Stephane Picot

Summary

Country: France

Publications

  1. ncbi request reprint Fluorogenic detection of viable Toxoplasma gondii
    E Borel
    Laboratoire de Parasitologie Mycologie Médicale et Pathologie Exotique, Universite Claude Bernard Lyon I
    Parasite 5:371-3. 1998
  2. ncbi request reprint [Apoptosis and programmed cell death. Host parasite relationship new paradigm]
    S Picot
    L EA 37 32, Praticien, Virulence et résistance des Plasmodium, Faculte de Medecine, Universite Claude Bernard, Lyon, France
    Med Trop (Mars) 66:111-7. 2006
  3. ncbi request reprint [Is Plasmodium vivax still a paradigm for uncomplicated malaria?]
    S Picot
    EA 37 32, virulence et résistance de plasmodium, Faculté de médecine de Lyon, Universite Claude Bernard, 69373 Lyon, France
    Med Mal Infect 36:406-13. 2006
  4. pmc A systematic review and meta-analysis of evidence for correlation between molecular markers of parasite resistance and treatment outcome in falciparum malaria
    Stephane Picot
    Malaria Research Unit, EA 4170, University Lyon 1, Faculty of Medicine, Lyon, France
    Malar J 8:89. 2009
  5. doi request reprint [Plasmodium vivax infection: not so benign]
    Stephane Picot
    Malaria Research Unit, EA 4170, Faculte de Medecine, Universite Lyon 1, 8, avenue Rockefeller, 69373 Lyon Cedex 08, France
    Med Sci (Paris) 25:622-6. 2009
  6. pmc Safety of epoietin beta-quinine drug combination in children with cerebral malaria in Mali
    Stephane Picot
    Malaria Research Unit, EA 4170, University Lyon 1, Faculty of Medicine, Lyon, France
    Malar J 8:169. 2009
  7. ncbi request reprint Absence of nucleotide polymorphism in a Plasmodium vivax multidrug resistance gene after failure of mefloquine prophylaxis in French Guyana
    S Picot
    Laboratoire de Parasitologie, Mycologie Médicale et Maladies Tropicales, E A 3732, Universite Claude Bernard Lyon I, Lyon 69373, France
    Trans R Soc Trop Med Hyg 99:234-7. 2005
  8. pmc Plasmodium vivax resistance to chloroquine in Madagascar: clinical efficacy and polymorphisms in pvmdr1 and pvcrt-o genes
    Céline Barnadas
    EA4170, Parasitology and Tropical Medicine, 8 avenue Rockefeller, 69373 Lyon Cedex 08, France
    Antimicrob Agents Chemother 52:4233-40. 2008
  9. ncbi request reprint High prevalence and fixation of Plasmodium vivax dhfr/dhps mutations related to sulfadoxine/pyrimethamine resistance in French Guiana
    Céline Barnadas
    University Lyon 1, Malaria Research Unit, Lyon, France
    Am J Trop Med Hyg 81:19-22. 2009
  10. pmc Plasmodium vivax dhfr and dhps mutations in isolates from Madagascar and therapeutic response to sulphadoxine-pyrimethamine
    Céline Barnadas
    EA4170, Parasitology and Tropical Medicine, University Lyon 1, Lyon, France
    Malar J 7:35. 2008

Collaborators

Detail Information

Publications57

  1. ncbi request reprint Fluorogenic detection of viable Toxoplasma gondii
    E Borel
    Laboratoire de Parasitologie Mycologie Médicale et Pathologie Exotique, Universite Claude Bernard Lyon I
    Parasite 5:371-3. 1998
    ..Moreover, detection in culture are sensitive, easier, and less time consuming than previous methods. So, they should to be useful in strains behaviour analysis...
  2. ncbi request reprint [Apoptosis and programmed cell death. Host parasite relationship new paradigm]
    S Picot
    L EA 37 32, Praticien, Virulence et résistance des Plasmodium, Faculte de Medecine, Universite Claude Bernard, Lyon, France
    Med Trop (Mars) 66:111-7. 2006
    ....
  3. ncbi request reprint [Is Plasmodium vivax still a paradigm for uncomplicated malaria?]
    S Picot
    EA 37 32, virulence et résistance de plasmodium, Faculté de médecine de Lyon, Universite Claude Bernard, 69373 Lyon, France
    Med Mal Infect 36:406-13. 2006
    ....
