Philippe Ravaud

Summary

Country: France

Publications

  1. ncbi request reprint Primer: assessing the efficacy and safety of nonpharmacologic treatments for chronic rheumatic diseases
    Philippe Ravaud
    University of Paris VII, Paris, France
    Nat Clin Pract Rheumatol 2:313-9. 2006
  2. pmc Reporting of harm in randomized controlled trials evaluating stents for percutaneous coronary intervention
    Morgane Ethgen
    INSERM, U738, Paris, F 75018 France
    Trials 10:29. 2009
  3. pmc Effect of response format for clinical vignettes on reporting quality of physician practice
    Thao Pham
    Department of Rheumatology, CHU Conception, 13005 Marseille, France
    BMC Health Serv Res 9:128. 2009
  4. pmc Knee arthroplasty: disabilities in comparison to the general population and to hip arthroplasty using a French national longitudinal survey
    Agnes Dechartres
    INSERM, U738, Paris, France
    PLoS ONE 3:e2561. 2008
  5. pmc Clinical and biological assessment of cemented titanium femoral stems: an 11-year experience
    Patrick Boyer
    Department of Orthopaedic and Trauma Surgery, Bichat Hospital, 46 rue Henri Huchard, 75018, Paris, France
    Int Orthop 33:1209-15. 2009
  6. doi request reprint Do case vignettes accurately reflect antibiotic prescription?
    Jean Christophe Lucet
    Infection Control Unit, Bichat Claude Bernard Hospital, Assistance Publique Hopitaux de Paris, Paris, and Université Paris Diderot, Sorbonne Paris Cité, France
    Infect Control Hosp Epidemiol 32:1003-9. 2011
  7. ncbi request reprint Actual management of patients with asymptomatic aortic valve disease: how practice fits with guidelines
    Bernard Iung
    Cardiology Department, Bichat Hospital, AP HP, Paris, France
    Am Heart J 153:696-703. 2007
  8. ncbi request reprint Evolution of disability in adults with hip arthroplasty: a national longitudinal study
    Agnes Dechartres
    INSERM, U738, Universite Paris 7, UFR de Medecine, AP HP Hôpital Bichat, Département d Epidémiologie, Biostatistique et Recherche Clinique, Paris, France
    Arthritis Rheum 57:364-71. 2007
  9. doi request reprint The variability in minimal clinically important difference and patient acceptable symptomatic state values did not have an impact on treatment effect estimates
    Florence Tubach
    AP HP, Hopital Bichat, Département d Epidémiologie, Biostatistique et Recherche Clinique, Paris, France
    J Clin Epidemiol 62:725-8. 2009
  10. ncbi request reprint Extending the CONSORT statement to randomized trials of nonpharmacologic treatment: explanation and elaboration
    Isabelle Boutron
    INSERM U738, AP HP, Hopital Bichat Claude Bernard, and Université Paris 7 Denis Diderot, Paris, France
    Ann Intern Med 148:295-309. 2008

Detail Information

Publications121 found, 100 shown here

  1. ncbi request reprint Primer: assessing the efficacy and safety of nonpharmacologic treatments for chronic rheumatic diseases
    Philippe Ravaud
    University of Paris VII, Paris, France
    Nat Clin Pract Rheumatol 2:313-9. 2006
    ....
  2. pmc Reporting of harm in randomized controlled trials evaluating stents for percutaneous coronary intervention
    Morgane Ethgen
    INSERM, U738, Paris, F 75018 France
    Trials 10:29. 2009
    ..The aim of this study was to assess the reporting of harm in randomized controlled trials evaluating stents for percutaneous coronary intervention...
  3. pmc Effect of response format for clinical vignettes on reporting quality of physician practice
    Thao Pham
    Department of Rheumatology, CHU Conception, 13005 Marseille, France
    BMC Health Serv Res 9:128. 2009
    ....
  4. pmc Knee arthroplasty: disabilities in comparison to the general population and to hip arthroplasty using a French national longitudinal survey
    Agnes Dechartres
    INSERM, U738, Paris, France
    PLoS ONE 3:e2561. 2008
    ..A secondary objective was to compare the level of disabilities of people with knee to people with hip arthroplasty...
  5. pmc Clinical and biological assessment of cemented titanium femoral stems: an 11-year experience
    Patrick Boyer
    Department of Orthopaedic and Trauma Surgery, Bichat Hospital, 46 rue Henri Huchard, 75018, Paris, France
    Int Orthop 33:1209-15. 2009
    ..The protective layer of titanium oxide coating the stem and a thick cement mantle may help resist aseptic loosening. In addition, satisfactory monitoring of the stem was reached using titanium serum level determination...
  6. doi request reprint Do case vignettes accurately reflect antibiotic prescription?
    Jean Christophe Lucet
    Infection Control Unit, Bichat Claude Bernard Hospital, Assistance Publique Hopitaux de Paris, Paris, and Université Paris Diderot, Sorbonne Paris Cité, France
    Infect Control Hosp Epidemiol 32:1003-9. 2011
    ..Antibiotic prescription is frequently inappropriate in hospitals. Our objective was to evaluate whether the quality of antibiotic prescription could be measured using case vignettes to assess physicians' knowledge...
  7. ncbi request reprint Actual management of patients with asymptomatic aortic valve disease: how practice fits with guidelines
    Bernard Iung
    Cardiology Department, Bichat Hospital, AP HP, Paris, France
    Am Heart J 153:696-703. 2007
    ..Intervention is advised in selected asymptomatic patients with aortic valve disease. However, little is known regarding their actual management...
