Patrick Moreau

Summary

Country: France

Publications

  1. ncbi request reprint The plant ER-Golgi interface: a highly structured and dynamic membrane complex
    Patrick Moreau
    Laboratoire de Biogenese Membranaire, UMR 5200 CNRS Université de Bordeaux II, Case 92, 146 rue Leo Saignat, F 33076 Bordeaux cedex, France
    J Exp Bot 58:49-64. 2007
  2. ncbi request reprint Phosphatidylserine delivery to endoplasmic reticulum-derived vesicles of plant cells depends on two biosynthetic pathways
    P Vincent
    Laboratoire de Biogenèse Membranaire UMR 5544 CNRS, Universite Victor Segalen Bordeaux 2, France
    FEBS Lett 498:32-6. 2001
  3. doi request reprint Links between lipid homeostasis, organelle morphodynamics and protein trafficking in eukaryotic and plant secretory pathways
    Su Melser
    Laboratoire de Biogenese Membranaire, UMR 5200 Université Bordeaux 2 CNRS, Universite Bordeaux 2, Case 92, 146 rue Leo Saignat, 33076 Bordeaux, France
    Plant Cell Rep 30:177-93. 2011
  4. ncbi request reprint The threonine degradation pathway of the Trypanosoma brucei procyclic form: the main carbon source for lipid biosynthesis is under metabolic control
    Yoann Millerioux
    Centre de Résonance Magnétique des Systèmes Biologiques RMSB, UMR 5536 Université Bordeaux Segalen, CNRS, 146 rue Leo Saignat, 33076, Bordeaux, France
    Mol Microbiol 90:114-29. 2013
  5. doi request reprint Glucosylceramide biosynthesis is involved in Golgi morphology and protein secretion in plant cells
    Su Melser
    Université V Segalen Bordeaux 2, Laboratoire de Biogenese Membranaire, CNRS UMR 5200, 146, rue Leo Saignat, 33076 Bordeaux Cedex, France
    Traffic 11:479-90. 2010
  6. pmc ATP synthesis-coupled and -uncoupled acetate production from acetyl-CoA by mitochondrial acetate:succinate CoA-transferase and acetyl-CoA thioesterase in Trypanosoma
    Yoann Millerioux
    Centre de Résonance Magnétique des Systèmes Biologiques, UMR 5536, Université Bordeaux Segalen, CNRS, 146 rue Leo Saignat, 33076 Bordeaux, France
    J Biol Chem 287:17186-97. 2012
  7. pmc Sec22 and Memb11 are v-SNAREs of the anterograde endoplasmic reticulum-Golgi pathway in tobacco leaf epidermal cells
    Laurent Chatre
    Laboratoire de Biogenese Membranaire, Unité Mixte de Recherche 5200, Centre National de la Recherche Scientifique Université Bordeaux 2, 33076 Bordeaux, France
    Plant Physiol 139:1244-54. 2005
  8. pmc Insights into the role of specific lipids in the formation and delivery of lipid microdomains to the plasma membrane of plant cells
    Maryse Laloi
    Laboratoire de Biogenese Membranaire, Unité Mixte de Recherche 5200 Centre National de la Recherche Scientifique Université Victor Segalen Bordeaux 2, BP 33076 Bordeaux cedex, France
    Plant Physiol 143:461-72. 2007
  9. ncbi request reprint The VLCFA elongase gene family in Arabidopsis thaliana: phylogenetic analysis, 3D modelling and expression profiling
    Jérôme Joubès
    Laboratoire de Biogenese Membranaire, Universite Victor Segalen Bordeaux 2, CNRS, UMR5200, 146 rue Leo Saignat, Case 92, 33076 Bordeaux Cedex, France
    Plant Mol Biol 67:547-66. 2008
  10. pmc Remorin, a solanaceae protein resident in membrane rafts and plasmodesmata, impairs potato virus X movement
    Sylvain Raffaele
    Laboratoire de Biogenese Membranaire, Unité Mixte de Recherche 5200, Centre National de la Recherche Scientifique University of Bordeaux, Bordeaux 33076, France
    Plant Cell 21:1541-55. 2009