  4. pmc A systematic review and meta-analysis of evidence for correlation between molecular markers of parasite resistance and treatment outcome in falciparum malaria
    Stephane Picot
    Malaria Research Unit, EA 4170, University Lyon 1, Faculty of Medicine, Lyon, France
    Malar J 8:89. 2009
    ..The purpose of this systematic review was to determine the risk of treatment failure associated with specific polymorphisms in the parasite genome or gene copy number...
  5. doi request reprint [Plasmodium vivax infection: not so benign]
    Stephane Picot
    Malaria Research Unit, EA 4170, Faculte de Medecine, Universite Lyon 1, 8, avenue Rockefeller, 69373 Lyon Cedex 08, France
    Med Sci (Paris) 25:622-6. 2009
    ..The major issue addressed in that paper is to alert clinicians on the -potential severity of this "benign tertian fever"...
  6. pmc Safety of epoietin beta-quinine drug combination in children with cerebral malaria in Mali
    Stephane Picot
    Malaria Research Unit, EA 4170, University Lyon 1, Faculty of Medicine, Lyon, France
    Malar J 8:169. 2009
    ..In this context, a new adjunctive strategy using a neuroprotective drug: erythropoietin (epoietin-beta, Epo) was proposed...
  7. ncbi request reprint Absence of nucleotide polymorphism in a Plasmodium vivax multidrug resistance gene after failure of mefloquine prophylaxis in French Guyana
    S Picot
    Laboratoire de Parasitologie, Mycologie Médicale et Maladies Tropicales, E A 3732, Universite Claude Bernard Lyon I, Lyon 69373, France
    Trans R Soc Trop Med Hyg 99:234-7. 2005
    ..vivax, when added to previously reported chloroquine and atovaquone-proguanil failure, strengthens the case for re-evaluating drug policies for vivax malaria and the need for continuous research on molecular markers of drug resistance...
  8. pmc Plasmodium vivax resistance to chloroquine in Madagascar: clinical efficacy and polymorphisms in pvmdr1 and pvcrt-o genes
    Céline Barnadas
    EA4170, Parasitology and Tropical Medicine, 8 avenue Rockefeller, 69373 Lyon Cedex 08, France
    Antimicrob Agents Chemother 52:4233-40. 2008
    ..The 976Y pvmdr1 mutation was found not to be useful for monitoring CQ resistance. Further efforts are required to develop suitable tools for monitoring drug resistance in P. vivax malaria...
  9. ncbi request reprint High prevalence and fixation of Plasmodium vivax dhfr/dhps mutations related to sulfadoxine/pyrimethamine resistance in French Guiana
    Céline Barnadas
    University Lyon 1, Malaria Research Unit, Lyon, France
    Am J Trop Med Hyg 81:19-22. 2009
    ..3%). No significant differences were observed between the prevalence of haplotypes and the year of collection. Our results indicate that, in this area, the fixation of SP drug-resistant parasites in the P. vivax population is stable...
  10. pmc Plasmodium vivax dhfr and dhps mutations in isolates from Madagascar and therapeutic response to sulphadoxine-pyrimethamine
    Céline Barnadas
    EA4170, Parasitology and Tropical Medicine, University Lyon 1, Lyon, France
    Malar J 7:35. 2008
    ..vivax infection and the polymorphisms in the pvdhfr and pvdhps genes were investigated. The correlation between these polymorphisms and clinical and parasitological responses was also investigated in P. vivax-infected patients...
  11. ncbi request reprint Characterization of an excreted/secreted antigen form of 14-3-3 protein in Toxoplasma gondii tachyzoites
    Olga Assossou
    Laboratoire de Parasitologie, Mycologie Medicale et Pathologie Exotique, Equipe d accueil 3087 Faculté de Médecine, Universite Claude Bernard, 8 avenue Rockefeller, 69373 Lyon, France
    FEMS Microbiol Lett 234:19-25. 2004
    ..A positive immunoreactivity was observed with sera corresponding to acute toxoplasmosis and a possible involvement of 14-3-3 in host immunity is discussed...
  12. ncbi request reprint Fitness of Toxoplasma gondii is not related to DHFR single-nucleotide polymorphism during congenital toxoplasmosis
    Francois Peyron
    E A 3732, Parasitology Unit, Faculty of Medicine, Claude Bernard University, Lyon, France
    Int J Parasitol 34:1169-75. 2004
    ..We concluded that the DHFR gene mutations we investigated do not regulate T. gondii fitness in humans...
