Jean Paul Mornon

Summary

Country: France

Publications

  1. doi request reprint Molecular models of the open and closed states of the whole human CFTR protein
    Jean Paul Mornon
    IMPMC, UMR7590, CNRS, Universités Pierre et Marie Curie Paris 6 et Denis Diderot Paris 7, 140 rue de Lourmel, Paris, France
    Cell Mol Life Sci 66:3469-86. 2009
  2. doi request reprint Calcineurin B-like domains in the large regulatory alpha/beta subunits of phosphorylase kinase
    Cathelène Carrière
    Département de Biologie Structurale, Institut de Minéralogie et de Physique des Milieux Condensés, UMR 7590, CNRS, Universités Paris 6 et Paris 7, Paris, France
    Proteins 71:1597-606. 2008
  3. ncbi request reprint Striking conformational change suspected within the phosphoribulokinase dimer induced by interaction with GAPDH
    Fabrice Mouche
    Laboratoire de Minéralogie Cristallographie Paris, CNRS, UMR 7590, Universités Paris 6 et Paris 7, case 115, 4 place Jussieu, 75252 Paris Cedex 05, France
    J Biol Chem 277:6743-9. 2002
  4. ncbi request reprint Isolated ZP-N domains constitute the N-terminal extensions of Zona Pellucida proteins
    Isabelle Callebaut
    Département de Biologie Structurale, IMPMC UMR 7590, Universités Pierre et Marie Curie Paris6, Paris, France
    Bioinformatics 23:1871-4. 2007
  5. pmc A generalized analysis of hydrophobic and loop clusters within globular protein sequences
    Richard Eudes
    Structural Biology Department, IMPMC, CNRS UMR7590, Universités Paris 6 and Paris 7, case 115, 4 place Jussieu, 75252 Paris Cedex 05, France
    BMC Struct Biol 7:2. 2007
  6. pmc Prediction of the general transcription factors associated with RNA polymerase II in Plasmodium falciparum: conserved features and differences relative to other eukaryotes
    Isabelle Callebaut
    Centre National de la Recherche Scientifique CNRS UMR7590, Universités Paris 6 et Paris 7, Département de Biologie Structurale, IMPMC, 75252 Paris Cedex 05, France
    BMC Genomics 6:100. 2005
  7. pmc C terminus of nucleotide binding domain 1 contains critical features for cystic fibrosis transmembrane conductance regulator trafficking and activation
    Arnaud Billet
    Institut de Physiologie et Biologie Cellulaires, Universite de Poitiers, CNRS, 86022 Poitiers, France
    J Biol Chem 285:22132-40. 2010
  8. doi request reprint CFTR: effect of ICL2 and ICL4 amino acids in close spatial proximity on the current properties of the channel
    Arnaud Billet
    Institut de Physiologie et Biologie Cellulaires, Universite de Poitiers, CNRS, Poitiers, France
    J Cyst Fibros 12:737-45. 2013
  9. pmc Delineation of the Xrcc4-interacting region in the globular head domain of cernunnos/XLF
    Laurent Malivert
    INSERM, Hôpital Necker Enfants Malades U768, Unité de Développement Normal et Pathologique du Système Immunitaire, Paris, France
    J Biol Chem 285:26475-83. 2010
  10. doi request reprint LOTUS, a new domain associated with small RNA pathways in the germline
    Isabelle Callebaut
    IMPMC UMR7590, Universite Pierre et Marie Curie Paris 6, Paris, France
    Bioinformatics 26:1140-4. 2010

