Djavad Mossalayi

Summary

Country: France

Publications

  1. pmc Molecular blocking of CD23 supports its role in the pathogenesis of arthritis
    Jérome Rambert
    Groupe Thérapeutiques d inflammation et d infection, Laboratoire d Immunologie et de Parasitologie, UFR Sciences Pharmaceutiques, Universite Bordeaux 2, Bordeaux, France
    PLoS ONE 4:e4834. 2009
  2. pmc Destructive arthritis in a patient with chikungunya virus infection with persistent specific IgM antibodies
    Denis Malvy
    Travel Clinics and Tropical Disease Unit, Department of Internal Medicine, Infectious Diseases and Tropical Medicine, University Hospital Center, Bordeaux, F 33075 France
    BMC Infect Dis 9:200. 2009
  3. pmc CD23 mediates antimycobacterial activity of human macrophages
    M Djavad Mossalayi
    Laboratoire d Immunologie et Parasitologie, Faculte de Pharmacie, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, 33076 Bordeaux, France
    Infect Immun 77:5537-42. 2009
  4. doi A role of IgE and CD23/NO immune pathway in age-related resistance of Lewis rats to Plasmodium berghei Anka?
    Innocent Safeukui
    EA 3677, Bases thérapeutiques des inflammations et infections, Université Victor Segalen Bordeaux II, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    Microbes Infect 10:1411-6. 2008
  5. doi Synthesis and evaluation of the antiproliferative activity of novel pyrrolo[1,2-a]quinoxaline derivatives, potential inhibitors of Akt kinase. Part II
    Vanessa Desplat
    PPF Médicaments Parasitologie, UFR des Sciences Pharmaceutiques, Universite Bordeaux 2, Bordeaux, France
    J Enzyme Inhib Med Chem 25:204-15. 2010
  6. ncbi Synthesis of new pyrrolo[1,2-a]quinoxaline derivatives as potential inhibitors of Akt kinase
    Vanessa Desplat
    PPF Médicaments Parasitologie, UFR des Sciences Pharmaceutiques, Universite Bordeaux 2, Bordeaux Cedex, France
    J Enzyme Inhib Med Chem 23:648-58. 2008
  7. ncbi Synthesis of new 4-(E)-alkenylpyrrolo[1,2-a]quinoxalines as antileishmanial agents by Suzuki-Miyaura cross-coupling reactions
    Jean Guillon
    EA 4138 Pharmacochimie, UFR des Sciences Pharmaceutiques, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    J Enzyme Inhib Med Chem 22:541-9. 2007
  8. ncbi Synthesis, analytical behaviour and biological evaluation of new 4-substituted pyrrolo[1,2-a]quinoxalines as antileishmanial agents
    Jean Guillon
    EA 2962 Pharmacochimie, UFR des Sciences Pharmaceutiques, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    Bioorg Med Chem 15:194-210. 2007
  9. pmc Rutoside decreases human macrophage-derived inflammatory mediators and improves clinical signs in adjuvant-induced arthritis
    Tina Kauss
    Department of Immunology and Parasitology, EA3677, School of Pharmacy, Bordeaux 2 University, 146 rue Leo Saignat, 33076 Bordeaux, France
    Arthritis Res Ther 10:R19. 2008
  10. ncbi Arginases in parasitic diseases
    Philippe Vincendeau
    Equipe d accueil Immunologie moléculaire et Parasitologie, Universite de Bordeaux II, 146 rue Leo Saignat, Bordeaux 33076, France
    Trends Parasitol 19:9-12. 2003