  13. ncbi request reprint In vitro antimalarial activity of flavonoid derivatives dehydrosilybin and 8-(1;1)-DMA-kaempferide
    Frederique de Monbrison
    E A 3732, Universite Claude Bernard Lyon I, Laboratoire de Parasitologie, Mycologie Médicale et Maladies Tropicales, 8 avenue Rockefeller, 69373 Lyon Cedex 08, France
    Acta Trop 97:102-7. 2006
    ..Since this drug family has been largely used and well-tolerated in humans, flavonoid derivatives could be in the near future associated with already available drugs in order to delay the spread of P. falciparum resistance...
  14. pmc Plasmodium falciparum metacaspase PfMCA-1 triggers a z-VAD-fmk inhibitable protease to promote cell death
    Benoit Meslin
    Malaria Research Unit, ICBMS UMR 5246 CNRS UCBL1 INSA, Lyon, France
    PLoS ONE 6:e23867. 2011
    ....
  15. ncbi request reprint Features of apoptosis in Plasmodium falciparum erythrocytic stage through a putative role of PfMCA1 metacaspase-like protein
    Benoit Meslin
    University Claude Bernard Lyon 1, Equipe d Acceuil 41 70, Paristology and Tropical Medicine, Faculty of Medicine, Lyon, 69373, France
    J Infect Dis 195:1852-9. 2007
    ..This putative P. falciparum metacaspase protein has been designated PfMCA1. Our findings offer important insights into parasite survival strategies that could open new ways for therapeutic alternatives to drug resistance...
  16. ncbi request reprint Simultaneous identification of the four human Plasmodium species and quantification of Plasmodium DNA load in human blood by real-time polymerase chain reaction
    Frederique de Monbrison
    Parasitologie, Mycologie Médicale et Maladies Tropicales, Hospices Civils de Lyon, E A 3087, Universite Claude Bernard Lyon I, Lyon 69373, France
    Trans R Soc Trop Med Hyg 97:387-90. 2003
    ..Quantitative real-time PCR could also be used for the follow-up of patients during drug resistance studies managed by national malaria programmes, the testing of new drugs, and vaccine trials...
  17. pmc Therapeutic efficacy of artemether-lumefantrine for Plasmodium vivax infections in a prospective study in Guyana
    Daniel Eibach
    Malaria Research Unit, CNRS UMR 5246, University Lyon 1, Faculty of Medicine, Lyon, France
    Malar J 11:347. 2012
    ..A therapeutic efficacy study was conducted using artemether-lumefantrine + primaquine against P. vivax to evaluate a treatment alternative for chloroquine...
  18. ncbi request reprint Real-time PCR for chloroquine sensitivity assay and for pfmdr1-pfcrt single nucleotide polymorphisms in Plasmodium falciparum
    Frederique de Monbrison
    Laboratoire de Parasitologie, Mycologie Med et Pathologie Exotique, Hospices Civils de Lyon, Faculte de Medecine, Universite Claude Bernard, E A 3087, Lyon, France
    J Microbiol Methods 54:391-401. 2003
    ....
  19. doi request reprint Artesunate-erythropoietin combination for murine cerebral malaria treatment
    Anne Lise Bienvenu
    University Lyon 1, EA 4170, Parasitology and Tropical Medicine, Faculty of Medicine, 8 avenue Rockefeller, 69373 Lyon Cedex 08, France
    Acta Trop 106:104-8. 2008
    ....
  20. ncbi request reprint Serotyping of Toxoplasma gondii in chronically infected pregnant women: predominance of type II in Europe and types I and III in Colombia (South America)
    Francois Peyron
    Laboratoire de Parasitologie, Mycologie Medicale et Pathologie Exotique, Equipe d Accueil E A 3732, Faculté de médecine de Lyon, 8 avenue Rockefeller, 69373 Lyon, France
    Microbes Infect 8:2333-40. 2006
    ..We demonstrated that, despite some limitation due to antigen and/or antibody specificity, serotyping is a promising assay to investigate the relationship between type of strain and severity of the disease...
