Didier Raoult

Summary

Country: France

Publications

  1. ncbi request reprint Molecular identification of a collection of spotted Fever group rickettsiae obtained from patients and ticks from Russia
    Stanislav N Shpynov
    Unite des Rickettsies, Faculte de Medecine, Marseille, France
    Am J Trop Med Hyg 74:440-3. 2006
  2. pmc Tropheryma whipplei Twist: a human pathogenic Actinobacteria with a reduced genome
    Didier Raoult
    Unite des Rickettsies, Faculte de Medecine, CNRS UMR6020, Universite de la Mediterranee, 13385 Marseille Cedex 05, France
    Genome Res 13:1800-9. 2003
  3. ncbi request reprint Molecular genetic methods for the diagnosis of fastidious microorganisms
    Florence Fenollar
    Unite des Rickettsies, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    APMIS 112:785-807. 2004
  4. ncbi request reprint rpoB gene sequence-based characterization of emerging non-tuberculous mycobacteria with descriptions of Mycobacterium bolletii sp. nov., Mycobacterium phocaicum sp. nov. and Mycobacterium aubagnense sp. nov
    Toidi Adekambi
    Unite des Rickettsies, CNRS UMR 6020 IFR 48, Faculte de Medecine, 27, Boulevard Jean Moulin, Université de la Méditerranée and Assistance Publique Hôpitaux de Marseille Timone, Fédération de Microbiologie Clinique, Marseille, France
    Int J Syst Evol Microbiol 56:133-43. 2006
  5. ncbi request reprint Rickettsia tamurae sp. nov., isolated from Amblyomma testudinarium ticks
    Pierre Edouard Fournier
    Unite des Rickettsies, IFR 48, CNRS UMR 6020, Faculte de Medecine, Universite de la Mediterranee, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France
    Int J Syst Evol Microbiol 56:1673-5. 2006
  6. pmc Genomic analysis of an emerging multiresistant Staphylococcus aureus strain rapidly spreading in cystic fibrosis patients revealed the presence of an antibiotic inducible bacteriophage
    Jean Marc Rolain
    URMITE CNRS IRD UMR 6236, Faculte de Medecine et de Pharmacie, Universite de la Mediterranee, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France
    Biol Direct 4:1. 2009
  7. pmc Analysis of the Rickettsia africae genome reveals that virulence acquisition in Rickettsia species may be explained by genome reduction
    Pierre Edouard Fournier
    Unite des Rickettsies, IFR 48 CNRS UMR 6020, Faculte de Medecine, Universite de la Mediterranee, 27 Boulevard Jean Moulin, Marseille Cedex 05, France
    BMC Genomics 10:166. 2009
  8. ncbi request reprint Evidence for louse-transmitted diseases in soldiers of Napoleon's Grand Army in Vilnius
    Didier Raoult
    Unite des Rickettsies, Centre National de la Recherche Scientifique CNRS Unite Mixte de Recherche UMR 6020, Universite de la Mediterranee, Faculte de Medecine, Marseille, France
    J Infect Dis 193:112-20. 2006
  9. pmc Rapid comparative genomic analysis for clinical microbiology: the Francisella tularensis paradigm
    Bernard La Scola
    Unite des Rickettsies CNRS UMR 6020, IFR 48, Faculte de Medecine de Marseille, Universite de la Mediterranee, 13385 Marseille Cedex 05, France
    Genome Res 18:742-50. 2008
  10. doi request reprint Soluble squalamine tablets for the rapid disinfection of home nebulizers of cystic fibrosis patients
    Lamia Djouhri-Bouktab
    Unité de Recherche des Maladies Infectieuses et Tropicales Emergentes UMR 6236 CNRS Méditerranée Infection, Faculte de Medecine et de Pharmacie, Aix Marseille Universite, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France
    J Cyst Fibros 11:555-9. 2012

Detail Information

Publications150 found, 100 shown here

  1. ncbi request reprint Molecular identification of a collection of spotted Fever group rickettsiae obtained from patients and ticks from Russia
    Stanislav N Shpynov
    Unite des Rickettsies, Faculte de Medecine, Marseille, France
    Am J Trop Med Hyg 74:440-3. 2006
    ..Clinicians should be aware that several spotted fever rickettsioses with different prognoses coexist in Russia in areas where NATT was the only previously recognized rickettsiosis...
  2. pmc Tropheryma whipplei Twist: a human pathogenic Actinobacteria with a reduced genome
    Didier Raoult
    Unite des Rickettsies, Faculte de Medecine, CNRS UMR6020, Universite de la Mediterranee, 13385 Marseille Cedex 05, France
    Genome Res 13:1800-9. 2003
    ..The analysis of the genome sequence of this previously largely unknown human pathogen is now guiding the development of molecular diagnostic tools and more convenient culture conditions...
  3. ncbi request reprint Molecular genetic methods for the diagnosis of fastidious microorganisms
    Florence Fenollar
    Unite des Rickettsies, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    APMIS 112:785-807. 2004
    ..Ehrlichia spp., Coxiella burnetii, Bartonella spp., Tropheryma whipplei and Yersinia pestis...
  4. ncbi request reprint rpoB gene sequence-based characterization of emerging non-tuberculous mycobacteria with descriptions of Mycobacterium bolletii sp. nov., Mycobacterium phocaicum sp. nov. and Mycobacterium aubagnense sp. nov
    Toidi Adekambi
    Unite des Rickettsies, CNRS UMR 6020 IFR 48, Faculte de Medecine, 27, Boulevard Jean Moulin, Université de la Méditerranée and Assistance Publique Hôpitaux de Marseille Timone, Fédération de Microbiologie Clinique, Marseille, France
    Int J Syst Evol Microbiol 56:133-43. 2006
    ....
  5. ncbi request reprint Rickettsia tamurae sp. nov., isolated from Amblyomma testudinarium ticks
    Pierre Edouard Fournier
    Unite des Rickettsies, IFR 48, CNRS UMR 6020, Faculte de Medecine, Universite de la Mediterranee, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France
    Int J Syst Evol Microbiol 56:1673-5. 2006
    ..Such genotypic and phenotypic characteristics warrant its classification as a representative of a novel species, for which the name Rickettsia tamurae sp. nov. is proposed, with the type strain AT-1(T) (=CSUR R1(T))...
  6. pmc Genomic analysis of an emerging multiresistant Staphylococcus aureus strain rapidly spreading in cystic fibrosis patients revealed the presence of an antibiotic inducible bacteriophage
    Jean Marc Rolain
    URMITE CNRS IRD UMR 6236, Faculte de Medecine et de Pharmacie, Universite de la Mediterranee, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France
    Biol Direct 4:1. 2009
    ..We also conducted a retrospective epidemiological analysis on all S. aureus isolated from 2002 to 2007 in CF patients from our institution...
