    Lionel Riou Franca
    INSERM U669, Maison de Solenn 97, bvd de Port Royal, 75679, Paris, Cedex 14, France
    Subst Abuse Treat Prev Policy 4:4. 2009
    ..This study was designed to test the theory that smoking is associated with perceived norms, controlling for other correlates of smoking...
  19. ncbi Pharmacological treatments for cocaine dependence: is there something new?
    Laurent Karila
    Addiction Research and Treatment Center, Paul Brousse Hospital Assistance Publique Hôpitaux de Paris AP HP, Villejuif, France
    Curr Pharm Des 17:1359-68. 2011
    ..Therefore, developing new medications for the treatment of this disease continues to be a research priority. Recent advances in neurobiology and brain imaging studies have suggested several promising pharmacological approaches...
  20. ncbi Pharmacological treatments of opiate dependence
    Amine Benyamina
    INSERM U669, Paris, France
    Curr Pharm Des 17:1384-8. 2011
    ..The objective of this article is to examine the evidence concerning the treatment of opiate dependent patients, especially new treatments and to examine the eventual gaps between currently knowledge, available treatment and demands...
  21. pmc Episodic memory in detoxified alcoholics: contribution of grey matter microstructure alteration
    Sandra Chanraud
    INSERM, U797 Research Unit Neuroimaging and Psychiatry, IFR49, Orsay, France
    PLoS ONE 4:e6786. 2009
    ..These findings support the hypothesis that regional microstructural but no macrostructural alteration of the brain might be responsible, at least in part, for episodic memory deficits in alcohol dependence...
  22. doi Association between MTHFR 677C-T polymorphism and alcohol dependence according to Lesch and Babor typology
    Amine Benyamina
    Service d Addictologie, Hopital Paul Brousse, Paul Vaillant Couturier, Villejuif Cedex, Assistance Publique Hopitaux de Paris, France
    Addict Biol 14:503-5. 2009
    ..MTHFR TT was also associated with hyperhomocysteinemia. Determining MTHFR 677C-T genotype, folate and vitamin B12 levels could assist physicians in identifying type 3 patients and improve addictions management...
  23. ncbi [Therapeutic approaches to cocaine addiction]
    Laurent Karila
    Centre d enseignement, de Recherche et de Traitement des Addictions, Hôpital Universitaire Paul Brousse, AP HP, INSERM U669, Universite Paris XI, 94804 Villejuif Cedex
    Rev Prat 59:830-4. 2009
    ..Partial agonists at the dopamine D2 receptor and anticocaine vaccines are other promising treatment approaches. It is important to clearly differentiate the detoxification treatment and the relapse prevention treatment phases...
  24. ncbi [Current pharmacotherapies and immunotherapy in cocaine addiction]
    Laurent Karila
    Universite Paris Sud, F 94276 Le Kremlin Bicetre, France
    Presse Med 37:689-98. 2008
    ..However, this must be confirmed in larger patient populations...
  25. doi Disposition of Delta tetrahydrocannabinol in CF1 mice deficient in mdr1a P-glycoprotein
    Laurence Bonhomme-Faivre
    Department of Pharmacology and Pharmacy, Hopital Paul Brousse, 14 avenue Paul Vaillant Couturier, 94800 Villejuif, France
    Addict Biol 13:295-300. 2008
    ..We concluded that P-gp limits THC oral uptake and mediates direct drug excretion from the systemic circulation into the intestinal lumen...
  26. ncbi [Cocaine: from recreational use to dependence]
    Laurent Karila
    Centre d enseignement, de Recherche et de Traitement des Addictions, Hôpital Universitaire Paul Brousse, AP HP, CEA Inserm U797, Universite Paris XI, 94804 Villejuif Cedex
    Rev Prat 59:821-5. 2009
    ....
  27. doi Pharmacotherapy and psychotherapy in cannabis withdrawal and dependence
    Amine Benyamina
    Centre d enseignement, de Recherche et de Traitement des Addictions, Hopital Paul Brousse, 94804 Villejuif Cedex, France
    Expert Rev Neurother 8:479-91. 2008
    ..For the moment, it is uncertain whether the additional treatment costs associated with voucher incentives are proportional to the accrued abstinence duration...
  28. ncbi Pharmacotherapy for smoking cessation: present and future
    Henri Jean Aubin
    Substance Abuse Treatment Center, Hopital Paul Brousse, Hôpitaux Universitaires Paris Sud, AP HP, INSERM U 669 UniversityParis Sud, 12 Avenue Paul Vaillant Couturier 94800 Villejuif, France
    Curr Pharm Des 17:1343-50. 2011
    ..Clonidine and nortriptyline have been proposed as second-line medications. In addition, this review indentifies a series of promising drugs that hopefully will be available to complete our current armory...
  29. ncbi [Drug addiction and addictive behavior. Part 2 - alcohol, psychoactive and illicit substances]
    Laurent Karila
    Universite Paris Sud, Le Kremlin Bicetre, F 94276, France
    Rev Prat 58:1131-40; quiz 1149. 2008
  30. ncbi [Complications of cocaine addiction]
    Laurent Karila
    Clinique Montevideo, 92100 Boulogne Billancourt
    Rev Prat 59:825-9. 2009
    ..Psychiatric complications found in clinical practice are major depressive disorders, cocaine-induced paranoia, cocaine-induced compulsive foraging and panic attacks...
