- [Application of the causal theory of action through analysis of therapeutic non-observance]G Reach
INSERM U341, Service de Diabetologie, Hotel Dieu, 1, Place du Parvis Notre Dame, F75181 Paris
Presse Med 29:1939-46. 2000..The problem is analysed through the causal theory of action and the concept of akrasia. These considerations may be useful to understand other aspects of therapeutic non-observance...
- Two character traits associated with adherence to long term therapiesGerard Reach
Department of Endocrinology Diabetology Metabolic Diseases, Hospital Avicenne APHP and EA 3412, CRNH IdF, University Paris 13, Bobigny, France
Diabetes Res Clin Pract 98:19-25. 2012..Thus, one of the roles of empowerment and patient education could be to encourage the patients, if they wish it, to replace passive adherence behaviours with conscious active choices...
- Role of habit in adherence to medical treatmentG Reach
Service de Médecine Interne et Endocrinologie, Hopital Avicenne, Assistance Publique Hopitaux de Paris, Bobigny, France
Diabet Med 22:415-20. 2005..By clarifying the notions of intention and decision, this novel analysis may be useful for understanding the dynamics of diabetes care...
- Observance in diabetes: from therapeutic education to therapeutic allianceGerard Reach
Service de Médecine Interne et Endocrinologie, Hopital Avicenne, Assistance Publique Hopitaux de Paris, 93009 Bobigny
Ann Med Interne (Paris) 154:117-20. 2003..This will lead us to clarify the relationship between therapeutic education and observance, and to justify on a theoretical basis the concept of therapeutic alliance...
- Adjusting insulin doses: from knowledge to decisionGerard Reach
INSERM U341, Service de Diabetologie, Hotel Dieu, Paris, and Service de Médecine Interne et Endocrinologie, Hopital Avicenne, Assistance Publique Hopitaux de Paris, 125 route de Stalingrad, 93000 Bobigny, France
Patient Educ Couns 56:98-103. 2005..It also shows that the degree of confidence in one's own knowledge, the health beliefs, and the fear of hypoglycemia differently influence the perception that the patients have of their behavior, and what they really do...
- [Can patient compliance be improved?]Gerard Reach
Service de médecine interne endocrinologie Hôpital Avicenne 93009 Bobigny
Rev Prat 53:1109-12. 2003....
- eNOS4 polymorphism of the endothelial nitric oxide synthase predicts risk for severe diabetic retinopathyM J Taverna
INSERM U 341, Department of Diabetology and Ophthalmo Diabetology Unit, Hotel Dieu Hospital, Paris, France
Diabet Med 19:240-5. 2002..Increased nitric oxide generation has been suggested to play a significant role in the pathogenesis of DR...
- Calibration of a subcutaneous amperometric glucose sensor implanted for 7 days in diabetic patients. Part 2. Superiority of the one-point calibration methodC Choleau
INSERM U341, Diabetes Department, Hotel Dieu Hospital, 1 Place du Parvis Notre Dame, 75004, Paris, France
Biosens Bioelectron 17:647-54. 2002..e. the transformation in real time of the signal I(t) generated by the glucose sensor at time t into an estimation of glucose concentration G(t), represents a key issue for the development of a continuous glucose monitoring system...
- A user-friendly method for calibrating a subcutaneous glucose sensor-based hypoglycaemic alarmB Aussedat
INSERM U 341, Department of Diabetology, , Paris, France
Biosens Bioelectron 12:1061-71. 1997....
- Inhibition of insulin secretion by leptin in normal rodent islets of LangerhansV Poitout
INSERM U341, Service de Diabetologie, Paris, France
Endocrinology 139:822-6. 1998..These results suggest that, in normal rodent islets, leptin specifically inhibits IBMX-potentiated glucose-induced insulin secretion, through a direct effect involving at least one of the three isoforms of OB-R expressed in islets...
- Calibration in dogs of a subcutaneous miniaturized glucose sensor using a glucose meter for blood glucose determinationV Poitout
INSERM U341, , , Paris, France
Biosens Bioelectron 7:587-92. 1992..82, p = 0.45, n.s.). (3) The regression equation of the estimation of the subcutaneous glucose level obtained from the two methods was y = 1.04x + 0.56 mM (n = 171 values, r = 0.98, p = 0.0001).(ABSTRACT TRUNCATED AT 250 WORDS)..
- [Possible consequences on the follow up of type 2 diabetic patients of a recent modification of a glycosylated hemoglobin assay]G Reach
Service de Diabetologie, Hotel Dieu, Paris
Diabetes Metab 25:432-5. 1999..5% for a 8% value. Such is no more the case...
- Patients' impatience is an independent determinant of poor diabetes controlG Reach
Department of Endocrinology, Diabetes and Metabolic Diseases, Avicenne Hospital, AP HP, University Paris 13, 93009 Bobigny Cedex, France
Diabetes Metab 37:497-504. 2011..Some individuals have a preference for the present rather than for the future. We investigated the impact of this impatient relationship to temporality on adherence to medication and HbA(1c) level in type 2 diabetic patients...