  8. ncbi request reprint Evolution of disability in adults with hip arthroplasty: a national longitudinal study
    Agnes Dechartres
    INSERM, U738, Universite Paris 7, UFR de Medecine, AP HP Hôpital Bichat, Département d Epidémiologie, Biostatistique et Recherche Clinique, Paris, France
    Arthritis Rheum 57:364-71. 2007
    ..To describe disability in individuals with hip arthroplasty and its evolution over 2 years compared with that in the general population, and to compare the degree of disability between subjects with recent and older hip arthroplasty...
  9. doi request reprint The variability in minimal clinically important difference and patient acceptable symptomatic state values did not have an impact on treatment effect estimates
    Florence Tubach
    AP HP, Hopital Bichat, Département d Epidémiologie, Biostatistique et Recherche Clinique, Paris, France
    J Clin Epidemiol 62:725-8. 2009
    ..The objective was to investigate the influence of the choice of MCID and/or PASS values on the difference in success rate between arms...
  10. ncbi request reprint Extending the CONSORT statement to randomized trials of nonpharmacologic treatment: explanation and elaboration
    Isabelle Boutron
    INSERM U738, AP HP, Hopital Bichat Claude Bernard, and Université Paris 7 Denis Diderot, Paris, France
    Ann Intern Med 148:295-309. 2008
    ..This extension, in conjunction with the main CONSORT Statement and other CONSORT extensions, should help to improve the reporting of RCTs performed in this field...
  11. ncbi request reprint Validation of a short form of the Western Ontario and McMaster Universities Osteoarthritis Index function subscale in hip and knee osteoarthritis
    Gabriel Baron
    AP HP, Hopital Bichat, Département d Eidémiologie, Biostatistique et Recherche Clinique, INSERM, U738, Paris, France
    Arthritis Rheum 57:633-8. 2007
    ..The goal of the present study was to validate this short form...
  12. pmc Planning a cluster randomized trial with unequal cluster sizes: practical issues involving continuous outcomes
    Lydia Guittet
    Département d Epidémiologie, Biostatistique et Recherche Clinique, Groupe Hospitalier Bichat Claude Bernard AP HP, Université Xavier Bichat, Paris, France
    BMC Med Res Methodol 6:17. 2006
    ..At the planning stage, sample size calculations usually consider an average cluster size without taking into account any potential imbalance in cluster size. However, there may exist high discrepancies in cluster sizes...
  13. ncbi request reprint Splint for base-of-thumb osteoarthritis: a randomized trial
    Francois Rannou
    Assistance Publique Hopitaux de Paris, Hopital Cochin, Paris, France
    Ann Intern Med 150:661-9. 2009
    ..Some guidelines recommend splinting for base-of-thumb osteoarthritis, despite lack of evidence of efficacy...
  14. doi request reprint Survival after bilateral versus single-lung transplantation for idiopathic pulmonary fibrosis
    Gabriel Thabut
    Hopital Bichat, APHP et Université Paris Diderot Paris 7, INSERM U738, Inserm U717, Paris, France
    Ann Intern Med 151:767-74. 2009
    ..Patients with end-stage idiopathic pulmonary fibrosis (IPF) are increasingly having bilateral rather than single-lung transplantation...
  15. pmc Misrepresentation of randomized controlled trials in press releases and news coverage: a cohort study
    Amélie Yavchitz
    INSERM, U738, Paris, France
    PLoS Med 9:e1001308. 2012
    ..We aimed to (1) evaluate the presence of "spin" in press releases and associated media coverage; and (2) evaluate whether findings of randomized controlled trials (RCTs) based on press releases and media coverage are misinterpreted...
  16. doi request reprint Effect of adherence to European treatment recommendations on early arthritis outcome: data from the ESPOIR cohort
    Cécile Escalas
    INSERM U738, Paris, France
    Ann Rheum Dis 71:1803-8. 2012
    ..To assess the association of adherence to the 2007 recommendations of the European League Against Rheumatism (EULAR) for managing early arthritis and radiographic progression and disability in patients..
  17. pmc Geographical representativeness of published and ongoing randomized controlled trials. The example of: Tobacco consumption and HIV infection
    Nizar Ahmad
    INSERM, U738, Paris, France
    PLoS ONE 6:e16878. 2011
    ..This study aimed to compare where research is conducted to where research is needed for 2 public health priorities: tobacco consumption and HIV infection...
  18. ncbi request reprint Stability of the patient acceptable symptomatic state over time in outcome criteria in ankylosing spondylitis
    Florence Tubach
    Assistance Publique Hopitaux de Paris, Bichat Hospital, University Paris VII, INSERM U738, Paris, France
    Arthritis Rheum 55:960-3. 2006
    ..Our goal was to determine the PASS in main outcome criteria when assessing patients with ankylosing spondylitis (AS) and to evaluate whether the PASS is stable over time...
  19. pmc Reporting methods of blinding in randomized trials assessing nonpharmacological treatments
    Isabelle Boutron
    INSERM, U738, Paris, France
    PLoS Med 4:e61. 2007
    ..The purpose of this study was to systematically describe the strategies used to obtain blinding in a sample of randomized controlled trials of nonpharmacological treatment...
  20. ncbi request reprint Feeling good rather than feeling better matters more to patients
    Florence Tubach
    Assistance Publique Hopitaux de Paris, Hopital Bichat, INSERM U738, Universite Paris 7 Denis Diderot, Paris, France
    Arthritis Rheum 55:526-30. 2006
    ....
  21. ncbi request reprint Violation of the intent-to-treat principle and rate of missing data in superiority trials assessing structural outcomes in rheumatic diseases
    Gabriel Baron
    INSERM U 738, Groupe Hospitalier Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, Paris, France
    Arthritis Rheum 52:1858-65. 2005
    ..To evaluate the methodologic quality of and identify methodologic issues in superiority trials assessing structural outcomes in rheumatic diseases...
