Research Topics
| Nathalie ParezSummaryCountry: France Publications
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Detail Information
Publications
Rotavirus gastroenteritis: why to back up the development of new vaccines?Nathalie Parez
Urgences Pédiatriques, Hopital Trousseau, AP HP, Universite Pierre et Marie Curie, EA3500, 26 rue du Dr A Netter, 75571 Paris Cedex 12, France
Comp Immunol Microbiol Infect Dis 31:253-69. 2008..The answer brought by the development of new RV vaccines could reside in developing several types of RV vaccines specifically designed to be used in different settings...
Rectal immunization with rotavirus virus-like particles induces systemic and mucosal humoral immune responses and protects mice against rotavirus infectionNathalie Parez
Service des Urgences Médicales Pédiatriques, Hopital Armand Trousseau, 26 Ave du Dr Arnold Netter, 75571 Paris Cedex 12, France
J Virol 80:1752-61. 2006..Rectal delivery of a VLP-based vaccine might allow the use of adjuvants less toxic than, but as efficient as, CT...
[From structural and antigenic features of the rotavirus to the development of the vaccines]N Parez
Service des urgences pédiatriques, Hôpital d enfants A Trousseau, APHP, 26 rue du Dr Netter, 75571 Paris Cedex 12, France
Arch Pediatr 14:S186-93. 2007..The development of these two vaccines has followed two different strategies. Despite their differences, these vaccines are both safe and efficient in protecting young infants against severe rotavirus acute gastroenteritis...
[Frequency and clinical characteristics of rotavirus acute gastroenteritis in children under 5 years of age treated in community practice in France]N Parez
Urgences Pédiatriques, Hopital Armand Trousseau, APHP, 26, rue du Docteur A Netter, 75571 Paris Cedex 12, France
Pathol Biol (Paris) 55:453-9. 2007..A secondary objective was to compare the clinical characteristics of children with and without rotavirus acute gastro-enteritis (RV AGE)...
The VP6 protein of rotavirus interacts with a large fraction of human naive B cells via surface immunoglobulinsNathalie Parez
Service des Urgences Médicales Pédiatriques, Hopital Armand Trousseau, 26 Ave du Dr Arnold Netter, 75571 Paris Cedex 12, France
J Virol 78:12489-96. 2004..We propose that naive B cell-VP6 interaction might influence the strength and quality of the acquired immune response and should be considered for elaborating RV vaccine strategies...
Papular-purpuric gloves and socks syndrome associated with B19V infection in a 6-year-old childNathalie Parez
AP HP, Hopital d Enfants Armand Trousseau, Urgences Pédiatriques, 26 rue du Dr A Netter, 75571 Paris, France
J Clin Virol 44:167-9. 2009..The distinctive clinical characteristics of PPGSS in children should be recognized by paediatrician in particular at the emergency room in order to avoid superfluous explorations...
Rearrangements of rotavirus genomic segment 11 are generated during acute infection of immunocompetent children and do not occur at randomNathalie Schnepf
Laboratoire de Virologie, Hopital Armand Trousseau, 26 avenue du Dr Arnold Netter, 75571 Paris Cedex 12, France
J Virol 82:3689-96. 2008..We show that under such conditions of infection, the viral RNA polymerase generates rearrangements which occur not at random but within direct repeats which might constitute hot spots for RNA recombination...
[Osteoarticular infections: therapeutic proposals of the Paediatric Infectious Diseases Group of the French Society of Paediatrics (GPIP)]E Grimprel
Groupe de pathologie infectieuse pédiatrique de la Société française de pédiatrie, Hopital Armand Trousseau, 26 av Dr Arnold Netter 75012 Paris, Universite Pierre et Marie Curie Paris VI, France
Arch Pediatr 15:S74-80. 2008....
[Osteoarticular infections: clinical studies]E Grimprel
Groupe de pathologie infectieuse pédiatrique de la Société française de pédiatrie, Hopital Armand Trousseau, 26 av Dr Arnold Netter 75012 Paris, Universite Pierre et Marie Curie Paris VI, France
Arch Pediatr 15:S68-73. 2008..The aim of this article is to review the evolution of therapeutic concepts of treatment of bone and joint infections in paediatrics for 40 years with the aid of main published clinical studies...
[Acute diarrhea and rotavirus infection in the child: assessment of data from emergency care and and the microbiology laboratory of the Armand-Trousseau (Paris) Hospital between 1988 and 2001]E Grimprel
Service de Pediatrie, Urgences, pathologie infectieuse et tropicale, Hopital Armand Trousseau, 26, avenue du Docteur Arnold Netter, 75012 Paris, France
Arch Pediatr 8:1318-24. 2001..Following data were simultaneously collected: consultations and hospitalizations for acute diarrhea at the emergency room, and identifications of rotavirus from diarrheic stools at the laboratory...
[Management of intussusception in France in 2004: investigation of the Paediatric Infectious Diseases Group, the French Group of Paediatric Emergency and Reanimation, and the French Society of Paediatric Surgery]E Grimprel
Service de Pediatrie, Hopital Armand Trousseau, 26, avenue du Docteur Arnold Netter, 75012 Paris, France
Arch Pediatr 13:1581-8. 2006..To describe the different pathways of management of intussusception (IS) in infants and children in metropolitan France and to identify paediatric emergency centres that might constitute a surveillance network for IS...
[Causes of hospitalization of patients with ongoing varicella in a French children hospital: evolution between 1990 and 2001]A Mandelcwajg
APHP, Hopital d Enfants Armand Trousseau, Consultation, Urgences, pathologie infectieuse et tropicale, 26, avenue du Docteur Arnold Netter, 75012 Paris, France
Arch Pediatr 13:429-35. 2006..To describe the characteristics of paediatric varicella in patients admitted through the emergency department (ED) of the Armand-Trousseau Children hospital in Paris and the evolution of the causes of admission during the study period...
[Benign afebrile seizures in rotavirus gastroenteritis]G Patteau
Service des urgences pédiatriques, Hopital Necker Enfants Malades, AP HP, Universite Paris 5, 149, rue de Sevres, 75743 Paris Cedex 15, France
Arch Pediatr 17:1527-30. 2010..As rotavirus is the most common agent among the diarrheal viruses detected to be the cause of CwG, one could hypothesize that this virus may play a role in the CwG pathogenesis...
Recombinant rotavirus inner core proteins produced in the milk of transgenic rabbits confer a high level of protection after intrarectal deliveryEric Soler
Biologie du Développement et de la Reproduction, Domaine de Vilvert, 78352 Jouy en Josas Cedex, France
Vaccine 25:6373-80. 2007..We thus demonstrate in clinically feasible settings that mass production of viral protein in transgenic milk is a promising way to generate subunit vaccine against rotavirus...
Rotavirus vaccines: considerations for successful implementation in EuropePierre Van Damme
Centre for the Evaluation of Vaccination, University of Antwerp, Belgium
Lancet Infect Dis 6:805-12. 2006..Further studies on the cost of the disease and the benefit of vaccination, together with raising awareness are necessary steps to ensure successful implementation of rotavirus vaccination in Europe...
Rotavirus anti-VP6 secretory immunoglobulin A contributes to protection via intracellular neutralization but not via immune exclusionBlaise Corthesy
R and D Laboratory of the Division of Immunology and Allergy, DMI CHUV, Rue du Bugnon, 1011 Lausanne, Switzerland
J Virol 80:10692-9. 2006..These findings identify a mechanism whereby the well-conserved immunodominant VP6 protein can function as a target for heterotypic antibodies and protective immunity...
