L Poirel

Summary

Country: France

Publications

  1. pmc Molecular and biochemical characterization of VEB-1, a novel class A extended-spectrum beta-lactamase encoded by an Escherichia coli integron gene
    L Poirel
    Service de Bacteriologie Virologie, Hopital de Bicetre, Faculte de Medecine Paris Sud, France
    Antimicrob Agents Chemother 43:573-81. 1999
  2. ncbi request reprint Carbapenem resistance in Acinetobacter baumannii: mechanisms and epidemiology
    L Poirel
    Service de Bacteriologie Virologie, Hopital de Bicetre, South Paris Medical School, University Paris XI, Le Kremlin Bicetre, France
    Clin Microbiol Infect 12:826-36. 2006
  3. ncbi request reprint Acquired carbapenem-hydrolyzing beta-lactamases and their genetic support
    L Poirel
    Service de Bacteriologie Virologie, Hĵpital de Bicêtre, Le Kremlin Bicetre, France
    Curr Pharm Biotechnol 3:117-27. 2002
  4. pmc Characterization of In53, a class 1 plasmid- and composite transposon-located integron of Escherichia coli which carries an unusual array of gene cassettes
    T Naas
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculte de Medecine Paris Sud, 94275 Le Kremlin Bicetre, France
    J Bacteriol 183:235-49. 2001
  5. pmc Characterization of VIM-2, a carbapenem-hydrolyzing metallo-beta-lactamase and its plasmid- and integron-borne gene from a Pseudomonas aeruginosa clinical isolate in France
    L Poirel
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculte de Medecine Paris Sud, 94275 Le Kremlin Bicetre, France
    Antimicrob Agents Chemother 44:891-7. 2000
  6. pmc Characterization of Class 1 integrons from Pseudomonas aeruginosa that contain the bla(VIM-2) carbapenem-hydrolyzing beta-lactamase gene and of two novel aminoglycoside resistance gene cassettes
    L Poirel
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculte de Medecine Paris Sud, 94275 Le Kremlin Bicetre, France
    Antimicrob Agents Chemother 45:546-52. 2001
  7. ncbi request reprint Plasmid-mediated extended-spectrum beta-lactamase (CTX-M-3 like) from India and gene association with insertion sequence ISEcp1
    A Karim
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculté de Médicine Paris Sud, France
    FEMS Microbiol Lett 201:237-41. 2001
  8. doi request reprint Carbapenem-resistant and OXA-23-producing Acinetobacter baumannii isolates in the United Arab Emirates
    P Mugnier
    Service de Bacteriologie Virologie, INSERM U914, Emerging Resistance to Antibiotics, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculté de Médecine et Université Paris Sud, Bicetre, France
    Clin Microbiol Infect 14:879-82. 2008
  9. ncbi request reprint Molecular characterization of In50, a class 1 integron encoding the gene for the extended-spectrum beta-lactamase VEB-1 in Pseudomonas aeruginosa
    T Naas
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculte de Medecine Paris Sud, France
    FEMS Microbiol Lett 176:411-9. 1999
  10. doi request reprint Identification of the naturally occurring genes encoding carbapenem-hydrolysing oxacillinases from Acinetobacter haemolyticus, Acinetobacter johnsonii, and Acinetobacter calcoaceticus
    S Figueiredo
    Service de Bacteriologie Virologie, INSERM U914 Emerging Resistance to Antibiotics, Département Anesthésie Réanimation, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculté de Médecine et Université Paris Sud, K Bicêtre, France
    Clin Microbiol Infect 18:907-13. 2012

Collaborators

Detail Information

Publications53

  1. pmc Molecular and biochemical characterization of VEB-1, a novel class A extended-spectrum beta-lactamase encoded by an Escherichia coli integron gene
    L Poirel
    Service de Bacteriologie Virologie, Hopital de Bicetre, Faculte de Medecine Paris Sud, France
    Antimicrob Agents Chemother 43:573-81. 1999
    ..Furthermore, blaVEB-1 is encoded on a large (> 100-kb) transferable plasmid found in a Klebsiella pneumoniae MG-2 isolated at the same time from the same patient, indicating a horizontal gene transfer...