Collaborators

Detail Information

Publications22

  1. doi request reprint Molecular models of the open and closed states of the whole human CFTR protein
    Jean Paul Mornon
    IMPMC, UMR7590, CNRS, Universités Pierre et Marie Curie Paris 6 et Denis Diderot Paris 7, 140 rue de Lourmel, Paris, France
    Cell Mol Life Sci 66:3469-86. 2009
    ....
  2. doi request reprint Calcineurin B-like domains in the large regulatory alpha/beta subunits of phosphorylase kinase
    Cathelène Carrière
    Département de Biologie Structurale, Institut de Minéralogie et de Physique des Milieux Condensés, UMR 7590, CNRS, Universités Paris 6 et Paris 7, Paris, France
    Proteins 71:1597-606. 2008
    ..This finding, together the identification of significant similarities of domain D with the preceding domain C, may help to understand the molecular mechanism by which PhK alpha and/or beta domain D might regulate PhK activity...
  3. ncbi request reprint Striking conformational change suspected within the phosphoribulokinase dimer induced by interaction with GAPDH
    Fabrice Mouche
    Laboratoire de Minéralogie Cristallographie Paris, CNRS, UMR 7590, Universités Paris 6 et Paris 7, case 115, 4 place Jussieu, 75252 Paris Cedex 05, France
    J Biol Chem 277:6743-9. 2002
    ....
  4. ncbi request reprint Isolated ZP-N domains constitute the N-terminal extensions of Zona Pellucida proteins
    Isabelle Callebaut
    Département de Biologie Structurale, IMPMC UMR 7590, Universités Pierre et Marie Curie Paris6, Paris, France
    Bioinformatics 23:1871-4. 2007
    ....
  5. pmc A generalized analysis of hydrophobic and loop clusters within globular protein sequences
    Richard Eudes
    Structural Biology Department, IMPMC, CNRS UMR7590, Universités Paris 6 and Paris 7, case 115, 4 place Jussieu, 75252 Paris Cedex 05, France
    BMC Struct Biol 7:2. 2007
    ..These species are characterized only by their hydrophobic/non-hydrophobic dichotomy. This analysis has been extended to loop-forming clusters, using an appropriate loop alphabet...
  6. pmc Prediction of the general transcription factors associated with RNA polymerase II in Plasmodium falciparum: conserved features and differences relative to other eukaryotes
    Isabelle Callebaut
    Centre National de la Recherche Scientifique CNRS UMR7590, Universités Paris 6 et Paris 7, Département de Biologie Structurale, IMPMC, 75252 Paris Cedex 05, France
    BMC Genomics 6:100. 2005
    ..In this study, we have used a combination of sensitive sequence analysis methods to predict the existence of several parasite encoded general transcription factors associated with RNA polymerase II...
  7. pmc C terminus of nucleotide binding domain 1 contains critical features for cystic fibrosis transmembrane conductance regulator trafficking and activation
    Arnaud Billet
    Institut de Physiologie et Biologie Cellulaires, Universite de Poitiers, CNRS, 86022 Poitiers, France
    J Biol Chem 285:22132-40. 2010
    ....
  8. doi request reprint CFTR: effect of ICL2 and ICL4 amino acids in close spatial proximity on the current properties of the channel
    Arnaud Billet
    Institut de Physiologie et Biologie Cellulaires, Universite de Poitiers, CNRS, Poitiers, France
    J Cyst Fibros 12:737-45. 2013
    ..We studied molecular determinants, which might distinguish CFTR from standard ABC transporters, and focused on the interface formed by the intracellular loops from the membrane spanning domains...
  9. pmc Delineation of the Xrcc4-interacting region in the globular head domain of cernunnos/XLF
    Laurent Malivert
    INSERM, Hôpital Necker Enfants Malades U768, Unité de Développement Normal et Pathologique du Système Immunitaire, Paris, France
    J Biol Chem 285:26475-83. 2010
    ..Docking the crystal structures of the two factors further validated this probable interaction surface of Cernunnos with X4...
  10. doi request reprint LOTUS, a new domain associated with small RNA pathways in the germline
    Isabelle Callebaut
    IMPMC UMR7590, Universite Pierre et Marie Curie Paris 6, Paris, France
    Bioinformatics 26:1140-4. 2010
    ..This suggests a germline-specific role in the mRNA localization and/or translation or a specific function toward piRNAs...
  11. ncbi request reprint Characterization and study of a kappa-casein-like chymosin-sensitive linkage
    Isabelle Callebaut
    Département de Biologie Structurale, IMPMC, CNRS UMR7590, Universités Paris 6 et Paris 7, case 115, 4 place Jussieu, 75252 Paris Cedex 05, France
    Biochim Biophys Acta 1749:75-80. 2005