Collaborators

Detail Information

Publications24

  1. ncbi request reprint The plant ER-Golgi interface: a highly structured and dynamic membrane complex
    Patrick Moreau
    Laboratoire de Biogenese Membranaire, UMR 5200 CNRS Université de Bordeaux II, Case 92, 146 rue Leo Saignat, F 33076 Bordeaux cedex, France
    J Exp Bot 58:49-64. 2007
    ..This review will focus on some aspects of membrane dynamics that involve coat proteins, SNAREs (soluble N-ethylmaleimide-sensitive factor attachment receptor proteins), lipids, and lipid-interacting proteins...
  2. ncbi request reprint Phosphatidylserine delivery to endoplasmic reticulum-derived vesicles of plant cells depends on two biosynthetic pathways
    P Vincent
    Laboratoire de Biogenèse Membranaire UMR 5544 CNRS, Universite Victor Segalen Bordeaux 2, France
    FEBS Lett 498:32-6. 2001
    ..On the other hand, both enzymes synthesize PS with long chain fatty acids (up to 18 carbon atoms), but these species are given to the EV by PS synthase...
  3. doi request reprint Links between lipid homeostasis, organelle morphodynamics and protein trafficking in eukaryotic and plant secretory pathways
    Su Melser
    Laboratoire de Biogenese Membranaire, UMR 5200 Université Bordeaux 2 CNRS, Universite Bordeaux 2, Case 92, 146 rue Leo Saignat, 33076 Bordeaux, France
    Plant Cell Rep 30:177-93. 2011
    ..Collectively, data of the literature demonstrate the existence of links between protein trafficking, organelle morphology, and lipid metabolism/homeostasis in eukaryotic cells including plant cells...
  4. ncbi request reprint The threonine degradation pathway of the Trypanosoma brucei procyclic form: the main carbon source for lipid biosynthesis is under metabolic control
    Yoann Millerioux
    Centre de Résonance Magnétique des Systèmes Biologiques RMSB, UMR 5536 Université Bordeaux Segalen, CNRS, 146 rue Leo Saignat, 33076, Bordeaux, France
    Mol Microbiol 90:114-29. 2013
    ..We conclude that TDH expression is under control and can be downregulated in response to metabolic perturbations, such as in the PEPCK mutant in which the glycolytic metabolic flux was redirected towards acetate production. ..
  5. doi request reprint Glucosylceramide biosynthesis is involved in Golgi morphology and protein secretion in plant cells
    Su Melser
    Université V Segalen Bordeaux 2, Laboratoire de Biogenese Membranaire, CNRS UMR 5200, 146, rue Leo Saignat, 33076 Bordeaux Cedex, France
    Traffic 11:479-90. 2010
    ....
  6. pmc ATP synthesis-coupled and -uncoupled acetate production from acetyl-CoA by mitochondrial acetate:succinate CoA-transferase and acetyl-CoA thioesterase in Trypanosoma
    Yoann Millerioux
    Centre de Résonance Magnétique des Systèmes Biologiques, UMR 5536, Université Bordeaux Segalen, CNRS, 146 rue Leo Saignat, 33076 Bordeaux, France
    J Biol Chem 287:17186-97. 2012
    ..We concluded that acetate is produced from both ASCT and ACH; however, only ASCT is responsible, together with the F(0)/F(1)-ATP synthase, for ATP production in the mitochondrion...
  7. pmc Sec22 and Memb11 are v-SNAREs of the anterograde endoplasmic reticulum-Golgi pathway in tobacco leaf epidermal cells
    Laurent Chatre
    Laboratoire de Biogenese Membranaire, Unité Mixte de Recherche 5200, Centre National de la Recherche Scientifique Université Bordeaux 2, 33076 Bordeaux, France
    Plant Physiol 139:1244-54. 2005
    ..Our studies suggest that Sec22 and Memb11 are involved in anterograde protein trafficking at the ER-Golgi interface...
  8. pmc Insights into the role of specific lipids in the formation and delivery of lipid microdomains to the plasma membrane of plant cells
    Maryse Laloi