  7. pmc Analysis of the Rickettsia africae genome reveals that virulence acquisition in Rickettsia species may be explained by genome reduction
    Pierre Edouard Fournier
    Unite des Rickettsies, IFR 48 CNRS UMR 6020, Faculte de Medecine, Universite de la Mediterranee, 27 Boulevard Jean Moulin, Marseille Cedex 05, France
    BMC Genomics 10:166. 2009
    ..prowazekii, which causes epidemic typhus and kills its arthropod host, to the mild pathogen R. africae, the agent of African tick-bite fever, which does not affect the fitness of its tick vector...
  8. ncbi request reprint Evidence for louse-transmitted diseases in soldiers of Napoleon's Grand Army in Vilnius
    Didier Raoult
    Unite des Rickettsies, Centre National de la Recherche Scientifique CNRS Unite Mixte de Recherche UMR 6020, Universite de la Mediterranee, Faculte de Medecine, Marseille, France
    J Infect Dis 193:112-20. 2006
    ..Because soldiers were commonly infested with body lice, it has been speculated that louse-borne infectious diseases, such as epidemic typhus (caused by Rickettsia prowazekii), were common...
  9. pmc Rapid comparative genomic analysis for clinical microbiology: the Francisella tularensis paradigm
    Bernard La Scola
    Unite des Rickettsies CNRS UMR 6020, IFR 48, Faculte de Medecine de Marseille, Universite de la Mediterranee, 13385 Marseille Cedex 05, France
    Genome Res 18:742-50. 2008
    ..In the bioterrorism context, it allows the rapid detection of strain manipulation, including intentionally added virulence genes and genes that support antibiotic resistance...
  10. doi request reprint Soluble squalamine tablets for the rapid disinfection of home nebulizers of cystic fibrosis patients
    Lamia Djouhri-Bouktab
    Unité de Recherche des Maladies Infectieuses et Tropicales Emergentes UMR 6236 CNRS Méditerranée Infection, Faculte de Medecine et de Pharmacie, Aix Marseille Universite, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France
    J Cyst Fibros 11:555-9. 2012
    ..The bacterial contamination of nebulizers represents a major problem for cystic fibrosis (CF) patients that can lead to reduced nebulizer performance and increase the risk of patient reinfection by the contaminating bacteria...
  11. pmc Multispacer typing to study the genotypic distribution of Bartonella henselae populations
    Wenjun Li
    Unite des Rickettsies, IFR 48, CNRS UMR 6020, Faculte de Medecine, Universite de la Mediterranee, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France
    J Clin Microbiol 44:2499-506. 2006
    ..Finally, we provide a free-access MST-Rick online software program (http://ifr48.timone.univ-mrs.fr/MST_BHenselae/mst) that investigators may use to compare their own MST sequences to our database...
  12. pmc Persistent Coxiella burnetii infection in mice overexpressing IL-10: an efficient model for chronic Q fever pathogenesis
    Soraya Meghari
    Unite des Rickettsies, CNRS UMR 6020, Institut Federatif de Recherche 48, Universite de la Mediterranee, Faculte de Medecine, Marseille, France
    PLoS Pathog 4:e23. 2008
    ..To our knowledge, this is the first efficient model for chronic Q fever pathogenesis...
  13. ncbi request reprint Molecular detection of Bartonella spp. in the dental pulp of stray cats buried for a year
    Gerard Aboudharam
    Unite des Rickettsies, CNRS UMR 6020, IFR 48, Faculte de Medecine, Universite de la Mediterranee, 27, Boulevard Jean Moulin, Marseille Cedex 05 13385, France
    Microb Pathog 38:47-51. 2005
    ..grahamii (one cat). Our study indicates that dental pulp from the teeth of cats, especially the canine teeth, may be used for the PCR detection of Bartonella in animals buried for a year...
  14. pmc Outbreak of Corynebacterium pseudodiphtheriticum infection in cystic fibrosis patients, France
    Fadi Bittar
    Universite de la Mediterranee, Marseille, France
    Emerg Infect Dis 16:1231-6. 2010
    ..Our study reemphasizes the conclusion that correctly identifying bacteria at the species level facilitates detection of an outbreak of new or emerging infections in humans...
  15. doi request reprint Investigation of blood culture-negative early prosthetic valve endocarditis reveals high prevalence of fungi
    Franck Thuny
    Unite de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, CNRS IRD UMR 6236, Faculte de Medecine, Universite de la Mediterranee, 27 Blvd Jean Moulin, 13385 Marseille Cedex 05, France
    Heart 96:743-7. 2010
    ..Therefore, fungi should be investigated particularly by molecular methods on surgical specimens and an antifungal drug might be added to the empiric treatment...
  16. ncbi request reprint The 1.2-megabase genome sequence of Mimivirus
    Didier Raoult
    Unite des Rickettsies, Faculte de Medecine, CNRS UMR6020, Universite de la Mediterranee, 13385 Marseille Cedex 05, France
    Science 306:1344-50. 2004
    ..This new sequence data might help shed a new light on the origin of DNA viruses and their role in the early evolution of eukaryotes...
  17. pmc Genotyping, Orientalis-like Yersinia pestis, and plague pandemics
    Michel Drancourt
    Universite de la Mediterranee, Marseille, France
    Emerg Infect Dis 10:1585-92. 2004
    ..pestis Orientalis. These data indicate that Y. pestis caused cases of Justinian plague. The two historical plague pandemics were likely caused by Orientalis-like strains...
  18. pmc The transcriptional programme of human heart valves reveals the natural history of infective endocarditis
    Marie Benoit
    Unité de Recherche sur les Maladies Infectieuses Transmissibles et Emergentes, Faculte de Medecine, Centre National de la Recherche Scientifique Unité Mixte de Recherche 6236, Universite de la Mediterranee, Marseille, France
    PLoS ONE 5:e8939. 2010
    ..Some parameters identified in this work could become tools for measuring the disease activity and should be tested as biomarkers for diagnosis or prognosis assessment in future studies...
  19. doi request reprint MALDI-TOF-mass spectrometry applications in clinical microbiology
    Piseth Seng
    Pôle des Maladies Infectieuses, Assistance Publique Hôpitaux de Marseille et URMITE UMR CNRS IRD 6236, IFR48, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    Future Microbiol 5:1733-54. 2010
    ..We will also discuss the application of MALDI-TOF-MS tools in the identification of Archaea, eukaryotes and viruses. Pathogenic identification from colony-cultured, blood-cultured, urine and environmental samples is also reviewed...