  22. doi request reprint EULAR Sjogren's Syndrome Patient Reported Index (ESSPRI): development of a consensus patient index for primary Sjogren's syndrome
    Raphaele Seror
    Center of Clinical Epidemiology, Paris, France
    Ann Rheum Dis 70:968-72. 2011
    ..To develop a score for assessment of patients' symptoms in primary Sjögren's syndrome (SS): the EULAR SS Patient Reported Index (ESSPRI)...
  23. pmc Underrepresentation of elderly people in randomised controlled trials. The example of trials of 4 widely prescribed drugs
    Cécile Konrat
    INSERM U738, Paris, France
    PLoS ONE 7:e33559. 2012
    ..We focused on trials of 4 medications--pioglitazone, rosuvastatin, risedronate, and valsartan-frequently used by elderly patients with chronic medical conditions...
  24. pmc Respective contribution of chronic conditions to disability in France: results from the national Disability-Health Survey
    Clémence Palazzo
    U738, INSERM, Paris, France
    PLoS ONE 7:e44994. 2012
    ..We assessed the respective contribution of chronic health conditions to disability for three age groups (18-40, 40-65, and >65 years old) using data from the 2008-2009 Disability-Health Survey in France...
  25. pmc Development and validation of a questionnaire assessing fears and beliefs of patients with knee osteoarthritis: the Knee Osteoarthritis Fears and Beliefs Questionnaire (KOFBeQ)
    Mathilde Benhamou
    service de rééducation et réadaptation de l appareil locomoteur et des pathologies du rachis, Assistance Publique Hôpitaux de Paris Université Paris Descartes INSERM IFR 25 Handicap, Paris, France
    PLoS ONE 8:e53886. 2013
    ..We aimed to develop a questionnaire assessing fears and beliefs of patients with knee OA...
  26. ncbi request reprint A checklist to evaluate a report of a nonpharmacological trial (CLEAR NPT) was developed using consensus
    Isabelle Boutron
    INSERM U738, Paris, France
    J Clin Epidemiol 58:1233-40. 2005
    ..To develop a checklist of items measuring the quality of reports of randomized clinical trials (RCTs) assessing nonpharmacological treatments (NPTs)...
  27. pmc Minimal clinically important improvement and patient acceptable symptom state for subjective outcome measures in rheumatic disorders
    Florence Tubach
    Département d Epidémiologie, Biostatistique et Recherche Clinique, Hopital Bichat, Paris, France
    J Rheumatol 34:1188-93. 2007
    ..The purpose of this SIG at OMERACT 8 was to inform participants of the MCII and PASS concepts and to agree on MCII and PASS values for pain, patient global assessment, and functional impairment...
  28. doi request reprint Comparison of registered and published primary outcomes in randomized controlled trials
    Sylvain Mathieu
    INSERM, U738, Assistance Publique des Hopitaux de Paris, Hopital Bichat Claude Bernard, Département d Epidémiologie Biostatistique et Recherche Clinique, Paris, France
    JAMA 302:977-84. 2009
    ..As of 2005, the International Committee of Medical Journal Editors required investigators to register their trials prior to participant enrollment as a precondition for publishing the trial's findings in member journals...
  29. pmc Comparison of treatment effect estimates for pharmacological randomized controlled trials enrolling older adults only and those including adults: a meta-epidemiological study
    Valerie Seegers
    Assistance Publique Hopitaux de Paris, Hopital Hotel Dieu, Paris, France
    PLoS ONE 8:e63677. 2013
    ..Older adults are underrepresented in clinical research. To assess therapeutic efficacy in older patients, some randomized controlled trials (RCTs) include older adults only...
  30. pmc Inadequate description of educational interventions in ongoing randomized controlled trials
    Cécile Pino
    INSERM, U738, Paris, France
    Trials 13:63. 2012
    ..We aimed to evaluate the quality of registry descriptions of non-pharmacologic interventions assessed in ongoing randomized controlled trials (RCTs) of patient education...
  31. pmc Adjustment for reporting bias in network meta-analysis of antidepressant trials
    Ludovic Trinquart
    Centre Cochrane Français, Paris, France
    BMC Med Res Methodol 12:150. 2012
    ..Reporting bias is a major threat to the validity of MA and NMA. Numerous methods are available to assess the robustness of MA results to reporting bias. We aimed to extend such methods to NMA...
  32. pmc Case-only designs in pharmacoepidemiology: a systematic review
    Sandra Nordmann
    Univ Paris Diderot, Sorbonne Paris Cité, UMR S 738 INSERM, UMR S 738, Paris, France
    PLoS ONE 7:e49444. 2012
    ....
  33. doi request reprint Misleading abstract conclusions in randomized controlled trials in rheumatology: comparison of the abstract conclusions and the results section
    Sylvain Mathieu
    INSERM U738, Paris, France
    Joint Bone Spine 79:262-7. 2012
    ..Readers of scientific articles often read only the abstract and its conclusions because of lack of time or of access to the full-length articles...
  34. doi request reprint Influence of vertebral fracture assessment by dual-energy X-ray absorptiometry on decision-making in osteoporosis: a structured vignette survey
    Christian Roux
    Rheumatology Department, Paris Descartes University, Paris, France
    Rheumatology (Oxford) 50:2264-9. 2011
    ..This study was designed to assess the impact of VFA results on decision-marking in osteoporosis, using a clinical vignette-based approach...
  35. pmc Reporting of sample size calculation in randomised controlled trials: review
    Pierre Charles
    INSERM, U738, Paris, France
    BMJ 338:b1732. 2009
    ..To assess quality of reporting of sample size calculation, ascertain accuracy of calculations, and determine the relevance of assumptions made when calculating sample size in randomised controlled trials...