  2. ncbi request reprint Carbapenem resistance in Acinetobacter baumannii: mechanisms and epidemiology
    L Poirel
    Service de Bacteriologie Virologie, Hopital de Bicetre, South Paris Medical School, University Paris XI, Le Kremlin Bicetre, France
    Clin Microbiol Infect 12:826-36. 2006
    ..baumannii may also result from porin or penicillin-binding protein modifications. Several porins, including the 33-kDa CarO protein, that constitute a pore channel for influx of carbapenems, might be involved in carbapenem resistance...
  3. ncbi request reprint Acquired carbapenem-hydrolyzing beta-lactamases and their genetic support
    L Poirel
    Service de Bacteriologie Virologie, Hĵpital de Bicêtre, Le Kremlin Bicetre, France
    Curr Pharm Biotechnol 3:117-27. 2002
    ..This review underlines the worldwide spread of carbapenem-hydrolyzing beta-lactamases as representing an important threat for efficacy of antibiotics in the near future...
  4. pmc Characterization of In53, a class 1 plasmid- and composite transposon-located integron of Escherichia coli which carries an unusual array of gene cassettes
    T Naas
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculte de Medecine Paris Sud, 94275 Le Kremlin Bicetre, France
    J Bacteriol 183:235-49. 2001
    ..Target site duplication at both ends of the transposon indicated that the integron likely was inserted into the plasmid through a transpositional process. This is the first description of an integron located on a composite transposon...
  5. pmc Characterization of VIM-2, a carbapenem-hydrolyzing metallo-beta-lactamase and its plasmid- and integron-borne gene from a Pseudomonas aeruginosa clinical isolate in France
    L Poirel
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculte de Medecine Paris Sud, 94275 Le Kremlin Bicetre, France
    Antimicrob Agents Chemother 44:891-7. 2000
    ..VIM-2 is the second carbapenem-hydrolyzing metalloenzyme characterized from a P. aeruginosa isolate outside Japan...
  6. pmc Characterization of Class 1 integrons from Pseudomonas aeruginosa that contain the bla(VIM-2) carbapenem-hydrolyzing beta-lactamase gene and of two novel aminoglycoside resistance gene cassettes
    L Poirel
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculte de Medecine Paris Sud, 94275 Le Kremlin Bicetre, France
    Antimicrob Agents Chemother 45:546-52. 2001
    ..They conferred resistance to amikacin, isepamicin, kanamycin, and tobramycin but not to gentamicin, netilmicin, and sisomicin...
  7. ncbi request reprint Plasmid-mediated extended-spectrum beta-lactamase (CTX-M-3 like) from India and gene association with insertion sequence ISEcp1
    A Karim
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculté de Médicine Paris Sud, France
    FEMS Microbiol Lett 201:237-41. 2001
    ..The location of ISEcp1 upstream of plasmid-mediated CTX-M-type beta-lactamase genes may contribute to their spread or/and their expression...
  8. doi request reprint Carbapenem-resistant and OXA-23-producing Acinetobacter baumannii isolates in the United Arab Emirates
    P Mugnier
    Service de Bacteriologie Virologie, INSERM U914, Emerging Resistance to Antibiotics, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculté de Médecine et Université Paris Sud, Bicetre, France
    Clin Microbiol Infect 14:879-82. 2008
    ..The single non-clonally related isolate harboured the bla(OXA-23) gene on a 70-kb transferable plasmid. This study reports on the dissemination of OXA-23-producing A. baumannii isolates in the Middle East...
  9. ncbi request reprint Molecular characterization of In50, a class 1 integron encoding the gene for the extended-spectrum beta-lactamase VEB-1 in Pseudomonas aeruginosa
    T Naas
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculte de Medecine Paris Sud, France
    FEMS Microbiol Lett 176:411-9. 1999
    ..The finding of blaVEB-1 in these strains and on different integrons underlines the interspecies spread of this integron-located extended-spectrum beta-lactamase gene...
  10. doi request reprint Identification of the naturally occurring genes encoding carbapenem-hydrolysing oxacillinases from Acinetobacter haemolyticus, Acinetobacter johnsonii, and Acinetobacter calcoaceticus
    S Figueiredo
    Service de Bacteriologie Virologie, INSERM U914 Emerging Resistance to Antibiotics, Département Anesthésie Réanimation, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculté de Médecine et Université Paris Sud, K Bicêtre, France
    Clin Microbiol Infect 18:907-13. 2012
    ..lwoffii, these genes were not expressed (or expressed at a non-significant level) in their host. Detection of these β-lactamase genes might be used as a useful tool for accurate identification of these Acinetobacter species...
