Julien Praline

Summary

Country: France

Publications

  1. doi request reprint Study of the HFE gene common polymorphisms in French patients with sporadic amyotrophic lateral sclerosis
    Julien Praline
    UMR Inserm U930, Universite Francois Rabelais, Tours, France Centre SLA, Service de Neurologie et Neurophysiologie Clinique, CHRU de Tours, France
    J Neurol Sci 317:58-61. 2012
  2. doi request reprint Co-occurrence of progressive anarthria with an S393L TARDBP mutation and ALS within a family
    Julien Praline
    ALS Centre, Service de Neurologie et de Neurophysiologie Clinique, CHU Bretonneau, 2 boulevard Tonnelle, Tours Cedex 9, France
    Amyotroph Lateral Scler 13:155-7. 2012
  3. doi request reprint The P413L chromogranin B variation in French patients with sporadic amyotrophic lateral sclerosis
    Helene Blasco
    UMR Inserm U930, Universite Francois Rabelais de Tours, France
    Amyotroph Lateral Scler 12:210-4. 2011
  4. pmc Homozygous SMN2 deletion is a protective factor in the Swedish ALS population
    Philippe Corcia
    Centre SLA, CHRU de Tours, Tours, France
    Eur J Hum Genet 20:588-91. 2012
  5. doi request reprint Association between divalent metal transport 1 encoding gene (SLC11A2) and disease duration in amyotrophic lateral sclerosis
    Helene Blasco
    UMR INSERM U930 CNRS 2448, Universite Francois Rabelais de Tours, Tours, France
    J Neurol Sci 303:124-7. 2011
  6. doi request reprint Mutations of the ANG gene in French patients with sporadic amyotrophic lateral sclerosis
    Agathe Paubel
    INSERM U930, Université François Rabelais Tours, CHRU de Tours, Faculte de Medecine, 10 boulevard Tonnelle, BP3223, 37032 Tours Cedex, France
    Arch Neurol 65:1333-6. 2008
  7. doi request reprint Malnutrition at the time of diagnosis is associated with a shorter disease duration in ALS
    Nadege Limousin
    Centre SLA, Service de Neurologie et de Neurophysiologie Clinique, CHRU, Tours, France
    J Neurol Sci 297:36-9. 2010
  8. ncbi request reprint CADASIL and ALS: a link?
    Julien Praline
    ALS Centre, Service de Neurologie et de Neurophysiologie Clinique, CHRU, Tours, France
    Amyotroph Lateral Scler 11:399-401. 2010
  9. doi request reprint Primary lateral sclerosis may occur within familial amyotrophic lateral sclerosis pedigrees
    Julien Praline
    ALS Centre, Tours, France
    Amyotroph Lateral Scler 11:154-6. 2010
  10. doi request reprint Protein SUMOylation, an emerging pathway in amyotrophic lateral sclerosis
    Audrey Dangoumau
    UMR Inserm U930, Universite Francois Rabelais, Tours, France
    Int J Neurosci 123:366-74. 2013

