Research Topics
| Hilario NunesSummaryCountry: France Publications
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Publications
SarcoidosisHilario Nunes
Service de Pneumologie, Hopital Avicenne, Assistance Publique Hôpitaux de Paris et Faculté de Médecine, Universite Paris Nord, 93009 Bobigny, France
Orphanet J Rare Dis 2:46. 2007..In some strictly selected cases refractory to standard therapy, specific antiTNF-alpha agents may offer precious improvement. Some patients benefit from topical corticosteroids...
[Sarcoidosis treatment]Hilario Nunes
Service de Pneumologie, Hôpital Avicenne AP HP, Université Paris Nord 13, 93009 Bobigny Cedex, France
Rev Prat 58:1099-104. 2008..Although other drugs are only occasionnally needed, the available therapeutical range is wide (thalidomide, infliximab, cyclophosphamide, leflunomide...)...
Cardiac sarcoidosisHilario Nunes
Service de Pneumologie, Hopital Avicenne, Assistance Publique Hopitaux de Paris, Bobigny, France
Semin Respir Crit Care Med 31:428-41. 2010..Cardiac transplantation is exceptionally required...
Pulmonary hypertension complicating sarcoidosisHilario Nunes
University Paris 13, UPRES EA 2363, Assistance Publique Hopitaux de Paris, Avicenne Hospital, Department of Pneumology, 93009 Bobigny, France
Presse Med 41:e303-16. 2012..Data on the efficacy and safety of PAH agents are scarce and discrepant. Further controlled trials are warranted and should integrate the concept of disproportionate PH in their design...
Imaging of sarcoidosis of the airways and lung parenchyma and correlation with lung functionHilario Nunes
Department of Pneumology, University of Paris 13, UPRES EA 2363, Assistance Publique Hopitaux de Paris, Avicenne Hospital, Bobigny, France
Eur Respir J 40:750-65. 2012....
[Thoracic sarcoidosis]Hilario Nunes
Universite Paris 13, EA2363, AP HP, Hopital Avicenne, Service de Pneumologie, F 93000 Bobigny, France
Presse Med 39:93-106. 2010..Systemic corticosteroid therapy remains the reference treatment for thoracic involvement in sarcoidosis...
Stage IV sarcoidosis: comparison of survival with the general population and causes of deathA Nardi
Dept of Pneumology, Avicenne Hospital, University Paris 13, UPRES EA 2363, Assistance Publique Hopitaux de Paris, Bobigny, France
Eur Respir J 38:1368-73. 2011..Survival is significantly decreased in stage IV patients. 75% of fatalities are directly attributable to respiratory causes...
Imaging in sarcoidosisHilario Nunes
Services de Pneumologie, Hôpital Universitaire Avicenne, Bobigny, France
Semin Respir Crit Care Med 28:102-20. 2007..We review the salient features and role of magnetic resonance imaging and diverse radionuclide techniques to diagnose or follow selected cases of extrapulmonary sarcoidosis...
Acute exacerbation of idiopathic pulmonary fibrosis: outcome and prognostic factorsVirginie Simon-Blancal
Service de Pneumologie, Hôpital Universitaire Avicenne, Assistance Publique Hopitaux de Paris, Bobigny, France
Respiration 83:28-35. 2012..Acute exacerbation is a substantial cause of death in patients with idiopathic pulmonary fibrosis with poorly described prognostic factors...
Progression of idiopathic pulmonary fibrosis: lessons from asymmetrical diseaseColas Tcherakian
Service de Pneumologie, Universite Paris 13, UPRES EA 2363, Assistance Publique Hopitaux de Paris, Hopital Avicenne, Bobigny, France
Thorax 66:226-31. 2011..From this perspective, patients with asymmetrical disease (AIPF) may be unique...