  36. doi request reprint Effect of hyaluronic acid in symptomatic hip osteoarthritis: a multicenter, randomized, placebo-controlled trial
    Pascal Richette
    Hopital Lariboisiere, Assistance Publique Hopitaux de Paris, Paris, France
    Arthritis Rheum 60:824-30. 2009
    ..To evaluate the efficacy and tolerability of a single intraarticular (IA) injection of hyaluronic acid (HA) for the treatment of hip osteoarthritis (OA)...
  37. ncbi request reprint Methods and processes of the CONSORT Group: example of an extension for trials assessing nonpharmacologic treatments
    Isabelle Boutron
    INSERM U738, AP HP, Hopital Bichat Claude Bernard, and Université Paris 7 Denis Diderot, Paris, France
    Ann Intern Med 148:W60-6. 2008
    ..The conduct of randomized, controlled trials of nonpharmacologic treatments presents specific challenges that are not adequately addressed in trial reports...
  38. ncbi request reprint Reporting of adherence to medication in recent randomized controlled trials of 6 chronic diseases: a systematic literature review
    Laure Gossec
    AP HP, Rheumatology B Department, Cochin Hospital, 27 rue du Faubourg St Jacques, Paris 5 University, Paris, France
    Am J Med Sci 334:248-54. 2007
    ....
  39. pmc The gap between practice and guidelines in the choice of first-line disease modifying antirheumatic drug in early rheumatoid arthritis: results from the ESPOIR cohort
    Mathilde Benhamou
    Department of Rheumatology, University of Paris VI, Pitie Salpetriere Hospital, Paris, France
    J Rheumatol 36:934-42. 2009
    ....
  40. doi request reprint Single-center trials show larger treatment effects than multicenter trials: evidence from a meta-epidemiologic study
    Agnes Dechartres
    U738 INSERM, Paris, France
    Ann Intern Med 155:39-51. 2011
    ..A recent study suggested that results of single-center trials are frequently contradicted when similar trials are performed in multicenter settings...
  41. pmc Neglected external validity in reports of randomized trials: the example of hip and knee osteoarthritis
    Nizar Ahmad
    INSERM U738, Assistance Publique Hopitaux de Paris, Hopital Bichat Claude Bernard, Universite Paris 7, Paris, France
    Arthritis Rheum 61:361-9. 2009
    ..To evaluate data reporting related to external validity from randomized controlled trials (RCTs) assessing pharmacologic and nonpharmacologic treatment for hip and knee osteoarthritis (OA)...
  42. ncbi request reprint The methods for handling missing data in clinical trials influence sample size requirements
    Guy Robert Auleley
    université Paris V René Descartes, Faculté de Médecine Cochin Port Royal and Clinique de Rhumatologie, Hopital Cochin, AP HP, Paris, France
    J Clin Epidemiol 57:447-53. 2004
    ..Results of studies estimating osteoarthritis progression may be affected by missing values. In clinical trials assessing disease-modifying osteoarthritis drugs, sample sizes should be calculated using close estimates of outcome variables...
  43. ncbi request reprint Minimal clinically important difference, low disease activity state, and patient acceptable symptom state: methodological issues
    Florence Tubach
    Département d Epidémiologie, Biostatistique et Recherche Clinique, Groupe Hospitalier Bichat Claude Bernard AP HP, INSERM U738, Faculté Xavier Bichat Université Paris 7, Paris, France
    J Rheumatol 32:2025-9. 2005
    ..Threshold values for the MCID and LDAS should be determined according to data-driven and experts' opinions and approaches...
  44. pmc Methods of blinding in reports of randomized controlled trials assessing pharmacologic treatments: a systematic review
    Isabelle Boutron
    INSERM U738, Paris, France
    PLoS Med 3:e425. 2006
    ....
  45. ncbi request reprint Effect of a collective educational program for patients with rheumatoid arthritis: a prospective 12-month randomized controlled trial
    Janine Sophie Giraudet-Le Quintrec
    AP HP, Hopital Cochin, Universite Rene Descartes, Faculte de Medecine, Paris, France
    J Rheumatol 34:1684-91. 2007
    ..To evaluate the effect on health and functional status of an 8-week group-education program for rheumatoid arthritis (RA) in addition to usual medical care...
  46. pmc ASSIST applicability scoring of surgical trials. an investigator-reported assessment tool
    Idriss Tourabaly
    INSERM, U738, Paris, France
    PLoS ONE 7:e42258. 2012
    ..We aimed to develop a new tool for assessing and depicting the applicability of the results of surgical randomized controlled trials (RCTs) from the trial investigators' perspective...
  47. pmc Influence of trial sample size on treatment effect estimates: meta-epidemiological study
    Agnes Dechartres
    INSERM, U738, Paris, France
    BMJ 346:f2304. 2013
    ..To assess the influence of trial sample size on treatment effect estimates within meta-analyses...
  48. pmc Impact of evergreening on patients and health insurance: a meta analysis and reimbursement cost analysis of citalopram/escitalopram antidepressants
    Ali A Alkhafaji
    Centre d Epidemiologie Clinique, Hopital Hotel Dieu, Assistance Publique Hopitaux de Paris, 1 Place du Parvis Notre Dame, Paris, 75004, France
    BMC Med 10:142. 2012
    ....
  49. ncbi request reprint Quality of reporting of noninferiority and equivalence randomized trials
    Anne Le Henanff
    Institut National de la Santé et de la Recherche Médicale INSERM U738, Paris, France
    JAMA 295:1147-51. 2006
    ..These study objectives imply particular planning and analysis...