  20. ncbi request reprint A murine model of infection with Rickettsia prowazekii: implications for pathogenesis of epidemic typhus
    Yassina Bechah
    Unite des Rickettsies, CNRS UMR 6020, Universite de la Mediterranee, Faculte de Medecine, 27 Bld J Moulin, 13385 Marseille Cedex 05, France
    Microbes Infect 9:898-906. 2007
    ..We concluded that the BALB/c mouse strain provides a useful model for studying the pathogenic mechanisms of epidemic typhus and its control by the immune system...
  21. pmc Nanobacteria are mineralo fetuin complexes
    Didier Raoult
    Unite des Rickettsies, Centre National de la Recherche Scientifique UMR 6020, IFR 48, Faculte de Medecine, Marseille, France
    PLoS Pathog 4:e41. 2008
    ..The presence of fetuin within renal calculi was also evidenced, suggesting its role as a hydroxyapatite nucleating factor...
  22. ncbi request reprint Identification of two putative rickettsial adhesins by proteomic analysis
    Patricia Renesto
    Unite des Rickettsies, CNRS UMR 6020, IFR 48, Faculte de Medecine, 27 Boulevard Jean Moulin, 13385 Marseille, France
    Res Microbiol 157:605-12. 2006
    ..Both proteins are highly conserved within the Rickettsia genus and might play a critical role in their pathogenicity. These data may have important implications for the development of future vaccines against rickettsial infections...
  23. pmc Rickettsia conorii transcriptional response within inoculation eschar
    Patricia Renesto
    Unite des Rickettsies, IRD CNRS UMR 6236, Faculte de Medecine, Marseille, France
    PLoS ONE 3:e3681. 2008
    ..The skin thus constitutes an important barrier for the entry and propagation of R. conorii. Given this, analysis of the survival strategies used by the bacterium within infected skin is critical for our understanding of rickettsiosis...
  24. pmc Detection of a rickettsia closely related to Rickettsia aeschlimannii, "Rickettsia heilongjiangensis," Rickettsia sp. strain RpA4, and Ehrlichia muris in ticks collected in Russia and Kazakhstan
    Stanislav Shpynov
    Unite des Rickettsies, IFR48, CNRS UMR 6020, Faculte de Medecine, Universite de la Mediterranee, 13385 Marseille Cedex 5, France
    J Clin Microbiol 42:2221-3. 2004
    ..In Kazakhstan, we detected Rickettsia sp. strain RpA4 and a rickettsia closely related to Rickettsia aeschlimannii. These agents should be considered in a differential diagnosis of tick-borne infections in these areas...
  25. ncbi request reprint Emended description of Rickettsia felis (Bouyer et al. 2001), a temperature-dependent cultured bacterium
    Bernard La Scola
    Unite des Rickettsies, CNRS UPRESA 6020, Faculte de Medecine, Universite de la Mediterranee, 27 Bd Jean Moulin, 13385 Marseille 05, France
    Int J Syst Evol Microbiol 52:2035-41. 2002
    ..felis and those observed for the isolate in this study indicated some differences, although concurrent analysis of the two was not possible as no extant isolates of the first isolate of R. felis exist...
  26. ncbi request reprint Lipopolysaccharide from Coxiella burnetii is involved in bacterial phagocytosis, filamentous actin reorganization, and inflammatory responses through Toll-like receptor 4
    Amélie Honstettre
    Unite des Rickettsies, Centre National de la Recherche Scientifique Unité Mixte de Recherche 6020, Institut Federatif de Recherche 48 Université de la Méditerranée, Marseille, France
    J Immunol 172:3695-703. 2004
    ..Taken together, these results demonstrate that TLR4 controls early events of C. burnetii infection such as macrophage phagocytosis, granuloma formation, and cytokine production...
  27. ncbi request reprint Coxiella burnetii stimulates production of RANTES and MCP-1 by mononuclear cells: modulation by adhesion to endothelial cells and its implication in Q fever
    Soraya Meghari
    Unite des Rickettsies, CNRS UMR 6020, Universite de la Mediterranee, Institut Federatif de Recherche 48, Faculte de Medecine, 27 Bd Jean Moulin, 13385 Marseille Cedex 5, France
    Eur Cytokine Netw 17:253-9. 2006
    ..We suggest that the overproduction of RANTES and MCP-1 secondary to the contact of PBMC with endothelium may perpetuate exaggerated inflammatory responses leading to inappropriate PBMC trafficking and to the pathogenesis of Q fever...
  28. pmc Yersinia pestis Orientalis in remains of ancient plague patients
    Michel Drancourt
    Universite de la Mediterranee, Marseille, France
    Emerg Infect Dis 13:332-3. 2007
    ..We have now sequenced Y pestis glpD gene in such remains, showing a 93-bp deletion specific for biotype Orientalis. These data show that only Orientalis type caused the 3 plague pandemics...
  29. doi request reprint Value of Tropheryma whipplei quantitative polymerase chain reaction assay for the diagnosis of Whipple disease: usefulness of saliva and stool specimens for first-line screening
    Florence Fenollar
    Unite des Rickettsies, Universite de la Mediterranee, Centre National de Recherche Scientifique, Marseille, France
    Clin Infect Dis 47:659-67. 2008
    ..Whipple disease (WD) is a chronic infectious disease caused by Tropheryma whipplei. WD DNA has been found in stool and saliva specimens from patients and asymptomatic carriers...
  30. doi request reprint Deleterious effect of ciprofloxacin on Rickettsia conorii-infected cells is linked to toxin-antitoxin module up-regulation
    Elisabeth Botelho-Nevers
    URMITE UMR 6236, CNRS IRD, Faculte de Medecine, 27 Bd Jean Moulin, 13385 Marseille Cedex 05, France
    J Antimicrob Chemother 67:1677-82. 2012
    ..To confirm and better understand the deleterious effect of fluoroquinolones reported during Rickettsia conorii infection in humans...
  31. pmc Tropheryma whipplei: a common bacterium in rural Senegal
    Alpha Kabinet Keita
    Unite de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, URMITE CNRS IRD 198 UMR 6236, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    PLoS Negl Trop Dis 5:e1403. 2011
    ....
  32. doi request reprint Intracellular life of Coxiella burnetii in macrophages
    Eric Ghigo
    URMITE CNRS UMR 6236 IRD 3R198, Institut Federatif de Recherche 48, Universite de la Mediterranee, Marseille, France
    Ann N Y Acad Sci 1166:55-66. 2009
    ..burnetii also depends on the functional state of myeloid cells. This review describes the mechanisms used by C. burnetii to circumvent uptake and trafficking events, and the role of cytokines on C. burnetii survival in myeloid cells...