  11. ncbi request reprint Cephalosporinase over-expression resulting from insertion of ISAba1 in Acinetobacter baumannii
    C Heritier
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculte de Medecine Paris Sud, Universite Paris XI, Le Kremlin Bicetre, France
    Clin Microbiol Infect 12:123-30. 2006
    ..Sequence analysis revealed that AmpC sequences of A. baumannii isolates were almost identical and that ISAba1 elements had a high percentage of identity...
  12. pmc Biochemical-genetic characterization and distribution of OXA-22, a chromosomal and inducible class D beta-lactamase from Ralstonia (Pseudomonas) pickettii
    P Nordmann
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculte de Medecine Paris Sud, 94275 Le Kremlin Bicetre, France
    Antimicrob Agents Chemother 44:2201-4. 2000
    ..OXA-22-like genes were identified as single chromosomal copies in five other R. pickettii clinical isolates. The expression of OXA-22-like beta-lactamases was inducible in R. pickettii...
  13. doi request reprint Prevalence of plasmid-mediated quinolone resistance determinants in Enterobacteriaceae from Tunisia
    S Dahmen
    Service de Bacteriologie Virologie, INSERM U914 Emerging Resistance to Antibiotics, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculté de Médecine et Université Paris Sud, France
    Clin Microbiol Infect 16:1019-23. 2010
    ..The present study highlights the wide spread of Qnr-like determinants in Tunisia, with an association with the ESBL CTX-M-15 in human clinical isolates...
  14. pmc CTX-M-type extended-spectrum beta-lactamase that hydrolyzes ceftazidime through a single amino acid substitution in the omega loop
    L Poirel
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculte de Medecine Paris Sud, 94275 Le Kremlin Bicetre cedex, France
    Antimicrob Agents Chemother 45:3355-61. 2001
    ..The bla(CTX-M-18) and bla(CTX-M-19) genes were located on transferable plasmids that varied in size (ca. 60 and 50 kb, respectively) but that showed similar restriction patterns...
  15. ncbi request reprint Pyrosequencing for rapid identification of carbapenem-hydrolysing OXA-type beta-lactamases in Acinetobacter baumannii
    T Naas
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculte de Medecine Paris Sud, Universite Paris XI, K Bicêtre, France
    Clin Microbiol Infect 12:1236-40. 2006
    ..baumannii and Acinetobacter junii. Pyrosequencing may provide a rapid tool for identification of OXA variants, thus avoiding delays inherent in classical sequencing methods...
  16. pmc Biochemical-genetic characterization of the chromosomally encoded extended-spectrum class A beta-lactamase from Rahnella aquatilis
    S Bellais
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculte de Medecine Paris Sud, 78 Rue de Général Leclerc, 94275 Le Kremlin Bicetre cedex, France
    Antimicrob Agents Chemother 45:2965-8. 2001
    ..The hydrolysis spectrum of the clavulanic acid-inhibited RAHN-1 was expanded to cephalosporins such as cefuroxime, cefotaxime, and ceftriaxone, but not to ceftazidime. Its expression was not inducible...
  17. ncbi request reprint Genetic support of extended-spectrum beta-lactamases
    L Poirel
    Service de Bacteriologie Virologie, Hopital de Bicetre, South Paris Medical School, University Paris XI, Le Kremlin Bicetre, France
    Clin Microbiol Infect 14:75-81. 2008
    ..This diversity of genetic vehicles at the origin of these mobilisation/acquisition processes enhances the spread of ESBLs...
  18. pmc Biochemical sequence analyses of GES-1, a novel class A extended-spectrum beta-lactamase, and the class 1 integron In52 from Klebsiella pneumoniae
    L Poirel
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, France
    Antimicrob Agents Chemother 44:622-32. 2000
    ..This work identified the second class A ESBL gene of a non-TEM, non-SHV series which was located in the plasmid and integron, thus providing it additional means for its spread and its expression...
  19. ncbi request reprint Minor extended-spectrum beta-lactamases
    T Naas
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculte de Medecine Paris Sud, Universite Paris XI, 94275 K Bicêtre, France
    Clin Microbiol Infect 14:42-52. 2008
    ..In addition, mutations can extend the spectrum of some OXA-type beta-lactamases to include expanded-spectrum cephalosporins, and several of these enzymes are considered to be ESBLs...
