R Peyron

Summary

Country: France

Publications

  1. doi request reprint [Functional brain mapping of pain perception]
    Roland Peyron
    Département de Neurologie et Centre de la Douleur, CHU, F 42055 Saint Etienne, INSERM U879, UCBL Lyon 1, UJM Saint Étienne, F 42023 Saint Etienne, France
    Med Sci (Paris) 27:82-7. 2011
  2. doi request reprint Mechanical allodynia in neuropathic pain. Where are the brain representations located? A positron emission tomography (PET) study
    R Peyron
    Department of Neurology, Pain Center, CHU de Saint Etienne, France
    Eur J Pain 17:1327-37. 2013
  3. ncbi request reprint [Pathophysiology of chronic pain. Classification of three subtypes of pain]
    Roland Peyron
    Service de Neurologie, Hopital Nord, CHU de Saint Etienne, INSERM U1028, CNRL Lyon, 42277 Saint Priest en Jarez Cedex, France
    Rev Prat 63:773-8. 2013
  4. doi request reprint Modulations of pain sensations
    R Peyron
    U1028 Inserm, Central Integration of Pain, Neuroscience Research Center, Saint Etienne, France
    Neurophysiol Clin 42:293-8. 2012
  5. ncbi request reprint Central representation of the RIII flexion reflex associated with overt motor reaction: an fMRI study
    R Peyron
    Departement de Neurologie, CHU de St Etienne, 42055 St Etienne, France
    Neurophysiol Clin 37:249-59. 2007
  6. ncbi request reprint Motor cortex stimulation in neuropathic pain. Correlations between analgesic effect and hemodynamic changes in the brain. A PET study
    Roland Peyron
    Department of Neurology, CHU Saint Etienne, France
    Neuroimage 34:310-21. 2007
  7. ncbi request reprint An fMRI study of cortical representation of mechanical allodynia in patients with neuropathic pain
    R Peyron
    Departement de Neurologie, Hopital de Bellevue, Bd Pasteur, 42055 Saint Etienne, France
    Neurology 63:1838-46. 2004
  8. ncbi request reprint Role of operculoinsular cortices in human pain processing: converging evidence from PET, fMRI, dipole modeling, and intracerebral recordings of evoked potentials
    R Peyron
    Clinical Neurophysiology and Epileptology Department, Lyon, France
    Neuroimage 17:1336-46. 2002
  9. ncbi request reprint Electrical stimulation of motor cortex for pain control: a combined PET-scan and electrophysiological study
    L Garcia-Larrea
    Functional Neurology Unit, UPRES EA 1880, Claude Bernard University, and Institut Fédératif de Neurosciences of Lyon IFNL, Lyon, France
    Pain 83:259-73. 1999
  10. ncbi request reprint Parietal and cingulate processes in central pain. A combined positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) study of an unusual case
    R Peyron
    Neurological Department, Bellevue Hospital, 42055, Saint Etienne, France
    Pain 84:77-87. 2000

Collaborators

Detail Information

Publications40

  1. doi request reprint [Functional brain mapping of pain perception]
    Roland Peyron
    Département de Neurologie et Centre de la Douleur, CHU, F 42055 Saint Etienne, INSERM U879, UCBL Lyon 1, UJM Saint Étienne, F 42023 Saint Etienne, France
    Med Sci (Paris) 27:82-7. 2011
    ..Interestingly, these activations may correlate with the magnitude of pain relief, with the activation of the PAG, and, at least in some instances, with the involvement of endogenous opioids...
  2. doi request reprint Mechanical allodynia in neuropathic pain. Where are the brain representations located? A positron emission tomography (PET) study
    R Peyron
    Department of Neurology, Pain Center, CHU de Saint Etienne, France
    Eur J Pain 17:1327-37. 2013
    ..The same is not true for allodynic pain in patients with neuropathic pain since the cortical reorganizations that are involved in the conversion of non-noxious stimuli into painful sensations still remain unknown...