  21. ncbi request reprint Multicenter proficiency study for detection of Toxoplasma gondii in amniotic fluid by nucleic acid amplification methods
    Karine Kaiser
    Parasitology Laboratory, Hopital de la Croix Rousse, Lyon, France
    Clin Chim Acta 375:99-103. 2007
    ..A proficiency panel was designed to assess the performance of nucleic acid amplification technologies for the detection of Toxoplasma gondii in amniotic fluid...
  22. ncbi request reprint Short report: prevalence and chloroquine sensitivity of Plasmodium malariae in Madagascar
    Céline Barnadas
    Parasitology and Tropical Medicine, University Lyon 1, Lyon, France
    Am J Trop Med Hyg 77:1039-42. 2007
    ..malariae infection...
  23. pmc Are protozoan metacaspases potential parasite killers?
    Benoit Meslin
    Malaria Research Unit, University Lyon 1, 8 avenue Rockefeller, 69373 Lyon Cedex 08, France
    Parasit Vectors 4:26. 2011
    ..The aim of this paper is to review current knowledge of protozoan parasite metacaspases within a drug targeting perspective...
  24. ncbi request reprint Real-time PCR assay for the identification of cutaneous Leishmania parasite species in Constantine region of Algeria
    Frederique de Monbrison
    Service de Parasitologie, Hopital E Herriot, Hospices Civils de Lyon, France
    Acta Trop 102:79-83. 2007
    ..2%) of the samples analyzed were positive. Sixty-one (5%) were related to L. major strain. These results indicate that PCR assay provides pleasant results with filter paper and represents a tool for the identification of old world CL...
  25. ncbi request reprint Introducing antisense oligonucleotides into Pneumocystis carinii
    Frederique de Monbrison
    Laboratoire de Parasitologie, Mycologie Medicale et Pathologie Exotique, Hospices Civils de Lyon, E A 3087, Universite Claude Bernard Lyon I, 69373, Cedex 08, Lyons, France
    J Microbiol Methods 50:211-3. 2002
    ..Antisense oligonucleotides have been successfully introduced by electroporation or direct uptake in order to downregulate the prohibitin negative function on cell cycle...
  26. ncbi request reprint Toxoplasma gondii: comparison of human CD34+ and monocyte-derived dendritic cells after parasite infection
    F Persat
    Laboratoire de Parasitologie, Mycologie Medicale et Pathologie Exotique, Universite Claude Bernard, Lyon 1, EA 37 32, 8 avenue Rockefeller, 69373 Lyon Cedex 08, France
    Exp Parasitol 115:103-6. 2007
    ..Under similar conditions, no significant difference was noticed between mature or immature mo-DC. These data indicated that CD34-DC represent an alternative model that allows migration assay of infected DC by T. gondii...
  27. ncbi request reprint Real time quantitative PCR and RT--PCR for analysis of Pneumocystis carinii hominis
    K Kaiser
    Laboratoire de Parasitologie, Mycologie Médicale et Maladies Tropicales Hospices Civils de Lyon EA 3087 Université C Bernard Lyon I 8, avenue Rockefeller 69373, Lyon Cedex 08, France
    J Microbiol Methods 45:113-8. 2001
    ..In this current study, we present a detailed description of these methods and their applications for analysis of P. carinii hominis...
  28. ncbi request reprint Disseminated cryptococcosis and histoplasmosis co-infection in a HIV-infected woman in France
    T Ferry
    Service des Maladies Infectieuses et Tropicales, Hopital de la Croix Rousse, 103 Grande Rue de la Croix Rousse, 69317 Lyon Cedex 04, France
    J Infect 51:e173-6. 2005
    ..Histoplasma antigen detection is not yet available in France but it could have a key role in the early diagnosis of disseminated histoplasmosis co-existing with a cryptococcal infection, especially in HIV-infected African people...
  29. pmc Toxoplasma gondii regulates recruitment and migration of human dendritic cells via different soluble secreted factors
    J Diana
    Universite Claude Bernard Lyon 1, Laboratoire E A 37 32, Clinique Dermatologique, Hopital Edouard Herriot, Lyon, France
    Clin Exp Immunol 141:475-84. 2005
    ..Taken together, these results suggest that T. gondii controls recruitment and migration of immature DC by different soluble factors and may induce a dysfunction in the host-specific immune response...
