Najat Mourra

Summary

Country: France

Publications

  1. doi request reprint Perivascular epithelioid cell tumor: the first malignant case report in the pancreas
    Najat Mourra
    Department of Pathology, Hopital Saint Antoine, 75012 Paris, France
    Appl Immunohistochem Mol Morphol 21:e1-4. 2013
  2. doi request reprint Metastatic tumors to the colon and rectum: a multi-institutional study
    Najat Mourra
    Department of Pathology, Hopital St Antoine, AP HP, 184 rue du Faubourg St Antoine, 75012 Paris, France
    Arch Pathol Lab Med 136:1397-401. 2012
  3. doi request reprint Colorectal duplication in adults: report of seven cases and review of the literature
    Najat Mourra
    Department of Pathology, Hopital Saint Antoine, AP HP, Paris, France
    J Clin Pathol 63:1080-3. 2010
  4. doi request reprint Ulipristal acetate does not impact human normal breast tissue
    Laudine Communal
    Inserm UPMC, UMRS 938, Hopital Saint Antoine, 75012 Parris, France
    Hum Reprod 27:2785-98. 2012
  5. ncbi request reprint Tissue microarray technology: validation in colorectal carcinoma and analysis of p53, hMLH1, and hMSH2 immunohistochemical expression
    Florence Jourdan
    Department of Pathology, Hopital Saint Antoine, 184 rue du Faubourg Saint Antoine, 75012 Paris, France
    Virchows Arch 443:115-21. 2003
  6. doi request reprint Lumboaortic and iliac lymphadenectomy for lymph node recurrence of colorectal cancer: prognostic value of the MSI phenotype
    Jeremie H Lefevre
    Department of Digestive Surgery, Hospital Saint Antoine AP HP, University Paris VI Pierre and Marie Curie, 184 rue du Faubourg Saint Antoine, 75012, Paris, France
    Ann Surg Oncol 15:2433-8. 2008
  7. doi request reprint High-resolution genotyping of chromosome 8 in colon adenocarcinomas reveals recurrent break point but no gene mutation in the 8p21 region
    Najat Mourra
    CHU St Antoine, Department of Pathology, Paris, France
    Diagn Mol Pathol 17:90-3. 2008
  8. doi request reprint Glucocorticoid receptor activity discriminates between progesterone and medroxyprogesterone acetate effects in breast cells
    Aurélie Courtin
    Inserm UPMC, UMRS 938, Hopital Saint Antoine, Paris, France
    Breast Cancer Res Treat 131:49-63. 2012
  9. pmc Implication of MYH in colorectal polyposis
    Jeremie H Lefevre
    Department of Digestive Surgery, Hopital Saint Antoine AP HP, University Pierre et Marie Curie, Paris, France
    Ann Surg 244:874-9; discussion 879-80. 2006
  10. ncbi request reprint Lymph node metastases of prostatic adenocarcinoma in the mesorectum in patients with adenocarcinoma or villous tumor of the rectum with collision phenomenon in a single lymph node: report of five cases
    Najat Mourra
    Department of Pathology, Hopital Saint Antoine, Assistance Public Hôpitaux de Paris, Universite Pierre et Marie Curie, 184 rue du Faubourg Saint Antoine, 75012 Paris, France
    Dis Colon Rectum 48:384-9. 2005