  20. pmc Biochemical-genetic analysis and distribution of FAR-1, a class A beta-lactamase from Nocardia farcinica
    F Laurent
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculte de Medecine Paris Sud, 94275 Le Kremlin Bicetre cedex, France
    Antimicrob Agents Chemother 43:1644-50. 1999
    ..A blaFAR-1-like gene was found in all studied N. farcinica strains, underlining the constitutive origin of this gene...
  21. ncbi request reprint Long-term evolution of a nosocomial outbreak of Pseudomonas aeruginosa producing VIM-2 metallo-enzyme
    S Corvec
    Service de Bacteriologie Virologie, INSERM U914 Emerging Resistance to Antibiotics Hôpital de Bicêtre, Assistance Publique Hopitaux de Paris, Faculte de Medecine Paris Sud, K Bicêtre, France
    J Hosp Infect 68:73-82. 2008
    ....
  22. doi request reprint Dissemination of New Delhi metallo-β-lactamase-1-producing Acinetobacter baumannii in Europe
    R A Bonnin
    Service de Bacteriologie Virologie, INSERM U914 Emerging Resistance to Antibiotics, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculté de Médecine et Université Paris Sud, K Bicêtre, France
    Clin Microbiol Infect 18:E362-5. 2012
    ..One isolate co-expressed another unrelated carbapenemase OXA-23. This report constitutes the first epidemiological study of NDM-1-producing A. baumannii from four countries...
  23. doi request reprint European dissemination of a single OXA-48-producing Klebsiella pneumoniae clone
    A Potron
    Service de Bacteriologie Virologie, INSERM U914 Emerging Resistance to Antibiotics, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculté de Médecine et Université Paris Sud, K Bicêtre, France
    Clin Microbiol Infect 17:E24-6. 2011
    ..This study sheds light on the European dissemination of a single OXA-48 K. pneumoniae clone...
  24. ncbi request reprint In-vitro mutagenesis of qnrA and qnrS genes and quinolone resistance in Escherichia coli
    V Cattoir
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculte de Medecine Paris Sud, Universite Paris XI, France
    Clin Microbiol Infect 13:940-3. 2007
    ....
  25. ncbi request reprint Nosocomial spread of OXA-58-positive carbapenem-resistant Acinetobacter baumannii isolates in a paediatric hospital in Greece
    L Poirel
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculte de Medecine Paris Sud, Le Kremlin Bicetre, France
    Clin Microbiol Infect 12:1138-41. 2006
    ..This study emphasises the importance of the bla(OXA-58) carbapenemase gene in conferring carbapenem resistance among A. baumannii isolates in Greece...
  26. doi request reprint Genetic diversity of carbapenem-hydrolysing β-lactamases in Acinetobacter baumannii from Romanian hospitals
    R A Bonnin
    Service de Bacteriologie Virologie, INSERM U914 Emerging Resistance to Antibiotics, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculté de Médecine et Université Paris Sud, K Bicêtre, France
    Clin Microbiol Infect 17:1524-8. 2011
    ..Two isolates co-expressed OXA-23 together with the extended-spectrum β-lactamase PER-1. This study constitutes the first report of OXA-58 and OXA-23-producing A. baumannii isolates in Romania...
  27. doi request reprint NDM-1, OXA-48 and OXA-181 carbapenemase-producing Enterobacteriaceae in Sultanate of Oman
    L Dortet
    Service de Bacteriologie Virologie, INSERM U914 Emerging Resistance to Antibiotics, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculte de Medecine Paris Sud, 78 rue du General Leclerc, Le Kremlin Bicetre Cedex, France
    Clin Microbiol Infect 18:E144-8. 2012
    ..This work highlights the dissemination of NDM-1 and OXA-48-type producers in the Middle East...
  28. doi request reprint Carbapenem-hydrolyzing class D β-lactamase OXA-48 in Klebsiella pneumoniae isolates from Tunisia
    H Lahlaoui
    Service de Bacteriologie Virologie, INSERM U914, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculté de Médecine et Université Paris Sud, K Bicêtre, France
    Eur J Clin Microbiol Infect Dis 31:937-9. 2012
    ..Molecular investigations showed that both isolates co-produced the narrow-spectrum β-lactamases TEM-1 and SHV-1, together with the extended-spectrum β-lactamase CTX--15...
