Minoo Rassoulzadegan

Summary

Country: France

Publications

  1. ncbi request reprint Inheritance of an epigenetic change in the mouse: a new role for RNA
    M Rassoulzadegan
    Inserm U636, Ligue Nationale Contre le Cancer, F 06108 Nice, France
    Biochem Soc Trans 35:623-5. 2007
  2. pmc The making of an organ: RNA mediated developmental controls in mice
    Minoo Rassoulzadegan
    Inserm U636, F 06108, Nice, France
    Organogenesis 6:33-6. 2010
  3. pmc APLP2, a member of the Alzheimer precursor protein family, is required for correct genomic segregation in dividing mouse cells
    M Rassoulzadegan
    Unité 470 de l Institut National de la Santé et de la Recherche Médicale, Universite de Nice, 06108 Nice, France
    EMBO J 17:4647-56. 1998
  4. ncbi request reprint Sperm RNA, an "epigenetic rheostat" of gene expression?
    Minoo Rassoulzadegan
    INSERM, U636, F 06108, Nice, France
    Arch Androl 53:235-8. 2007
  5. ncbi request reprint RNA-mediated non-mendelian inheritance of an epigenetic change in the mouse
    Minoo Rassoulzadegan
    INSERM, U636, F 06108 Nice, France
    Nature 441:469-74. 2006
  6. ncbi request reprint A novel germ line-specific gene of the phosducin-like protein (PhLP) family. A meiotic function conserved from yeast to mice
    Pascal Lopez
    University of Nice, INSERM U470, 06108 Nice, France
    J Biol Chem 278:1751-7. 2003
  7. pmc RNA-mediated epigenetic heredity requires the cytosine methyltransferase Dnmt2
    Jafar Kiani
    University of Nice Sophia Antipolis, UFR Sciences, Nice, France
    PLoS Genet 9:e1003498. 2013
  8. doi request reprint RNA induction and inheritance of epigenetic cardiac hypertrophy in the mouse
    Kay D Wagner
    Inserm U636, F 06108 Nice, France
    Dev Cell 14:962-9. 2008
  9. pmc Inheritance of an epigenetic mark: the CpG DNA methyltransferase 1 is required for de novo establishment of a complex pattern of non-CpG methylation
    Valerie Grandjean
    INSERM, U636, Nice, France
    PLoS ONE 2:e1136. 2007
  10. doi request reprint The miR-124-Sox9 paramutation: RNA-mediated epigenetic control of embryonic and adult growth
    Valerie Grandjean
    Inserm U636, F 06108 Nice, France
    Development 136:3647-55. 2009

Collaborators

  • Yanmin Yang
  • François Cuzin
  • Nicole Wagner
  • Philippe Kastner
  • V Grandjean
  • DEBRA WOLGEMUTH
  • Jafar Kiani
  • Pascal Lopez
  • Hossein Ghanbarian
  • Serge Luquet
  • Frédérique Vidal
  • Kay D Wagner
  • Virginie Olive
  • Pierre Gounon
  • Helene Gilgenkrantz
  • Ahmadreza Niavarani
  • Isabelle Gillot
  • Sanny S W Chung
  • Luis A Lopez-Fernandez
  • Galicia Giuili
  • Reinhard Liebers
  • Francesca Tuorto
  • Frank Lyko
  • Christine Vannetti
  • Susan Chan
  • Somaye Dehghanizadeh
  • Sirous Zeinali
  • Paul Grimaldi
  • Marc Magliano
  • Mohsen Karimi
  • Chantal Jehl-Pietri
  • Dorte Holst
  • Joaquin Lopez-Soriano
  • Judith Melki
  • Daniel Puel
  • Philippe Clertant
  • Paul A Grimaldi
  • Ruken Yaman
  • Alexandre Fredenrich
  • Jean François Rual
  • Barry S Rosen
  • Luc Martin
  • Nathalie Labrecque
  • Andrea Tomljenovic
  • Mustapha Oulad-Abdelghani