Collaborators

Detail Information

Publications32

  1. doi request reprint Perivascular epithelioid cell tumor: the first malignant case report in the pancreas
    Najat Mourra
    Department of Pathology, Hopital Saint Antoine, 75012 Paris, France
    Appl Immunohistochem Mol Morphol 21:e1-4. 2013
    ..The patient developed liver metastases 6 months after surgery. Although mostly benign, thorough sampling of the PEComa is mandatory, to rule out malignant behavior whatever the location of the tumor is...
  2. doi request reprint Metastatic tumors to the colon and rectum: a multi-institutional study
    Najat Mourra
    Department of Pathology, Hopital St Antoine, AP HP, 184 rue du Faubourg St Antoine, 75012 Paris, France
    Arch Pathol Lab Med 136:1397-401. 2012
    ..Objective.-To determine the incidence of truly colorectal metastases, and subsequent clinicopathologic findings, in a substantial colorectal cancer population collected from 7 European centers...
  3. doi request reprint Colorectal duplication in adults: report of seven cases and review of the literature
    Najat Mourra
    Department of Pathology, Hopital Saint Antoine, AP HP, Paris, France
    J Clin Pathol 63:1080-3. 2010
    ..Colorectal duplications (CDDs) occur in only 6.8% of cases, rarely in adults, and are revealed by abdominal pain and intestinal obstruction. Malignant changes are uncommon, but are most often found in the colon...
  4. doi request reprint Ulipristal acetate does not impact human normal breast tissue
    Laudine Communal
    Inserm UPMC, UMRS 938, Hopital Saint Antoine, 75012 Parris, France
    Hum Reprod 27:2785-98. 2012
    ..The aim of this study was to determine UPA actions mediated by PR and glucocorticoid receptor (GR) in normal and transformed breast...
  5. ncbi request reprint Tissue microarray technology: validation in colorectal carcinoma and analysis of p53, hMLH1, and hMSH2 immunohistochemical expression
    Florence Jourdan
    Department of Pathology, Hopital Saint Antoine, 184 rue du Faubourg Saint Antoine, 75012 Paris, France
    Virchows Arch 443:115-21. 2003
    ..We showed that 48.5% overexpressed p53 and 8.7% lost hMLH1 or hMSH2. Tissue microarray technology, validated in colorectal carcinoma, appears as a useful research tool for rapid analysis of the clinical interest of molecular alterations...
  6. doi request reprint Lumboaortic and iliac lymphadenectomy for lymph node recurrence of colorectal cancer: prognostic value of the MSI phenotype
    Jeremie H Lefevre
    Department of Digestive Surgery, Hospital Saint Antoine AP HP, University Paris VI Pierre and Marie Curie, 184 rue du Faubourg Saint Antoine, 75012, Paris, France
    Ann Surg Oncol 15:2433-8. 2008
    ..The aim of our study was to assess the carcinological results of lymphadenectomy for ILNR and to identify prognostic factors that may be used to select patients for this aggressive surgical approach...
  7. doi request reprint High-resolution genotyping of chromosome 8 in colon adenocarcinomas reveals recurrent break point but no gene mutation in the 8p21 region
    Najat Mourra
    CHU St Antoine, Department of Pathology, Paris, France
    Diagn Mol Pathol 17:90-3. 2008
    ..No mutation was found, suggesting more complex mechanisms of inactivation or side effects of chromosome arm 8q duplication, which might be up-regulating oncogenes not located within the deleted region...
  8. doi request reprint Glucocorticoid receptor activity discriminates between progesterone and medroxyprogesterone acetate effects in breast cells
    Aurélie Courtin
    Inserm UPMC, UMRS 938, Hopital Saint Antoine, Paris, France
    Breast Cancer Res Treat 131:49-63. 2012
    ..The consequences of MPA glucocorticoid potencies as well as the importance of GR in breast tissue merit a reappraisal...
  9. pmc Implication of MYH in colorectal polyposis
    Jeremie H Lefevre
    Department of Digestive Surgery, Hopital Saint Antoine AP HP, University Pierre et Marie Curie, Paris, France
    Ann Surg 244:874-9; discussion 879-80. 2006
    ..The aim of this study was to determine the frequency of MYH mutations in one large population of polyposis patients without APC mutation identified...
  10. ncbi request reprint Lymph node metastases of prostatic adenocarcinoma in the mesorectum in patients with adenocarcinoma or villous tumor of the rectum with collision phenomenon in a single lymph node: report of five cases
    Najat Mourra
    Department of Pathology, Hopital Saint Antoine, Assistance Public Hôpitaux de Paris, Universite Pierre et Marie Curie, 184 rue du Faubourg Saint Antoine, 75012 Paris, France
    Dis Colon Rectum 48:384-9. 2005