  33. ncbi request reprint Isolation of a rickettsia related to Astrakhan fever rickettsia from a patient in Chad
    Pierre Edouard Fournier
    Unite des Rickettsies, IFR 48, CNRS UMR 6020, Faculte de Medecine, Universite de la Mediterranee, 13385 Marseilles Cedex 05, France
    Ann N Y Acad Sci 990:152-7. 2003
    ..Although Astrakhan fever rickettsia is transmitted by Rhipicephalus ticks in Europe, further studies are indicated to identify its vector in Africa where these ticks are also prevalent...
  34. pmc Lymph node biopsy specimens and diagnosis of cat-scratch disease
    Jean Marc Rolain
    Universite de la Mediterranee, Marseille, France
    Emerg Infect Dis 12:1338-44. 2006
    ..Histologic analysis of lymph node biopsy specimens should be routinely performed because some patients might have a concurrent malignant disease or mycobacteriosis...
  35. pmc Bartonella and Rickettsia in arthropods from the Lao PDR and from Borneo, Malaysia
    Tahar Kernif
    Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes URMITE, Universite de la Mediterranee, Marseille, France
    Comp Immunol Microbiol Infect Dis 35:51-7. 2012
    ..felis and B. clarridgeiae. Further investigations are needed in order to isolate these agents and to determine their epidemiology and aetiological role in unknown fever in patients from these areas...
  36. ncbi request reprint Bacteroides massiliensis sp. nov., isolated from blood culture of a newborn
    Lukas Fenner
    Unite des Rickettsies, CNRS UPRESA 6020, Faculte de Medecine, Universite de la Mediterrannee, Marseille, France
    Int J Syst Evol Microbiol 55:1335-7. 2005
    ..8 % 16S rRNA similarity to Bacteroides vulgatus and a DNA G + C content of 49 mol%. The major cellular fatty acid is anteiso-branched C(15 : 0). The type strain of B. massiliensis sp. nov. is B84634(T) (=CIP 107942(T) = CCUG 48901(T))...
  37. pmc Analysis of 525 samples to determine the usefulness of PCR amplification and sequencing of the 16S rRNA gene for diagnosis of bone and joint infections
    Florence Fenollar
    Unite des Rickettsies, CNRS UMR 6020, IFR 48, Faculte de Medecine, Universite de la Mediterranee, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France
    J Clin Microbiol 44:1018-28. 2006
    ..Seven organisms representing new potential species were also detected. PCR followed by cloning and sequencing may help to identify new pathogens involved in mixed bone infection...
  38. pmc Multispacer typing of Rickettsia prowazekii enabling epidemiological studies of epidemic typhus
    Yong Zhu
    Unite des Rickettsies, CNRS UMR 6020, IFR 48, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    J Clin Microbiol 43:4708-12. 2005
    ..This may help to discriminate between natural and intentional outbreaks. Our study supports the usefulness of MST as a versatile method for rickettsial strain genotyping...
  39. ncbi request reprint Whipple disease: intestinal infiltrating cells exhibit a transcriptional pattern of M2/alternatively activated macrophages
    Benoit Desnues
    Unite des Rickettsies, Centre National de la Recherche Scientifique, Institut Federatif de Recherche 48, Universite de la Mediterranee, Faculte de Medecine, Marseille, France
    J Infect Dis 192:1642-6. 2005
    ..This transcriptional pattern corresponds to that of M2/alternatively activated macrophages. Our results suggest that the T helper 2 response in the intestinal environment may account for the pathophysiological properties of WD...
  40. doi request reprint Detection of Acinetobacter baumannii in human head and body lice from Ethiopia and identification of new genotypes
    Marie Kempf
    URMITE, UMR IRD 198 CNRS 6236, Faculte de Medecine, 27 Bd Jean Moulin, 13385 Marseille Cedex 05, France
    Int J Infect Dis 16:e680-3. 2012
    ..The objectives of this study were to determine the presence of this bacterium in head and body lice collected from healthy individuals in Ethiopia by molecular methods and to characterize the genotype...
  41. ncbi request reprint Coxiella burnetii infection in C57BL/6 mice aged 1 or 14 months
    Marc Leone
    Unite des Rickettsies, Centre National de la Recherche Scientifique, Universite de la Mediterranee, Faculte de Medecine, Marseille, France
    FEMS Immunol Med Microbiol 50:396-400. 2007
    ..In addition, macrophage microbicidal competence was similar in mature and young mice. These results suggest the importance of individual host factors in the pathophysiology of an infectious disease such as Q fever...
  42. pmc Prevalence of Bartonella clarridgeiae and Bartonella henselae in domestic cats from France and detection of the organisms in erythrocytes by immunofluorescence
    Jean Marc Rolain
    Unité des Rickettsies CNRS UMR A 6020, IFR 48, Faculte de Medecine, Universite de la Mediterranee, 13385 Marseille Cedex 05, France
    Clin Diagn Lab Immunol 11:423-5. 2004
    ..1% (8 of 99 cats). The intraerythrocytic location of Bartonella clarridgeiae is shown for the first time, and we show that immunofluorescence detection of the organism in erythrocytes correlates with the number of bacteria in blood...
  43. doi request reprint Comprehensive diagnostic strategy for blood culture-negative endocarditis: a prospective study of 819 new cases
    Pierre Edouard Fournier
    Unite de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, Centre National de la Recherche Scientifique Institut de Recherche pour le Développement, Unite Mixte de Recherche 6236, Faculte de Medecine, Universite de la Mediterranee, France
    Clin Infect Dis 51:131-40. 2010
    ..whipplei, Bartonella species, and fungi in blood. Broad-spectrum 16S and 18S ribosomal RNA PCR may be performed on valvular biopsies, when available...
  44. pmc Looking for Tropheryma whipplei source and reservoir in rural Senegal
    Alpha Kabinet Keita
    Aix Marseille Universite, Unite des Rickettsies, Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes URMITE, UM63, CNRS 7278, IRD 198, INSERM 1095, 13005 Marseille, France
    Am J Trop Med Hyg 88:339-43. 2013
    ..Humans are currently the predominant identified reservoir and source of T. whipplei in these populations. Limited access to toilets and exposure to human feces facilitate the fecal-oral transmission of T. whipplei...
  45. doi request reprint Tentative characterization of new environmental giant viruses by MALDI-TOF mass spectrometry
    Bernard La Scola
    Pôle des Maladies Infectieuses, Assistance Publique Hôpitaux de Marseille and URMITE UMR CNRS IRD 6236, IFR48, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    Intervirology 53:344-53. 2010
    ..We attempted herein to isolate new Acanthamoeba-growing giant viruses from environmental samples...