High-resolution computed tomographic imaging of airways in sarcoidosis patients with airflow obstructionJean Marc Naccache
Universite Paris 13, Service de Pneumologie, Hopital Avicenne, Bobigny Cedex, France
J Comput Assist Tomogr 32:905-12. 2008..To investigate airway involvement in patients with pulmonary sarcoidosis and airflow obstruction (AO) using high-resolution computed tomography...
Pulmonary cavitary sarcoidosis: clinico-radiologic characteristics and natural history of a rare form of sarcoidosisSandrine Hours
Services de Pneumologie, AP HP Hôpital Universitaire Avicenne, Bobigny, France
Medicine (Baltimore) 87:142-51. 2008..In summary, cavitary lesions are rare in pulmonary sarcoidosis and usually occur in active and severe sarcoidosis. Their evolution is unpredictable, and complications are frequent...
High-resolution computed tomography to differentiate chronic diffuse interstitial lung diseases with predominant ground-glass pattern using logical analysis of dataSophie Grivaud Martin
UPRES EA 2363, Department of Radiology, Universite Paris 13, Assistance Publique Hopitaux de Paris, Hopital Avicenne, 125 route de Stalingrad, 93000 Bobigny, France
Eur Radiol 20:1297-310. 2010..We evaluated the performance of high-resolution computed tomography (HRCT) to differentiate chronic diffuse interstitial lung diseases (CDILD) with predominant ground-glass pattern by using logical analysis of data (LAD)...
[Natural history of sarcoidosis]Dominique Valeyre
Service de Pneumologie, Hôpital Avicenne AP HP, Université Paris Nord 13, 93009 Bobigny Cedex, France
Rev Prat 58:1091-4. 2008..An accurate knowledge of the natural history allows enhance the security of diagnosis, to plan the survey and to better interpret clinical events during evolution...
[Sarcoidosis: the involvement of anterior pituitary hormones is poorly recognized]Hélène Bihan
Hopital Avicenne, Service d endocrinologie, diabétologie et maladies métaboliques, 93009 Bobigny, France
Presse Med 41:e524-9. 2012..The objective of this study was to evaluate the impact on the detection of hypothalamic-pituitary sarcoidosis in patients hospitalized for this condition in a lung disease sensibilized department...
[Combined pulmonary fibrosis and emphysema]Vincent Cottin
Service de Pneumologie, centre de référence des maladies orphelines pulmonaires, Hopital Louis Pradel, Lyon, France
Presse Med 36:936-44. 2007..Pulmonary hypertension is present in almost half of all patients and represents the principal negative prognostic factor for this condition, which has a median survival of 6 years...
Endoluminal stenosis of proximal bronchi in sarcoidosis: bronchoscopy, function, and evolutionArnaud Chambellan
Service de Pneumologie, Centre Hospitalo Universitaire Avicenne, 125 route de Stalingrad, 93009 Bobigny Cedex, France
Chest 127:472-81. 2005..Endoluminal stenosis of proximal bronchi (ESPB) is a potentially severe manifestation of sarcoidosis. Unusual clinical presentation and variable response to medical treatment require specific attention to diagnosis and follow-up...
Membrane and capillary blood components of diffusion capacity of the lung for carbon monoxide in pulmonary sarcoidosis: relation to exercise gas exchangeChristine Lamberto
Department of Physiology, Assistance Publique Hopitaux de Paris, Hopital Avicenne, Bobigny, France
Chest 125:2061-8. 2004..However, the relative contribution of each of the two components of DLCO-alveolar membrane diffusing capacity (Dm) and pulmonary capillary blood volume (Vc)-remains unclear...
CT findings in severe thoracic sarcoidosisAnne-Sophie Hennebicque
Department of Radiology, , UFR Bobigny, , 125, route de Stalingrad, 93009 Bobigny, France
Eur Radiol 15:23-30. 2005....