  3. ncbi request reprint [Pathophysiology of chronic pain. Classification of three subtypes of pain]
    Roland Peyron
    Service de Neurologie, Hopital Nord, CHU de Saint Etienne, INSERM U1028, CNRL Lyon, 42277 Saint Priest en Jarez Cedex, France
    Rev Prat 63:773-8. 2013
    ..These are the cases of dysfunctional pain...
  4. doi request reprint Modulations of pain sensations
    R Peyron
    U1028 Inserm, Central Integration of Pain, Neuroscience Research Center, Saint Etienne, France
    Neurophysiol Clin 42:293-8. 2012
    ..These findings are discussed with regard to previous literature of pain modulations but also with regard to the concept of the "pain matrix", its inputs and the temporal dynamics of its constitutive responses...
  5. ncbi request reprint Central representation of the RIII flexion reflex associated with overt motor reaction: an fMRI study
    R Peyron
    Departement de Neurologie, CHU de St Etienne, 42055 St Etienne, France
    Neurophysiol Clin 37:249-59. 2007
    ..They should be considered as a motor component of pain-related processes activated in case of intense pain...
  6. ncbi request reprint Motor cortex stimulation in neuropathic pain. Correlations between analgesic effect and hemodynamic changes in the brain. A PET study
    Roland Peyron
    Department of Neurology, CHU Saint Etienne, France
    Neuroimage 34:310-21. 2007
    ..These hemodynamic changes are lengthened and might therefore underlie the long-lasting clinical effects that largely outlast the actual stimulation periods...
  7. ncbi request reprint An fMRI study of cortical representation of mechanical allodynia in patients with neuropathic pain
    R Peyron
    Departement de Neurologie, Hopital de Bellevue, Bd Pasteur, 42055 Saint Etienne, France
    Neurology 63:1838-46. 2004
    ..To investigate cerebral activity associated with allodynia in patients with neuropathic pain...
  8. ncbi request reprint Role of operculoinsular cortices in human pain processing: converging evidence from PET, fMRI, dipole modeling, and intracerebral recordings of evoked potentials
    R Peyron
    Clinical Neurophysiology and Epileptology Department, Lyon, France
    Neuroimage 17:1336-46. 2002
    ....
  9. ncbi request reprint Electrical stimulation of motor cortex for pain control: a combined PET-scan and electrophysiological study
    L Garcia-Larrea
    Functional Neurology Unit, UPRES EA 1880, Claude Bernard University, and Institut Fédératif de Neurosciences of Lyon IFNL, Lyon, France
    Pain 83:259-73. 1999
    ..In contrast, the hypothesis of somatosensory cortex activation by MCS could not be confirmed by our results...
  10. ncbi request reprint Parietal and cingulate processes in central pain. A combined positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) study of an unusual case
    R Peyron
    Neurological Department, Bellevue Hospital, 42055, Saint Etienne, France
    Pain 84:77-87. 2000
    ..This response is likely to be responsible for the strange and very unpleasant allodynic sensation elicited on the left side by a non-noxious stimulation...
  11. ncbi request reprint Motor cortex stimulation for pain control induces changes in the endogenous opioid system
    J Maarrawi
    INSERM U879, Bron, France
    Neurology 69:827-34. 2007
    ..We studied the possible contribution of the endogenous opioid system to MCS-related pain relief...
  12. ncbi request reprint Effects of GABAA receptors activation on brain glucose metabolism in normal subjects and temporal lobe epilepsy (TLE) patients. A positron emission tomography (PET) study. Part II: The focal hypometabolism is reactive to GABAA agonist administration in TL
    R Peyron
    Centre d Exploration et de Recherches Médicales par Emission de Positions, Lyon, France
    Epilepsy Res 19:55-62. 1994
    ..This metabolic response in the hypometabolic focus, observed in the absence of any epileptic discharge during FDG accumulation and PET data acquisition, suggests that GABAA receptors are up-regulated or, at least, preserved in TLE...