Detail Information

Publications24

  1. ncbi request reprint Inheritance of an epigenetic change in the mouse: a new role for RNA
    M Rassoulzadegan
    Inserm U636, Ligue Nationale Contre le Cancer, F 06108 Nice, France
    Biochem Soc Trans 35:623-5. 2007
    ..Paramutation may be considered to be one possibility of epigenetic modification in the case of familial disease predispositions that are not fully accounted for by Mendelian analysis...
  2. pmc The making of an organ: RNA mediated developmental controls in mice
    Minoo Rassoulzadegan
    Inserm U636, F 06108, Nice, France
    Organogenesis 6:33-6. 2010
    ..In this essay, we will focus on the evidence showing that RNA molecules are present in the gametes and that RNA can modulate the robust genetic program of organ formation in the mouse...
  3. pmc APLP2, a member of the Alzheimer precursor protein family, is required for correct genomic segregation in dividing mouse cells
    M Rassoulzadegan
    Unité 470 de l Institut National de la Santé et de la Recherche Médicale, Universite de Nice, 06108 Nice, France
    EMBO J 17:4647-56. 1998
    ..Daughter cells derived from a GFP-positive cell showed abnormal DNA contents both >4C and <2C, thus indicating a role for the protein in the mitotic segregation of the genome and establishment of the proper nuclear structure...
  4. ncbi request reprint Sperm RNA, an "epigenetic rheostat" of gene expression?
    Minoo Rassoulzadegan
    INSERM, U636, F 06108, Nice, France
    Arch Androl 53:235-8. 2007
  5. ncbi request reprint RNA-mediated non-mendelian inheritance of an epigenetic change in the mouse
    Minoo Rassoulzadegan
    INSERM, U636, F 06108 Nice, France
    Nature 441:469-74. 2006
    ..Our results identify an unexpected mode of epigenetic inheritance associated with the zygotic transfer of RNA molecules...
  6. ncbi request reprint A novel germ line-specific gene of the phosducin-like protein (PhLP) family. A meiotic function conserved from yeast to mice
    Pascal Lopez
    University of Nice, INSERM U470, 06108 Nice, France
    J Biol Chem 278:1751-7. 2003
    ..Expression of the murine protein was found to complement the defect of a yeast plp2 Delta mutant. We propose that MgcPhLP/Plp2 proteins exert a function in germ cell maturation that is conserved from yeast to mammals...
  7. pmc RNA-mediated epigenetic heredity requires the cytosine methyltransferase Dnmt2
    Jafar Kiani
    University of Nice Sophia Antipolis, UFR Sciences, Nice, France
    PLoS Genet 9:e1003498. 2013
    ..Together, these findings uncover a novel function of Dnmt2 in RNA-mediated epigenetic heredity...
  8. doi request reprint RNA induction and inheritance of epigenetic cardiac hypertrophy in the mouse
    Kay D Wagner
    Inserm U636, F 06108 Nice, France
    Dev Cell 14:962-9. 2008
    ..These results highlight the diversity of RNA-mediated epigenetic effects and may provide a paradigm for clinical cases of familial diseases whose inheritance is not fully explained in Mendelian terms...
  9. pmc Inheritance of an epigenetic mark: the CpG DNA methyltransferase 1 is required for de novo establishment of a complex pattern of non-CpG methylation
    Valerie Grandjean
    INSERM, U636, Nice, France
    PLoS ONE 2:e1136. 2007
    ..As predicted, non-CpG DNA methylation profiles were abrogated in a mutant lacking Dnmt1, the enzymes responsible for CpG methylation, but not in mutants defective for either Dnmt3a or Dnmt2...
  10. doi request reprint The miR-124-Sox9 paramutation: RNA-mediated epigenetic control of embryonic and adult growth
    Valerie Grandjean
    Inserm U636, F 06108 Nice, France
    Development 136:3647-55. 2009
    ..While the heritability of body size is not readily accounted for by Mendelian genetics, our results suggest the alternate model of RNA-mediated heritable epigenetic modifications...
  11. pmc Murine spermatogonial stem cells: targeted transgene expression and purification in an active state
    Galicia Giuili
    Unité 470 de l INSERM, Universite de Nice, France
    EMBO Rep 3:753-9. 2002
    ..A 700-fold enrichment in stem cells was determined by the ability of the purified fractions to re-establish spermatogenesis in germ cell-depleted recipient testes...
  12. ncbi request reprint PU.1 (Sfpi1), a pleiotropic regulator expressed from the first embryonic stages with a crucial function in germinal progenitors
    Virginie Olive