  46. doi request reprint Heterogeneity of susceptibility to fluoroquinolones in Bartonella isolates from Australia reveals a natural mutation in gyrA
    Emmanouil Angelakis
    Unite des Rickettsies, CNRS UMR 6020, IFR 48, Faculté de Médecine et de Pharmacie Université de la Méditerranée, 27 Bd Jean Moulin, 13385 Marseille Cedex 05, France
    J Antimicrob Chemother 61:1252-5. 2008
    ..Our objective was to evaluate in vitro antibiotic susceptibilities of 20 new Bartonella isolates from animals in Australia...
  47. doi request reprint Actinomyces massiliensis sp. nov., isolated from a patient blood culture
    Aurelie Renvoise
    Laboratoire de Bacteriologie virologie, Hopital de la Timone, CNRS UMR 6236, CNRS IRD, IFR48, 264 rue Saint Pierre, 13385 Marseille Cedex 05, France
    Int J Syst Evol Microbiol 59:540-4. 2009
    ..On the basis of phenotypic data and phylogenetic inference, the novel species Actinomyces massiliensis sp. nov. is proposed; the type strain is 4401292(T) (=CSUR P18(T)=CCUG 53522(T))...
  48. doi request reprint Yersinia massiliensis sp. nov., isolated from fresh water
    Vicky Merhej
    AP HM Timone, Fédération de Microbiologie Clinique and Unité des Rickettsies CNRS UMR 6020, IFR 48, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    Int J Syst Evol Microbiol 58:779-84. 2008
    ..The name Yersinia massiliensis sp. nov. is proposed for this new taxon (type strain 50640T=CIP 109351T=CCUG 53443T; isolate 823=CIP 109352=CCUG 53444)...
  49. doi request reprint Gene repertoire of amoeba-associated giant viruses
    Philippe Colson
    URMITE UMR CNRS 6236 IRD 198, Facultes de Medecine et de Pharmacie, Universite de la Mediterranee, Marseille, France
    Intervirology 53:330-43. 2010
    ..Altogether, the data so far accumulated on amoeba-associated giant viruses are a powerful incentive to isolate and study additional strains to gain better understanding of their pangenome...
  50. ncbi request reprint A novel alpha-Proteobacterium, Nordella oligomobilis gen. nov., sp. nov., isolated by using amoebal co-cultures
    Bernard La Scola
    Unite des Rickettsies, CNRS UMR 6020, Faculte de Medecine, Universite de la Mediterrannee, 27, Boulevard Jean Moulin, 13385 Marseille Cedex 05, France
    Res Microbiol 155:47-51. 2004
    ..nov., sp. nov. The genus Nordella forms a well separated taxon in the order Rhizobiales within the alpha-2 subgroup of Proteobacteria. Its close relatives are environmental uncultured bacteria...
  51. pmc Murine model of infection by Tropheryma whipplei
    Sèverine Genot
    Unite des Rickettsies, CNRS UMR 6020, Faculte de Medecine, Universite de la Mediterranee, 27 bld Jean Moulin, 13385 Marseille Cedex 05, France
    Infect Immun 74:4915-7. 2006
    ..SCID mice were infected similarly but did not develop tissue lesions. The delayed clearance of T. whipplei suggests a protective role for innate immunity...
  52. ncbi request reprint Experimental infection models of ticks of the Rhipicephalus sanguineus group with Rickettsia conorii
    Koutaro Matsumoto
    Unite des Rickettsies, CNRS UMR 6020 IFR 48, Faculte de Medecine, Marseille, France
    Vector Borne Zoonotic Dis 5:363-72. 2005
    ..The harmful effect of R. conorii on Rh. sanguineus group ticks from Thailand is discussed including the role of the geographic origin of the ticks and the difficulties to identify ticks within this group to the species level...
  53. ncbi request reprint Development of a method for recovering rickettsial RNA from infected cells to analyze gene expression profiling of obligate intracellular bacteria
    My Van La
    Unite des Rickettsies, CNRS UMR6020, IFR48, Faculte de Medecine, 27, Bd Jean Moulin, Marseille, France
    J Microbiol Methods 71:292-7. 2007
    ..We conclude that this approach has great potential for the study of mechanisms behind the virulence and intracellular survival of members of the genus Rickettsia...
  54. pmc The uptake of apoptotic cells drives Coxiella burnetii replication and macrophage polarization: a model for Q fever endocarditis
    Marie Benoit
    Unité de Recherche sur les Maladies Infectieuses Transmissibles et Emergentes, CNRS UMR 6236, Institut Federatif de Recherche 48, Universite de la Mediterranee, Faculte de Medecine, Marseille, France
    PLoS Pathog 4:e1000066. 2008
    ..burnetii. We suggest that leukocyte apoptosis associated with valvulopathy may be critical for the pathogenesis of Q fever endocarditis by deactivating immune cells and creating a favorable environment for bacterial persistence...
  55. pmc Immuno-PCR--a new tool for paleomicrobiology: the plague paradigm
    Nada Malou
    Aix Marseille Universite, URMITE, UMR CNRS 6236 IRD 198, Faculte de Medecine, Marseille, France
    PLoS ONE 7:e31744. 2012
    ..However, the degradation of DNA limits the ability to detect ancient infections...
  56. ncbi request reprint Yersinia pestis as a telluric, human ectoparasite-borne organism
    Michel Drancourt
    Unite des Rickettsies CNRS UMR 6020, IRF 48, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    Lancet Infect Dis 6:234-41. 2006
    ..If confirmed, these data should be taken into account to update public-health policies and bioterrorism risk management, particularly among ectoparasite-infested people...
  57. pmc Proposal to create subspecies of Rickettsia conorii based on multi-locus sequence typing and an emended description of Rickettsia conorii
    Yong Zhu
    Unite des Rickettsies, IFR 48, CNRS UMR 6020, Faculte de Medecine, Universite de la Mediterranee, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France
    BMC Microbiol 5:11. 2005
    ..Then, we selected a representative of each MLST genotype and used multi-spacer typing (MST) and mouse serotyping to estimate their degree of taxonomic relatedness...
  58. ncbi request reprint Cardiac valves in patients with Whipple endocarditis: microbiological, molecular, quantitative histologic, and immunohistochemical studies of 5 patients
    Hubert Lepidi
    Unite des Rickettsies, Centre National de la Recherche Scientifique, Unite de Mixte de Recherche 6020, Institut Federatif Recherche 48, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    J Infect Dis 190:935-45. 2004
    ..We report, for the first time, the immunodetection of T. whipplei in a surgically removed arterial embolus. Pathological and immunohistologic analyses may contribute to the diagnosis of Whipple endocarditis...