  30. pmc Detection of Pneumocystis carinii DNA in blood specimens from human immunodeficiency virus-infected patients by nested PCR
    M Rabodonirina
    Departement de Parasitologie et de Mycologie, Universite Claude Bernard, Lyon, France
    J Clin Microbiol 37:127-31. 1999
    ..In conclusion, P. carinii DNA may be detected in whole blood from HIV-infected patients, but the nature and the meaning of the circulating form of P. carinii remain to be established...
  31. ncbi request reprint Use of ivermectin for the management of scabies in a nursing home
    E Dannaoui
    Laboratoire de Parasitologie, Mycologie Medicale et Pathologie Exotique, Universite Claude Bernard Lyon I, 8, avenue Rockefeller, 69373 Lyon Cedex, France
    Eur J Dermatol 9:443-5. 1999
    ..In only one case, was there a failure of the treatment. It is concluded that oral ivermectin is an effective and practical therapy for scabies in nursing homes...
  32. ncbi request reprint In-vitro susceptibility of Aspergillus spp. isolates to amphotericin B and itraconazole
    E Dannaoui
    Laboratoire de Parasitologie, Mycologie Medicale et Pathologie Exotique, Universite Claude Bernard Lyon I, France
    J Antimicrob Chemother 44:553-5. 1999
    ..No isolate was detected with an MIC of amphotericin B >2 mg/L. Itraconazole MICs >16 mg/L were detected for four Aspergillus fumigatus and one Aspergillus nidulans isolates...
  33. ncbi request reprint Amphotericin B resistance of Aspergillus terreus in a murine model of disseminated aspergillosis
    E Dannaoui
    Laboratoire de Parasitologie, Mycologie Medicale et Pathologie Exotique, Universite Claude Bernard Lyon I, France
    J Med Microbiol 49:601-6. 2000
    ..Analysis of sterol composition showed that the major sterol was ergosterol. This suggests that amphotericin B resistance was not related to a modified sterol profile...
  34. ncbi request reprint Use of spectrophotometric reading for in vitro antifungal susceptibility testing of Aspergillus spp
    E Dannaoui
    Laboratoire de Parasitologie, Mycologie Medicale et Pathologie Exotique, Universite Claude Bernard Lyon I, France
    Can J Microbiol 45:871-4. 1999
    ..It is concluded that spectrophotometric MIC endpoint determination is a valuable alternative to the visual reference method for susceptibility testing of Aspergillus species...
  35. ncbi request reprint Acquired itraconazole resistance in Aspergillus fumigatus
    E Dannaoui
    Laboratoire de Parasitologie, Mycologie Medicale et Pathologie Exotique, Universite Claude Bernard Lyon I, 8 avenue Rockefeller, 69373 Lyon Cedex, France
    J Antimicrob Chemother 47:333-40. 2001
    ..RAPD patterns obtained with each of them were identical, suggesting that the same strain was recovered over time and had acquired resistance to itraconazole...
  36. ncbi request reprint Sterol composition of itraconazole-resistant and itraconazole-susceptible isolates of Aspergillus fumigatus
    E Dannaoui
    Laboratoire de Parasitologie, Mycologie Medicale et Pathologie Exotique, Universite Claude Bernard Lyon I, France
    Can J Microbiol 47:706-10. 2001
    ..These results suggest that itraconazole resistance is not related, for the strains studied, to alterations in the ergosterol synthesis pathway...
  37. ncbi request reprint Alveolar echinococcosis in a patient without hepatic disturbance and with unusual humoral immune response
    F Persat
    Laboratoire de Parasitologie, Mycologie Médicale et Maladies Tropicales, Faculte de Medecine, Hospices Civils de Lyon, 8 avenue Rockefeller, 69373, Lyon Cedex 08, France
    Eur J Clin Microbiol Infect Dis 23:859-60. 2004
  38. doi request reprint Estimation of the incubation period of invasive aspergillosis by survival models in acute myeloid leukemia patients
    Thomas Benet
    Epidemiology and Infection Control Unit, Edouard Herriot Hospital, Hospices Civils de Lyon, Lyon, France
    Med Mycol 51:214-8. 2013
    ..Overall, 53 patients had IA after aplasia, with the median observed time interval between the two being 15 days. Based on log-normal distribution, the median estimated IA incubation period was 14.6 days (95% CI; 12.8-16.5 days)...
  39. pmc Evaluation of the malaria rapid diagnostic test VIKIA malaria Ag Pf/Pan™ in endemic and non-endemic settings
    Daniel Eibach
    Institut de Parasitologie et de Mycologie Médicale, Faculty of Medicine, Hospices Civils de Lyon, Lyon, France
    Malar J 12:188. 2013
    ....