    ..We report five patients with metastatic prostatic carcinoma to mesorectal lymph nodes, with the "collision phenomenon" in one lymph node. The diagnosis of prostate cancer was clinically unsuspected in two cases...
  11. ncbi request reprint Anatomic and pathologic findings at external phased-array pelvic MR imaging after surgery for anorectal disease
    Christine Hoeffel
    Department of Radiology, Hopital Saint Antoine, 184 rue du Faubourg Saint Antoine, 75571 Paris Cedex 12, France
    Radiographics 26:1391-407. 2006
    ..Thus, familiarity with the appearances of postoperative anatomic changes, complications, and tumor recurrence is essential for accurate MR imaging evaluation after surgery for anorectal disease...
  12. doi request reprint Adrenalectomy for clinically isolated metastasis from colorectal carcinoma: report of eight cases
    Najat Mourra
    Department of Pathology, Hopital St Antoine, Paris, France
    Dis Colon Rectum 51:1846-9. 2008
    ..Metastasis to the adrenal glands is a relatively frequent finding at autopsy. Adrenal metastasis of colorectal carcinoma is rare (14 percent). Isolated adrenal metastasis is even rarer, and presents a therapeutic dilemma...
  13. doi request reprint Mucinous cystadenoma of the mesocolon, a rare entity frequently presenting with features of malignity: two case reports and review of the literature
    François Cauchy
    Department of General and Digestive Surgery, University Pierre and Marie Curie, Paris VI, Hopital Saint Antoine, 184, rue du Faubourg St Antoine, 75012 Paris, France
    Clin Res Hepatol Gastroenterol 36:e12-6. 2012
    ..Recently, they have been included in an updated classification of mesenteric cysts and cystic tumors. The WHO classification (ICD 10) divides them into three subcategories according to their malignant behavior...
  14. ncbi request reprint Microsatellite instability in colorectal carcinoma. The comparison of immunohistochemistry and molecular biology suggests a role for hMSH6 [correction of hMLH6] immunostaining
    Valerie Rigau
    Department of Pathology, AP HP, Hopital Saint Antoine, Paris, France
    Arch Pathol Lab Med 127:694-700. 2003
    ..The identification of cancers associated with MSI requires classical molecular testing as the gold standard...
  15. ncbi request reprint MRI of rectal disorders
    Christine C Hoeffel
    Department of Radiology, Université Paris Descartes Faculté de Medecine Cochin Port Royal, Hopital Saint Antoine, 184 rue du Faubourg, Saint Antoine 75571, Paris Cedex 12, France
    AJR Am J Roentgenol 187:W275-84. 2006
    ..CONCLUSION: A wide spectrum of disease processes can involve the rectum in adults. MRI is the technique of choice in the definitive diagnosis of these disease conditions, mainly because of its superior tissue contrast differentiation...
  16. doi request reprint Clinical challenges and images in GI. Extrahepatic biliary cystadenoma with mesenchymal stroma
    Najat Mourra
    Department of Pathology, Hopital St Antoine, Paris, France
    Gastroenterology 134:1295, 1637. 2008
  17. ncbi request reprint Assessment of MRI and MRCP in diagnosis of biliary cystadenoma and cystadenocarcinoma
    Maïté Lewin
    Department of Radiology, Saint Antoine University Hospital, Assistance Publique des Hopitaux de Paris, 184 rue du Faubourg Saint Antoine, 75012, Paris, France
    Eur Radiol 16:407-13. 2006
    ..Gadolinium-enhanced MRI in combination with MRCP is a valuable tool for the diagnosis of BCA or BCAC. However, no specific information is gained for POS detection...
  18. doi request reprint Isolated metastatic tumors to the pancreas: Hôpital St-Antoine experience
    Najat Mourra
    Department of Pathology, Hopital St Antoine, AP HP, Paris, France
    Pancreas 39:577-80. 2010
    ..The leading sources of metastases are breast, lung, kidney, and skin (melanoma). We present our experience with 12 cases of isolated pancreatic metastasis...
  19. doi request reprint Multiple stomas for recurrent life-threatening gastrointestinal bleeding: report of a case
    Jeremie H Lefevre
    Department of Digestive Surgery, Hospital Saint Antoine AP HP, Paris, University Paris VI Pierre and Marie Curie, Paris, France
    Dis Colon Rectum 51:1714-8. 2008
    ..This case report is followed by a review of the literature of the management of lower gastrointestinal bleeding...
  20. pmc Hepatocellular adenoma displaying a HNF1alpha inactivation in a patient with familial adenomatous polyposis coli
    Emmanuelle Jeannot
    INSERM, U674, IUH, Universite Paris 7, Paris, France
    J Hepatol 45:883-6. 2006
    ..Altogether, these results suggest that benign hepatocellular carcinogenesis may be dependent on or independent of the Wnt/beta-catenin pathway in patients with FAP...
  21. ncbi request reprint Malignant deciduoid mesothelioma: a diagnostic challenge
    Najat Mourra
