Research Topics
| Fati NourhashemiSummaryCountry: France Publications
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Publications
End-of-life care for persons with advanced Alzheimer disease: design and baseline data from the ALFINE studyF Nourhashemi
Gerontopole, CHU de Toulouse, 31300 France
J Nutr Health Aging 16:457-61. 2012..Alzheimer disease (AD) is the most common cause of dementia. Most affected individuals survive to an advanced stage of dementia, which is under-recognized as a terminal illness...
Effectiveness of a specific care plan in patients with Alzheimer's disease: cluster randomised trial (PLASA study)Fati Nourhashemi
Gerontopole, CMRR, Toulouse, France
BMJ 340:c2466. 2010..To test the effectiveness of a comprehensive specific care plan in decreasing the rate of functional decline in patients with mild to moderate Alzheimer's disease compared with usual care in memory clinics...
Predictive value of rapid decline in mini mental state examination in clinical practice for prognosis in Alzheimer's diseaseMaria E Soto
Department of Geriatric Medicine, Toulouse University Hospital, Toulouse, France
Dement Geriatr Cogn Disord 26:109-16. 2008..Given the poorer prognosis of Alzheimer's disease (AD) patients with rapid cognitive decline (RCD), there is a need for a clinical assessment tool to detect these patients...
Prognosis of an abnormal one-leg balance in community-dwelling patients with Alzheimer's disease: a 2-year prospective study in 686 patients of the REAL.FR studySandrine Sourdet
Internal Medicine Service and Gerontology Clinic, Hopital La Grave Casselardit, Toulouse, France
J Am Med Dir Assoc 13:407.e1-6. 2012..The aim of this study was to explore the predictive value of an abnormal one-leg balance (OLB) test for functional decline, nursing home admission, and mortality in community-dwelling patients affected with Alzheimer's disease (AD)...
Weight loss and rapid cognitive decline in community-dwelling patients with Alzheimer's diseaseMaria E Soto
Alzheimer s Disease Research and Clinical Centre, Department of Geriatric Medicine, Gerontopole, Toulouse University Hospital, Toulouse, France
J Alzheimers Dis 28:647-54. 2012..50, 95% CI = 1.04-2.17). In conclusion, weight loss predicted RCD in this cohort. Whether the prevention of weight loss (by improving nutritional status) impacts cognitive decline remains an open question...
A 2-year follow-up of 233 very mild (CDR 0.5) Alzheimer's disease patients (REAL.FR cohort)Fati Nourhashemi
CHU Toulouse, Hôpital Casselardit, Service de médecine interne et gérontologie clinique, Toulouse, France
Int J Geriatr Psychiatry 23:460-5. 2008..The primary objective of our study was to examine the evolution of AD in individuals with very mild AD (CDR 0.5) across a 2-year follow up...
Long-term progression of Alzheimer's disease in patients under antidementia drugsSophie Gillette-Guyonnet
Department of Internal Medicine and Geriatrics, Purpan University Hospital, Gerontopole Toulouse University Hospital, France
Alzheimers Dement 7:579-92. 2011..Data regarding the long-term disease progression outside of therapeutic trials are lacking. We examined the effects of standard of care for AD patients on the prognosis of the disease in a real-life study over a 4-year period...
An abnormal "one-leg balance" test predicts cognitive decline during Alzheimer's diseaseYves Rolland
INSERM, U558, Toulouse, France
J Alzheimers Dis 16:525-31. 2009..8 (0.3) points at two years (p < 0.001). An abnormal one-leg balance test is a marker of more advanced dementia and predicts a higher rate of cognitive decline...
Improving care of older adults with dementia: description of 6299 hospitalizations over 11 years in a special acute care unitMaria E Soto
Department of Geriatric Medicine, Gérontopôle de Toulouse, Toulouse University Hospital, Toulouse, France
J Am Med Dir Assoc 13:486.e1-6. 2012..To describe hospitalizations in a Special Acute Care inpatient Unit for older adults with Alzheimer's disease (AD) and other related disorders...
Prognosis of Alzheimer's disease today: a two-year prospective study in 686 patients from the REAL-FR StudyFrederic Cortes
Department of Internal Medicine and Clinical Gerontology, Centre Hospitalier Universitaire Purpan Casselardit, Toulouse, France
Alzheimers Dement 4:22-9. 2008..The aim of the present study was to describe the long-term evolution of Alzheimer's disease (AD) in a prospective cohort of patients under treatment with a close follow-up...
Wandering behavior and Alzheimer disease. The REAL.FR prospective studyYves Rolland
Service de Medecine Interne et de Gerontologie Clinique, Pavillon Junot, Hopital La Grave Casselardit, 170 avenue de Casselardit, Toulouse, France
Alzheimer Dis Assoc Disord 21:31-8. 2007..Risk for undernutrition and death are not increased in wanderers. Their higher risk of ADL disabilities and institutionalization are partly explained by their baseline characteristics...
Predictive factors of attrition in a cohort of Alzheimer disease patients. The REAL.FR studyNicola Coley
INSERM, U558, University of Toulouse III, Toulouse, France
Neuroepidemiology 31:69-79. 2008..Attrition, i.e. patient dropout, can threaten the validity of results in longitudinal studies. The aim of this study was to identify patient and caregiver factors predictive of attrition in a cohort of Alzheimer disease (AD) patients...
