Patrizia Paterlini-Brechot

Summary

Country: France

Publications

  1. ncbi Circulating tumor cells (CTC) detection: clinical impact and future directions
    Patrizia Paterlini-Brechot
    INSERM, Unité 807, Paris, F 75730 France
    Cancer Lett 253:180-204. 2007
  2. ncbi Hepatitis B virus-related insertional mutagenesis occurs frequently in human liver cancers and recurrently targets human telomerase gene
    Patrizia Paterlini-Brechot
    INSERM Pasteur Unit 370, Necker Faculty of Medicine, Necker Enfants Malades Hospital, Paris 75015, France
    Oncogene 22:3911-6. 2003
  3. pmc SERCA1 truncated proteins unable to pump calcium reduce the endoplasmic reticulum calcium concentration and induce apoptosis
    M Chami
    The French Institute of Health and Medical Research Institut National de la Santé et de la Recherche Médicale INSERM Pasteur U370 Necker Faculty Institute of Medicine, 75015 Paris, France
    J Cell Biol 153:1301-14. 2001
  4. ncbi Circulating tumorous cells in patients with hepatocellular carcinoma. Clinical impact and future directions
    P Paterlini-Brechot
    Unité INSERM 370, Institut Necker Pasteur, Paris, France
    Semin Cancer Biol 10:241-9. 2000
  5. ncbi [Non invasive prenatal diagnosis of trisomy 21: dream or reality?]
    Patrizia Paterlini-Brechot
    Inserm U807, Faculte de Medecine Necker Enfants Malades, Universite Paris V, 156, rue de Vaugirard, 75015 Paris, France
    Med Sci (Paris) 23:592-4. 2007
  6. ncbi [Impact of calcium signaling in liver carcinogenesis]
    Mounia Chami
    Inserm U807, Faculte de Medecine Necker Enfants Malades, Universite Paris V, 156, rue de Vaugirard, 75015 Paris, France
    Med Sci (Paris) 23:133-5. 2007
  7. pmc Enrichment, immunomorphological, and genetic characterization of fetal cells circulating in maternal blood
    Giovanna Vona
    Unité INSERM 370, Faculte de Medecine Necker, Paris, France
    Am J Pathol 160:51-8. 2002
  8. pmc Identification and functional characterization of a new member of the human Mcm protein family: hMcm8
    Devrim Gozuacik
    INSERM Unit 370 Pasteur Institute, Faculte de Medecine Necker Enfants Malades, 156 rue de Vaugirard, 75730, Paris, France
    Nucleic Acids Res 31:570-9. 2003
  9. doi Circulating trophoblastic cells provide genetic diagnosis in 63 fetuses at risk for cystic fibrosis or spinal muscular atrophy
    Hussein Mouawia
    Unité INSERM 807, Universite Paris Descartes, Paris, France
    Reprod Biomed Online 25:508-20. 2012
  10. ncbi Impact of cytomorphological detection of circulating tumor cells in patients with liver cancer
    Giovanna Vona
    Pasteur INSERM Unit 370, Faculte de Medecine Necker Enfants Malades, 156 rue de Vaugirard, 75739 Paris cedex 15, France
    Hepatology 39:792-7. 2004