Sinonasal involvement in sarcoidosis: a case-control study of 20 patientsFleur Cohen Aubart
, UPRES EA 2363, Services de Pneumologie, , , Bobigny, France
Medicine (Baltimore) 85:365-71. 2006..0001). Corticosteroids maintenance dosage was high (10.5 +/- 6 mg daily) and mainly depended on SN involvement. Although rare, SN involvement is a severe and recalcitrant manifestation of sarcoidosis representing a therapeutic challenge...
[Diagnostic challenges in sarcoidosis]Diane Bouvry
Service de Pneumologie, Hopital Avicenne, AP HP, Université Paris Nord 13, 93009 Bobigny Cedex, France
Rev Prat 58:1095-7. 2008..Lastly, clinical course manifestations rise to know the discriminate between sarcoidosis, treatment side-effects and others sarcoidosis-associated diseases...
[Benefits of imaging in therapeutic management of sarcoidosis]Michel Brauner
Service de Radiologie, , EA 2363, , 93009 Bobigny Cedex, France
Rev Prat 58:1081-90. 2008
Clinical value of a high-fat and low-carbohydrate diet before FDG-PET/CT for evaluation of patients with suspected cardiac sarcoidosisMichael Soussan
Department of Nuclear Medicine, Faculte de Medecine, University Paris 13, Sorbonne Paris Cité, Bobigny, France
J Nucl Cardiol 20:120-7. 2013..We hypothesized that a high-fat and low-carbohydrate (HFLC) diet before FDG-PET/CT could identify patients with active cardiac sarcoidosis (CS)...
[Innovative therapeutics for idiopathic pulmonary fibrosis]Yurdagul Uzunhan
Universite Paris 13, PRES Sorbonne Paris Cité, EA 2363, Assistance Publique Hopitaux de Paris, Hopital Avicenne, Service de Pneumologie, 93000 Bobigny, France
Presse Med 40:1100-12. 2011..Many novel and promising drugs based on recent targets are under investigation. Combined therapies targeting different pathogenic pathways may represent the future for the treatment of IPF...
[Epidemiology of interstitial lung diseases]Dominique Valeyre
Université Paris Nord 13, EA2363, F 93017 Bobigny Cedex, France
Presse Med 39:53-9. 2010....
Granulomatosis-associated common variable immunodeficiency disorder: a case-control study versus sarcoidosisDiane Bouvry
please see the Acknowledgements section
Eur Respir J 41:115-22. 2013..ILD in CVID/GD presents a specific clinical picture and evolution that are markedly different from those of sarcoidosis...
Acute respiratory failure after interferon-gamma therapy of end-stage pulmonary fibrosisIsabelle Honoré
Service de Pneumologie, and Unité INSERM 408, Hopital Bichat, 46 rue Henri Huchard, 75877 Paris Cedex 18, France
Am J Respir Crit Care Med 167:953-7. 2003..These cases suggest that IFN-gamma therapy can induce an acute respiratory failure in patients with end-stage idiopathic pulmonary fibrosis...
Treatment of chronic pulmonary aspergillosis by voriconazole in nonimmunocompromised patientsJuliette Camuset
Department of Pneumology and Respiratory Intensive Care, Assistance Publique Hopitaux de Paris, Tenon Hospital, 4 rue de la Chine, 75970 Paris, France
Chest 131:1435-41. 2007..To evaluate the efficacy of voriconazole in this setting, we conducted a retrospective multicenter study over a 3-year period...
Clonality and phenotyping analysis of alveolar lymphocytes is suggestive of pulmonary MALT lymphomaRaphael Borie
Service de Pneumologie et Reanimation, Assistance Publique Hopitaux de Paris, France
Respir Med 105:1231-7. 2011..It often associates with connective tissue disease (CTD). We aimed to evaluate the impact of concomitant CTD on diagnostic value of flow cytometry and genetic clonality analyses for the diagnostic of MALT lymphoma...
[Management of hepato-pulmonary syndrome]Hilario Nunes
UPRES EA 2363, Service de Pneumologie, , , , 125, rue de Stalingrad, 93009 Bobigny
Gastroenterol Clin Biol 28:B156-68. 2004