- Accuracy of the continuous glucose monitoring system in inpatient and outpatient conditionsC Djakouré-Platonoff
Service de Diabetologie, Hotel Dieu, Paris, France
Diabetes Metab 29:159-62. 2003..To evaluate in inpatient and outpatient conditions, using only non-calibration data, the accuracy of the Continuous Glucose Monitoring System (CG-MS)...
- Evaluating in vitro and in vivo the interference of ascorbate and acetaminophen on glucose detection by a needle-type glucose sensorD Moatti Sirat
INSERM U 341, , , Paris, France
Biosens Bioelectron 7:345-52. 1992..Using the current generated in the presence of a plasma acetaminophen concentration of about 200 mumol l-1 for glucose monitoring would lead to a major underestimation (approx. 6 mmol l-1) of subcutaneous glucose concentrations...
- [Towards a cell therapy for diabetes? An epistemiological perspective]G Reach
INSERM U341, Service de Diabetologie, Hotel Dieu, 1, Place du Parvis Notre Dame, 75404 Paris
J Soc Biol 195:83-90. 2001..This text tries to delineate some factors which may be involved in the chances for these techniques to reach the real world of human therapeutics...
- Linguistic barriers in diabetes careG Reach
Service d endocrinologie diabétologie maladies métaboliques, Hôpital Avicenne APHP, 93000 Bobigny, France
Diabetologia 52:1461-3. 2009..Linguistic barriers can pose major problems. Patient education needs to avoid jargon, and when introducing a new concept to the patient, the healthcare provider needs to check that it is understood...
- Benefits of Ophdiat, a telemedical network to screen for diabetic retinopathy: a retrospective study in five reference hospital centresA Chabouis
Assistance Publique Hopitaux de Paris, Paris, France
Diabetes Metab 35:228-32. 2009..The aim of this study was to evaluate the benefits of this programme in a hospital setting...
- High day-to-day glucose variability: a frequent phenomenon in children and adolescents with type 1 diabetes attending summer campC Choleau
Service d endocrinologie, diabétologie et maladies métaboliques, Hopital Avicenne, AP HP, and CRNH IdF, EA 3412, Universite Paris 13, 125, route de Stalingrad, 93000 Bobigny, France
Diabetes Metab 34:46-51. 2008..The aim of this research was to evaluate the frequency of high variability in a population of diabetic children and adolescents attending summer camp...
- Calibration of a subcutaneous amperometric glucose sensor. Part 1. Effect of measurement uncertainties on the determination of sensor sensitivity and background currentC Choleau
INSERM U341, Diabetes Department, Hotel Dieu Hospital, 1, Place du Parvis Notre Dame, 75004, Paris, France
Biosens Bioelectron 17:641-6. 2002..Theoretical analysis demonstrates that this phenomenon can be explained by the effect of measurement uncertainties on the determination of capillary glucose concentration and of sensor output...
- [Continuous glucose monitoring: different systems, different ambitions]C Choleau
INSERIM U341, Service de Diabétique, Hotel Dieu, Paris, France
Diabetes Metab 29:S15-20. 2003....
- Patient non-adherence and healthcare-provider inertia are clinical myopiaG Reach
Department of Endocrinology, Diabetes and Metabolic Diseases, Avicenne Hospital, AP HP and Laboratory of Pedagogy of Health, EA 3412, University Paris 13, CRNH IdF, Bobigny, France
Diabetes Metab 34:382-5. 2008..We dub such a failure as "clinical myopia". The model is explained in the context of clinical observations made in type 1 and 2 diabetic patients. However, it may also be relevant to other asymptomatic chronic diseases...
- Limbic encephalitis and type 1 diabetes with glutamic acid decarboxylase 65 (GAD65) autoimmunity: improvement with high-dose intravenous immunoglobulin therapyM Lopez-Sublet
Post Emergency Unit, Department of Internal Medicine, Hopital Avicenne, 125, route de Stalingrad, 93009 Bobigny Cedex, France
Diabetes Metab 38:273-5. 2012..This report is of a patient with type 1 diabetes and a rare case of non-paraneoplastic limbic encephalitis mediated by anti-GAD65 antibodies that improved with the use of immunosuppressive drugs...
- PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistanceM Guerre-Millo
Unit 465, Institut National de la Sante et de la Recherche Medicale INSERM, Paris, France
Diabetes 50:2809-14. 2001..These data suggest that PPAR-alpha plays a role for the development of IR in response to a Western-type high-fat diet...
- Taq I polymorphism of the vitamin D receptor and risk of severe diabetic retinopathyM J Taverna
INSERM U341, Hotel Dieu Hospital, Paris, France
Diabetologia 45:436-42. 2002..We examined whether Taq I polymorphism of the vitamin D receptor is involved in the development of severe diabetic retinopathy...
- Innovative therapies: some ethical considerationsG Reach
Department of Endocrinology, Diabetes and Metabolic Diseases, Avicenne Hospital, APHP, Bobigny, France
Diabetes Metab 32:527-31. 2006..We shall show how they can guide the ethical inquiry in the field of pancreas or islet transplantation, leading to an analysis of the risks and benefits of the innovations epistemologically taking into account their historical context...