Nicaise T Ndam

Summary

Country: France

Publications

  1. ncbi request reprint Cytoadherence phenotype of Plasmodium falciparum-infected erythrocytes is associated with specific pfemp-1 expression in parasites from children with cerebral malaria
    Talleh Almelli
    Institut de recherche pour le developpement IRD, UMR 216 Mère et Enfant face aux infections tropicales, 4, avenue de l Observatoire, Paris 75270, France
    Malar J 13:333. 2014
  2. pmc Low prevalence of the molecular markers of Plasmodium falciparum resistance to chloroquine and sulphadoxine/pyrimethamine in asymptomatic children in Northern Benin
    Aurore Ogouyemi-Hounto
    Unité d Enseignement et de Recherche en Parasitologie Mycologie de la Faculté des Sciences de la Santé 01 BP188, Benin
    Malar J 12:413. 2013
  3. pmc Optimized Pan-species and speciation duplex real-time PCR assays for Plasmodium parasites detection in malaria vectors
    Maurice Marcel Sandeu
    Centre de Recherche Entomologique de Cotonou CREC, Université d Abomey Calavi, Cotonou, Benin
    PLoS ONE 7:e52719. 2012
  4. pmc Prevalence of the molecular marker of Plasmodium falciparum resistance to chloroquine and sulphadoxine/pyrimethamine in Benin seven years after the change of malaria treatment policy
    Aurore Ogouyemi-Hounto
    Faculte des Sciences de la Sante, Laboratoire du centre de lutte intégrée contre le paludisme, Cotonou 01 BP188, Benin
    Malar J 12:147. 2013
  5. pmc Plasmodium falciparum population dynamics in a cohort of pregnant women in Senegal
    Juliette Guitard
    Institut de Recherche pour le Developpement, Universite Paris Descartes, France
    Malar J 9:165. 2010
  6. pmc Plasmodium falciparum parasites causing cerebral malaria share variant surface antigens, but are they specific?
    Nabila Kheliouen
    Institut de Recherche pour le Développement IRD UMR216, Mother and Child faced with tropical infections Unit, Paris, 75006, France
    Malar J 9:220. 2010
  7. pmc Differential evolution of anti-VAR2CSA- IgG3 in primigravidae and multigravidae pregnant women infected by Plasmodium falciparum
    Juliette Guitard
    Institut de recherche pour le developpement IRD, UR010, Mother and Child Health in the Tropics, Universite Paris Descartes, France
    Malar J 7:10. 2008
  8. pmc Identification of glycosaminoglycan binding regions in the Plasmodium falciparum encoded placental sequestration ligand, VAR2CSA
    Mafalda Resende
    Centre for Medical Parasitology, Institute of International Health Immunology and Microbiology, University of Copenhagen, Department of Clinical Microbiology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
    Malar J 7:104. 2008
  9. ncbi request reprint Towards a vaccine against pregnancy-associated malaria
    N Tuikue Ndam
    Institut de Recherche pour le Developpement, UR010, Laboratoire de Parasitologie, Universite Paris Descartes, IFR 71, 4, avenue de l Observatoire, 75006 Paris, France
    Parasite 15:515-21. 2008
  10. pmc Plasmodium falciparum transcriptome analysis reveals pregnancy malaria associated gene expression
    Nicaise Tuikue Ndam
    Institut de Recherche pour le Developpement, UR010 at Université Paris Descartes, Mother and Child Health in the Tropics, Faculte de Pharmacie, Paris, France
    PLoS ONE 3:e1855. 2008

Collaborators

  • Nicolas Moiroux
  • Morten A Nielsen
  • Vincent Corbel
  • Thomas Lavstsen
  • Juliette Guitard
  • Ali Salanti
  • Philippe Deloron
  • Emmanuel Bischoff
  • Aurore Ogouyemi-Hounto
  • Achille Massougbodji
  • Nicaise Tuikue Ndam
  • Talleh Almelli
  • Jean Phillipe Chippaux
  • Dorothée Kindé Gazard
  • Carmine Azagnandji
  • Mourchidath Bello
  • Azizath Moussiliou
  • Maurice Marcel Sandeu
  • Pascal Bigey
  • Firmine Viwami
  • Nabila Kheliouen
  • N Tuikue Ndam
  • Mafalda Resende
  • Rachida Tahar
  • Charles Ahouansou
  • Gratien Sagbo
  • Maroufou J Alao
  • Sem Ezimegnon
  • Annick Amoussou
  • Lucette Koussihoude
  • Elvire Ollo
  • Gildas Fadégnon
  • Sitou d'Almeida
  • Gilles G Padonou
  • Mickaël Quiviger
  • Justin Doritchamou
  • Aude Couturier
  • Sedami Gnidehou
  • Daniel Scherman
  • Christophe Rogier
  • Nicaise Tuikue-Ndam
  • Francis Lalya
  • Else C Eboumbou Moukoko
  • Agnes Aubouy
  • Thor G Theander
  • Pernille Andersen
  • Thor Theander
  • Adam F Sander
  • Peter H David
  • Sisse B Ditlev
  • Jean Yves Coppee
  • Caroline Proux
  • Madeleine Dahlbäck
  • Alioune Gaye

