- Reconstructing the phylogenetic history of long-term effective population size and life-history traits using patterns of amino acid replacement in mitochondrial genomes of mammals and birdsBenoit Nabholz
Institut des Sciences de l Evolution, UMR 5554 CNRS, Universite Montpellier II, France
Genome Biol Evol 5:1273-90. 2013..Altogether, our work represents a further step toward a more comprehensive phylogenetic reconstruction of the evolution of life-history and of the population-genetics environment. ..
- Strong variations of mitochondrial mutation rate across mammals--the longevity hypothesisBenoit Nabholz
Institut des Sciences de l Evolution CC64, Centre National de la Recherche Scientifique Université Montpellier 2, Montpellier, France
Mol Biol Evol 25:120-30. 2008..We propose that natural selection tends to decrease the mitochondrial mutation rate in long-lived species, in agreement with the mitochondrial theory of aging...
- Determination of mitochondrial genetic diversity in mammalsBenoit Nabholz
CNRS UMR 5554 Institut des Sciences de l Evolution, Montpellier, France
Genetics 178:351-61. 2008..They suggest that, even in the absence of selection, mtDNA genetic diversity is essentially unpredictable, knowing species biology, and probably uncorrelated to species abundance...
- The erratic mitochondrial clock: variations of mutation rate, not population size, affect mtDNA diversity across birds and mammalsBenoit Nabholz
Université Montpellier 2 CNRS UMR 5554 Institut des Sciences de l Evolution Place E Bataillon CC064, Montpellier, France
BMC Evol Biol 9:54. 2009..These properties make birds the ideal model to directly test for population size effects, and to discriminate between competing hypotheses about the causes of substitution rate variation...
- Inverse relationship between longevity and evolutionary rate of mitochondrial proteins in mammals and birdsNicolas Galtier
Institut des Sciences de l Evolution, Université Montpellier 2 CNRS UMR 5554, Place E Bataillon, 34095 Montpellier, France
Mitochondrion 9:51-7. 2009..This is because his interpretation invokes adaptation as the single evolutionary force at work, disregarding the effects of mutation, genetic drift, and purifying selection...
- An evolutionary genome scan for longevity-related natural selection in mammalsRichard W Jobson
Institut des Sciences de l Evolution, CNRS UMR 5554, Universite Montpellier 2, Montpellier, France
Mol Biol Evol 27:840-7. 2010..In this study, we uncovered the way natural selection has completed this task during mammalian evolution. Cellular membrane and extracellular collagen composition, not genome integrity, have apparently been the optimized features...
- Mitochondrial whims: metabolic rate, longevity and the rate of molecular evolutionNicolas Galtier
Institut des Sciences de l Evolution, CNRS UMR 5554, Universite Montpellier 2, Place E Bataillon, 34095 Montpellier, France
Biol Lett 5:413-6. 2009..We suggest that natural selection could act to reduce the (somatic) mtDNA mutation rate in long-lived species, in agreement with the mitochondrial theory of ageing...
- Transcriptome population genomics reveals severe bottleneck and domestication cost in the African rice (Oryza glaberrima)Benoit Nabholz
Institut des Sciences de l Evolution Montpellier, UMR CNRS UM2 5554, University Montpellier II, Montpellier, France UMR AGAP 1334, Montpellier SupAgro, Montpellier, France
Mol Ecol 23:2210-27. 2014..This work represents the first genome-wide survey of the African rice genetic diversity and paves the way for further comparison between the African and the Asian rice, notably regarding the genetics underlying domestication traits...
- Reference-free population genomics from next-generation transcriptome data and the vertebrate-invertebrate gapPhilippe Gayral
Universite Montpellier 2, CNRS UMR 5554, Institut des Sciences de l Evolution de Montpellier, Montpellier, France
PLoS Genet 9:e1003457. 2013..This study opens promising perspective regarding genome-wide population analyses of non-model organisms and the influence of population size on non-synonymous versus synonymous diversity...