Bernard Payrastre

Summary

Country: France

Publications

  1. pmc A novel mass assay to quantify the bioactive lipid PtdIns3P in various biological samples
    Gaëtan Chicanne
    INSERM, U1048 and Université Toulouse 3, I2MC, Avenue Jean Poulhès BP84225, 31432 Toulouse cedex 04, France
    Biochem J 447:17-23. 2012
  2. doi request reprint Phosphoinositides and cellular pathogens
    Bernard Payrastre
    INSERM, U1048, Université Toulouse 3, I2MC, Hôpital de Toulouse, BP 84225 Avenue Jean Poulhès, 31432, Toulouse cedex 04, France
    Subcell Biochem 59:363-88. 2012
  3. doi request reprint Regulation and roles of PI3Kβ, a major actor in platelet signaling and functions
    Marie Pierre Gratacap
    INSERM, U563, Universite Toulouse III, Centre de Physiopathologie de Toulouse Purpan, CHU Purpan, Toulouse, France
    Adv Enzyme Regul 51:106-16. 2011
  4. doi request reprint Shigella flexneri infection generates the lipid PI5P to alter endocytosis and prevent termination of EGFR signaling
    Damien Ramel
    INSERM, U1048, Université Toulouse 3, I2MC and Hôpital de Toulouse, Avenue Jean Poulhès BP84225, 31432 Toulouse cedex 04, France
    Sci Signal 4:ra61. 2011
  5. doi request reprint Chronic estradiol treatment reduces platelet responses and protects mice from thromboembolism through the hematopoietic estrogen receptor α
    Marie Cecile Valera
    INSERM, U1048 and Université Toulouse 3, I2MC, Toulouse, France
    Blood 120:1703-12. 2012
  6. ncbi request reprint Phosphatidylinositol 5-phosphate regulates invasion through binding and activation of Tiam1
    Julien Viaud
    INSERM, UMR1048, Universite Toulouse III, Institut des Maladies Métaboliques et Cardiovasculaires, 31432 Toulouse, France
    Nat Commun 5:4080. 2014
  7. doi request reprint Deletion of the p110beta isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo
    Valerie Martin
    INSERM, U563, Centre de Physiopathologie de Toulouse Purpan, Département d Oncogenèse, Signalisation et Innovation thérapeutique, and Université Toulouse III Paul Sabatier, Toulouse, France
    Blood 115:2008-13. 2010
  8. doi request reprint Inherited platelet disorders and oral health
    Marie Cecile Valera
    INSERM, U1048, Université Toulouse 3, I2MC, Equipe 11, CHU Rangueil, Toulouse, France
    J Oral Pathol Med 42:115-24. 2013
  9. doi request reprint Regulation of the DH-PH tandem of guanine nucleotide exchange factor for Rho GTPases by phosphoinositides
    Julien Viaud
    INSERM, UMR1048, Universite Paul Sabatier, Institut des Maladies Métaboliques et Cardiovasculaires, I2MC, 1 avenue Jean Poulhes, BP 84225, 31432 Toulouse Cedex 4, France
    Adv Biol Regul 52:303-14. 2012
  10. pmc The nucleophosmin-anaplastic lymphoma kinase oncogene interacts, activates, and uses the kinase PIKfyve to increase invasiveness
    Sophie Dupuis-Coronas
    INSERM, U1048, I2MC, Universite Toulouse III Paul Sabatier, Centre Hospitalier Universitaire de Toulouse, Toulouse Cedex 4, France
    J Biol Chem 286:32105-14. 2011

Collaborators

  • Damien Ramel
  • Pierre Sie
  • Olivier Pertz
  • Bart Vanhaesebroeck
  • Francoise Lenfant
  • Christian Recher
  • Pierre Gourdy
  • Jean Francois Arnal
  • Gaëtan Chicanne
  • Frédérique Gaits-Iacovoni
  • Marie Pierre Gratacap
  • Julien Viaud
  • Marie Cecile Valera
  • Hélène Tronchère
  • Valerie Martin
  • Frédéric Lagarrigue
  • François Vergez
  • Cendrine Cabou
  • Sophie Dupuis-Coronas
  • Julie Guillermet-Guibert
  • Sophie Allart
  • Laurie Ceccato
  • Delphine Courilleau
  • Jean Marie Xuereb
  • Philippe Kemoun
  • Sarah Cousty
  • Céline E Toutain
  • Michel Sixou
  • Marlène Marcellin
  • Anne Dominique Terrisse
  • Nathalie Saint Laurent
  • Cécile Boscheron
  • Sonia Severin
  • Estelle Saland
  • Monique Plantavid
  • Martine Jandrot-Perrus