  29. doi request reprint Identification and screening of carbapenemase-producing Enterobacteriaceae
    P Nordmann
    Service de Bacteriologie Virologie, INSERM U914 Emerging Resistance to Antibiotics, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculté de Médecine et Université Paris Sud, K Bicêtre, France
    Clin Microbiol Infect 18:432-8. 2012
    ..Phenotypic and molecular-based techniques are able to identify these carbapenemase producers, although with variable efficiencies. The detection of carriers still relies mostly on the use of screening culture media...
  30. ncbi request reprint Molecular characterisation of In51, a class 1 integron containing a novel aminoglycoside adenylyltransferase gene cassette, aadA6, in Pseudomonas aeruginosa
    T Naas
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Le Kremlin Bicetre, France
    Biochim Biophys Acta 1489:445-51. 1999
    ..AADA6 enzyme has only 75% amino acid identity with AADA1 and is able to confer high level resistance to streptomycin and spectinomycin in Escherichia coli...
  31. ncbi request reprint Plasmid-mediated quinolone resistance determinant qnrS in Enterobacter cloacae
    L Poirel
    Service de Bacteriologie Virologie, Hopital de Bicetre, Faculte de Medecine Paris Sud, Universite Paris XI, Le Kremlin Bicetre, France
    Clin Microbiol Infect 12:1021-3. 2006
    ..Cloning and sequencing identified a qnrS gene bracketed by open reading frames identical to those surrounding the qnrS gene of a Shigella flexneri isolate from Japan, thereby suggesting a common mechanism of acquisition...
  32. ncbi request reprint Emerging carbapenemases in Gram-negative aerobes
    P Nordmann
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hôpitaux de Paris and Faculté de Médecine Paris Sud, Universite Paris XI, Paris, France
    Clin Microbiol Infect 8:321-31. 2002
    ..Because most of these carbapenemases confer only reduced susceptibility to carbapenems in Enterobacteriaceae, they may remain underestimated as a consequence of the lack of their detection...
  33. doi request reprint Metallo-beta-lactamase-producing Pseudomonas aeruginosa isolated from a large tertiary centre in Kenya
    J D D Pitout
    Division of Microbiology, Calgary Laboratory Services, Department of Pathology and Laboratory Medicine, and Microbiology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada
    Clin Microbiol Infect 14:755-9. 2008
    ..This study is the first report of VIM-2-producing P. aeruginosa from the African continent...
  34. ncbi request reprint Is plasmid-mediated quinolone resistance a clinically significant problem?
    L Poirel
    Clin Microbiol Infect 14:295-7. 2008
    ....
  35. doi request reprint First identification of VIM-4 metallo-beta-lactamase in Acinetobacter spp
    S Figueiredo
    Clin Microbiol Infect 14:289-90. 2008
  36. pmc GES-2, a class A beta-lactamase from Pseudomonas aeruginosa with increased hydrolysis of imipenem
    L Poirel
    , , , , , France
    Antimicrob Agents Chemother 45:2598-603. 2001
    ..This amino acid change may explain the extension of the substrate profile of the plasmid-encoded beta-lactamase GES-2...
  37. pmc Molecular epidemiology of the integron-located VEB-1 extended-spectrum beta-lactamase in nosocomial enterobacterial isolates in Bangkok, Thailand
    D Girlich
    , , , , , France
    J Clin Microbiol 39:175-82. 2001
    ..Plasmid- and integron-mediated resistance to rifampin was also found in enterobacterial isolates...
  38. ncbi request reprint Incidence of class A extended-spectrum beta-lactamases in Champagne-Ardenne (France): a 1 year prospective study
    L Brasme
    Laboratoire de Bactériologie Virologie Hygiène CHU de Reims, UFR Médecine Université Reims Champagne Ardenne, 51092 Reims, France
    J Antimicrob Chemother 60:956-64. 2007
    ..To assess the frequency and diversity of extended spectrum beta-lactamases (ESBLs) in the Champagne-Ardenne region France, and to identify genetic elements associated with the bla(CTX-M) genes...
  39. pmc Characterization of a chromosomally encoded extended-spectrum class A beta-lactamase from Kluyvera cryocrescens
    J W Decousser
    , , , , , France
    Antimicrob Agents Chemother 45:3595-8. 2001
    ..The substrate profile of KLUC-1 corresponded to that of CTX-M-type enzymes...