    Department of Pathology, Hopital St Antoine, Paris, France
    Arch Pathol Lab Med 129:403-6. 2005
    ..The patient died 14 months after the first operation. This observation confirms the poor prognosis of this entity and the importance of the differential diagnosis of pseudotumoral deciduosis...
  22. doi request reprint MYH biallelic mutation can inactivate the two genetic pathways of colorectal cancer by APC or MLH1 transversions
    Jeremie H Lefevre
    Department of Digestive Surgery, Hopital Saint Antoine AP HP, University Pierre et Marie Curie Paris VI, 184 rue du Faubourg Saint Antoine, 75571 Paris, France
    Fam Cancer 9:589-94. 2010
    ..588 + 5G > T) leading to a complete deletion of exon 7 at the RNA level. This observation demonstrates that MLH1 can be a target of MYH transversions leading to MSI phenotype...
  23. doi request reprint Clinical challenges and images in GI. Esophageal tubular duplication
    Najat Mourra
    Department of Pathology, Hopital St Antoine, Paris, France
    Gastroenterology 134:669, 899. 2008
  24. ncbi request reprint High frequency of chromosome 14 deletion in early-onset colon cancer
    Najat Mourra
    Department of Pathology, Saint Antoine Hospital, Paris, France
    Dis Colon Rectum 50:1881-6. 2007
    ..This study was designed to depict the genetic mechanisms underlying early-onset microsatellite stable colon cancers...
  25. ncbi request reprint Unusual adrenal incidentalomas: magnetic resonance imaging features with pathological correlation
    Christine Hoeffel
    Université Paris Descartes Faculté Cochin Port Royal, Paris, France
    J Comput Assist Tomogr 30:917-25. 2006
    ..When possible, they are correlated with the findings at gross and microscopic analysis, to help in understanding the mechanisms by which magnetic resonance imaging may aid in the characterization of the incidental adrenal mass...
  26. ncbi request reprint Epithelioid solitary fibrous tumor in the ischioanal fossa
    Najat Mourra
    Department of Pathology, Hopital St Antoine, 184, rue du Faubourg St Antoine, 75012 Paris, France
    Virchows Arch 446:674-6. 2005
  27. ncbi request reprint Ex vivo sentinel lymph node mapping in colorectal cancer
    Stephen W Bell
    Department of Digestive Surgery, Saint Antoine Hospital, AP HP, CancerEst, Universite Pierre et Marie Curie, Paris, France
    Dis Colon Rectum 48:74-9. 2005
    ..Most published series have used the in vivo technique and only three studies have been published in which the ex vivo technique was used. The aim of this study was to report the results of a larger study of ex vivo sentinel node mapping...
  28. ncbi request reprint Presacral neuroendocrine carcinoma developed in a tailgut cyst: report of a case
    Najat Mourra
    Department of Pathology, Hopital Saint Antoine, 184 rue du Faubourg St Antoine, AP HP, 75012 Paris, France
    Dis Colon Rectum 46:411-3. 2003
    ..To the best of our knowledge this is only the second such tumor reported in the literature...
  29. ncbi request reprint [Macroscopic examination of esophagectomy specimens]
    Jean Francois Flejou
    Service d Anatomie et de Cytologie Pathologiques, Hopital Saint Antoine, AP HP, 184, rue du Faubourg St Antoine, 75571, Paris Cedex 12
    Ann Pathol 23:371-8. 2003
    ..This article describes a protocol for the examination of these specimens in surgical pathology departments...
  30. doi request reprint Glucocorticoid receptor and breast cancer
    Myriam Vilasco
    Inserm UPMC, UMRS 938, Hopital Saint Antoine, 184 rue du Faubourg Saint Antoine, 75012, Paris, France
    Breast Cancer Res Treat 130:1-10. 2011
    ..Finally, we discuss the participation of GR in breast tumorigenesis under hormone replacement therapy...
  31. ncbi request reprint Mucinous colon carcinomas with microsatellite instability have a lower microvessel density and lower vascular endothelial growth factor expression
    Dominique Wendum
    Department of Pathology, Hopital Saint Antoine, AP HP, 184 rue du Faubourg Saint Antoine, 75571 Paris Cedex 12, France
    Virchows Arch 442:111-7. 2003
    ..A low COX-2 expression could be related to the medullary phenotype. However, this has to be confirmed in a larger series. Finally, the low MVD of MSI+ mucinous colon adenocarcinomas could participate in their overall better prognosis...
  32. ncbi request reprint Involvement of Meckel diverticulum in Crohn disease associated with pancreatic heterotopia
    Najat Mourra
    Department of Pathology, Hopital St Antoine, Paris, France
    Arch Pathol Lab Med 127:E99-E100. 2003
    ..We report herein the presence of Crohn disease within a Meckel diverticulum, with a normal small bowel immediately adjacent to the diverticulum, associated with pancreatic heterotopia...