J M Poul

Summary

Country: France

Publications

  1. ncbi Lack of genotoxicity of potassium iodate in the alkaline comet assay and in the cytokinesis-block micronucleus test. Comparison to potassium bromate
    J M Poul
    AFSSA, Laboratoire d Etudes et de Recherches sur les Médicaments Vétérinaires et les Désinfectants, Unité de Toxicologie Alimentaire, BP 90203, 35302 Cedex Fougères, France
    Food Chem Toxicol 42:203-9. 2004
  2. doi Lack of genotoxic effect of food dyes amaranth, sunset yellow and tartrazine and their metabolites in the gut micronucleus assay in mice
    Martine Poul
    Agence Francaise de Securite Sanitaire des Aliments, Unité de Toxicologie Génétique des Contaminants Alimentaires, La Haute Marche, Javene, F 35133 Fougères, France
    Food Chem Toxicol 47:443-8. 2009
  3. ncbi Evaluation of the genotoxic potential of 3-monochloropropane-1,2-diol (3-MCPD) and its metabolites, glycidol and beta-chlorolactic acid, using the single cell gel/comet assay
    R El Ramy
    Agence Francaise de Securite Sanitaire des Aliments, Unité de Toxicologie Génétique des Contaminants Alimentaires, la Haute Marche 35133 Javené, Fougeres, France
    Food Chem Toxicol 45:41-8. 2007
  4. ncbi Effects of griseofulvin in medium-term liver carcinogenesis assay and peripheral blood micronucleus test in rat
    K Labay
    Agence Francaise de Securite Sanitaire des Aliments, Laboratoire d Etudes et de Recherches sur les Médicaments Vétérinaires et les Désinfectants, Fougères Cedex, France
    Teratog Carcinog Mutagen 21:441-51. 2001
  5. ncbi Oral toxicity in weanling and adult rats and in vitro genotoxicity of the veterinary anthelmintic rafoxanide
    J M Poul
    Centre National d Etudes Vétérinaires et Alimentaires Laboratoire des Médicaments Vétérinaires, Javene, Fougeres, France
    J Appl Toxicol 13:117-22. 1993
  6. ncbi Evaluation of residual and therapeutic doses of tetracycline in the human-flora-associated (HFA) mice model
    A Perrin-Guyomard
    Laboratoire d Etudes et de Recherches sur les Médicaments Vétérinaires et les Désinfectants, Agence Francaise de Securite Sanitaire des Aliments, BP 90203, 35302 Fougeres Cedex, France
    Regul Toxicol Pharmacol 34:125-36. 2001

Collaborators

Detail Information

Publications6

  1. ncbi Lack of genotoxicity of potassium iodate in the alkaline comet assay and in the cytokinesis-block micronucleus test. Comparison to potassium bromate
    J M Poul
    AFSSA, Laboratoire d Etudes et de Recherches sur les Médicaments Vétérinaires et les Désinfectants, Unité de Toxicologie Alimentaire, BP 90203, 35302 Cedex Fougères, France
    Food Chem Toxicol 42:203-9. 2004
    ..The repair of bromate-induced DNA damage was incomplete 24 h after the end of treatment. These results seem to indicate that potassium bromate would induce DNA damage by several mechanisms besides oxidative stress...
  2. doi Lack of genotoxic effect of food dyes amaranth, sunset yellow and tartrazine and their metabolites in the gut micronucleus assay in mice
    Martine Poul
    Agence Francaise de Securite Sanitaire des Aliments, Unité de Toxicologie Génétique des Contaminants Alimentaires, La Haute Marche, Javene, F 35133 Fougères, France
    Food Chem Toxicol 47:443-8. 2009
    ..2002. The comet assay with 8 mouse organs: results with 39 currently used food additives. Mutat. Res. 519, 103-119] are unable to be fixed in stable genotoxic lesions and might be partly explained by local cytotoxicity of the dyes...
  3. ncbi Evaluation of the genotoxic potential of 3-monochloropropane-1,2-diol (3-MCPD) and its metabolites, glycidol and beta-chlorolactic acid, using the single cell gel/comet assay
    R El Ramy
    Agence Francaise de Securite Sanitaire des Aliments, Unité de Toxicologie Génétique des Contaminants Alimentaires, la Haute Marche 35133 Javené, Fougeres, France
    Food Chem Toxicol 45:41-8. 2007
    ..Glycidol, the epoxide metabolite, induced DNA damages in CHO cells. beta-Chlorolactic acid, the main metabolite of 3-MCPD in rats, was shown to be devoid of DNA-damaging effects in vitro in mammalian cells...
  4. ncbi Effects of griseofulvin in medium-term liver carcinogenesis assay and peripheral blood micronucleus test in rat
    K Labay
    Agence Francaise de Securite Sanitaire des Aliments, Laboratoire d Etudes et de Recherches sur les Médicaments Vétérinaires et les Désinfectants, Fougères Cedex, France
    Teratog Carcinog Mutagen 21:441-51. 2001
    ..Griseofulvin was found to be negative in the rat peripheral blood micronucleus test when given at a daily oral dose of 2,000 mg/kg body weight for at least 3 weeks...
  5. ncbi Oral toxicity in weanling and adult rats and in vitro genotoxicity of the veterinary anthelmintic rafoxanide
    J M Poul
    Centre National d Etudes Vétérinaires et Alimentaires Laboratoire des Médicaments Vétérinaires, Javene, Fougeres, France
    J Appl Toxicol 13:117-22. 1993
    ..In adult rats treated orally for 3 months with 1, 5 or 25 mg kg-1 Rafoxanide, biochemical and haematological tests did not reveal dose-related effects. Rafoxanide had no mutagenic activity in the Ames and CHO/HGPRT tests...
  6. ncbi Evaluation of residual and therapeutic doses of tetracycline in the human-flora-associated (HFA) mice model
    A Perrin-Guyomard
    Laboratoire d Etudes et de Recherches sur les Médicaments Vétérinaires et les Désinfectants, Agence Francaise de Securite Sanitaire des Aliments, BP 90203, 35302 Fougeres Cedex, France
    Regul Toxicol Pharmacol 34:125-36. 2001
    ..Within the constraints of the experimental design employed here, the HFA mice model proved to be acceptable for studying dose-related effects of tetracycline on human intestinal microflora...