Collaborators

Detail Information

Publications18

  1. doi request reprint Study of the HFE gene common polymorphisms in French patients with sporadic amyotrophic lateral sclerosis
    Julien Praline
    UMR Inserm U930, Universite Francois Rabelais, Tours, France Centre SLA, Service de Neurologie et Neurophysiologie Clinique, CHRU de Tours, France
    J Neurol Sci 317:58-61. 2012
    ..This conclusion does not exclude a weak effect of the HFE gene polymorphisms in certain ALS populations, or an effect of other rare HFE gene variants...
  2. doi request reprint Co-occurrence of progressive anarthria with an S393L TARDBP mutation and ALS within a family
    Julien Praline
    ALS Centre, Service de Neurologie et de Neurophysiologie Clinique, CHU Bretonneau, 2 boulevard Tonnelle, Tours Cedex 9, France
    Amyotroph Lateral Scler 13:155-7. 2012
    ..It has been previously reported in sporadic and familial amyotrophic lateral sclerosis. This case strengthens the hypothesis of a continuum between motor neuron disease and frontotemporal lobar degeneration among TDP-43 proteinopathies...
  3. doi request reprint The P413L chromogranin B variation in French patients with sporadic amyotrophic lateral sclerosis
    Helene Blasco
    UMR Inserm U930, Universite Francois Rabelais de Tours, France
    Amyotroph Lateral Scler 12:210-4. 2011
    ..4 vs. 62.0 years of age, respectively). Thus, our findings do not support the 413L variant of rs742710 as a risk factor for sporadic ALS in the French population...
  4. pmc Homozygous SMN2 deletion is a protective factor in the Swedish ALS population
    Philippe Corcia
    Centre SLA, CHRU de Tours, Tours, France
    Eur J Hum Genet 20:588-91. 2012
    ..We also suggest that SMN2 gene copy number might have different effects on ALS progression in disparate human populations...
  5. doi request reprint Association between divalent metal transport 1 encoding gene (SLC11A2) and disease duration in amyotrophic lateral sclerosis
    Helene Blasco
    UMR INSERM U930 CNRS 2448, Universite Francois Rabelais de Tours, Tours, France
    J Neurol Sci 303:124-7. 2011
    ..SLC11A2 gene encodes the divalent metal transport 1 (DMT1) mediating iron transport in cerebral endosomal compartments. The objective of the study was to analyze DMT1 as a possible risk or modulating factor in sporadic ALS (SALS)...
  6. doi request reprint Mutations of the ANG gene in French patients with sporadic amyotrophic lateral sclerosis
    Agathe Paubel
    INSERM U930, Université François Rabelais Tours, CHRU de Tours, Faculte de Medecine, 10 boulevard Tonnelle, BP3223, 37032 Tours Cedex, France
    Arch Neurol 65:1333-6. 2008
    ..However, the cellular and molecular mechanisms that link ANG, a multidomain protein, to ALS are still unknown...
  7. doi request reprint Malnutrition at the time of diagnosis is associated with a shorter disease duration in ALS
    Nadege Limousin
    Centre SLA, Service de Neurologie et de Neurophysiologie Clinique, CHRU, Tours, France
    J Neurol Sci 297:36-9. 2010
    ..The aim of our study was to determine whether clinical nutritional parameters that are used in daily practice are associated with prognosis and whether they can help guide therapeutic decisions...
  8. ncbi request reprint CADASIL and ALS: a link?
    Julien Praline
    ALS Centre, Service de Neurologie et de Neurophysiologie Clinique, CHRU, Tours, France
    Amyotroph Lateral Scler 11:399-401. 2010
    ..The possible pathogenic role for a mutation in the Notch3 gene is discussed considering recent data on hypoxia in the pathophysiology of ALS...
  9. doi request reprint Primary lateral sclerosis may occur within familial amyotrophic lateral sclerosis pedigrees
    Julien Praline
    ALS Centre, Tours, France
    Amyotroph Lateral Scler 11:154-6. 2010
    ..These observations strengthen the hypothesis that PLS may represent an ALS phenotype with a long evolution and strongly suggest the involvement of common genetic factors that can lead to upper and lower motor neuron death...
  10. doi request reprint Protein SUMOylation, an emerging pathway in amyotrophic lateral sclerosis
    Audrey Dangoumau
    UMR Inserm U930, Universite Francois Rabelais, Tours, France
    Int J Neurosci 123:366-74. 2013
    ..In this review, we summarize the functioning of the SUMO pathway in normal conditions and in response to stresses, its action on ALS-related proteins and discuss the need for further research on this pathway in ALS...
  11. doi request reprint The high frequency of restless legs syndrome in patients with amyotrophic lateral sclerosis
    Nadege Limousin
    Centre SLA, Service de Neurologie et de Neurophysiologie Clinique, CHRU, Tours, France
    Amyotroph Lateral Scler 12:303-6. 2011
    ..023). In conclusion, RLS occurs frequently in ALS, and those affected should be identified and appropriately treated...
  12. ncbi request reprint Pure bulbar motor neuron involvement linked to an abnormal CAG repeat expansion in the androgen receptor gene
    Julien Praline
    ALSCentre, CHRUde Tours, Tours, France
    Amyotroph Lateral Scler 9:40-2. 2008
    ..This atypical phenotype led us to discuss the role of some genetic or environmental factors in SBMA...
  13. doi request reprint Occurrence of eye movement disorders in motor neuron disease
    Emilie Beaufils
    MCentre SLA, Service de Neurologie et de Neurophysiologie Clinique CHRU de Tours, Tours, France
    Amyotroph Lateral Scler 13:84-6. 2012
    ..Motor neuron disease with eye movement disorders must not be considered as a distinct clinical entity and must not exclude a diagnosis of ALS...
  14. pmc 1H-NMR-based metabolomic profiling of CSF in early amyotrophic lateral sclerosis
    Helene Blasco
    INSERM U930, CNRS 2448, Tours, France
    PLoS ONE 5:e13223. 2010
    ....
  15. doi request reprint The importance of the SMN genes in the genetics of sporadic ALS
    Philippe Corcia
    ALS Centre, CHU Tours, INSERM, Universite Francois Rabelais, 2 boulevard Tonnelle, Tours Cedex 1, France
    Amyotroph Lateral Scler 10:436-40. 2009
    ..The existence of abnormal SMN1 copy numbers in ALS provides additional evidence that gene copy number variants may contribute to neurodegeneration and might open new approaches to treatment...
  16. pmc Molecular imaging of microglial activation in amyotrophic lateral sclerosis
    Philippe Corcia
    ALS Center, Department of Neurology, CHRU Bretonneau, Tours, France
    PLoS ONE 7:e52941. 2012
    ..This finding might improve our understanding of the pathophysiology of ALS and might be a surrogate marker of efficacy of treatment on microglial activation...
  17. ncbi request reprint Somatosensory evoked potentials in chronic inflammatory demyelinating polyradiculoneuropathy
    Hayet Salhi
    Department of Neurology Neurophysiology, Hospital of Tours, France and INSERM UMR930, Tours, France
    J Clin Neurophysiol 31:241-5. 2014
    ..Somatosensory evoked potentials (SEPs) offer complementary results to those of nerve conduction studies and contribute to the electrodiagnostic criteria of chronic inflammatory demyelinating polyradiculoneuropathy...
  18. ncbi request reprint ALS and mercury intoxication: a relationship?
    Julien Praline
    Department of Neurology and Neurophysiology, CHRU, Tours, France
    Clin Neurol Neurosurg 109:880-3. 2007
    ..Although no autopsy was performed, we discuss the role of mercury intoxication in the occurrence of ALS in our case, considering the results of experimental studies on the toxicity of mercury for motor neuron...