    Laboratoire de Biogenese Membranaire, Unité Mixte de Recherche 5200 Centre National de la Recherche Scientifique Université Victor Segalen Bordeaux 2, BP 33076 Bordeaux cedex, France
    Plant Physiol 143:461-72. 2007
    ....
  9. ncbi request reprint The VLCFA elongase gene family in Arabidopsis thaliana: phylogenetic analysis, 3D modelling and expression profiling
    Jérôme Joubès
    Laboratoire de Biogenese Membranaire, Universite Victor Segalen Bordeaux 2, CNRS, UMR5200, 146 rue Leo Saignat, Case 92, 33076 Bordeaux Cedex, France
    Plant Mol Biol 67:547-66. 2008
    ..The expression patterns in Arabidopsis of the acyl-CoA elongase genes suggest several levels of regulations at the tissular or organ level but also under stress conditions suggesting a complex organization of this multigenic family...
  10. pmc Remorin, a solanaceae protein resident in membrane rafts and plasmodesmata, impairs potato virus X movement
    Sylvain Raffaele
    Laboratoire de Biogenese Membranaire, Unité Mixte de Recherche 5200, Centre National de la Recherche Scientifique University of Bordeaux, Bordeaux 33076, France
    Plant Cell 21:1541-55. 2009
    ..Based on the localization of REM and its impact on virus macromolecular trafficking, we discuss the potential for lipid rafts to act as functional components in plasmodesmata and the plasma membrane...
  11. ncbi request reprint Modulation of Fas-mediated apoptosis by lipid rafts in T lymphocytes
    Patrick Legembre
    Laboratoire Composantes Innées de la Réponse Immunitaire et Différenciation, Centre National de la Recherche Scientifique Unite Mixte de Recherche 5164, University of Bordeaux, France
    J Immunol 176:716-20. 2006
    ..Moreover, our results demonstrate that Fas-induced apoptosis can be controlled at the level of the cytoplasmic membrane...
  12. ncbi request reprint Antibodies to long-chain acyl-CoAs. A new tool for lipid biochemistry
    L Maneta-Peyret
    Universite Victor Segalen Bordeaux 2, CNRS UMR 5544, France
    Biochim Biophys Acta 1389:50-6. 1998
    ..These antibodies represent a new tool for studying long-chain acyl-CoAs. Their use in an immunochemical approach for the study of protein-acyl-CoA interactions is presented...
  13. ncbi request reprint One of the origins of plasma membrane phosphatidylserine in plant cells is a local synthesis by a serine exchange activity
    P Vincent
    , , , 33076, Bordeaux, France
    FEBS Lett 464:80-4. 1999
    ..Therefore, the PS in the plasma membrane of leek cells has two different origins: the intracellular vesicular pathway from the ER and a local synthesis in the plasma membrane...
  14. doi request reprint Lipids of plant membrane rafts
    Jean Luc Cacas
    Laboratoire de Biogenese Membranaire, UMR 5200 CNRS, Universite de Bordeaux, 146 rue Leo Saignat, 33076 Bordeaux, France
    Prog Lipid Res 51:272-99. 2012
    ..We also discuss the potential involvement of rafts in the regulation of plant physiological processes, and further discuss the prospects of future research into plant membrane rafts...
  15. ncbi request reprint Phosphatidylserine increase in rat liver endomembranes during the acute phase response
    P Vincent
    , , 146, , Case 92, 33076 Bordeaux Cedex, France
    Biochimie 83:957-60. 2001
    ..Our studies show that phosphatidylserine synthesis is stimulated during the APR and that this lipid is increased in the endoplasmic reticulum (ER) and the ER-derived vesicles...
  16. ncbi request reprint Evidence for a different metabolism of PC and PE in shoots and roots
    Agnès Hocquellet
    Laboratoire de Biogenese Membranaire, UMR 5200, CNRS Université Victor Segalen Bordeaux 2, 146, rue Leo Saignat, Case 92, 33076 Bordeaux Cedex, France
    Plant Physiol Biochem 43:938-46. 2005