Detail Information

Publications11

  1. ncbi request reprint Cytoadherence phenotype of Plasmodium falciparum-infected erythrocytes is associated with specific pfemp-1 expression in parasites from children with cerebral malaria
    Talleh Almelli
    Institut de recherche pour le developpement IRD, UMR 216 Mère et Enfant face aux infections tropicales, 4, avenue de l Observatoire, Paris 75270, France
    Malar J 13:333. 2014
    ..falciparum erythrocyte membrane protein-1 (PfEMP-1) and human receptors such as CD36 and ICAM-1. The relationship between the expression of PfEMP-1 variants and cytoadherence phenotype in the pathology of malaria is not well established...
  2. pmc Low prevalence of the molecular markers of Plasmodium falciparum resistance to chloroquine and sulphadoxine/pyrimethamine in asymptomatic children in Northern Benin
    Aurore Ogouyemi-Hounto
    Unité d Enseignement et de Recherche en Parasitologie Mycologie de la Faculté des Sciences de la Santé 01 BP188, Benin
    Malar J 12:413. 2013
    ..falciparum and the prevalence of P. falciparum molecular markers that are associated with resistance to CQ and SP in northern Benin seven years after the new policy was instituted...
  3. pmc Optimized Pan-species and speciation duplex real-time PCR assays for Plasmodium parasites detection in malaria vectors
    Maurice Marcel Sandeu
    Centre de Recherche Entomologique de Cotonou CREC, Université d Abomey Calavi, Cotonou, Benin
    PLoS ONE 7:e52719. 2012
    ..Here, we optimized multiplex real-time PCR assays to accurately detect minor populations in mixed infection with multiple Plasmodium species in the African malaria vectors Anopheles gambiae and Anopheles funestus...
  4. pmc Prevalence of the molecular marker of Plasmodium falciparum resistance to chloroquine and sulphadoxine/pyrimethamine in Benin seven years after the change of malaria treatment policy
    Aurore Ogouyemi-Hounto
    Faculte des Sciences de la Sante, Laboratoire du centre de lutte intégrée contre le paludisme, Cotonou 01 BP188, Benin
    Malar J 12:147. 2013
    ..The objective of this study was to determinate the prevalence of Plasmodium falciparum molecular markers that are associated with resistance to CQ and SP in Benin seven years after the new policy was instituted...
  5. pmc Plasmodium falciparum population dynamics in a cohort of pregnant women in Senegal
    Juliette Guitard
    Institut de Recherche pour le Developpement, Universite Paris Descartes, France
    Malar J 9:165. 2010
    ..VAR2CSA is the main candidate for a pregnancy malaria vaccine, but vaccine development may be complicated by its sequence polymorphism...
  6. pmc Plasmodium falciparum parasites causing cerebral malaria share variant surface antigens, but are they specific?
    Nabila Kheliouen
    Institut de Recherche pour le Développement IRD UMR216, Mother and Child faced with tropical infections Unit, Paris, 75006, France
    Malar J 9:220. 2010
    ..This study investigated the antibody response specifically directed against VSA expressed by parasites isolated from individuals presenting a given type of clinical presentation...
  7. pmc Differential evolution of anti-VAR2CSA- IgG3 in primigravidae and multigravidae pregnant women infected by Plasmodium falciparum
    Juliette Guitard
    Institut de recherche pour le developpement IRD, UR010, Mother and Child Health in the Tropics, Universite Paris Descartes, France
    Malar J 7:10. 2008
    ..Pregnant women develop protective anti-VSA IgG1 and IgG3 when infected by Plasmodium falciparum. The major target of IgG from serum of infected pregnant women is VAR2CSA...
  8. pmc Identification of glycosaminoglycan binding regions in the Plasmodium falciparum encoded placental sequestration ligand, VAR2CSA
    Mafalda Resende
    Centre for Medical Parasitology, Institute of International Health Immunology and Microbiology, University of Copenhagen, Department of Clinical Microbiology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
    Malar J 7:104. 2008
    ..It is thus of high priority to define minimal ligand binding regions throughout the VAR2CSA molecule...
  9. ncbi request reprint Towards a vaccine against pregnancy-associated malaria
    N Tuikue Ndam
    Institut de Recherche pour le Developpement, UR010, Laboratoire de Parasitologie, Universite Paris Descartes, IFR 71, 4, avenue de l Observatoire, 75006 Paris, France
    Parasite 15:515-21. 2008
    ..However, despite particular structure and interclonal conservation of VAR2CSA among other PfEMP1, significant challenges still exist concerning the development of a VAR2CSA-based vaccine with profound efficacy...
  10. pmc Plasmodium falciparum transcriptome analysis reveals pregnancy malaria associated gene expression
    Nicaise Tuikue Ndam
    Institut de Recherche pour le Developpement, UR010 at Université Paris Descartes, Mother and Child Health in the Tropics, Faculte de Pharmacie, Paris, France
    PLoS ONE 3:e1855. 2008
    ..Recent advances on the molecular basis of virulence and immune evasion have helped identify var2csa as a PAM-specific var gene...
  11. ncbi request reprint The NTS-DBL2X region of VAR2CSA induces cross-reactive antibodies that inhibit adhesion of several Plasmodium falciparum isolates to chondroitin sulfate A
    Pascal Bigey
    Unite de Pharmacologie Chimique et Genetique, Universite Paris Descartes, ENSCP Chimie ParisTech, CNRS UMR8151, INSERM U 1022, France
    J Infect Dis 204:1125-33. 2011
    ..Acquired anti-VAR2CSA antibodies have been associated with improved pregnancy outcomes, suggesting a vaccine could prevent the syndrome. However, identifying functionally important regions in the large VAR2CSA protein is difficult...