Collaborators

Detail Information

Publications13

  1. ncbi Circulating tumor cells (CTC) detection: clinical impact and future directions
    Patrizia Paterlini-Brechot
    INSERM, Unité 807, Paris, F 75730 France
    Cancer Lett 253:180-204. 2007
    ..The interest in development and assessment of this noninvasive marker should lead to more effective and better tailored anticancer treatments for individual patients, thus resulting in their improved life expectancy...
  2. ncbi Hepatitis B virus-related insertional mutagenesis occurs frequently in human liver cancers and recurrently targets human telomerase gene
    Patrizia Paterlini-Brechot
    INSERM Pasteur Unit 370, Necker Faculty of Medicine, Necker Enfants Malades Hospital, Paris 75015, France
    Oncogene 22:3911-6. 2003
    ..Thus, HBV frequently targets cellular genes involved in cell signalling and some of them may be preferential targets of the viral integration...
  3. pmc SERCA1 truncated proteins unable to pump calcium reduce the endoplasmic reticulum calcium concentration and induce apoptosis
    M Chami
    The French Institute of Health and Medical Research Institut National de la Santé et de la Recherche Médicale INSERM Pasteur U370 Necker Faculty Institute of Medicine, 75015 Paris, France
    J Cell Biol 153:1301-14. 2001
    ..These data reveal a further mechanism modulating Ca(2+) accumulation into the ER of nonmuscle cells and highlight the relevance of S1T proteins to the control of apoptosis...
  4. ncbi Circulating tumorous cells in patients with hepatocellular carcinoma. Clinical impact and future directions
    P Paterlini-Brechot
    Unité INSERM 370, Institut Necker Pasteur, Paris, France
    Semin Cancer Biol 10:241-9. 2000
    ..They allow immunomorphological and molecular characterization of individual tumor cells. Based on these new results, new therapeutic approaches of metastases should be developed in the near future...
  5. ncbi [Non invasive prenatal diagnosis of trisomy 21: dream or reality?]
    Patrizia Paterlini-Brechot
    Inserm U807, Faculte de Medecine Necker Enfants Malades, Universite Paris V, 156, rue de Vaugirard, 75015 Paris, France
    Med Sci (Paris) 23:592-4. 2007
  6. ncbi [Impact of calcium signaling in liver carcinogenesis]
    Mounia Chami
    Inserm U807, Faculte de Medecine Necker Enfants Malades, Universite Paris V, 156, rue de Vaugirard, 75015 Paris, France
    Med Sci (Paris) 23:133-5. 2007
  7. pmc Enrichment, immunomorphological, and genetic characterization of fetal cells circulating in maternal blood
    Giovanna Vona
    Unité INSERM 370, Faculte de Medecine Necker, Paris, France
    Am J Pathol 160:51-8. 2002
    ..We conclude that this is a powerful approach to enrich circulating fetal cells and prove their fetal origin, and that it may have implications for noninvasive prenatal diagnosis of genetic disorders...
  8. pmc Identification and functional characterization of a new member of the human Mcm protein family: hMcm8
    Devrim Gozuacik
    INSERM Unit 370 Pasteur Institute, Faculte de Medecine Necker Enfants Malades, 156 rue de Vaugirard, 75730, Paris, France
    Nucleic Acids Res 31:570-9. 2003
    ..Overall, our data identify a new Mcm protein, which does not form part of the Mcm2-7 complex and which is only structure-bound during S phase, thus suggesting its specific role in DNA replication...
  9. doi Circulating trophoblastic cells provide genetic diagnosis in 63 fetuses at risk for cystic fibrosis or spinal muscular atrophy
    Hussein Mouawia
    Unité INSERM 807, Universite Paris Descartes, Paris, France
    Reprod Biomed Online 25:508-20. 2012
    ..CFTC were found to circulate from 5 weeks of gestation and can be used to develop an early and reliable approach for NI-PND...
  10. ncbi Impact of cytomorphological detection of circulating tumor cells in patients with liver cancer
    Giovanna Vona
    Pasteur INSERM Unit 370, Faculte de Medecine Necker Enfants Malades, 156 rue de Vaugirard, 75739 Paris cedex 15, France
    Hepatology 39:792-7. 2004
    ..We also show the feasibility of molecular studies of individual circulating tumor cells, aimed at identifying gene mutations involved in tumor invasion...
  11. ncbi Cytobiological consequences of calcium-signaling alterations induced by human viral proteins
    Mounia Chami
    Inserm U807, F 75015 Paris, France
    Biochim Biophys Acta 1763:1344-62. 2006
    ..These data point out calcium-signaling as a key cellular target for viral infection and should stimulate further studies exploring new calcium-related therapeutic strategies...
  12. pmc Identification of CANT1 mutations in Desbuquois dysplasia
    Celine Huber
    Paris Descartes University, Department of Genetics and INSERM U781 and U807, Hopital Necker Enfants Malades, 75015 Paris, France
    Am J Hum Genet 85:706-10. 2009
    ..We also found electron-dense material within distended rough endoplasmic reticulum in the fibroblasts of Desbuquois patients. Our findings demonstrate the specific involvement of a nucleotidase in the endochondral ossification process...
  13. ncbi Genetic characterisation of circulating fetal cells allows non-invasive prenatal diagnosis of cystic fibrosis
    Ali Saker
    INSERM, Unité 807, Paris, France, Universite Rene Descartes, Paris, France
    Prenat Diagn 26:906-16. 2006
    ..The purpose of this study was to develop a molecular method to characterise both paternal and maternal CFTR alleles in DNA from circulating fetal cells (CFCs) isolated by ISET (isolation by size of epithelial tumour/trophoblastic cells)...