  13. ncbi request reprint Cognitive effects of precentral cortical stimulation for pain control: an ERP study
    C Montes
    Equipe d Accueil, EA1880 UCB, Lyon, France
    Neurophysiol Clin 32:313-25. 2002
    ....
  14. ncbi request reprint Allodynia after lateral-medullary (Wallenberg) infarct. A PET study
    R Peyron
    Neurological Department, Bellevue Hospital, Saint Etienne, France
    Brain 121:345-56. 1998
    ....
  15. ncbi request reprint Haemodynamic brain responses to acute pain in humans: sensory and attentional networks
    R Peyron
    Departement de Neurologie and Centre de la douleur, Hopital de Bellevue, Saint Etienne, France
    Brain 122:1765-80. 1999
    ..Attentional processes could possibly explain part of the variability observed in previous PET reports and should therefore be considered in further studies on pain in both normal subjects and patients with chronic pain...
  16. ncbi request reprint Functional imaging and neurophysiological assessment of spinal and brain therapeutic modulation in humans
    L Garcia-Larrea
    Functional Neurology Unit, UPRES EA 1880, Claude Bernard University, Affiliated with the Institut Fédératif de Neurosciences of Lyon IFNL, Lyon, France
    Arch Med Res 31:248-57. 2000
    ..The combination of clinical electrophysiology and functional neuroimaging provides insight into the mechanisms of action of neuromodulation procedures, guides clinical decision, and contributes to optimize patient selection...
  17. doi request reprint Somatotopic organization of pain responses to direct electrical stimulation of the human insular cortex
    L Mazzola
    INSERM U 879 Central Integration of Pain, Lyon, St Etienne, France
    Pain 146:99-104. 2009
    ..These data suggest that, in spite of large and often bilateral receptive fields, pain representation shows some degree of somatotopic organization in the human insula...
  18. doi request reprint Modulation of laser-evoked potentials and pain perception by transcutaneous electrical nerve stimulation (TENS): a placebo-controlled study in healthy volunteers
    François Vassal
    Service de Neurochirurgie, Hopital Nord, Centre Hospitalier Régional Universitaire de Saint Etienne, France
    Clin Neurophysiol 124:1861-7. 2013
    ..To investigate the effects of transcutaneous electrical nerve stimulation (TENS) on brain nociceptive responses (laser-evoked potentials, LEPs) and pain perception...
  19. ncbi request reprint Positron emission tomography during motor cortex stimulation for pain control
    L Garcia-Larrea
    CERMEP Positron Emission Tomography Center, Lyon, France
    Stereotact Funct Neurosurg 68:141-8. 1997
    ..Such effects may be obtained only if thalamic activation reaches a 'threshold' level, below which the analgesic cascade would not be successfully triggered...
  20. ncbi request reprint Electrical stimulation of precentral cortical area in the treatment of central pain: electrophysiological and PET study
    R Peyron
    Department of Neurology, Bellevue Hospital, Etienne, France
    Pain 62:275-86. 1995
    ..Painful dysesthesiae during stimulation have to be distinguished from other innocuous sensory side effects, since they may compromise PGS efficacy...
  21. ncbi request reprint The role of parietal opercular and insular cortex in pain sensation in humans: data from PET activation studies and intracortical recordings of CO2 laser evoked potentials (LEPs)
    F Mauguiere
    Functional Neurology and Epileptology Department, Neurological Hospital, Lyon, France
    Electroencephalogr Clin Neurophysiol Suppl 49:255-60. 1999
  22. doi request reprint [Central post-stroke pain]
    S Demasles
    Centre stéphanois de la douleur et service de neurologie, Hopital de Bellevue, 42055 Saint Etienne Cedex 02, France
    Rev Neurol (Paris) 164:825-31. 2008
    ..The thalamus plays a prominent role in this disorder of central control of pain...