  31. ncbi Excessive indoor tanning as a behavioral addiction: a literature review
    Aymeric Petit
    Department of Psychiatry and Addictive Medicine, Bichat Claude Bernard Hospital, AP HP, Paris, France
    Curr Pharm Des 20:4070-5. 2014
    ..Further controlled studies must be performed, especially in neurobiology and imaging, to improve our understanding of tanning dependence. ..
  32. doi [Cognitive modifications associated with tobacco smoking]
    Marie Lecacheux
    Universite Paris Sud, Le Kremlin Bicetre, INSERM U669, Paris, Hopital Paul Brousse, Villejuif, France
    Presse Med 38:1241-52. 2009
    ..It is associated with cognitive disorders which tend to maintain addictive mechanisms. In the short term, the nicotine contained in tobacco enhances attention and memory...
  33. doi Association between a polymorphism in the promoter of a glutamate receptor subunit gene (GRIN2A) and alcoholism
    Marie Charlotte Domart
    Laboratoire de Biochimie et Biologie Moleculaire, AP HP, Hopital Paul Brousse, Universite Paris, INSERM U, IFR Villejuif, France
    Addict Biol 17:783-5. 2012
    ..58, P-value = 7 × 10(-4)). These results could be replicated in an independent sample of 116 alcohol-dependent subjects. For the first time, a significant association was identified between this polymorphism and alcoholism...
  34. doi Association between ABCB1 C3435T polymorphism and increased risk of cannabis dependence
    Amine Benyamina
    INSERM, U669, Paris, France
    Prog Neuropsychopharmacol Biol Psychiatry 33:1270-4. 2009
    ..ABCB1 polymorphisms may alter Delta9THC distribution, its psychoactive effects and individual vulnerability to dependence. These results pave the way to a new pharmacogenetic hypothesis in cannabis dependence...
  35. pmc Impact of practitioner's training in the management of alcohol dependence: a quasi-experimental 18-month follow-up study
    Laurent Malet
    CHU Clermont Ferrand, Clermont Ferrand, F 63000, France INSERM, U669, Paris, F 75014, France
    Subst Abuse Treat Prev Policy 1:18. 2006
    ..Our purpose was to assess the impact of a multifaceted intervention by trained GPs in the management of alcohol-dependent patients...
  36. doi Pathways to substance-related disorder: a structural model approach exploring the influence of temperament, character, and childhood adversity in a national cohort of prisoners
    Michael Lukasiewicz
    INSERM, U669, Paris, F 75014 France
    Alcohol Alcohol 43:287-95. 2008
    ....
  37. ncbi New treatments for cocaine dependence: a focused review
    Laurent Karila
    INSERM, U797, Hospital Department Frederic Joliot, 12BM, Orsay, France
    Int J Neuropsychopharmacol 11:425-38. 2008
    ..An anti-cocaine vaccine and several compounds in preclinical development have also shown promise. Findings from early clinical trials must be confirmed in larger, less selective patient populations...
  38. ncbi Cannabis arteritis: review of the literature
    Olivier Cottencin
    From the Departments of Addictology OC, MG and Internal Medicine ML, University Hospital of Lille, Lille and Department of Addictology LK, CA, A Benyamina, A Boissonas, Paul Brousse University Hospital, Villejuif, France
    J Addict Med 4:191-6. 2010
    ..Cannabis consumption would however seems to be an aggravating factor, together with tobacco, in arteritis, which occurs in young adults...
  39. ncbi Clinical determinants of cognition levels in French cocaine addicted patients
    Michael Szprync
    Addictology Department 200 rue du faubourg Saint Denis, Paris, France
    Curr Pharm Des 20:4086-96. 2014
    ..In the CCU group, exposure to cocaine seemed to have a negative impact on cognition especially inhibitory control, memory and impulsivity. In the abstainers group, craving and depression impeded cognition. ..
  40. ncbi Reports on defense styles in depression
    Marie Bronnec
    Department of Psychiatry, Bicetre Hospital, Assistance Publique Hopitaux de Paris, Le Kremlin Bicetre, Paris, France
    Psychopathology 38:9-15. 2005
    ..Our hypothesis was that an informant could assess the defensive functioning of the depressed patient. The objective of this study was to investigate the validity of the informants' assessment of defense styles in depressed patients...
  41. ncbi Predictive factors of the number and the dose of anti-psychotics in a cohort of schizophrenic patients
    Michael Lukasiewicz
    INSERM unit 669, Universite Paris XI, AP HP, Maison de Solenn, 97 Boulevard de Port Royal, Paris, France
    Pharmacoepidemiol Drug Saf 15:594-601. 2006
    ..Anti-psychotic prescription in schizophrenia is characterised in Europe by frequent associations and high doses. Nevertheless, few longitudinal epidemiological studies have explored anti-psychotic prescriptions...
  42. ncbi Defense styles, impulsivity and suicide attempts in major depression
    Emmanuelle Corruble
    Psychiatry Department, Bicetre Hospital, Assistance Publique, Hopitaux de Paris, Paris XI University, Le Kremlin Bicetre, Paris, France
    Psychopathology 36:279-84. 2003
    ..The aim of our study was to identify if defense mechanisms are associated with impulsivity and lifetime suicide attempts in depressed patients...