  40. pmc Binding of live conidia of Aspergillus fumigatus activates in vitro-generated human Langerhans cells via a lectin of galactomannan specificity
    F Persat
    EA 3087, Universite Claude Bernard, Lyon, France and Unité INSERM 346, Lyon, France
    Clin Exp Immunol 133:370-7. 2003
    ..Conidial binding was followed by activation and maturation of iLC, suggesting that LC present in the lung may play a role in cellular host defence against aspergilloses...
  41. doi request reprint Cerebral malaria: protection by erythropoietin
    Anne Lise Bienvenu
    Malaria Research Unit, SMITH ICBMS UMR CNRS, UCBL, INSA Lyon, Lyon, France
    Methods Mol Biol 982:315-24. 2013
    ..High doses of Epo are needed to cross the blood-brain barrier and to favor the cytoprotective versus hematopoietic effect of this pleiotropic cytokine...
  42. doi request reprint Cutaneous cryptococcosis in solid organ transplant recipients: epidemiological, clinical, diagnostic and therapeutic features
    Doriane Biancheri
    Department of Dermatology, Edouard Herriot Hospital Group, Lyon, France
    Eur J Dermatol 22:651-7. 2012
    ..Evidence of dissemination is difficult because of the poor sensitivity of diagnostic tests. Fluconazole was the treatment of choice in association with immunosuppressive treatment tapering...
  43. doi request reprint Risk factors for invasive aspergillosis in acute myeloid leukemia patients prophylactically treated with posaconazole
    Mauricette Michallet
    Department of Hematology, Hopital Edouard Herriot, Hospices Civils de Lyon, Lyon, France
    Med Mycol 49:681-7. 2011
    ..Patient's age and response to induction treatment are two independent infection risk factors, and need more attention during future clinical trials linked to antifungal prophylaxis...
  44. pmc Contribution of the (1-->3)-beta-D-glucan assay for diagnosis of invasive fungal infections
    Florence Persat
    Service de Parasitologie, Mycologie Médicale et Maladies Tropicales, Hopital Edouard Herriot, Hospices Civils de Lyon, Domaine Rockefeller, 8 avenue Rockefeller, 69373 Lyon, Cedex 08, France
    J Clin Microbiol 46:1009-13. 2008
    ....
  45. ncbi request reprint Subcellular localization of 14-3-3 proteins in Toxoplasma gondii tachyzoites and evidence for a lipid raft-associated form
    Olga Assossou
    Laboratoire de Parasitologie, Mycologie Medicale et Pathologie Exotique, Equipe d accueil EA 3087 Faculté de Médecine, Universite Claude Bernard, 8 avenue Rockefeller, 69373, Lyon, Cedex 08, France
    FEMS Microbiol Lett 224:161-8. 2003
    ..Two 14-3-3 isoforms were detected. The major one was mainly cytoplasmic and to a lesser extent membrane-associated, whereas the minor isoform was associated with the detergent-resistant lipid rafts...
  46. pmc Apoptosis induced by parasitic diseases
    Anne Lise Bienvenu
    Malaria Research Unit, University Lyon 1, 8 avenue Rockefeller, 69373 Lyon Cedex 08, France
    Parasit Vectors 3:106. 2010
    ..An important issue will be to predict the beneficial or deleterious effects of controlling human cell death by apoptotic-like mechanisms during parasitic diseases...
  47. pmc Heterogeneity in cellular and humoral immune responses against Toxoplasma gondii antigen in humans
    A F Fatoohi
    E A 3087 Parasitologie, Faculté de Médecine Lyon Nord, and Laboratoire d Immunologie, Hopital de la Croix Rousse, Lyon, France
    Clin Exp Immunol 136:535-41. 2004
    ..However, only two proteins in the 20-40 kD range induced a significant humoral response. Further studies are necessary to determine which proteins in the Fr 26-31.9 kD and 32-36.9 kD are superior immunogens for cellular responses...
  48. pmc Cellular immune responses to recombinant antigens in pregnant women chronically infected with Toxoplasma gondii
    A F Fatoohi
    E A 3087 Parasitologie, Faculté de Médecine Lyon Nord, Lyon, France
    Clin Diagn Lab Immunol 9:704-7. 2002
    ..Interleukin-4 was always absent from supernatants of cells stimulated with toxoplasma antigens. The heterogeneity of human responses to individual recombinant toxoplasma antigens should be considered in the design of potential vaccines...