  50. doi request reprint Reporting of safety results in published reports of randomized controlled trials
    Isabelle Pitrou
    Département d Epidémiologie, Biostatistique, et Recherche Clinique, Groupe Hospitalier Bichat Claude Bernard AP HP, Universite Denis Diderot, INSERM U738, Paris, France
    Arch Intern Med 169:1756-61. 2009
    ..Poor safety reporting can lead to misinterpretation and inadequate conclusions about the interventions assessed. Our aim was to describe the reporting of harm-related results from randomized controlled trials (RCTs)...
  51. doi request reprint Inadequate planning and reporting of adjudication committees in clinical trials: recommendation proposal
    Agnes Dechartres
    INSERM U738, Paris, France
    J Clin Epidemiol 62:695-702. 2009
    ..We aimed to assess the reporting and functioning of ACs (synonyms: clinical event committees, endpoint committees) in clinical trials...
  52. pmc Delphi-consensus weights for ischemic and bleeding events to be included in a composite outcome for RCTs in thrombosis prevention
    Agnes Dechartres
    UMR S 738, INSERM, Paris, France
    PLoS ONE 6:e18461. 2011
    ..To weight ischemic and bleeding events according to their severity to be used in a composite outcome in RCTs in the field of thrombosis prevention...
  53. ncbi request reprint Data capture by digital pen in clinical trials: a qualitative and quantitative study
    Candice Estellat
    INSERM U738, Paris, France
    Contemp Clin Trials 29:314-23. 2008
    ..To investigate the use of the digital pen (DP) system to collect data in a clinical trial. To assess the accuracy of the system in this setting...
  54. pmc A priori postulated and real power in cluster randomized trials: mind the gap
    Lydia Guittet
    Département d Epidémiologie, Biostatistique et Recherche Clinique, Groupe Hospitalier Bichat Claude Bernard AP HP Université Paris 7, Paris, France
    BMC Med Res Methodol 5:25. 2005
    ..The intraclass correlation coefficient (ICC) defines the clustering effect and be specified during planning. The aim of this work is to study the influence of the ICC on power in cluster randomized trials...
  55. pmc Living with HIV, antiretroviral treatment experience and tobacco smoking: results from a multisite cross-sectional study
    Xavier Duval
    INSERM, Clinical Investigation Center 007, Inserm 738, Bichat, Paris, France
    Antivir Ther 13:389-97. 2008
    ..To assess the prevalence of and factors associated with tobacco smoking and dependence in HIV patients...
  56. doi request reprint Determinants of the survival benefit of lung transplantation in patients with chronic obstructive pulmonary disease
    Gabriel Thabut
    Service de Pneumologie B et Transplantation Pulmonaire, Hopital Bichat, 46 rue Henri Huchard, 75018 Paris, France
    Am J Respir Crit Care Med 177:1156-63. 2008
    ..Although chronic obstructive pulmonary disease is the first indication for lung transplantation, the benefit of the procedure in terms of survival remains debated...
  57. pmc Applicability and generalisability of the results of systematic reviews to public health practice and policy: a systematic review
    Nizar Ahmad
    Centre d Epidemiologie Clinique, Hopital Hotel Dieu, AP HP Assistance Publique des Hôpitaux de Paris, 1 Place du Parvis Notre Dame, Paris 75181, France
    Trials 11:20. 2010
    ..e., whether the results of a trial can be reasonably applied or generalized to a definable group of patients in a particular setting in routine practice, also called external validity or generalisability)...
  58. ncbi request reprint Impact of HAART advent on admission patterns and survival in HIV-infected patients admitted to an intensive care unit
    Enrique Casalino
    Infectious Diseases Intensive Care Unit and the Epidemiology and Biostatistics Department, Bichat Claude Bernard University Hospital, Paris, France
    AIDS 18:1429-33. 2004
    ..Several studies found increased survival times and decreased hospitalization rates since the introduction of highly active antiretroviral therapy (HAART)...
  59. doi request reprint Reporting and interpretation of randomized controlled trials with statistically nonsignificant results for primary outcomes
    Isabelle Boutron
    Centre for Statistics in Medicine, University of Oxford, Oxford, United Kingdom
    JAMA 303:2058-64. 2010
    ..Previous studies indicate that the interpretation of trial results can be distorted by authors of published reports...
  60. doi request reprint Heterogeneity of tumor prognostic markers: a reproducibility study applied to liver metastases of pancreatic endocrine tumors
    Anne Couvelard
    Department of Pathology, University of Paris 7, Assistance Publique Hopitaux de Paris, Beaujon Hospital, Clichy, France
    Mod Pathol 22:273-81. 2009
    ..Sampling variability should be taken into consideration as a potential limitation to the assessment of prognostic and therapeutic markers in biopsy samples from metastatic pancreatic endocrine tumors...
  61. pmc Risk score to predict serious bleeding in stable outpatients with or at risk of atherothrombosis
    Gregory Ducrocq
    INSERM U 698 Recherche Clinique en Athérothrombose, Department of Cardiology, Centre Hospitalier Universitaire Bichat Claude Bernard, 46 rue Henri Huchard, Paris Cedex, France
    Eur Heart J 31:1257-65. 2010
    ..To develop a risk score to quantify bleeding risk in outpatients with or at risk of atherothrombosis...
  62. ncbi request reprint Anal squamous intraepithelial lesions and condyloma in HIV-infected heterosexual men, homosexual men and women: prevalence and associated factors
    Laurent Abramowitz
    Department of Gastroenterology and Proctology, Bichat Hospital, Paris, France
    AIDS 21:1457-65. 2007
    ..To assess the prevalence of and factors associated with squamous intraepithelial lesions and condyloma [human papillomavirus (HPV)-related lesions) in HIV-infected patients...
  63. pmc Reporting of radiographic methods in randomised controlled trials assessing structural outcomes in rheumatoid arthritis
    Gabriel Baron
    Département d Epidémiologie Biostatistique et Recherche Clinique, INSERM, U738, Groupe Hospitalier Bichat Claude Bernard, 46 rue Henri Huchard, 75018 Paris, France
    Ann Rheum Dis 66:651-7. 2007
    ....