    ..The effect of the enzyme activity of chymosin was thus tested on glutamine synthetase. Chymosin cut the latter at the Phe-Met linkage, suggesting that this system may locally resemble the kappa-casein/chymosin complex...
  12. ncbi request reprint Sequence-based modeling of Abeta42 soluble oligomers
    Fabienne Dulin
    Département de Biologie Structurale, IMPMC, CNRS UMR7590, Universités Pierre et Marie Curie Paris 6 et Denis Diderot Paris 7, F 75005 France
    Biopolymers 85:422-37. 2007
    ..The consistency of these models is discussed with respect to available experimental and theoretical data...
  13. ncbi request reprint Cernunnos interacts with the XRCC4 x DNA-ligase IV complex and is homologous to the yeast nonhomologous end-joining factor Nej1
    Isabelle Callebaut
    Département de Biologie Structurale, Institut de Minéralogie et de Physique des Milieux Condensés, CNRS UMR7590, Universités Paris 6 et Paris 7, Paris, F 75005 France
    J Biol Chem 281:13857-60. 2006
    ..Altogether these results shed new lights on the last step, the DNA religation, of the NHEJ pathway...
  14. ncbi request reprint Analysis of fragments induced by simulated lattice protein folding
    Jacques Chomilier
    Equipe Systèmes moléculaires et Biologie structurale, LMCP, Universite Paris 6, CNRS UMR 7590, case 115, 75252 Paris 05, France
    C R Biol 327:431-43. 2004
    ..This aggregation may be a way to accelerate the formation of the native state and enforces the key role played by hydrophobic residues in the formation of the fragments, thus in the folding process itself...
  15. ncbi request reprint EMI domains are widespread and reveal the probable orthologs of the Caenorhabditis elegans CED-1 protein
    Isabelle Callebaut
    Systèmes moléculaires et Biologie structurale, LMCP, CNRS UMR7590, Universités Paris 6 et Paris 7, case 115, 4 place Jussieu, 75252 05 Paris Cedex, France
    Biochem Biophys Res Commun 300:619-23. 2003
    ..Sequence profiles specific of the EMI family of domains led to identify the probable orthologs of the C. elegans CED-1 protein in mammals and insects, which were yet uncovered...
  16. pmc Metallo-beta-lactamase fold within nucleic acids processing enzymes: the beta-CASP family
    Isabelle Callebaut
    Systèmes moléculaires et Biologie structurale, LMCP, CNRS UMR 7590, Universités Paris 6 et Paris 7, case 115, 4 place Jussieu, F 75252 Paris Cedex 05, France
    Nucleic Acids Res 30:3592-601. 2002
    ....
  17. ncbi request reprint OCRE: a novel domain made of imperfect, aromatic-rich octamer repeats
    Isabelle Callebaut
    Département de Biologie Structurale, LMCP, CNRS UMR7590, Universités Paris 6 and Paris 7, case 115, 4 place Jussieu, 75252 Paris Cedex 05, France Isabelle
    Bioinformatics 21:699-702. 2005
    ....
  18. ncbi request reprint Protein secondary structure assignment through Voronoï tessellation
    Franck Dupuis
    Laboratoire de Minéralogie Cristallographie Paris, CNRS UMR 7590, Universités Paris 6 et 7, Paris, France
    Proteins 55:519-28. 2004
    ..The second step focuses on the strand assignment and uses contacts between distant residues. Comparison with several other automatic assignment methods are presented, and the influence of resolution on the assignment is investigated...
  19. doi request reprint The PWAPA cassette: Intimate association of a PHD-like finger and a winged-helix domain in proteins included in histone-modifying complexes
    Isabelle Callebaut
    IMPMC, UMR7590, CNRS, Universite Pierre et Marie Curie, case 115, 4 place Jussieu, 75252 Paris Cedex 05, France
    Biochimie 94:2006-12. 2012
    ..The observations reported here should help to unravel the exact role played by the PWAPA cassette in the different proteins of the PWAPA family, and especially in the antagonistic activities of PcG and TrxG proteins...
  20. doi request reprint 3D mapping of glycogenosis-causing mutations in the large regulatory alpha subunit of phosphorylase kinase
    Cathelène Carrière
    Universite Pierre et Marie Curie Paris 6, IMPMC UMR7590, Paris, F 75005, France
    Biochim Biophys Acta 1782:664-70. 2008
    ..Altogether, these results show that PHKA2 missense mutations or small in-frame deletions/insertions may have a direct impact on the PhK alpha functions and provide a framework for further experimental investigation...
  21. doi request reprint A concanavalin A-like lectin domain in the CHS1/LYST protein, shared by members of the BEACH family
    Agathe Burgess
    INSERM, U768, Paris, F 75015, France
    Bioinformatics 25:1219-22. 2009
    ....