  23. doi request reprint Pain relief by rTMS: differential effect of current flow but no specific action on pain subtypes
    N Andre-Obadia
    INSERM U879, University Claude Bernard Lyon 1, France
    Neurology 71:833-40. 2008
    ..To assess, against placebo, the pain-relieving effects of high-rate repetitive transcranial magnetic stimulation (rTMS) on neuropathic pain...
  24. doi request reprint Episodic ataxia type 2: unusual aspects in clinical and genetic presentation. Special emphasis in childhood
    P Bertholon
    Service ORL, Pavillon 50, Hopital Bellevue, Bvd Pasteur, CHU Saint Etienne, France
    J Neurol Neurosurg Psychiatry 80:1289-92. 2009
    ..To describe aspects in clinical and genetic presentation in five patients with episodic ataxia type 2 (EA2)...
  25. doi request reprint In-patient versus out-patient withdrawal programmes for medication overuse headache: a 2-year randomized trial
    C Créac'h
    North University Hospital, France
    Cephalalgia 31:1189-98. 2011
    ..Medication-overuse headache (MOH) management usually includes a medication withdrawal. The choice of withdrawal modalities remains a matter of debate...
  26. doi request reprint How a clock can change your pain? The illusion of duration and pain perception
    Florence B Pomares
    Department of Neurology, CHU, 42055 Saint Etienne, France
    Pain 152:230-4. 2011
    ..This study suggests that the perceived duration of a noxious stimulation may influence the perceived intensity of pain. The perceived duration of the length of a noxious stimulation influences (decreases) the intensity of perceived pain...
  27. doi request reprint Positional cluster-like headache. A case report of a neurovascular compression between the third cervical root and the vertebral artery
    Christelle Créac'h
    Universite Lyon 1, France
    Cephalalgia 30:1509-13. 2010
    ..The excellent outcome after microvascular cervical decompression suggests a causal relationship between the cluster-like headache and the vertebral constraint on the C3 root...
  28. doi request reprint Pneumatic evoked potential. Sensory or auditive potential?
    S Conde
    Department of Neurology, Neurophysiology and Pain Center, University Hospital, 42055 Saint Etienne, France
    Neurophysiol Clin 43:189-95. 2013
    ..In this study, evoked potentials (EPs) to a pneumatic, innocuous, and calibrated stimulation of the skin were recorded in 22 volunteers...
  29. ncbi request reprint [Positron emission tomography to study central pain integration]
    B Laurent
    Service de Neurologie de Saint Etienne et Centre stéphanois de la douleur, Lyon, France
    Rev Neurol (Paris) 156:341-51. 2000
    ..To advance our knowledge of the mechanisms generating both abnormal pain and analgesia (drugs and surgical techniques) in patients is the main motivation of such anexciting challenge...
  30. ncbi request reprint Effects of GABAA receptors activation on brain glucose metabolism in normal subjects and temporal lobe epilepsy (TLE) patients. A positron emission tomography (PET) study. Part I: Brain glucose metabolism is increased after GABAA receptors activation
    R Peyron
    Centre d Exploration et de Recherches Médicales par Emission de Positons, Lyon, France
    Epilepsy Res 19:45-54. 1994
    ....
  31. ncbi request reprint Functional imaging of brain responses to pain. A review and meta-analysis (2000)
    R Peyron
    Departement de Neurologie, Hopital de Bellevue, boulevard Pasteur, 42055 Saint Etienne, France
    Neurophysiol Clin 30:263-88. 2000
    ..The precise biochemical nature of these mechanisms remains to be investigated...
  32. ncbi request reprint Transcranial magnetic stimulation for pain control. Double-blind study of different frequencies against placebo, and correlation with motor cortex stimulation efficacy
    Nathalie Andre-Obadia
    University Hospital Lyon Sud, Lyon, France
    Clin Neurophysiol 117:1536-44. 2006
    ..To assess, using a double-blind procedure, the pain-relieving effects of rTMS against placebo, and their predictive value regarding the efficacy of implanted motor cortex stimulation (MCS)...