  64. ncbi request reprint Recommendations of the French Society for Rheumatology. TNFalpha antagonist therapy in rheumatoid arthritis
    Bruno Fautrel
    Service de Rhumatologie, Groupe Hospitalier Pitie Salpetriere, UFR de Medecine, Universite Pierre et Marie Curie Paris VI, 83, Boulevard de l Hopital, 75651 Paris Cedex 13, France
    Joint Bone Spine 73:433-41. 2006
    ..To develop recommendations for TNFalpha-antagonist therapy in patients with rheumatoid arthritis (RA) seen in everyday practice, under the aegis of the French Society for Rheumatology...
  65. ncbi request reprint Recommendations of the French Society for Rheumatology regarding TNFalpha antagonist therapy in patients with rheumatoid arthritis
    Bruno Fautrel
    Pierre and Marie Curie University Paris VI, UFR de Medecine, France
    Joint Bone Spine 74:627-37. 2007
    ..To update French Society for Rheumatology guidelines regarding the use of TNFalpha antagonists for treating patients with rheumatoid arthritis (RA)...
  66. doi request reprint Plasma proteome to look for diagnostic biomarkers of early bacterial sepsis after liver transplantation: a preliminary study
    Catherine Paugam-Burtz
    Department of Anesthesiology and Critical Care, University Hospital, Assistance Publique Hopitaux de Paris, Hopital Beaujon, Bd du Général Leclerc, Clichy, France
    Anesthesiology 112:926-35. 2010
    ..This study used plasma profiling coupling Proteinchip array with surface-enhanced laser desorption ionization time-of-fly mass spectrometry to search for biomarkers of postoperative sepsis in patients who underwent liver transplantation...
  67. ncbi request reprint Influence of patient education on exercise compliance in rheumatoid arthritis: a prospective 12-month randomized controlled trial
    Anne Mayoux-Benhamou
    Department of Rehabilitation, Cochin Hospital, 27 rue du Faubourg Saint Jacques, 75679 Paris Cedex 14, France
    J Rheumatol 35:216-23. 2008
    ..To determine the effect of education on the exercise habits of patients with rheumatoid arthritis (RA) after 6 and 12 months...
  68. doi request reprint Missing data in randomized controlled trials of rheumatoid arthritis with radiographic outcomes: a simulation study
    Gabriel Baron
    AP HP, Hopital Bichat, Biostatistique et Recherche Clinique, INSERM, U738, and Université Paris, France
    Arthritis Rheum 59:25-31. 2008
    ..To assess the impact, in terms of statistical power and bias of treatment effect, of approaches to dealing with missing data in randomized controlled trials of rheumatoid arthritis with radiographic outcomes...
  69. doi request reprint Maintenance of infliximab treatment in ankylosing spondylitis: results of a one-year randomized controlled trial comparing systematic versus on-demand treatment
    Maxime Breban
    Hopital Ambroise Pare, Assistance Publique Hopitaux de Paris, Boulogne Billancourt, France
    Arthritis Rheum 58:88-97. 2008
    ..This study was undertaken to compare the efficacy of continuous treatment with infliximab with that of a treatment regimen adapted to symptom recurrence. Methotrexate (MTX) in combination with infliximab was also tested...
  70. doi request reprint Drug-specific risk of non-tuberculosis opportunistic infections in patients receiving anti-TNF therapy reported to the 3-year prospective French RATIO registry
    D Salmon-Ceron
    Service de Rhumatologie, Hopital Bicetre, 78 rue du General Leclerc, 94275 Le Kremlin Bicetre
    Ann Rheum Dis 70:616-23. 2011
    ..Anti-tumour necrosis factor (TNF) therapy may be associated with opportunistic infections (OIs)...
  71. pmc Participant informed consent in cluster randomized trials: review
    Bruno Giraudeau
    INSERM, U738, Paris, France
    PLoS ONE 7:e40436. 2012
    ..We assessed whether participant informed consent was required in such trials, which type of consent was required, and whether the trial was at risk of selection bias because of the very nature of participant information...
  72. pmc Development and description of measurement properties of an instrument to assess treatment burden among patients with multiple chronic conditions
    Viet Thi Tran
    Universite Paris Descartes, Faculte de Medecine, Paris, France
    BMC Med 10:68. 2012
    ..This treatment burden could affect treatment adherence, quality of life and outcomes. We aimed to develop and validate an instrument for measuring treatment burden for patients with multiple chronic conditions...
  73. pmc Agreement among health care professionals in diagnosing case Vignette-based surgical site infections
    Didier Lepelletier
    Infection Control Unit, Bichat Claude Bernard Hospital, Assistance Publique Hopitaux de Paris, Paris, France
    PLoS ONE 7:e35131. 2012
    ..To assess agreement in diagnosing surgical site infection (SSI) among healthcare professionals involved in SSI surveillance...
  74. pmc Impact of single centre status on estimates of intervention effects in trials with continuous outcomes: meta-epidemiological study
    Aïda Bafeta
    INSERM U738, Paris, France
    BMJ 344:e813. 2012
    ..To compare estimates of intervention effects between single centre and multicentre randomised controlled trials with continuous outcomes...
  75. doi request reprint Metformin use and mortality among patients with diabetes and atherothrombosis
    Ronan Roussel
    INSERM, Department of Diabetology, Bichat Hospital, Paris, France
    Arch Intern Med 170:1892-9. 2010
    ..However, metformin is often not considered in patients with cardiovascular conditions because of concerns about its safety...