Detail Information

Publications11

  1. pmc A novel mass assay to quantify the bioactive lipid PtdIns3P in various biological samples
    Gaëtan Chicanne
    INSERM, U1048 and Université Toulouse 3, I2MC, Avenue Jean Poulhès BP84225, 31432 Toulouse cedex 04, France
    Biochem J 447:17-23. 2012
    ..Using this assay, we show an increase in the mass level of PtdIns3P in mouse and human platelets following stimulation, loss of this lipid in Vps34-deficient yeasts and its relative enrichment in early endosomes isolated from BHK cells...
  2. doi request reprint Phosphoinositides and cellular pathogens
    Bernard Payrastre
    INSERM, U1048, Université Toulouse 3, I2MC, Hôpital de Toulouse, BP 84225 Avenue Jean Poulhès, 31432, Toulouse cedex 04, France
    Subcell Biochem 59:363-88. 2012
    ....
  3. doi request reprint Regulation and roles of PI3Kβ, a major actor in platelet signaling and functions
    Marie Pierre Gratacap
    INSERM, U563, Universite Toulouse III, Centre de Physiopathologie de Toulouse Purpan, CHU Purpan, Toulouse, France
    Adv Enzyme Regul 51:106-16. 2011
    ..The present review summarizes recent data concerning the mechanisms of PI3Kβ regulation and the roles of this PI3K isoform in blood platelet functions and other cell types...
  4. doi request reprint Shigella flexneri infection generates the lipid PI5P to alter endocytosis and prevent termination of EGFR signaling
    Damien Ramel
    INSERM, U1048, Université Toulouse 3, I2MC and Hôpital de Toulouse, Avenue Jean Poulhès BP84225, 31432 Toulouse cedex 04, France
    Sci Signal 4:ra61. 2011
    ..flexneri to favor survival of host cells...
  5. doi request reprint Chronic estradiol treatment reduces platelet responses and protects mice from thromboembolism through the hematopoietic estrogen receptor α
    Marie Cecile Valera
    INSERM, U1048 and Université Toulouse 3, I2MC, Toulouse, France
    Blood 120:1703-12. 2012
    ..Overall, these data demonstrate a previously unrecognized role for E2 in regulating the platelet proteome and platelet function, and point to new potential antithrombotic and vasculoprotective therapeutic strategies...
  6. ncbi request reprint Phosphatidylinositol 5-phosphate regulates invasion through binding and activation of Tiam1
    Julien Viaud
    INSERM, UMR1048, Universite Toulouse III, Institut des Maladies Métaboliques et Cardiovasculaires, 31432 Toulouse, France
    Nat Commun 5:4080. 2014
    ..The discovery that PtdIns5P could be a keystone of GTPases and cytoskeleton spatiotemporal regulation opens important research avenues towards unravelling new strategies counteracting cell invasion. ..
  7. doi request reprint Deletion of the p110beta isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo
    Valerie Martin
    INSERM, U563, Centre de Physiopathologie de Toulouse Purpan, Département d Oncogenèse, Signalisation et Innovation thérapeutique, and Université Toulouse III Paul Sabatier, Toulouse, France
    Blood 115:2008-13. 2010
    ....
  8. doi request reprint Inherited platelet disorders and oral health
    Marie Cecile Valera
    INSERM, U1048, Université Toulouse 3, I2MC, Equipe 11, CHU Rangueil, Toulouse, France
    J Oral Pathol Med 42:115-24. 2013
    ..In this review, we will discuss the management of patients with inherited platelet disorders in various clinical situations related to dental cares, including surgical intervention...
  9. doi request reprint Regulation of the DH-PH tandem of guanine nucleotide exchange factor for Rho GTPases by phosphoinositides
    Julien Viaud
    INSERM, UMR1048, Universite Paul Sabatier, Institut des Maladies Métaboliques et Cardiovasculaires, I2MC, 1 avenue Jean Poulhes, BP 84225, 31432 Toulouse Cedex 4, France
    Adv Biol Regul 52:303-14. 2012
    ..This review summarizes data on the regulation of RhoGEFs activity through interaction of the PH-associated DH domain with phosphoinositides which are considered as critical players in the spatial organization of major signaling pathways...
  10. pmc The nucleophosmin-anaplastic lymphoma kinase oncogene interacts, activates, and uses the kinase PIKfyve to increase invasiveness
    Sophie Dupuis-Coronas
    INSERM, U1048, I2MC, Universite Toulouse III Paul Sabatier, Centre Hospitalier Universitaire de Toulouse, Toulouse Cedex 4, France
    J Biol Chem 286:32105-14. 2011
    ..Accordingly, immunofluorescence studies confirm a perturbation of matrix metalloproteinase 9 localization at the cell surface and defect in maturation. Altogether, these results suggest a role for PIKfyve in NPM-ALK-mediated invasion...
  11. doi request reprint Class I phosphoinositide 3-kinases in normal and pathologic hematopoietic cells
    François Vergez
    Cancer Research Center of Toulouse and Laboratoire d Hématologie, Hôpital de Toulouse, France
    Curr Top Microbiol Immunol 362:163-84. 2012
    ....