  59. ncbi request reprint Molecular detection of Bartonella henselae DNA in the dental pulp of 800-year-old French cats
    Vu Dang La
    Unite des Rickettsies, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    Clin Infect Dis 39:1391-4. 2004
    ..We conclude that cats had bacteremia due to B. henselae 800 years ago...
  60. pmc Description of Mycobacterium conceptionense sp. nov., a Mycobacterium fortuitum group organism isolated from a posttraumatic osteitis inflammation
    Toidi Adekambi
    Unite des Rickettsies, Faculte de Medecine, 27, Boulevard Jean Moulin, 13385 Marseille Cedex 05, France
    J Clin Microbiol 44:1268-73. 2006
    ..porcinum. We propose the name Mycobacterium conceptionense sp. nov. for this new species associated with posttraumatic osteitis. The type strain is D16(T) (equivalent to CIP 108544(T) and CCUG 50187(T))...
  61. pmc Tropheryma whipplei in children with gastroenteritis
    Didier Raoult
    Universite de la Mediterranee, Marseille, France
    Emerg Infect Dis 16:776-82. 2010
    ..002). High incidence in patients and evidence of clonal circulation suggests that some cases of gastroenteritis are caused or exacerbated by T. whipplei, which may be co-transmitted with other intestinal pathogens...
  62. doi request reprint Paenibacillus provencensis sp. nov., isolated from human cerebrospinal fluid, and Paenibacillus urinalis sp. nov., isolated from human urine
    Veronique Roux
    Laboratoire de Bacteriologie virologie, Hopital de la Timone, CNRS UMR 6020, IFR48, 264 rue Saint Pierre, 13385 Marseille Cedex 05, France
    Int J Syst Evol Microbiol 58:682-7. 2008
    ..nov. (type strain 5402403(T) =CIP 109357(T) =CCUG 53521(T)) and Paenibacillus provencensis sp. nov. (type strain 4401170(T) =CIP 109358(T) =CCUG 53519(T))...
  63. doi request reprint The effect of a single dose of oral ivermectin on pruritus in the homeless
    Sekene Badiaga
    Unite des Rickettsies, CNRS UMR 6020, IFR 48, Faculte de Medecine, 13185 Marseille, France
    J Antimicrob Chemother 62:404-9. 2008
    ..Homeless people commonly present with ectoparasite-based pruritus. We evaluated the efficacy of a single dose of ivermectin to reduce the pruritus prevalence in a homeless population...
  64. pmc Altitude-dependent Bartonella quintana genotype C in head lice, Ethiopia
    Emmanouil Angelakis
    Universite de la Mediterranee, Marseille, France
    Emerg Infect Dis 17:2357-9. 2011
    ..B. quintana was found in 19 (7%) genotype C head lice and in 76 (18%) genotype A body lice. B. quintana in head lice was positively linked to altitude (p = 0.014)...
  65. doi request reprint The virophage as a unique parasite of the giant mimivirus
    Bernard La Scola
    URMITE, Centre National de la Recherche Scientifique UMR IRD 6236, Faculte de Medecine, Universite de la Mediterranee, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 5, France
    Nature 455:100-4. 2008
    ..Considering its functional analogy with bacteriophages, we classify this virus as a virophage. The virophage could be a vehicle mediating lateral gene transfer between giant viruses...
  66. pmc The giant Cafeteria roenbergensis virus that infects a widespread marine phagocytic protist is a new member of the fourth domain of Life
    Philippe Colson
    Centre National de la Recherche Scientifique Unité Mixte de Recherche 6236, Institut de Recherche pour le Développement 3R198, Facultes de Medecine et de Pharmacie, Universite de la Mediterranee, Marseille, France
    PLoS ONE 6:e18935. 2011
    ..Recently, the genome of a new NCLDV, Cafeteria roenbergensis virus (CroV), was released. The present work aimed to determine if CroV supports the fourth domain of Life hypothesis...
  67. doi request reprint Tropheryma whipplei glycosylation in the pathophysiologic profile of Whipple's disease
    Cyrille J Bonhomme
    Unite des Rickettsies, Centre National de la Recherche Scientifique 6236, Universite de la Mediterranee, Marseille, France
    J Infect Dis 199:1043-52. 2009
    ..Tropheryma whipplei is a bacterium commonly found in people with Whipple's disease, a rare systemic chronic infection. In the present study, we hypothesized that bacterium glycosylation may impair the immune response...
  68. pmc False positive PCR detection of Tropheryma whipplei in the saliva of healthy people
    Jean Marc Rolain
    Universite de la Mediterranee, Unite des Rickettsies, CNRS UMR 6020, IFR 48, Faculte de Medecine, Marseille Cedex 05, France
    BMC Microbiol 7:48. 2007
    ..whipplei in a series of 57 saliva from healthy people...
  69. doi request reprint Prevalence of asymptomatic Tropheryma whipplei carriage among humans and nonhuman primates
    Florence Fenollar
    Universite de la Mediterranee, Unite des Rickettsies, CNRS UMR 6020, Faculte de Medecine, Marseille Cedex, France
    J Infect Dis 197:880-7. 2008
    ..The reservoir of the agent of Whipple disease is unknown. Asymptomatic carriage of Tropheryma whipplei in human stool and saliva is controversial...
  70. ncbi request reprint Legionella drancourtii sp. nov., a strictly intracellular amoebal pathogen
    Bernard La Scola
    Unite des Rickettsies, CNRS UPRESA 6020, Faculte de Medecine, Universite de la Mediterrannee, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France
    Int J Syst Evol Microbiol 54:699-703. 2004
    ..Taken together, these results support the proposal of LLAP12(T) as the type strain of Legionella drancourtii sp. nov...
  71. doi request reprint Bacterial strain typing in the genomic era
    Wenjun Li
    Unité des Rickettsies et pathogènes émergents, CNRS UMR 6236, IRD 198, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    FEMS Microbiol Rev 33:892-916. 2009
    ....
  72. doi request reprint Tropheryma whipplei bacteremia during fever in rural West Africa
    Florence Fenollar
    Unite de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, Universite de la Mediterranee, Faculte de Medecine, 1Marseille, France
    Clin Infect Dis 51:515-21. 2010
    ..We investigated the role of T. whipplei in febrile patients from rural Senegal who had a negative test result for malaria...
  73. pmc Sca1, a previously undescribed paralog from autotransporter protein-encoding genes in Rickettsia species
    Maxime Ngwamidiba
    Unite des Rickettsies, IFR 48, CNRS UMR 6020, Faculte de Medecine, Universite de la Mediterranee, 13385 Marseille Cedex 05, France
    BMC Microbiol 6:12. 2006
    ....