  76. doi request reprint Systematic review reveals heterogeneity in definition of a clinically relevant difference in pain
    Adeline Ruyssen-Witrand
    Paris 7 Denis Diderot University, Medecine Faculty, Paris, France
    J Clin Epidemiol 64:463-70. 2011
    ..To describe the pain decrease considered as clinically relevant when designing a trial and reporting its results...
  77. doi request reprint Accurate detection of changes in disease activity in primary Sjögren's syndrome by the European League Against Rheumatism Sjögren's Syndrome Disease Activity Index
    Raphaele Seror
    Department of Epidemiology, Biostatistics, and Clinical Research, Hopital Bichat, INSERM U738, 46 rue Henri Huchard, Paris, France
    Arthritis Care Res (Hoboken) 62:551-8. 2010
    ..To assess and compare the sensitivity to change of the European League Against Rheumatism Sjögren's Syndrome Disease Activity Index (ESSDAI) with that of other primary Sjögren's syndrome (SS) disease activity indexes...
  78. ncbi request reprint Noninvitation of eligible individuals to participate in pediatric studies: a qualitative study
    Philippe Amiel
    Institut Gustave Roussy, Villejuif, Unité de Recherche en Sciences Humaines et Sociales, Assistance Publique Hopitaux de Paris, Hopital Robert Debre, Paris, France
    Arch Pediatr Adolesc Med 161:446-50. 2007
    ..To identify subjective factors that lead investigators not to invite eligible individuals to participate in pediatric studies...
  79. doi request reprint Comparison of clinical presentations and outcomes between patients with TGFBR2 and FBN1 mutations in Marfan syndrome and related disorders
    David Attias
    Centre de référence pour le syndrome de Marfan et apparentés, Hopital Bichat, Paris, France
    Circulation 120:2541-9. 2009
    ..TGFBR2 mutations were recognized recently among patients with a Marfan-like phenotype. The associated clinical and prognostic spectra remain unclear...
  80. pmc Applicability and generalisability of published results of randomised controlled trials and non-randomised studies evaluating four orthopaedic procedures: methodological systematic review
    Leslie Pibouleau
    INSERM U738, Paris, France
    BMJ 339:b4538. 2009
    ..To compare the reporting of essential applicability data from randomised controlled trials and non-randomised studies evaluating four new orthopaedic surgical procedures...
  81. ncbi request reprint A review of blinding in randomized controlled trials found results inconsistent and questionable
    Isabelle Boutron
    INSERM, U738, Paris, France
    J Clin Epidemiol 58:1220-6. 2005
    ..To determine methods to assess the success of blinding in randomized controlled trials (RCTs)...
  82. pmc The reporting of randomized clinical trials using a surgical intervention is in need of immediate improvement: a systematic review
    Isabelle Jacquier
    INSERM U738, Paris France corrected Assistance Publique Hôpitaux de Paris APHP, Groupe Hospitalier Bichat Claude Bernard, Département d Epidémiologie Biostatistique et Recherche Clinique, Paris, France
    Ann Surg 244:677-83. 2006
    ..To assess the reporting of surgical interventions, care providers, and number of centers in randomized clinical trials...
  83. doi request reprint How to perform a critical analysis of a randomised controlled trial
    Candice Estellat
    INSERM U738, Department d Epidémiologie, de Biostatistique et de Recherche Clinique, Groupe Hospitalier Bichat Claude Bernard, Paris, France
    Best Pract Res Clin Rheumatol 23:291-303. 2009
    ..Finally, we raise the issue of external validity and of reporting adverse effects to determine which patients may best benefit from the new intervention...
  84. doi request reprint Reporting of corticosteroid use in systemic disease trials: evidence from a systematic review of the potential impact on treatment effect
    Christian Pagnoux
    INSERM U738, Universite Paris Diderot, Hopital Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, Universite Paris Descartes, Paris, France
    Arthritis Care Res (Hoboken) 62:1002-8. 2010
    ..To study how corticosteroid therapy is planned and described in reports of systemic disease trials and estimate the impact of the between-arm difference in corticosteroid dose on treatment effect...
  85. ncbi request reprint Long-term impact of a restrictive laboratory test ordering form on tumor marker prescriptions
    Pierre Durieux
    Department of Public Health and Medical Informatics, Faculté de Médecine Broussais Hôtel Dieu, Paris, France
    Int J Technol Assess Health Care 19:106-13. 2003
    ..To evaluate the long-term impact of an intervention designed to reduce the ordering of three tumor markers frequently prescribed for gastroenterologic diseases (carcinoembryonic antigen, alpha-fetoprotein, carbohydrate antigen 19-9)...
  86. ncbi request reprint Amyloid arthropathy in the course of multiple myeloma
    Bruno Fautrel
    Rheumatology Institute, Hĵpital Cochin, Paris, France
    J Rheumatol 29:1473-81. 2002
    ..Primary amyloidosis is classical in the course of multiple myeloma (MM), but peripheral amyloid arthropathy is unusual. We evaluated the frequency and effect of amyloid arthropathy in a single center series of patients with MM...
  87. pmc A home-visiting intervention targeting determinants of infant mental health: the study protocol for the CAPEDP randomized controlled trial in France
    Florence Tubach
    AP HP, Hopital Bichat, Département d Epidémiologie et Recherche Clinique, 46 rue Henri Huchard, secteur Claude Bernard, 75877 Paris Cedex 18, Paris, France
    BMC Public Health 12:648. 2012
    ..Several studies suggest that the number of risk factors rather than their nature is key to mental health disorders in childhood...
  88. pmc Quality of reporting of bioequivalence trials comparing generic to brand name drugs: a methodological systematic review
    Amélie van der Meersch
    INSERM, U738, Paris, France
    PLoS ONE 6:e23611. 2011
    ..Generic drugs are used by millions of patients for economic reasons, so their evaluation must be highly transparent...
