- Stem cell factor expression, mast cells and inflammation in asthmaCarla A Da Silva
EA3771, Inflammation and Environment in Asthma, , BP 24, 67401 Illkirch Cedex, France
Fundam Clin Pharmacol 20:21-39. 2006..We here report the main pathways of SCF synthesis and signalling, and its potential role on airway function and asthma...
- Stem cell factor and its receptor c-Kit as targets for inflammatory diseasesLaurent Reber
EA 3771 Inflammation and Environment in Asthma, Université Louis Pasteur Strasbourg I, Faculte de Pharmacie, Illkirch, France
Eur J Pharmacol 533:327-40. 2006..Taken together, these data suggest that SCF/c-Kit may be a potential therapeutic target for the control of mast cell and eosinophil number and activation in inflammatory diseases...
- Ser276 phosphorylation of NF-kB p65 by MSK1 controls SCF expression in inflammationLaurent Reber
EA3771, Inflammation and Environment in Asthma, Université Louis Pasteur Strasbourg I, Faculte de Pharmacie, Illkirch, France
PLoS ONE 4:e4393. 2009..Our study provides therefore a direct link between MSK1-mediated phosphorylation of Ser276 p65 of NF-kappaB, allowing its binding to the SCF intronic enhancer, and pathophysiological SCF expression in inflammation...