  33. ncbi request reprint Motor cortex stimulation for refractory neuropathic pain: four year outcome and predictors of efficacy
    Christophe Nuti
    Department of Neurosurgery, CHU Saint Etienne, Bd Pasteur, 42055 Saint Etienne Cedex 2, France
    Pain 118:43-52. 2005
    ..744; p<0.0001). These results confirm that MCS can be a satisfactory and durable alternative to medical treatments in patients with refractory pain, and suggest that the efficacy of MCS may be predicted in the first month of therapy...
  34. doi request reprint Operculo-insular pain (parasylvian pain): a distinct central pain syndrome
    Luis Garcia-Larrea
    Central Integration of Pain Unit, U879 INSERM and University Claude Bernard, Lyon 1, Neurological Hospital, Lyon, France
    Brain 133:2528-39. 2010
    ..Parasylvian pain may be extremely difficult to treat; the magnitude of pain-temperature sensory disturbances may be prognostic for its development, hence the importance of early sensory assessment with quantitative methods...
  35. ncbi request reprint Laser-evoked potential abnormalities in central pain patients: the influence of spontaneous and provoked pain
    Luis Garcia-Larrea
    INSERM and Laboratoire de neurophysiologie humaine du CERMEP, Lyon, France
    Brain 125:2766-81. 2002
    ..In selected contexts (pain sine materia, non-organic anaesthesia), normal or enhanced LEPs may support a psychogenic participation in the syndrome...
  36. doi request reprint Organic background of restrictive-type anorexia nervosa suggested by increased serotonin 1A receptor binding in right frontotemporal cortex of both lean and recovered patients: [18F]MPPF PET scan study
    Bogdan Galusca
    Endocrinology Department, CHU Saint Etienne, France
    Biol Psychiatry 64:1009-13. 2008
    ..4-(2-methoxyphenyl)-1-[2-(N-2-pyridinyl)-p-fluorobenzamido]-ethylpiperazine ([(18)F]MPPF) is a selective 5-HT(1A) receptor antagonist with an affinity close to that of endogenous 5-HT...
  37. ncbi request reprint [Introduction to pain pathophysiology. Applications to visceral pain]
    Patrice Queneau
    Service de Médecine Interne et Thérapeutique, CHU de Saint Etienne
    Gastroenterol Clin Biol 27:S59-67. 2003
  38. ncbi request reprint On the relation between sensory deafferentation, pain and thalamic activity in Wallenberg's syndrome: a PET-scan study before and after motor cortex stimulation
    Luis Garcia-Larrea
    INSERM E342, Central Integration of Human Pain, Hopital Neurologique, 59 Bd Pinel, 69003 Lyon, France Université Claude Bernard Lyon1, France
    Eur J Pain 10:677-88. 2006
    ..Restoration of thalamic activity in neuropathic pain might represent one important condition to obtain successful relief by analgesic procedures, including cortical neurostimulation...
  39. ncbi request reprint Motor cortex stimulation for neuropathic pain: From phenomenology to mechanisms
    Luis Garcia-Larrea
    Central Integration of Pain Inserm U 879, F 69677, France
    Neuroimage 37:S71-9. 2007
    ..This, along with the delayed and long-lasting activation of several brain structures, is consistent with the clinical effects of MCS, which may also last for hours or days after MCS discontinuation...
  40. ncbi request reprint Differential brain opioid receptor availability in central and peripheral neuropathic pain
    Joseph Maarrawi
    INSERM EMI 342 Central Integration of pain, 59 Bd Pinel, 69394 Lyon and St Etienne, France
    Pain 127:183-94. 2007
    ..Central and peripheral forms of NP may differ in distribution of brain opioid system changes and this in turn might underlie their different sensitivity to opiates...