Vincent Plagnol

Summary

Country: France

Publications

  1. pmc Relative influences of crossing over and gene conversion on the pattern of linkage disequilibrium in Arabidopsis thaliana
    Vincent Plagnol
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089 2910, USA
    Genetics 172:2441-8. 2006
  2. ncbi request reprint Recombination and linkage disequilibrium in Arabidopsis thaliana
    Sung Kim
    Molecular and Computational Biology, University of Southern California, Los Angeles, California 90089, USA
    Nat Genet 39:1151-5. 2007
  3. pmc Possible ancestral structure in human populations
    Vincent Plagnol
    Department of Molecular and Computational Biology, University of Southern California, Los Angeles, California, USA
    PLoS Genet 2:e105. 2006
  4. ncbi request reprint The evolution of selfing in Arabidopsis thaliana
    Chunlao Tang
    Molecular and Computational Biology, University of Southern California, Los Angeles, CA 90089, USA
    Science 317:1070-2. 2007
  5. pmc Markov chain Monte Carlo without likelihoods
    Paul Marjoram
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA
    Proc Natl Acad Sci U S A 100:15324-8. 2003
  6. pmc The pattern of polymorphism in Arabidopsis thaliana
    Magnus Nordborg
    Molecular and Computational Biology, University of Southern California, Los Angeles, California, USA
    PLoS Biol 3:e196. 2005
  7. ncbi request reprint Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes
    Christopher E Lowe
    Juvenile Diabetes Research Foundation Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke s Hospital, UK
    Nat Genet 39:1074-82. 2007
  8. doi request reprint PTPN22 Trp620 explains the association of chromosome 1p13 with type 1 diabetes and shows a statistical interaction with HLA class II genotypes
    Deborah J Smyth
    Juvenile Diabetes Research Foundation Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
    Diabetes 57:1730-7. 2008
  9. pmc A robust statistical method for case-control association testing with copy number variation
    Chris Barnes
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
    Nat Genet 40:1245-52. 2008

Collaborators

Detail Information

Publications9

  1. pmc Relative influences of crossing over and gene conversion on the pattern of linkage disequilibrium in Arabidopsis thaliana
    Vincent Plagnol
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089 2910, USA
    Genetics 172:2441-8. 2006
    ..The ratio of gene conversion to crossing over is estimated to be around one. We also find evidence for fine-scale variations of the crossing-over rate...
  2. ncbi request reprint Recombination and linkage disequilibrium in Arabidopsis thaliana
    Sung Kim
    Molecular and Computational Biology, University of Southern California, Los Angeles, California 90089, USA
    Nat Genet 39:1151-5. 2007
    ..LD also reflects the action of selection, and it is more extensive between nonsynonymous polymorphisms than between synonymous polymorphisms...
  3. pmc Possible ancestral structure in human populations
    Vincent Plagnol
    Department of Molecular and Computational Biology, University of Southern California, Los Angeles, California, USA
    PLoS Genet 2:e105. 2006
    ..While Neanderthals form an obvious archaic source population candidate in Europe, there is not yet a clear source population candidate in West Africa...
  4. ncbi request reprint The evolution of selfing in Arabidopsis thaliana
    Chunlao Tang
    Molecular and Computational Biology, University of Southern California, Los Angeles, CA 90089, USA
    Science 317:1070-2. 2007
    ..An analysis of the genome-wide pattern of linkage disequilibrium suggests that selfing most likely evolved roughly a million years ago or more...
  5. pmc Markov chain Monte Carlo without likelihoods
    Paul Marjoram
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA
    Proc Natl Acad Sci U S A 100:15324-8. 2003
    ..The approach is illustrated by an example of ancestral inference in population genetics. A number of open problems are highlighted in the discussion...
  6. pmc The pattern of polymorphism in Arabidopsis thaliana
    Magnus Nordborg
    Molecular and Computational Biology, University of Southern California, Los Angeles, California, USA
    PLoS Biol 3:e196. 2005
    ..Despite this, our data support the utility of A. thaliana as a model for evolutionary functional genomics...
  7. ncbi request reprint Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes
    Christopher E Lowe
    Juvenile Diabetes Research Foundation Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke s Hospital, UK
    Nat Genet 39:1074-82. 2007
    ..635). Furthermore, we have associated IL2RA T1D susceptibility genotypes with lower circulating levels of the biomarker, soluble IL-2RA (P = 6.28 x 10(-28)), suggesting that an inherited lower immune responsiveness predisposes to T1D...
  8. doi request reprint PTPN22 Trp620 explains the association of chromosome 1p13 with type 1 diabetes and shows a statistical interaction with HLA class II genotypes
    Deborah J Smyth
    Juvenile Diabetes Research Foundation Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
    Diabetes 57:1730-7. 2008
    ....
  9. pmc A robust statistical method for case-control association testing with copy number variation
    Chris Barnes
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
    Nat Genet 40:1245-52. 2008
    ..We illustrate the power of these methods for testing for association with binary and quantitative traits, and have made this software available as the R package CNVtools...