    Inserm U636, F 06108, Nice, France
    Development 134:3815-25. 2007
    ..5 in the embryonic ectoderm. PU.1 therefore appears to play a determinant role in at least two distinct lineages and, given its wide range of expression, possibly in other stem cells...
  13. doi request reprint Non-Mendelian epigenetic heredity: gametic RNAs as epigenetic regulators and transgenerational signals
    François Cuzin
    Inserm U636, F 06108 Nice, France
    Essays Biochem 48:101-6. 2010
    ..Extension from mouse models to human heredity, obviously speculative at present, is encouraged by the high load of RNA in human sperm...
  14. pmc Gene control in germinal differentiation: RNF6, a transcription regulatory protein in the mouse sertoli cell
    Pascal Lopez
    Unité 470 de l Institut National de la Santé et de la Recherche Médicale, Universite de Nice, Nice, France
    Mol Cell Biol 22:3488-96. 2002
    ..In a Sertoli tumor cell line in which expression of both Inha and Rnf6 was reduced, reexpression of the latter restored the level of Inha while, concomitantly, the cells reverted to normal growth control in culture...
  15. doi request reprint Inherited variation at the epigenetic level: paramutation from the plant to the mouse
    François Cuzin
    Inserm U636, F 06108 Nice, France
    Curr Opin Genet Dev 18:193-6. 2008
    ....
  16. pmc A load of small RNAs in the sperm - how many bits of hereditary information?
    Jafar Kiani
    INSERM, U1091, Nice, F 06108, France
    Cell Res 23:18-9. 2013
    ..The finding of these short fragments of tRNA in the sperm raises once again the question of the possible function(s) of such a miniaturized form of information carried by the spermatozoon...
  17. pmc Transvection effects involving DNA methylation during meiosis in the mouse
    Minoo Rassoulzadegan
    Unité 470, Institut National de la Sante et de la Recherche Medicale, Universite de Nice Sophia Antipolis, Nice, France
    EMBO J 21:440-50. 2002
    ..Therefore, these processes depend on a physiological mechanism of establishment and extension of an epigenetic state, for which they provide an experimental model...
  18. ncbi request reprint Conquering the male germ line
    Minoo Rassoulzadegan
    Nat Genet 30:133-4. 2002
  19. ncbi request reprint Peroxisome proliferator-activated receptor delta controls muscle development and oxidative capability
    Serge Luquet
    INSERM U470, Centre de Biochimie, Parc Valrose, Universite de Nice Sophia Antipolis, 06108 Nice Cedex 2, France
    FASEB J 17:2299-301. 2003
    ..They strongly support the idea that activation of PPARdelta could be beneficial in prevention of metabolic disorders, such as obesity or type 2 diabetes...
  20. ncbi request reprint [Germ stem cells: from basic knowledge to their use in gene transfer]
    François Cuzin
    Med Sci (Paris) 19:653-6. 2003
  21. ncbi request reprint Development of transgenic mice expressing calcitonin as a beta-lactoglobulin fusion protein in mammary gland
    Ahmadreza Niavarani
    Department of Biotechnology, Pasteur Institute of Iran, Tehran, Iran
    Transgenic Res 14:719-27. 2005
    ..Calcitonin can thus be expressed under the oBLG promoter and regulatory elements in a mammary-gland specific manner...
  22. ncbi request reprint Germ cells and fatty acids induce translocation of CD36 scavenger receptor to the plasma membrane of Sertoli cells
    Isabelle Gillot
    INSERM UMR 636, Universite de Nice Sophia Antipolis, Faculty of Sciences Parc Valrose, 06108 Nice Cedex 2, France
    J Cell Sci 118:3027-35. 2005
    ..In the testis, CD36 plays a key role in both phagocytosis and lipid recycling, for constant production of mature spermatozoa...
  23. pmc Primary spermatocyte-specific Cre recombinase activity in transgenic mice
    Sanny S W Chung
    Department of Genetics and Development, Columbia University Medical Center, 630 W 168th Street, New York, NY 10032, USA
    Transgenic Res 13:289-94. 2004
    ..Robust expression of X-gal was detected in early to mid-late spermatocytes at stages V-VIII. We conclude that this transgenic line is a powerful tool for deleting genes of interest specifically during male meiosis...
  24. ncbi request reprint [Non-mendelian inheritance take over from RNA or revisited gene]
    Helene Gilgenkrantz
    INSERM U567, CNRSUMR 81 04, Institut Cochin, 24, rue du Faubourg Saint Jacques, 75014 Paris, France
    Med Sci (Paris) 22:669. 2006