  74. doi request reprint rpoB sequence-based identification of Mycobacterium avium complex species
    Iskandar Ben Salah
    Unite de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, UMR, CNRS IRD 6236, IFR 48 Faculté de Médecine, Universite de la Mediterranee, Marseille, France
    Microbiology 154:3715-23. 2008
    ..Partial rpoB gene sequencing using the Myco-F/Myco-R primers permits one-step identification of MAC isolates at the species level and the detection of potentially novel MAC species...
  75. pmc Ultrastructural characterization of the giant volcano-like virus factory of Acanthamoeba polyphaga Mimivirus
    Marie Suzan-Monti
    Unite des Rickettsies, Centre National de la Recherche Scientifique CNRS UMR 6020, IFR 48, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    PLoS ONE 2:e328. 2007
    ....
  76. ncbi request reprint Proteome analysis of Rickettsia conorii by two-dimensional gel electrophoresis coupled with mass spectrometry
    Patricia Renesto
    Unite des Rickettsies, CNRS UMR 6020, IFR 48, Faculte de Medecine, 27 Boulevard Jean Moulin, 13385 Marseille, France
    FEMS Microbiol Lett 245:231-8. 2005
    ..conorii, to compare protein profiles of different isolates or of bacteria maintained under different experimental conditions and to identify immunogenic proteins as potential vaccine targets...
  77. pmc Identification of rickettsial isolates at the species level using multi-spacer typing
    Pierre Edouard Fournier
    Unite des Rickettsies, IFR 48, CNRS UMR 6020, Faculte de Medecine, Universite de la Mediterranee, Marseille Cedex 05, France
    BMC Microbiol 7:72. 2007
    ....
  78. ncbi request reprint Corpuscular antigenic microarray for the serodiagnosis of blood culture-negative endocarditis
    Laurent Samson
    Unite des Rickettsies, CNRS UMR 6020, IFR 48, Faculte de Medecine, Universite de la Mediterranee, 27 Bd Jean Moulin, 13385 Marseille Cedex 05, France
    Ann N Y Acad Sci 1078:595-6. 2006
    ..Preliminary results indicate that this new serologic test is valuable for the rapid, automated serological diagnosis of blood culture-negative endocarditis...
  79. ncbi request reprint Experimental model to evaluate the human body louse as a vector of plague
    Linda Houhamdi
    Unite des Rickettsies, Institut Federatif de Recherche 48, Centre National de Recherche Scientifique, Unite Mixte de Recherche 6020, Universite de la Mediterranee, Marseille Cedex 5 13385, France
    J Infect Dis 194:1589-96. 2006
    ..Infections were transmitted to naive lice that were fed on these rabbits, showing that lice can be vectors of Y. pestis in an experimental model...
  80. pmc Genotyping of human lice suggests multiple emergencies of body lice from local head louse populations
    Wenjun Li
    URMITE, UMR CNRS 6236, IRD 198, Universite de la Mediterranee, Faculte de Medecine, Marseille, France
    PLoS Negl Trop Dis 4:e641. 2010
    ..Recent studies suggest that body lice arose several times from head louse populations...
  81. doi request reprint Genotyping reveals a wide heterogeneity of Tropheryma whipplei
    Wenjun Li
    Unite des Rickettsies, IFR 48, CNRS UMR 6020, Faculte de Medecine, Universite de la Mediterranee, Marseille Cedex 05, France
    Microbiology 154:521-7. 2008
    ..whipplei strains that is apparently independent of geographical distribution and unrelated to bacterial pathogenicity. Genotyping in Whipple's disease may, however, be useful in epidemiological studies...
  82. pmc Molecular detection of multiple emerging pathogens in sputa from cystic fibrosis patients
    Fadi Bittar
    Unite de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, CNRS IRD, UMR 6236, Faculte de Medecine et de Pharmacie, Universite de la Mediterranee, Marseille, France
    PLoS ONE 3:e2908. 2008
    ..There is strong evidence that culture-based methods detect only a small proportion of bacteria present in the respiratory tracts of cystic fibrosis (CF) patients...
  83. ncbi request reprint Rickettsia conorii and R. prowazekii proteome analysis by 2DE-MS: a step toward functional analysis of rickettsial genomes
    Patricia Renesto
    Unite des Rickettsies, CNRS UMR 6020, Marseille, France
    Ann N Y Acad Sci 1063:90-3. 2005
    ..This analysis reveals protein spots that were either unique to or common to both strains, some of them being identified by matrix-assisted laser desorption ionization-time of flight mass spectrometry...
  84. doi request reprint Validation of partial rpoB gene sequence analysis for the identification of clinically important and emerging Acinetobacter species
    Vijay A K B Gundi
    Unite des Rickettsies, CNRS UMR 6236, Faculte de Medecine de Marseille, 13385 Marseille Cedex 05, France
    Microbiology 155:2333-41. 2009
    ..Our data emphasize the recognition of A. schindleri as an emerging cause of Acinetobacter-related infection and confirm that A. gen. sp. 3 is the second most commonly isolated Acinetobacter species after A. baumannii in patients...
  85. pmc Monitoring bacterial community of human gut microbiota reveals an increase in Lactobacillus in obese patients and Methanogens in anorexic patients
    Fabrice Armougom
    URMITE UMR CNRS 6236, IRD 3R198, Universite de la Mediterranee, Faculte de Medecine, and Nutrition and Diabetology Department, University Hospital Sainte Marguerite, Marseille, France
    PLoS ONE 4:e7125. 2009
    ..The roles of the archaeon Methanobrevibacter smithii and Lactobacillus species have not been described in these studies...
  86. pmc Genetic identification of rickettsiae isolated from ticks in Japan
    Pierre Edouard Fournier
    Unite des Rickettsies, Faculte de Medecine, CNRS UMR 6020 27, Universite de la Mediterranee, 13385 Marseille, Cedex 05, France
    J Clin Microbiol 40:2176-81. 2002
    ..Finally, we identified a new genotype of unknown pathogenicity, genotype AT, that was isolated from Amblyomma testudinarium ticks and that is closely related to a Slovakian genotype obtained from Ixodes ricinus ticks...
  87. pmc Gene sequence-based criteria for identification of new rickettsia isolates and description of Rickettsia heilongjiangensis sp. nov
    Pierre Edouard Fournier
    Unite des Rickettsies, IFR 48, CNRS UMR 6020, Faculte de Medecine, Universite de la Mediterranee, 13385 Marseille Cedex 05, France
    J Clin Microbiol 41:5456-65. 2003
    ..3% for the ompA and ompB genes and gene D, respectively. By use of our classification scheme, "Rickettsia heilongjiangii" belongs to a new species for which we officially propose the name Rickettsia heilongjiangensis sp. nov...