  40. ncbi request reprint Emergence of carbapenem-hydrolysing metallo-beta-lactamase VIM-1 in Pseudomonas aeruginosa isolates in France
    S Corvec
    Clin Microbiol Infect 12:941-2. 2006
  41. ncbi request reprint Bactericidal activity of fluoroquinolones against plasmid-mediated QnrA-producing Escherichia coli
    H Mammeri
    Clin Microbiol Infect 11:1048-9. 2005
  42. ncbi request reprint OXA-35 is an OXA-10-related beta-lactamase from Pseudomonas aeruginosa
    D Aubert
    , , , , , Paris, France
    J Antimicrob Chemother 48:717-21. 2001
    ..OXA-35 differs from derivatives OXA-19 and OXA-28 by one amino acid substitution and may be a progenitor of these OXA-13-like extended-spectrum beta-lactamases...
  43. ncbi request reprint Carbapenem-hydrolysing metallo-beta-lactamases from Klebsiella pneumoniae and Escherichia coli isolated in Australia
    L Poirel
    Pathology 36:366-7. 2004
  44. ncbi request reprint Isolation of an extended spectrum beta-lactamase producing Pseudomonas aeruginosa from a patient in a Sydney hospital
    S M Bell
    Pathology 39:189-90. 2007
  45. ncbi request reprint In vivo selection of oxacillinase-mediated ceftazidime resistance in Pseudomonas aeruginosa
    S Leotard
    , , , France
    Microb Drug Resist 7:273-5. 2001
    ..This is the first example of in vivo selection of an extended-spectrum oxacillinase from a restricted-spectrum oxacillinase...
  46. ncbi request reprint PER-1- and OXA-10-like beta-lactamases in ceftazidime-resistant Pseudomonas aeruginosa isolates from intensive care unit patients in Istanbul, Turkey
    Z Aktas
    Department of Microbiology and Clinical Microbiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
    Clin Microbiol Infect 11:193-8. 2005
    ..The results indicated that the prevalence of PER-1- and OXA-10-like beta-lactamases remains high among ceftazidime-resistant P. aeruginosa isolates in Turkey...
  47. pmc Molecular characterization of an epidemic clone of panantibiotic-resistant Pseudomonas aeruginosa
    A Deplano
    Department of Microbiology, Hopital Erasme, 808 Route de Lennik, 1070 Brussels, Belgium
    J Clin Microbiol 43:1198-204. 2005
    ..This study illustrates the ability of multiresistant P. aeruginosa to cause an outbreak with significant morbidity and mortality and underscores the need to identify clonal outbreaks, which require targeted infection control measures...
  48. ncbi request reprint Multidrug-resistant Shigella sonnei and Salmonella enterica Serotype typhimurium isolates producing CTX-M beta-lactamases as causes of community-acquired infection in France
    M F Lartigue
    Clin Infect Dis 40:1069-70. 2005
  49. ncbi request reprint First IMP-1-producing Klebsiella pneumoniae isolate in Turkey
    Z Aktas
    Clin Microbiol Infect 12:695-6. 2006
  50. ncbi request reprint Development and clinical validation of a molecular diagnostic assay to detect CTX-M-type beta-lactamases in Enterobacteriaceae
    J D D Pitout
    Division of Microbiology, Calgary Laboratory Services, Calgary, Alberta, Canada
    Clin Microbiol Infect 13:291-7. 2007
    ..The CTX-M-specific PCR assay was reproducible and easy to use. It can be introduced in a clinical or reference laboratory to track and monitor the spread of organisms producing CTX-M enzymes in the community and hospital settings...
  51. pmc Oxacillinase-mediated resistance to cefepime and susceptibility to ceftazidime in Pseudomonas aeruginosa
    D Aubert
    , , , , , France
    Antimicrob Agents Chemother 45:1615-20. 2001
    ..No additional efflux mechanism for cefepime was detected in P. aeruginosa SOF-1. Resistance to cefepime and susceptibility to ceftazidime in P. aeruginosa were conferred by OXA-1 as well...
  52. pmc VEB-1-like extended-spectrum beta-lactamases in Pseudomonas aeruginosa, Kuwait
    L Poirel
    , , France
    Emerg Infect Dis 7:468-70. 2001
    ..This is the first report of extended-spectrum enzymes from nosocomial isolates from the Middle East...
  53. ncbi request reprint First description of CTX-M-15-producing Klebsiella pneumoniae in Turkey
    M F Lartigue
    J Antimicrob Chemother 52:315-6. 2003