Collaborators

Detail Information

Publications14

  1. pmc Molecular blocking of CD23 supports its role in the pathogenesis of arthritis
    Jérome Rambert
    Groupe Thérapeutiques d inflammation et d infection, Laboratoire d Immunologie et de Parasitologie, UFR Sciences Pharmaceutiques, Universite Bordeaux 2, Bordeaux, France
    PLoS ONE 4:e4834. 2009
    ..Increased CD23 expression is found in patients during allergic reactions and rheumatoid arthritis while its physiopathologic role in these diseases remains to be clarified...
  2. pmc Destructive arthritis in a patient with chikungunya virus infection with persistent specific IgM antibodies
    Denis Malvy
    Travel Clinics and Tropical Disease Unit, Department of Internal Medicine, Infectious Diseases and Tropical Medicine, University Hospital Center, Bordeaux, F 33075 France
    BMC Infect Dis 9:200. 2009
    ..Up to now, the pathophysiology of the chronic stage is poorly understood...
  3. pmc CD23 mediates antimycobacterial activity of human macrophages
    M Djavad Mossalayi
    Laboratoire d Immunologie et Parasitologie, Faculte de Pharmacie, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, 33076 Bordeaux, France
    Infect Immun 77:5537-42. 2009
    ..This study reveals a new human immune response mechanism to counter mycobacterial infection involving CD23 and its related ligands...
  4. doi A role of IgE and CD23/NO immune pathway in age-related resistance of Lewis rats to Plasmodium berghei Anka?
    Innocent Safeukui
    EA 3677, Bases thérapeutiques des inflammations et infections, Université Victor Segalen Bordeaux II, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    Microbes Infect 10:1411-6. 2008
    ..These data suggest that IgE and CD23/NO could play an important role in the resistance of adult rats experiencing PbA primary intraerythrocytic development...
  5. doi Synthesis and evaluation of the antiproliferative activity of novel pyrrolo[1,2-a]quinoxaline derivatives, potential inhibitors of Akt kinase. Part II
    Vanessa Desplat
    PPF Médicaments Parasitologie, UFR des Sciences Pharmaceutiques, Universite Bordeaux 2, Bordeaux, France
    J Enzyme Inhib Med Chem 25:204-15. 2010
    ....
  6. ncbi Synthesis of new pyrrolo[1,2-a]quinoxaline derivatives as potential inhibitors of Akt kinase
    Vanessa Desplat
    PPF Médicaments Parasitologie, UFR des Sciences Pharmaceutiques, Universite Bordeaux 2, Bordeaux Cedex, France
    J Enzyme Inhib Med Chem 23:648-58. 2008
    ..5 microM, and 1h that inhibited U937 and MCF7 cell lines with IC(50) of 5 and 8 microM, respectively. These two candidates exhibited more potent activities than the reference inhibitor A6730...
  7. ncbi Synthesis of new 4-(E)-alkenylpyrrolo[1,2-a]quinoxalines as antileishmanial agents by Suzuki-Miyaura cross-coupling reactions
    Jean Guillon
    EA 4138 Pharmacochimie, UFR des Sciences Pharmaceutiques, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    J Enzyme Inhib Med Chem 22:541-9. 2007
    ..From a Structure-Activity Relationships point of view, these pharmacological results mainly enlightened the importance of the 4-lateral C6, C7 or C8 alpha-unsaturated trans-alkenyl chain of unsubstituted pyrrolo[1,2-a]quinoxaline moiety...
  8. ncbi Synthesis, analytical behaviour and biological evaluation of new 4-substituted pyrrolo[1,2-a]quinoxalines as antileishmanial agents
    Jean Guillon
    EA 2962 Pharmacochimie, UFR des Sciences Pharmaceutiques, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    Bioorg Med Chem 15:194-210. 2007
    ..Structure-activity relationships enlighten the importance of the 4-substituted alkenyl side chain on the pyrrolo[1,2-a]quinoxaline moiety to modulate the antileishmanial activity...
  9. pmc Rutoside decreases human macrophage-derived inflammatory mediators and improves clinical signs in adjuvant-induced arthritis
    Tina Kauss
    Department of Immunology and Parasitology, EA3677, School of Pharmacy, Bordeaux 2 University, 146 rue Leo Saignat, 33076 Bordeaux, France
    Arthritis Res Ther 10:R19. 2008
    ....
  10. ncbi Arginases in parasitic diseases
    Philippe Vincendeau
    Equipe d accueil Immunologie moléculaire et Parasitologie, Universite de Bordeaux II, 146 rue Leo Saignat, Bordeaux 33076, France
    Trends Parasitol 19:9-12. 2003
  11. pmc Quercetin induces apoptosis of Trypanosoma brucei gambiense and decreases the proinflammatory response of human macrophages
    Maria Mamani-Matsuda
    Laboratoires d Immunologie et de Parasitologie, E A 3677, Bases Thérapeutiques Anti Infectieuses et Anti Inflammatoires, Universite Bordeaux II, France
    Antimicrob Agents Chemother 48:924-9. 2004
    ..These results highlight the potential use of quercetin as an antimicrobial and anti-inflammatory agent for the treatment of African trypanomiasis...
  12. ncbi Plasmodium berghei: dehydroepiandrosterone sulfate reverses chloroquino-resistance in experimental malaria infection; correlation with glucose 6-phosphate dehydrogenase and glutathione synthesis pathway
    Innocent Safeukui
    Unité 3677, Bases thérapeutiques des inflammations et infections, Université Victor Segalen Bordeaux II, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    Biochem Pharmacol 68:1903-10. 2004
    ..This experimental study suggests that DHEAS could be used to potentiate antimalarial action of CQ, particularly on CQ resistant strains...
  13. ncbi Type I interferon signature in the initiation of the immune response in vitiligo
    Antoine Bertolotti
    Department of Dermatology and Pediatric Dermatology, National Centre for Rare Skin Disorders, Saint André and Pellegrin Hospital, Bordeaux, France
    Pigment Cell Melanoma Res 27:398-407. 2014
    ..In contrast, MxA was not detectable in lesional skin, suggesting that IFN-α production is an early event in the progression of the disease. Our data highlight a new innate immune pathway leading to progression of vitiligo...
  14. ncbi Anti-leukemia activity of 7-hydroxy-2-substituted-methyl-5H-oxazolo[3,2-a]pyrimidin-5-one derivatives
    Jean Guillon
    EA 2962 Pharmacochimie, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    J Enzyme Inhib Med Chem 17:391-6. 2002
    ..They were tested for their ability to inhibit proliferation in human Bcr-Abl+ leukemia cells...