  88. doi request reprint Q Fever
    Emmanouil Angelakis
    Unite des Rickettsies, CNRS UMR 6020, IFR 48, Faculte de Medecine, Université de Méditerranée, 27 Bd Jean Moulin, 13385 Marseille Cedex 05, France
    Vet Microbiol 140:297-309. 2010
    ..Vaccination of animals in infected flocks, as well as in uninfected ones close to them, with an efficient vaccine can prevent abortions and shedding of the bacteria...
  89. ncbi request reprint Blood culture-negative endocarditis in a reference center: etiologic diagnosis of 348 cases
    Pierre Houpikian
    Unitué des Rickettsies, Universite de la Mediterranee, Faculte de Medecine, CNRS UPRES A 6020, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France
    Medicine (Baltimore) 84:162-73. 2005
    ..Further investigations should be focused on this group to identify new agents of infective endocarditis...
  90. ncbi request reprint Bosea eneae sp. nov., Bosea massiliensis sp. nov. and Bosea vestrisii sp. nov., isolated from hospital water supplies, and emendation of the genus Bosea (Das et al. 1996)
    Bernard La Scola
    Unite des Rickettsies, CNRS UPRESA 6020, Faculte de Medecine, Universite de la Mediterrannee, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France
    Int J Syst Evol Microbiol 53:15-20. 2003
    ..For treatment of infections caused by these novel bacteria, doxycycline appears to be the sole antibacterial compound with a consistently low MIC value...
  91. ncbi request reprint Bacillus massiliensis sp. nov., isolated from cerebrospinal fluid
    Olga O Glazunova
    Laboratoire de Bacteriologie virologie, Hopital de la Timone, CNRS UMR 6020, IFR48, 264 rue Saint Pierre, 13385 Marseille Cedex 05, France
    Int J Syst Evol Microbiol 56:1485-8. 2006
    ..The major fatty acid was iso-C(15 : 0) (48 %). The name Bacillus massiliensis sp. nov. is proposed for the novel isolate, with strain 4400831(T) (=CIP 108446(T)=CCUG 49529(T)) as the type strain...
  92. pmc Value of microimmunofluorescence for diagnosis and follow-up of Bartonella endocarditis
    Pierre Edouard Fournier
    Unite des Rickettsies, IFR 48 CNRS, UMR 6020 Université de la Méditerranée, Faculte de Medecine, 13385 Marseille Cedex 05, France
    Clin Diagn Lab Immunol 9:795-801. 2002
    ..We propose that this criterion, which may also help with the detection of late relapses, be included as a major criterion in the Duke criteria for the diagnosis of infective endocarditis...
  93. ncbi request reprint Bartonella quintana in a 4000-year-old human tooth
    Michel Drancourt
    Unite des Rickettsies, CNR UMR 6020, IFR 48, Marseille, France
    J Infect Dis 191:607-11. 2005
    ..Humans are the reservoir of B. quintana, the louse-borne agent of trench fever. We detected DNA of B. quintana in the dental pulp of a person who died 4000 years ago...
  94. doi request reprint The rpoB gene as a tool for clinical microbiologists
    Toidi Adekambi
    Unite de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, CNRS IRD UMR 6236 IFR 48, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    Trends Microbiol 17:37-45. 2009
    ..New identification tools targeting a rpoB gene fragment located between positions 2300 and 3300 have been developed recently. Therefore, inclusion of the rpoB gene sequence would be useful when describing new bacterial species...
  95. pmc Comparison between rpoB and 16S rRNA gene sequencing for molecular identification of 168 clinical isolates of Corynebacterium
    Atieh Khamis
    Unite des Rickettsies, CNRS UMR 6020, IFR 48, Faculte de Medecine, Universite de la Mediterrannee, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France
    J Clin Microbiol 43:1934-6. 2005
    ..This method is thus a simple, molecular-analysis-based method for identification of corynebacteria, but it should be used in conjunction with other tests for definitive identification...
  96. pmc Correlation between ratio of serum doxycycline concentration to MIC and rapid decline of antibody levels during treatment of Q fever endocarditis
    Jean Marc Rolain
    Unite des Rickettsies, CNRS UMR 6020, IFR 48, Faculte de Medecine, Universite de la Mediterranee, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France
    Antimicrob Agents Chemother 49:2673-6. 2005
    ..burnetii cultured from this patient was resistant to doxycycline (MIC = 8 microg/ml). The ratio of serum doxycycline concentration to MIC should be monitored during the course of therapy in patients with Q fever endocarditis...
  97. pmc Global transcriptome analysis of Tropheryma whipplei in response to temperature stresses
    Nicolas Crapoulet
    Unite des Rickettsies, CNRS UMR6020, IFR48, Faculte de Medecine, 27, Boulevard Jean Moulin, 13385 Marseille, France
    J Bacteriol 188:5228-39. 2006
    ..whipplei exhibits an adaptive response to thermal stresses which is consistent with its specific environmental origin and could allow survival under cold conditions...
  98. pmc Amoebal coculture of "Mycobacterium massiliense" sp. nov. from the sputum of a patient with hemoptoic pneumonia
    Toidi Adekambi
    Unite des Rickettsies, CNRS UMR 6020 IFR 48, Faculte de Medecine, Université de la Méditteranée, Marseille, France
    J Clin Microbiol 42:5493-501. 2004
    ..The type strain has been deposited in the Collection Institut Pasteur as CIP 108297(T) and in Culture Collection of the University of Goteborg, Goteborg, Sweden, as CCUG 48898(T)...
  99. doi request reprint A bioinformatic approach to understanding antibiotic resistance in intracellular bacteria through whole genome analysis
    Silpak Biswas
    URMITE UMR 6236, CNRS IRD, Faculte de Medecine et de Pharmacie, Universite de la Mediterranee, 27 Bd Jean Moulin, 13385 Marseille Cedex 05, France
    Int J Antimicrob Agents 32:207-20. 2008
    ..In the future, stable mutants should be obtained through transformation methods in order to demonstrate experimentally the determinants of resistance in intracellular bacteria...
  100. doi request reprint Regulation of whole bacterial pathogen transcription within infected hosts
    My Van La
    Unite des Rickettsies, Faculte de Medecine, 27 Boulevard Jean Moulin, Marseille, France
    FEMS Microbiol Rev 32:440-60. 2008
    ....
  101. ncbi request reprint Phylogenetic classification of Bartonella species by comparing groEL sequences
    Zaher Zeaiter
    Unite des Rickettsies, CNRS UPRES A 6020, Faculte de Medecine, Marseille, France
    Int J Syst Evol Microbiol 52:165-71. 2002
    ..In addition, the groEL gene was shown to be useful in subtyping six B. henselae isolates into three variants: Houston, Marseille and Fizz...