    ..thaliana seedlings, and demonstrated that some specific remodelling of PC and PE by acylation was responsible for the differences in labelling observed in vivo...
  17. pmc Acetate produced in the mitochondrion is the essential precursor for lipid biosynthesis in procyclic trypanosomes
    Loïc Rivière
    Laboratoire de Microbiologie Cellulaire et Moléculaire et Pathogénicité, Unité Mixte de Recherche 5234 Centre National de la Recherche Scientifique, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    Proc Natl Acad Sci U S A 106:12694-9. 2009
    ..To date, Trypanosoma is the only known eukaryotic organism that uses acetate instead of citrate to transfer acetyl groups over the mitochondrial membrane for cytosolic lipid synthesis...
  18. ncbi request reprint Effects of brefeldin A and nordihydroguaiaretic acid on endomembrane dynamics and lipid synthesis in plant cells
    Patricia Merigout
    Laboratoire de Dynamique de la Compartimentation Cellulaire, Institut des Sciences du Vegetal, CNRS UPR 2355, 91198 Cedex, Gif sur Yvette, France
    FEBS Lett 518:88-92. 2002
    ..The importance of phytosterols in membrane architecture and membrane trafficking is discussed...
  19. pmc Amplification of Fas-mediated apoptosis in type II cells via microdomain recruitment
    Patrick Legembre
    Laboratoire CIRID, CNRS UMR 5164, Universite de Bordeaux 2, 146 rue Leo Saignat, Bordeaux 33076, France
    Mol Cell Biol 25:6811-20. 2005
    ....
  20. ncbi request reprint In tobacco leaf epidermal cells, the integrity of protein export from the endoplasmic reticulum and of ER export sites depends on active COPI machinery
    Giovanni Stefano
    Department of Biology, 112 Science Place, University of Saskatchewan, Saskatoon, SK S7N 5E2, Canada
    Plant J 46:95-110. 2006
    ....
  21. ncbi request reprint Immunolocalization of long-chain acyl-CoAs in plant cells
    Paraskevi Diakou
    Laboratoire de Biogenese Membranaire, Universite Victor Segalen Bordeaux 2, CNRS UMR 5544, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    Biochim Biophys Acta 1583:85-90. 2002
    ..Our results demonstrate the value of cryo-methods for the accurate localization of labile metabolites in plant cells...
  22. ncbi request reprint Inhibition of the sterol pathway in leek seedlings impairs phosphatidylserine and glucosylceramide synthesis but triggers an accumulation of triacylglycerols
    Marie Andrée Hartmann
    Institut de Biologie Moléculaire des Plantes CNRS UPR 2357, 28 rue Goethe, 67083 Strasbourg, France
    Biochim Biophys Acta 1583:285-96. 2002
    ..Taken together, the present data emphasize that a coordinated regulation of the biosynthetic pathways of sterols and some specific lipid molecular species could take place during plant membrane biogenesis...
  23. doi request reprint Localization of Fas/CD95 into the lipid rafts on down-modulation of the phosphatidylinositol 3-kinase signaling pathway
    Marie Beneteau
    Centre National de la Recherche Scientifique Unite Mixte de Recherche 5164, 33076 Bordeaux, France
    Mol Cancer Res 6:604-13. 2008
    ..These findings indicate that the antitumoral agent edelfosine down-modulates the PI3K signal to sensitize tumor cells to death through the redistribution of Fas into large platform of membrane rafts...
  24. ncbi request reprint Chromatographic purification of an insoluble histidine tag recombinant Ykt6p SNARE from Arabidopsis thaliana over-expressed in E. coli
    Patrick Vincent
    Laboratoire de Biogenese Membranaire, CNRS UMR 5544, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    J Chromatogr B Analyt Technol Biomed Life Sci 808:83-9. 2004
    ..Folded and subsequently purified (94% purity) recombinant protein was obtained with 82% of recovery...