Special acute care unit for older adults with Alzheimer's diseaseMaria E Soto
CHU Toulouse, Department of Geriatric Medicine, Toulouse, France
Int J Geriatr Psychiatry 23:215-9. 2008..To describe the cognitive, functional, and nutritional features of patients admitted to a Special Acute Care Unit (SACU) for elderly patients with Alzheimer's disease (AD)...
Risk factors for functional decline and institutionalisation among community-dwelling older adults with mild to severe Alzheimer's disease: one year of follow-upMaria E Soto
, CHU Purpan-Casselardit, Toulouse, , France
Age Ageing 35:308-10. 2006
Cardiovascular disease risk factors and progression of Alzheimer's diseaseGabor Abellan van Kan
INSERM U558, Department of Geriatric Medicine, CHU Toulouse, Toulouse, France
Dement Geriatr Cogn Disord 27:240-6. 2009..To assess if cardiovascular disease risk factors (CVDRF) are predictive factors for poorer evolution of Alzheimer's disease (AD) patients in terms of cognitive decline...
Antidepressant use in Alzheimer's disease patients: results of the REAL.FR cohortChristophe Arbus
Paul Sabatier University, Department of Psychiatry and Medical Psychology, Purpan Casselardit Hospital, Toulouse, France
Int Psychogeriatr 22:120-8. 2010..The aim of this survey was to assess the prevalence of antidepressant use in AD and to identify the clinical factors associated with antidepressant prescription...
Association of Alzheimer's disease onset with ginkgo biloba and other symptomatic cognitive treatments in a population of women aged 75 years and older from the EPIDOS studySandrine Andrieu
Department of Internal Medicine and Clinical Gerontology, Acute Unit for Alzheimer s Patients, Toulouse, France
J Gerontol A Biol Sci Med Sci 58:372-7. 2003..The potential association between use of C4A treatments, in particular EGb 761 (standardized Ginkgo biloba extracts), and dementia of the Alzheimer type was investigated...
Cognitive function and caregiver burden: predictive factors for eating behaviour disorders in Alzheimer's diseaseStéphanie Rivière
Department of Internal Medicine and Clinical Gerontology, Hopital La Grave Casselardit, Toulouse, France
Int J Geriatr Psychiatry 17:950-5. 2002..These behaviours lead to weight loss and frequently to physicians using tube feeding. Little is known about factors correlated with feeding difficulties during AD...
Is there a relationship between fat-free soft tissue mass and low cognitive function? Results from a study of 7,105 womenFati Nourhashemi
Department of Internal Medicine and Gerontology Clinic, CHU Purpan Casselardit, Toulouse, France
J Am Geriatr Soc 50:1796-801. 2002..To test the hypothesis that low fat-free soft tissue mass and cognitive impairment are independently associated...
Nutritional status is associated with disease progression in very mild Alzheimer diseasePierre Jean Ousset
Department of Internal Medicine and Gerontology, Alzheimer Disease Center, CHU Purpan Casselardit, Toulouse, France
Alzheimer Dis Assoc Disord 22:66-71. 2008..Nutritional assessment should therefore form part of clinical evaluation of patients with AD at an early stage of the disease...
Family history of dementia does not influence the progression of Alzheimer's disease at two years: results from the REAL.FR StudyFrederic Cortes
Service de médecine interne et gérontologie clinique, Toulouse, France
Am J Alzheimers Dis Other Demen 21:131-6. 2006....
Patterns of dementia treatment use in assisted living facilities: a cross-sectional study of 1975 demented residentsNadège Barro-Belaygues
Gérontopôle de Toulouse, Department of Geriatric Medicine, Toulouse University Hospital, Toulouse, France
J Am Med Dir Assoc 12:648-54. 2011..To report the associated factors with the nonuse of cholinesterase-inhibitors and memantine in residents from assisted living (AL) facilities suffering from dementia...
Sarcopenia, calf circumference, and physical function of elderly women: a cross-sectional studyYves Rolland
Internal Medicine Service and Gerontology Clinic, Hopital La Grave Casselardit, Toulouse, France
J Am Geriatr Soc 51:1120-4. 2003..To determine whether calf circumference (CC), related to appendicular skeletal muscle mass, can be used as a measure of sarcopenia and is related to physical function...
[Specific care plan in different stages of Alzheimer's disease]Christophe Hein
Gerontopole, Service de médecine interne gériatrique, CHU de Toulouse, Hôpital Casselardit, 31300 Toulouse
Rev Prat 61:931-6. 2011..However, the practical aspects of the follow-up and the ways in which those can be improved are yet to be defined...
Predictive factors of acute hospitalization in 134 patients with Alzheimer's disease: a one year prospective studySandrine Andrieu
Department of Internal Medicine and Clinical Gerontology, Acute Unit for Alzheimer s Patients, Toulouse, France
Int J Geriatr Psychiatry 17:422-6. 2002..To evaluate the frequency of and determine predictive factors for acute hospitalization in a prospective study of patients with Alzheimer's disease (AD)...
