Nicaise T Ndam

Summary

Country: France

Publications

  1. ncbi Plasmodium falciparum population dynamics in a cohort of pregnant women in Senegal
    Juliette Guitard
    Institut de Recherche pour le Developpement, Universite Paris Descartes, France
    Malar J 9:165. 2010
  2. ncbi Plasmodium falciparum parasites causing cerebral malaria share variant surface antigens, but are they specific?
    Nabila Kheliouen
    Institut de Recherche pour le Développement IRD UMR216, Mother and Child faced with tropical infections Unit, Paris, 75006, France
    Malar J 9:220. 2010
  3. ncbi Differential evolution of anti-VAR2CSA- IgG3 in primigravidae and multigravidae pregnant women infected by Plasmodium falciparum
    Juliette Guitard
    Institut de recherche pour le developpement IRD, UR010, Mother and Child Health in the Tropics, Universite Paris Descartes, France
    Malar J 7:10. 2008
  4. ncbi Identification of glycosaminoglycan binding regions in the Plasmodium falciparum encoded placental sequestration ligand, VAR2CSA
    Mafalda Resende
    Centre for Medical Parasitology, Institute of International Health Immunology and Microbiology, University of Copenhagen, Department of Clinical Microbiology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
    Malar J 7:104. 2008
  5. ncbi Plasmodium falciparum transcriptome analysis reveals pregnancy malaria associated gene expression
    Nicaise Tuikue Ndam
    Institut de Recherche pour le Developpement, UR010 at Université Paris Descartes, Mother and Child Health in the Tropics, Faculte de Pharmacie, Paris, France
    PLoS ONE 3:e1855. 2008
  6. ncbi Towards a vaccine against pregnancy-associated malaria
    N Tuikue Ndam
    Institut de Recherche pour le Developpement, UR010, Laboratoire de Parasitologie, Universite Paris Descartes, IFR 71, 4, avenue de l Observatoire, 75006 Paris, France
    Parasite 15:515-21. 2008
  7. ncbi The NTS-DBL2X region of VAR2CSA induces cross-reactive antibodies that inhibit adhesion of several Plasmodium falciparum isolates to chondroitin sulfate A
    Pascal Bigey
    Unite de Pharmacologie Chimique et Genetique, Universite Paris Descartes, ENSCP Chimie ParisTech, CNRS UMR8151, INSERM U 1022, France
    J Infect Dis 204:1125-33. 2011

Collaborators

  • Ali Salanti
  • Thomas Lavstsen
  • Morten A Nielsen
  • Juliette Guitard
  • Philippe Deloron
  • Emmanuel Bischoff
  • Nicaise Tuikue Ndam
  • Pascal Bigey
  • Firmine Viwami
  • Nabila Kheliouen
  • N Tuikue Ndam
  • Mafalda Resende
  • Sedami Gnidehou
  • Justin Doritchamou
  • Daniel Scherman
  • Mickaël Quiviger
  • Aude Couturier
  • Agnes Aubouy
  • Nicaise Tuikue-Ndam
  • Christophe Rogier
  • Francis Lalya
  • Else C Eboumbou Moukoko
  • Jean Yves Coppee
  • Adam F Sander
  • Sisse B Ditlev
  • Caroline Proux
  • Madeleine Dahlbäck
  • Peter H David
  • Thor Theander
  • Alioune Gaye
  • Pernille Andersen
  • Thor G Theander

Detail Information

Publications7

  1. ncbi Plasmodium falciparum population dynamics in a cohort of pregnant women in Senegal
    Juliette Guitard
    Institut de Recherche pour le Developpement, Universite Paris Descartes, France
    Malar J 9:165. 2010
    ..VAR2CSA is the main candidate for a pregnancy malaria vaccine, but vaccine development may be complicated by its sequence polymorphism...
  2. ncbi Plasmodium falciparum parasites causing cerebral malaria share variant surface antigens, but are they specific?
    Nabila Kheliouen
    Institut de Recherche pour le Développement IRD UMR216, Mother and Child faced with tropical infections Unit, Paris, 75006, France
    Malar J 9:220. 2010
    ..This study investigated the antibody response specifically directed against VSA expressed by parasites isolated from individuals presenting a given type of clinical presentation...
  3. ncbi Differential evolution of anti-VAR2CSA- IgG3 in primigravidae and multigravidae pregnant women infected by Plasmodium falciparum
    Juliette Guitard
    Institut de recherche pour le developpement IRD, UR010, Mother and Child Health in the Tropics, Universite Paris Descartes, France
    Malar J 7:10. 2008
    ..Pregnant women develop protective anti-VSA IgG1 and IgG3 when infected by Plasmodium falciparum. The major target of IgG from serum of infected pregnant women is VAR2CSA...
  4. ncbi Identification of glycosaminoglycan binding regions in the Plasmodium falciparum encoded placental sequestration ligand, VAR2CSA
    Mafalda Resende
    Centre for Medical Parasitology, Institute of International Health Immunology and Microbiology, University of Copenhagen, Department of Clinical Microbiology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
    Malar J 7:104. 2008
    ..It is thus of high priority to define minimal ligand binding regions throughout the VAR2CSA molecule...
  5. ncbi Plasmodium falciparum transcriptome analysis reveals pregnancy malaria associated gene expression
    Nicaise Tuikue Ndam
    Institut de Recherche pour le Developpement, UR010 at Université Paris Descartes, Mother and Child Health in the Tropics, Faculte de Pharmacie, Paris, France
    PLoS ONE 3:e1855. 2008
    ..Recent advances on the molecular basis of virulence and immune evasion have helped identify var2csa as a PAM-specific var gene...
  6. ncbi Towards a vaccine against pregnancy-associated malaria
    N Tuikue Ndam
    Institut de Recherche pour le Developpement, UR010, Laboratoire de Parasitologie, Universite Paris Descartes, IFR 71, 4, avenue de l Observatoire, 75006 Paris, France
    Parasite 15:515-21. 2008
    ..However, despite particular structure and interclonal conservation of VAR2CSA among other PfEMP1, significant challenges still exist concerning the development of a VAR2CSA-based vaccine with profound efficacy...
  7. ncbi The NTS-DBL2X region of VAR2CSA induces cross-reactive antibodies that inhibit adhesion of several Plasmodium falciparum isolates to chondroitin sulfate A
    Pascal Bigey
    Unite de Pharmacologie Chimique et Genetique, Universite Paris Descartes, ENSCP Chimie ParisTech, CNRS UMR8151, INSERM U 1022, France
    J Infect Dis 204:1125-33. 2011
    ..Acquired anti-VAR2CSA antibodies have been associated with improved pregnancy outcomes, suggesting a vaccine could prevent the syndrome. However, identifying functionally important regions in the large VAR2CSA protein is difficult...