  89. ncbi request reprint Impact of ultrasound imaging on local corticosteroid injections of symptomatic ankle, hind-, and mid-foot in chronic inflammatory diseases
    Maria Antonietta d'Agostino
    Cochin Hospital, and Université René Descartes, Paris, France
    Arthritis Rheum 53:284-92. 2005
    ..To assess the impact of ultrasonography (US) on local corticosteroid (CS) injections of painful ankle, hindfoot, and midfoot in chronic inflammatory diseases...
  90. doi request reprint Survival after bilateral versus single lung transplantation for patients with chronic obstructive pulmonary disease: a retrospective analysis of registry data
    Gabriel Thabut
    Service de Pneumologie B et Transplantation Pulmonaire, Hopital Bichat, APHP et Université Paris Diderot, Paris 7, Paris, France
    Lancet 371:744-51. 2008
    ..We aimed to compare survival after each procedure by analysing data from the registry of the International Society for Heart and Lung Transplantation...
  91. doi request reprint Lack of head-to-head trials and fair control arms: randomized controlled trials of biologic treatment for rheumatoid arthritis
    Candice Estellat
    Département d Epidémiologie et Recherche Clinique, Hopital Bichat, Paris, France
    Arch Intern Med 172:237-44. 2012
    ..We herein describe the control arms and the treatment received by patients in recently conducted or ongoing randomized controlled trials of biologic disease-modifying antirheumatic drugs (DMARDs) for rheumatoid arthritis...
  92. pmc Quality of reporting internal and external validity data from randomized controlled trials evaluating stents for percutaneous coronary intervention
    Morgane Ethgen
    Institut National de la Santé et la Recherche Médiale, INSERM U738, Paris, France
    BMC Med Res Methodol 9:24. 2009
    ..The objective of our study was to evaluate the quality of reporting internal and external validity data in published reports of RCTs assessing the stents for percutaneous coronary interventions...
  93. ncbi request reprint Social and personal consequences of disability in adults with hip and knee arthroplasty. A French national community based survey
    Isabelle Boutron
    National Institute of Statistics and Economic Studies INSEE, Paris, France
    J Rheumatol 31:759-66. 2004
    ..To describe and compare participation restrictions and environmental factors of persons with and without hip or knee arthroplasty in a national community based survey: the Handicap, Disability, Dependence Survey...
  94. pmc Outcome and serum ion determination up to 11 years after implantation of a cemented metal-on-metal hip prosthesis
    Jean Yves Lazennec
    Department of Orthopaedic Surgery, Pitie Salpetriere Hospital, Paris, France
    Acta Orthop 80:168-73. 2009
    ..Little is known about the long-term outcome of cemented metal-on-metal hip arthroplasties. We evaluated a consecutive series of metal-on-metal polyethylene-backed cemented hip arthroplasties implanted in patients under 60 years of age...
  95. ncbi request reprint The RATIO observatory: French registry of opportunistic infections, severe bacterial infections, and lymphomas complicating anti-TnFalpha therapy
    Florence Tubach
    INSERM U738, Bichat Teaching Hospital, Xavier Bichat School of Medicine, Paris 7 University, Paris, France
    Joint Bone Spine 72:456-60. 2005
    ....
  96. ncbi request reprint Methodological differences in clinical trials evaluating nonpharmacological and pharmacological treatments of hip and knee osteoarthritis
    Isabelle Boutron
    Département d Epidémiologie, Biostatistique et Recherche Clinique, Groupe Hospitalier Bichat Claude Bernard, Assistance Publique des Hopitaux de Paris, Faculte Xavier Bichat, Universite Paris VII, Paris, France
    JAMA 290:1062-70. 2003
    ....
  97. doi request reprint Antibiotic use: knowledge and perceptions in two university hospitals
    Jean Christophe Lucet
    Infection Control Unit, Bichat Claude Bernard Hospital, Assistance Publique Hopitaux de Paris, and Denis Diderot University, Paris, France
    J Antimicrob Chemother 66:936-40. 2011
    ..To investigate knowledge and perceptions about antibiotic prescription in two university hospitals...
  98. ncbi request reprint Decision-making in elderly patients with severe aortic stenosis: why are so many denied surgery?
    Bernard Iung
    Cardiology Department, Bichat Hospital, AP HP, Paris, France
    Eur Heart J 26:2714-20. 2005
    ..To analyse decision-making in elderly patients with severe, symptomatic aortic stenosis (AS)...
  99. ncbi request reprint A prospective survey of patients with valvular heart disease in Europe: The Euro Heart Survey on Valvular Heart Disease
    Bernard Iung
    Cardiology Department, Bichat Hospital, AP HP, Paris, France
    Eur Heart J 24:1231-43. 2003
    ..To identify the characteristics, treatment, and outcomes of contemporary patients with valvular heart disease (VHD) in Europe, and to examine adherence to guidelines...
  100. ncbi request reprint High-dose therapy and autologous blood stem-cell transplantation compared with conventional treatment in myeloma patients aged 55 to 65 years: long-term results of a randomized control trial from the Group Myelome-Autogreffe
    Jean Paul Fermand
    Immuno Hematology Unit and Department of Biostatistics, Hopital Saint Louis, Paris, France
    J Clin Oncol 23:9227-33. 2005
    ..To study the impact of high-dose therapy (HDT) with autologous stem-cell support in patients with symptomatic multiple myeloma (MM) between the ages of 55 and 65 years...
  101. ncbi request reprint Predischarge C-reactive protein and 1-year outcome after acute coronary syndromes
    Philippe Gabriel Steg
    Department of Cardiology, Hopital Bichat, Paris, France
    Am J Med 119:684-92. 2006
    ..To investigate the relationship between high-sensitivity C-reactive protein and cardiovascular events following acute coronary syndrome...