  49. ncbi request reprint Comparative diagnostic performance of two commercial rapid tests for malaria in a non-endemic area
    F de Monbrison
    Service de parasitologie et mycologie médicale, 8 avenue Rockefeller, 69373 Lyon Cedex 08, France
    Eur J Clin Microbiol Infect Dis 23:784-6. 2004
    ..falciparum infections, and it generated seven false-positive results. The results suggest that these rapid diagnostic tests for malaria may be useful, but they cannot replace microscopic examination of blood films...
  50. doi request reprint Microbiologic identification of bleb-related delayed-onset endophthalmitis caused by moraxella species
    Pierre Loic Cornut
    Department of Ophthalmology, University Hospital, Claude Bernard University, Hopital Edouard Herriot, Lyon, France
    J Glaucoma 17:541-5. 2008
    ..To report the clinical presentation and outcome of delayed-onset endophthalmitis caused by Moraxella species and to evaluate the eubacterial polymerase chain reaction (PCR) in aqueous humor samples for the microbiologic diagnosis...
  51. ncbi request reprint [Real-time PCR for detection of molecular markers of resistance in Plasmodium falciparum]
    F de Monbrison
    Laboratoire de Parasitologie, Mycologie Medicale et Pathologie Exotique, E A 3087, Faculte de Medecine, Universite Claude Bernard, 8, avenue Rockefeller, 69373 Lyon cedex 03, France
    Pathol Biol (Paris) 51:528-33. 2003
    ..The aim of this study was not to provide definitive data concerning the rate of mutations in an endemic area, but to describe a powerful method allowing the detection of major pfmdr1 and pfcrt mutations...
  52. ncbi request reprint Evaluation of different commercial ELISA methods for the serodiagnosis of systemic candidosis
    F Persat
    Service de Parasitologie, Mycologie Médicale et Maladies Tropicales, and Service d Hématologie, Hopital Edouard Herriot, Lyon, France
    Mycoses 45:455-60. 2002
    ..4% versus 59%, respectively) with a specificity of 52.6% (versus 55.2%). Interest in the use of commercial ELISAs, more particularly the Platelia tests, has to be confirmed in a prospective study with follow-up of the patients...
  53. ncbi request reprint Candida species distribution in bloodstream cultures in Lyon, France, 1998-2001
    D Martin
    Laboratoire de parasitologie et mycologie médicale, Hopital Edouard Herriot, Hospices Civils de Lyon, 8 avenue Rockefeller, 69373 Lyon Cedex 08, France
    Eur J Clin Microbiol Infect Dis 24:329-33. 2005
    ..Since C. krusei has inherent resistance to the antifungal agent fluconazole, prophylactic use of fluconazole in these patients was investigated, but no relationship between these two parameters was found...
  54. doi request reprint [New use of primaquine for malaria]
    M Oliver
    Laboratoire de Biochimie, Hôpital d Instruction des Armées Laveran, Marseille, France
    Med Mal Infect 38:169-79. 2008
    ..vivax or P. ovale. In France, primaquine is not approved for prevention and treatment and its use requires a specific temporary authorization...
  55. ncbi request reprint Synergistic and antagonistic interactions between haemozoin and bacterial endotoxin on human and mouse macrophages
    N Basilico
    Istituto di Microbiologia, Universita di Milano, Milan, Italy
    Parassitologia 45:135-40. 2003
    ..These data rise the question of whether and how in vivo concomitant gram(-) bacteremia may affect the pathogenesis and/or the immune response of malaria infections and vice versa...
  56. ncbi request reprint Severe peritonitis due to Balantidium coli acquired in France
    T Ferry
    Service de Medecine Interne et Maladies Infectieuses, Hôpital de Fleyriat, 01012 Bourg en Bresse, France
    Eur J Clin Microbiol Infect Dis 23:393-5. 2004
    ..Specific antibiotic treatment is efficacious, and it is important to consider the risk of this parasitic disease in susceptible patients presenting with bloody diarrhoea...
  57. ncbi request reprint Black piedra: report of a French case associated with Trichosporon asahii
    J Kanitakis
    Int J Dermatol 45:1258-60. 2006